L-Proline L-Lysine 275 mg / 275 mg

L-Proline L-Lysine 275 mg / 275 mg

Source Naturals4.7 (4,559 ratings)
Format:Tablet Quantity: 120 Tablet(s) · 30 servings
Goals
$14.53 $0.48 per serving

Product analysis

55 out of 100

L-Proline L-Lysine 275 mg / 275 mg combines amino acids with vitamin C to support normal collagen formation. Vitamin C also supports normal immune function, with benefits most relevant when intake is low.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality33

Vitamin C and mineral sources are named, but several amino-acid and herbal preparations are unspecified. Unknown shares of the vitamin C sources also limit a close quality comparison.

Ingredient Transparency63

Ingredient quantities are stated, but preparation details are uneven. The proportions of the vitamin C sources are missing, limiting comparison of that mixture.

Value For Money46

Vitamin C falls in a middle value range, while the full serving cost compares favorably when judged for hawthorn. The value of the amino acids and other ingredients remains uncertain.

Customer Satisfaction88

Customer feedback is strongly positive across several thousand reviews. The large review base makes the satisfaction pattern less dependent on a few individual opinions.

Product Focus67

The formula reaches beyond amino acids into vitamin C nutrition and herbal ingredients. Its clearest roles involve normal collagen and immune functions, with less support for broad extra benefits.

Format
Tablet
Container
120 Tablet(s)
Per serving
$0.48
Customer rating
4.7 · 4,559 ratings
Report analysis

Goals

Skin Health
Impact
High effect
B- Ingredient FitF PathwaysA+ EvidenceA Formulation Logic
Vitamin C · 1147 mgProline · 1.1 Gram(s)
Study evidence
Proline Disputed 4 studies
Vitamin C Supportive 53 studies
Everyday Health
Impact
High effect
C Ingredient FitD+ PathwaysB- EvidenceA+ Formulation Logic
Magnesium · 46 mgVitamin C · 1147 mg
Study evidence
Magnesium Supportive 114 studies
Vitamin C Supportive 56 studies
Immunity
Impact
High effect
C- Ingredient FitC PathwaysA+ EvidenceA- Formulation Logic
Magnesium · 46 mgVitamin C · 1147 mg
Study evidence
Lysine Supportive 2 studies
Magnesium Supportive 8 studies
Vitamin C Supportive 53 studies
Impact
High effect
C Ingredient FitD+ PathwaysA- EvidenceA+ Formulation Logic
Vitamin C · 1147 mg
Study evidence
Magnesium Supportive 41 studies
Vitamin C Supportive 50 studies
Eye Health
Impact
High effect
C Ingredient FitD PathwaysC+ EvidenceA+ Formulation Logic
Vitamin C · 1147 mg
Study evidence
Vitamin C Disputed 24 studies

Ingredients

IngredientAmount per servingScore
Calories
20 Calorie(s)
Total Carbohydrates
2 Gram(s)
Vitamin C (Calcium Ascorbate, Magnesium Ascorbate)
1147 mg 71
Calcium (Calcium Ascorbate)
66 mg
Magnesium (Magnesium Ascorbate)
46 mg
L-Lysine
1.1 Gram(s)
L-Proline
1.1 Gram(s)
Proanthodyn (Grape Seed Extract)
100 mg
Hawthorn Berry Extract
100 mg 46
Gluten Free Adults 18–50 Dairy Free Sugar Free Vegetarian
Report overview
B+ Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyD+ Value
Each serving provides 1147 mg of vitamin C at a moderate cost per gram. The vitamin C comes from Calcium Ascorbate and Magnesium Ascorbate, in undisclosed proportions. It contains sweeteners.
How this ingredient is rated

Active Ingredient Quality & Bioavailability83

The vitamin C comes from Calcium Ascorbate and Magnesium Ascorbate, in undisclosed proportions. The listed mineral ascorbates are buffered forms.
Vitamin C Chemical Form & Delivery System
The vitamin C comes from Calcium Ascorbate and Magnesium Ascorbate, in undisclosed proportions.
Gastric Comfort & pH Balance
The listed mineral ascorbates are buffered forms.

