Selenium Synergy

Selenium Synergy

Jarrow Formulas4.8 (3,343 ratings)
Format:Capsule Quantity: 60 Capsule(s) · 60 servings
Goals

Product analysis

68 out of 100

Selenium Synergy may help fill low selenium intake to support normal immune function and the body’s antioxidant systems. Riboflavin adds support for normal nutrient metabolism.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality43

The selenium form is identified, though it does not stand out as a particular quality strength. The quality of the other named vitamin forms remains uncertain, and the glucoraphanin preparation is unstated.

Ingredient Transparency91

Ingredient amounts and most forms are disclosed, making the blend fairly easy to compare. The glucoraphanin preparation remains unstated.

Value For Money58

Selenium offers favorable value for the amount supplied. Value for the vitamin E and riboflavin portions remains uncertain.

Customer Satisfaction89

Customer feedback is very positive across a large review pool. The volume gives a broad picture of satisfaction, without establishing extra health benefits.

Product Focus80

The formula is focused on normal nutrition and antioxidant-related immune support. The clearest benefit is filling low intake, rather than providing extra protection when selenium intake is adequate.

Format
Capsule
Container
60 Capsule(s)
Per serving
$0.16
Customer rating
4.8 · 3,343 ratings
Report analysis

Goals

Immunity
Impact
High effect
B- Ingredient FitC- PathwaysA- EvidenceA+ Formulation Logic
Selenium · 200 mcg
Study evidence
Selenium Mixed 37 studies
Vitamin E Supportive 21 studies
Everyday Health
Impact
Highest effect
A- Ingredient FitB+ PathwaysB+ EvidenceA+ Formulation Logic
Selenium · 200 mcg
Study evidence
Selenium Supportive 70 studies

Ingredients

IngredientAmount per servingScore
Vitamin E (D-Alpha-Tocopheryl Succinate)
20 mg
Riboflavin
2 mg
Selenium (Methylselenocysteine)
200 mcg 77
Glucoraphanin
10 mg
Adults 18–50
Report overview
D+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value
Each serving provides 200 mcg of selenium, an amount used in clinical trials, at a moderate cost per 200 mcg. It uses Methylselenocysteine, a named form without a specific isomer or compound detail.
How this ingredient is rated

Active Ingredient Quality & Bioavailability53

The selenium comes from Methylselenocysteine, a named form without a specific isomer or compound detail.
Selenium Chemical Form
Methylselenocysteine is a named form without a specific isomer or compound detail.
Form Transparency & Isomer Specificity
The label names Methylselenocysteine but gives no more specific isomer detail.

Dose, Safety & Label Transparency100

The 200 mcg serving is an amount used in clinical trials. It leaves room below the daily upper limit for other sources.
Dosage Efficacy Sweet Spot
The serving provides 200 mcg, an amount used in clinical trials.
Safety Margin & UL Adherence
The 200 mcg serving leaves room below the 400 mcg daily upper limit for selenium from food and other sources.

Value80

The cost per 200 mcg of selenium is moderate.
Price per 200 mcg Serving
The cost per 200 mcg of selenium is moderate.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
    Cui Z; Xie R; Lu X; Schomburg L; Brenner H; Schöttker B · Redox biology · 2025
    Meta-analysis95 participants20 studies pooledEveryday Health forSelenium
  2. Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
    Jayedi A; Rashidy-Pour A; Parohan M; Zargar MS; Shab-Bidar S · Advances in nutrition (Bethesda, Md.) · 2019
    Meta-analysis507,251 participants41 studies pooledEveryday Health forSelenium
  3. The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
    Sharabati I; Qafesha RM; Hindawi MD; Amro S; Ayesh BM · Clinical endocrinology · 2024
    Meta-analysis4 studies pooledEveryday Health forSelenium
  4. Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
    Shi L; Yuan Y; Xiao Y; Long P; Li W; Yu Y; Liu Y; Liu K; Wang H; Zhou L; Yang H; Li X; He M; Wu T · Environment international · 2021
    Cohort study6,155 participantsEveryday Health forSelenium
  5. Updates on clinical studies of selenium supplementation in radiotherapy.
    Puspitasari IM; Abdulah R; Yamazaki C; Kameo S; Nakano T; Koyama H · Radiation oncology (London, England) · 2015
    Systematic review16 studies pooledEveryday Health forSelenium
  6. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  7. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  8. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  9. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  10. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium
  11. Vitamin E supplementation enhances cell-mediated immunity in healthy elderly subjects.
    Meydani SN; Barklund MP; Liu S; Meydani M; Miller RA; Cannon JG; Morrow FD; Rocklin R; Blumberg JB · The American journal of clinical nutrition · 1990
    Randomized trial32 participantsImmunity forVitamin E
  12. Immunomodulatory effects of palm-derived tocotrienol-rich fraction in healthy volunteers following influenza vaccination: A randomised clinical trial.
    Chen S; Ahmad B; Palanisamy UD; Hafid SRA; Selvaduray KR; Radhakrishnan AK · Nutrition research (New York, N.Y.) · 2026
    Randomized trial150 participantsImmunity forVitamin E
  13. Effects of supplementation with tocotrienol-rich fraction on immune response to tetanus toxoid immunization in normal healthy volunteers.
    Mahalingam D; Radhakrishnan AK; Amom Z; Ibrahim N; Nesaretnam K · European journal of clinical nutrition · 2011
    Randomized trialImmunity forVitamin E
  14. Vitamin E and beta-carotene supplementation and hospital-treated pneumonia incidence in male smokers.
    Hemilä H; Virtamo J; Albanes D; Kaprio J · Chest · 2004
    Randomized trial29,133 participantsImmunity forVitamin E
  15. Vitamin E supplementation and in vivo immune response in healthy elderly subjects. A randomized controlled trial.
    Meydani SN; Meydani M; Blumberg JB; Leka LS; Siber G; Loszewski R; Thompson C; Pedrosa MC; Diamond RD; Stollar BD · JAMA · 1997
    Randomized trial88 participantsImmunity forVitamin E