Methyl B-12 Methyl Folate Lonzenge Natural Cherry Flavor

Methyl B-12 Methyl Folate Lonzenge Natural Cherry Flavor

Solaray4.8 (1,231 ratings)
Format:Lozenge Quantity: 60 Liquid(s) · 60 servings
Goals
$23.79 $0.39 per serving

Product analysis

79 out of 100

Methyl B-12 Methyl Folate Lonzenge Natural Cherry Flavor may help fill B12 and folate gaps that contribute to tiredness and support normal blood and nerve functions. Its folate also offers good value, making the pair appealing for focused nutritional support.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality70

The folate is supplied in a readily usable form. B12 is also identified by form, but its form-specific quality remains uncertain.

Ingredient Transparency100

Both amounts and forms are clearly disclosed. That makes the two-nutrient formula straightforward to compare with alternatives.

Value For Money70

The folate offers good value at the full serving cost. B12 value remains uncertain, so the folate comparison should not be treated as a complete price assessment.

Customer Satisfaction84

Ratings are very positive across more than a thousand customers. Specific experiences are not described, leaving the reasons behind satisfaction unclear.

Product Focus73

The pair is most relevant to nutritional gaps affecting blood formation, energy and nerve function. Its many intended uses reach beyond the benefits established for people who already get enough.

Format
Lozenge
Container
60 Liquid(s)
Per serving
$0.39
Customer rating
4.8 · 1,231 ratings
Report analysis

Goals

Everyday Health
Impact
Highest effect
A Ingredient FitC PathwaysB+ EvidenceA+ Formulation Logic
Folate · 800 mcgVitamin B12 · 2000 mcg

Folate and B12 contribute to normal blood formation and related nutrient metabolism. They can help fill a dietary gap, but their normal functions do not demonstrate extra energy or broader health improvements when intake is adequate. The methylated forms do not establish superiority, and the high B12 amount does not demonstrate proportionally greater benefit.

How this product is rated for Everyday Health

Ingredient fit91

The relevant declared amounts reach the saved comparison endpoints; larger quantities do not establish larger health benefits.
Goal fit
The relevant ingredients give this formula a focused connection to the supplied general-health roles.
Dose adequacy
The relevant declared amounts reach the comparison amounts; larger quantities do not establish larger health benefits.

Pathways60

The strongest contribution concerns blood formation and related metabolism. Other meaningful coverage is limited to the named nutrient roles.
Depth
The strongest finding concerns blood formation and related metabolism, based on the relevant ingredients and their supplied amounts.
Breadth
Meaningful coverage extends to blood formation and related metabolism.

Evidence82

Vitamin B9 (Folate) provides the leading evidence contribution. Nutritional functions and the saved preparation findings do not establish broad health improvements above adequate intake.
Evidence strength
Vitamin B9 (Folate) leads the evidence contribution; its nutrient role does not establish extra benefit above adequate intake.
Studied preparation
The included preparations meet the preparation criteria; this does not establish superiority of a particular form.

Formulation logic100

The included ingredients can contribute without a missing required partner, and no configured conflict was found. Their amounts pass the saved minimum contribution check.
Partner coverage
The included ingredients can contribute independently or have their required partners; no extra benefit from combining them is established.
Conflicts
No configured ingredient conflict was identified in the supplied facts.
Effective doses
The included amounts all meet the minimum amount used in these findings; that threshold is not a proven clinical dose.
Study evidence
Folate Supportive 80 studies
Hair Health
Impact
High effect
A Ingredient FitF PathwaysB EvidenceA+ Formulation Logic

Folate supports cell division, while vitamin B12 is a B-complex nutrient commonly included in hair formulas. These roles do not establish independent improvement in hair growth. Both amounts reach the saved comparison benchmarks, but this does not turn nutrient-function evidence into demonstrated regrowth or broader coverage of hair-loss mechanisms.