Dose, Safety & Label Transparency69

A serving provides 1147 mg of vitamin C. Sweeteners are present.
Optimal Dosage Targeting
A serving provides 1147 mg of vitamin C.
Purity & Excipient Quality
The product contains sweeteners.
Mineral & Source Transparency
The vitamin C amount and relevant mineral amounts are stated.

Value50

The cost per gram of vitamin C is moderate.
Price per Gram of Vitamin C
The cost per gram of vitamin C is moderate.
Hawthorn · 100 mg OverallScore46
F Composition And Label DisclosureB+ Commercial Price And Usability
The serving provides 100 mg of hawthorn fruit extract, with a lower whole-product cost per serving. No marker concentration or preparation ratio is available. The hawthorn species is not specified in the available information.
How this ingredient is rated

Composition and Label Disclosure29

No marker concentration or preparation ratio is available. The hawthorn species is not specified in the available information.
Marker and Preparation Disclosure
No marker concentration or preparation ratio is available.
Species Name Disclosure
The hawthorn species is not specified in the available information.

Composition and Label Disclosure

No separate preparation or amount details are evaluated in this group.

Commercial Price and Usability80

The whole-product cost per serving is lower.
Commercial Price per Labeled Serving
The whole-product cost per serving is lower.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Perioperative systemic magnesium to minimize postoperative pain: a meta-analysis of randomized controlled trials.
    De Oliveira GS; Castro-Alves LJ; Khan JH; McCarthy RJ · Anesthesiology · 2013
    Meta-analysis1,257 participants20 studies pooledEveryday Health forMagnesium
  2. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infarction: the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2).
    Woods KL; Fletcher S · Lancet (London, England) · 1994
    Randomized trial2,316 participantsEveryday Health forMagnesium
  3. Association of magnesium sulfate use with mortality in critically ill patients with sepsis: a retrospective propensity score-matched cohort study.
    Gu WJ; Duan XJ; Liu XZ; Cen Y; Tao LY; Lyu J; Yin HY · British journal of anaesthesia · 2023
    Cohort study10,999 participantsEveryday Health forMagnesium
  4. Hypomagnesemia and Mortality in Incident Hemodialysis Patients.
    Li L; Streja E; Rhee CM; Mehrotra R; Soohoo M; Brunelli SM; Kovesdy CP; Kalantar-Zadeh K · American journal of kidney diseases : the official journal of the National Kidney Foundation · 2016
    Cohort study9,359 participantsEveryday Health forMagnesium
  5. The effects of magnesium supplementation on abnormal uterine bleeding, alopecia, quality of life, and acne in women with polycystic ovary syndrome: a randomized clinical trial.
    Jaripur M; Ghasemi-Tehrani H; Askari G; Gholizadeh-Moghaddam M; Clark CCT; Rouhani MH · Reproductive biology and endocrinology : RB&E · 2022
    Randomized trial64 participantsEveryday Health forMagnesium
  6. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies.
    Aune D; Keum N; Giovannucci E; Fadnes LT; Boffetta P; Greenwood DC; Tonstad S; Vatten LJ; Riboli E; Norat T · The American journal of clinical nutrition · 2019
    Meta-analysis69 studies pooledEveryday Health forVitamin C
  7. Scientific Opinion on the substantiation of a health claim related to vitamin C and increasing non haem iron absorption pursuant to Article 14 of Regulation (EC) No 1924/2006.
    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) · EFSA journal. European Food Safety Authority · 2026
    Guideline / consensusEveryday Health forVitamin C
  8. Vitamin C Depletion and All-Cause Mortality in Renal Transplant Recipients.
    Sotomayor CG; Eisenga MF; Gomes Neto AW; Ozyilmaz A; Gans ROB; Jong WHA; Zelle DM; Berger SP; Gaillard CAJM; Navis GJ; Bakker SJ · Nutrients · 2018
    Cohort study598 participantsEveryday Health forVitamin C
  9. Associations of Serum Biomarkers of Fruit and Vegetable Intake With the Risk of Cause-Specific Mortality and All-Cause Mortality: A National Prospective Cohort Study.
    Pu L; Zhang R; Wang X; Zhao T; Sun H; Han L · Frontiers in nutrition · 2022
    Cohort study12,530 participantsEveryday Health forVitamin C
  10. Relation between plasma ascorbic acid and mortality in men and women in EPIC-Norfolk prospective study: a prospective population study. European Prospective Investigation into Cancer and Nutrition.
    Khaw KT; Bingham S; Welch A; Luben R; Wareham N; Oakes S; Day N · Lancet (London, England) · 2001
    Cohort study19,496 participantsEveryday Health forVitamin C
  11. Role of Oral Vitamin 'C' on Astigmatic Errors in Phacoemulsification.
    Mohan S; Sah K; Khattri M; Ahmad L; Sachan SK · Current eye research · 2021
    Randomized trial400 participantsEye Health forVitamin C
  12. Ascorbic acid metabolites are involved in intraocular pressure control in the general population.
    Hysi PG; Khawaja AP; Menni C; Tamraz B; Wareham N; Khaw KT; Foster PJ; Benet LZ; Spector TD; Hammond CJ · Redox biology · 2019
    Observational studyEye Health forVitamin C
  13. Nutritional modulation of cataract.
    Weikel KA; Garber C; Baburins A; Taylor A · Nutrition reviews · 2014
    Narrative reviewEye Health forVitamin C
  14. Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.
    Aoki A; Inoue M; Nguyen E; Obata R; Kadonosono K; Shinkai S; Hashimoto H; Sasaki S; Yanagi Y · Scientific reports · 2017
    Case-control study530 participantsEye Health forVitamin C
  15. Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3.
    Raimundo M; Mira F; Cachulo MDL; Barreto P; Ribeiro L; Farinha C; Laíns I; Nunes S; Alves D; Figueira J; Merle BM; Delcourt C; Santos L; Silva R · Acta ophthalmologica · 2019
    Case-control study883 participantsEye Health forVitamin C
  16. Lysine-fortified wheat flour improves the nutritional and immunological status of wheat-eating families in northern China.
    Zhao W; Zhai F; Zhang D; An Y; Liu Y; He Y; Ge K; Scrimshaw NS · Food and nutrition bulletin · 2004
    Clinical trial264 participantsImmunity forLysine
  17. Success of L-lysine therapy in frequently recurrent herpes simplex infection. Treatment and prophylaxis
    R S Griffith, D E Walsh, K H Myrmel, R W Thompson, A Behforooz · Dermatologica · 1987
    Non-randomized trial52 participantsImmunity forLysine
  18. Hypomagnesemia Is a Risk Factor for Infections after Kidney Transplantation: A Retrospective Cohort Analysis.
    Odler B; Deak AT; Pregartner G; Riedl R; Bozic J; Trummer C; Prenner A; Söllinger L; Krall M; Höflechner L; Hebesberger C; Boxler MS; Berghold A; Schemmer P; Pilz S; Rosenkranz AR · Nutrients · 2021
    Cohort study376 participantsImmunity forMagnesium
  19. Higher Intake of Dietary Magnesium Is Inversely Associated With COVID-19 Severity and Symptoms in Hospitalized Patients: A Cross-Sectional Study.
    Nouri-Majd S; Ebrahimzadeh A; Mousavi SM; Zargarzadeh N; Eslami M; Santos HO; Taghizadeh M; Milajerdi A · Frontiers in nutrition · 2022
    Cross-sectional study250 participantsImmunity forMagnesium
  20. Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronic EBV infection through NKG2D.
    Chaigne-Delalande B; Li FY; O'Connor GM; Lukacs MJ; Jiang P; Zheng L; Shatzer A; Biancalana M; Pittaluga S; Matthews HF; Jancel TJ; Bleesing JJ; Marsh RA; Kuijpers TW; Nichols KE; Lucas CL; Nagpal S; Mehmet H; Su HC; Cohen JI; Uzel G; Lenardo MJ · Science (New York, N.Y.) · 2013
    Single-arm trialImmunity forMagnesium