How this product is rated for Hair Health

Ingredient fit91

The contributing amounts reach their saved comparison benchmarks; these benchmarks are not proven hair-growth doses.
Goal fit
The formula includes ingredients connected to hair health, alongside broader nutritional or other uses that reduce its specific focus.
Dose adequacy
The contributing amounts reach their saved comparison benchmarks; these benchmarks are not proven hair-growth doses.

Pathways0

No contribution is established across the assessed hair pathways.
Depth
No contribution is established across the assessed hair pathways.
Breadth
No assessed pathway reaches the saved coverage threshold, so broad support is not established.

Evidence78

Vitamin B12 leads the saved evidence finding, but the supplied context does not establish independent routine hair regrowth.
Evidence strength
Vitamin B12 leads the saved evidence finding, but the supplied context does not establish independent routine hair regrowth.
Studied preparation
The contributing forms meet the saved preparation criteria, without establishing a hair-growth benefit beyond the ingredient-specific evidence.

Formulation logic100

The contributing ingredients have no missing required partners or configured conflicts. Their amounts meet the saved minimum comparison threshold.
Partner coverage
No required ingredient partner is missing among the contributing ingredients; this does not establish an added combination benefit.
Conflicts
No configured ingredient conflict was identified in the supplied calculation.
Effective doses
All contributing ingredients meet the saved minimum amount threshold; this is a comparison finding, not proof of clinical effectiveness.
Study evidence
Folate Mixed 15 studies

Ingredients

IngredientAmount per servingScore
Folate (Quatrefolic (6S)-5-Methyltetrahydrofolate Glucosamine Salt)
800 mcg 100
Vitamin B12 (Methylcobalamin)
2000 mcg 96
Adults 18–50
Report overview
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value
The serving provides 2,000 mcg of vitamin B12 as methylcobalamin, a high amount in this comparison. The whole-product price works out to about $0.20 per 1,000 mcg of B12.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

Methylcobalamin is an active form of vitamin B12.
Bioactive B12 Form Selection
Methylcobalamin is an active form of vitamin B12.

Dose, Safety & Label Transparency100

The serving contains 2,000 mcg of B12, a high amount in this comparison. Its methylcobalamin form is identified.
Therapeutic Dosage Level
The 2,000 mcg per serving is a high amount in this comparison. A higher amount is not necessarily needed by everyone.
Label and Form Transparency
The listed 2,000 mcg per serving is identified as methylcobalamin.

Value80

The whole-product price works out to about $0.20 per 1,000 mcg of B12; it reflects the price of the full product.
Price per 1,000 mcg B12
The whole-product price works out to about $0.20 per 1,000 mcg of B12; it reflects the price of the full product.
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value
A serving provides 800 mcg of folate as L-methylfolate. L-methylfolate bypasses the MTHFR conversion step, and the whole-product serving costs about $0.40.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

L-methylfolate is an active folate form that bypasses the MTHFR conversion step. A branded folate source is indicated in the saved evaluation, but its name is not provided in the saved facts.
Folate Form Hierarchy
L-methylfolate is an active folate form that bypasses the MTHFR conversion step.
Patented Sources & Isomeric Purity
A branded folate source is indicated in the saved evaluation, but its name is not provided in the saved facts.

Dose, Safety & Label Transparency100

The saved facts give 800 mcg of folate per serving, without a DFE amount.
Folate Dosage by Declared Basis
The saved facts give 800 mcg of folate per serving, without a DFE amount.

Value100

A whole-product serving costs about $0.40.
Price per Bioavailable Serving
A whole-product serving costs about $0.40.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsEveryday Health forFolate
  2. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsEveryday Health forFolate
  3. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsEveryday Health forFolate
  4. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewEveryday Health forFolate
  5. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledEveryday Health forFolate
  6. Oral Vitamin B12 versus Placebo for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Gynecological Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Insin P; Chaiwongsa T; Prueksaritanond N · Asian Pacific journal of cancer prevention : APJCP · 2026
    Randomized trial40 participantsEveryday Health forVitamin B12
  7. Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial.
    Didangelos T; Karlafti E; Kotzakioulafi E; Margariti E; Giannoulaki P; Batanis G; Tesfaye S; Kantartzis K · Nutrients · 2021
    Randomized trial90 participantsEveryday Health forVitamin B12
  8. A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.
    Xu G; Lv ZW; Feng Y; Tang WZ; Xu GX · Pain medicine (Malden, Mass.) · 2014
    Randomized trial98 participantsEveryday Health forVitamin B12
  9. Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
    Xǔ G; Xu S; Tang WZ; Xú G; Cheng C; Xu J · Pain medicine (Malden, Mass.) · 2017
    Randomized trial204 participantsEveryday Health forVitamin B12
  10. The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.
    Nozari E; Ghavamzadeh S; Razazian N · Clinical nutrition research · 2022
    Clinical trial50 participantsEveryday Health forVitamin B12
  11. Hair Loss After Metabolic and Bariatric Surgery: a Systematic Review and Meta-analysis.
    Zhang W; Fan M; Wang C; Mahawar K; Parmar C; Chen W; Yang W; Global Bariatric Research Collaborative · Obesity surgery · 2021
    Meta-analysis2,538 participants18 studies pooledHair Health forFolate
  12. Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.
    Al-Fawaeir S; Al-Odat I · Diseases (Basel, Switzerland) · 2025
    Case-control study200 participantsHair Health forFolate Hair Health forVitamin B12
  13. Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer.
    Saini A; Norman AR; Cunningham D; Chau I; Hill M; Tait D; Hickish T; Iveson T; Lofts F; Jodrell D; Ross PJ; Oates J · British journal of cancer · 2003
    Randomized trialHair Health forFolate
  14. Role of oxaliplatin combined with 5-fluorouracil and folinic acid in the first- and second-line treatment of advanced colorectal cancer.
    Jonker D; Rumble RB; Maroun J; Gastrointestinal Cancer Disease Site Groupof Cancer Care Ontario’s Program in Evidence-Based Care · Current oncology (Toronto, Ont.) · 2012
    Randomized trialHair Health forFolate
  15. Phase I-II study of vinorelbine in combination with 5-fluorouracil and folinic acid as first-line chemotherapy in metastatic breast cancer: a regimen with a low subjective toxic burden.
    Nolè F; de Braud F; Aapro M; Minchella I; De Pas TM; Zampino MG; Monti S; Andreoni G; Goldhirsch A · Annals of oncology : official journal of the European Society for Medical Oncology · 1997
    Randomized trialHair Health forFolate
  16. Factors Associated with Premature Hair Graying in a Young Indian Population.
    Chakrabarty S; Krishnappa PG; Gowda DG; Hiremath J · International journal of trichology · 2016
    Case-control study74 participantsHair Health forVitamin B12
  17. Risk Factors for Pediatric Alopecia Areata: Clinical and Biochemical Findings from a Case - Control Study.
    İritaş SY · Dermatology practical & conceptual · 2026
    Case-control study600 participantsHair Health forVitamin B12
  18. Hair Loss After Laparoscopic Sleeve Gastrectomy.
    Katsogridaki G; Tzovaras G; Sioka E; Perivoliotis K; Zachari E; Magouliotis D; Tasiopoulou V; Chatedaki C; Zacharoulis D · Obesity surgery · 2019
    Cohort study50 participantsHair Health forVitamin B12
  19. Demographic Characteristics and Association of Serum Vitamin B12, Ferritin and Thyroid Function with Premature Canities in Indian Patients from an Urban Skin Clinic of North India: A Retrospective Analysis of 71 Cases.
    Sonthalia S; Priya A; Tobin DJ · Indian journal of dermatology · 2022
    Cross-sectional study71 participantsHair Health forVitamin B12