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Ultra Sugar Control

NaturesPlus
4.5
★ ★ ★ ★ ★
(268 ratings)
Chromium 500 mcg
Alanine 250 mg
Glutamine 250 mg
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Score71

A multi-ingredient glucose and appetite-support formula with substantial chromium, gymnema, and garcinia. Medication interactions and liver-safety concerns require care.

How scoring works
Quantity:60 Tablet(s) • (30 servings)
Goals:
Metabolism Boost
Weight Loss

Score 71

A multi-ingredient glucose and appetite-support formula with substantial chromium, gymnema, and garcinia. Medication interactions and liver-safety concerns require care.

How scoring works
$31.41($1.04 per serving)
iHerb
$ 31.41
Pure Formulas
$ 31.41
iHerb
$ 31.41
Vitacost
$ 31.43
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Analysis

The two-tablet serving provides 500 mcg ChromeMate chromium, 200 mg gymnema, 500 mg Citrimax garcinia extract, and 400 mg Rehmannia. The combination addresses glucose handling and appetite-related pathways.

Gymnema is linked to gymnemic acids, but the supplied data do not state a standardized percentage. Glutamine and alanine are each 250 mg, amounts that add little compared with the botanical and chromium core.

The formula may suit carefully monitored users seeking multi-pathway metabolic support. It is not a simple weight-loss solution, and glucose-lowering medication or liver risk can materially change the safety assessment.

Who is it for
  • Adults seeking multi-pathway glucose support
  • Users who are not combining it with glucose-lowering medicine without supervision
  • People willing to monitor botanical tolerance
Best for
  • Glucose-metabolism support
  • Chromium supplementation
  • Appetite-related botanical support

Pros

  • Uses branded ChromeMate chromium
  • Includes gymnema and Citrimax garcinia
  • Provides clear main ingredient amounts
  • Broader pathway coverage than chromium alone

Cons

  • Chromium amount is high
  • Gymnema standardization is incomplete
  • Glutamine and alanine are modest
  • Weight-loss evidence is mixed
  • Requires two tablets

Warnings

  • Chromium and gymnema may intensify insulin or sulfonylurea effects
  • People using glucose-lowering medicines should monitor with their prescriber
  • Garcinia carries a rare liver-injury concern
  • Stop use and seek care for jaundice, dark urine, severe fatigue, or upper-abdominal pain
  • Do not combine it casually with other high-chromium supplements

Nutrient quality

75 High impact

Branded chromium supports good form quality, while botanical standardization remains incomplete. The main glucose-support ingredients are meaningful, but small amino acids and uncertain garcinia value weaken the formula.

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Ingredient transparency

80 High impact

Active ingredient amounts and the serving count are clear from the supplied facts. Complete directions, non-active ingredients, and some source details are missing.

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Customer satisfaction

68 High impact

The aggregate rating is strong and supported by a moderate feedback volume. Specific experience details are missing, so recurring problems and purpose fit remain uncertain.

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Value for money

57 Moderate impact

Relevant glucose-support ingredients add quality, but uncertain botanicals weaken the premium case. Serving value is weak relative to the formula’s uncertain added effects.

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Goals

Metabolism Boost
Impact
High effect
B Goal FitB- Strength of SupportB- CoverageC+ Formula Quality

Chromium and gymnema give the formula direct relevance to insulin signaling and glucose management. Garcinia broadens the concept toward appetite and fat metabolism, but its human evidence is inconsistent.

Missing botanical standardization limits confidence in effective active amounts. Chromium and gymnema may compound the effects of insulin or sulfonylureas, while garcinia has rare liver-injury reports.

Study evidence
Chromium Supportive 47 studies
Weight Loss
Impact
Moderate effect
D+ Goal FitC+ Strength of SupportD+ CoverageC Formula Quality

Chromium, garcinia, and gymnema create a broader glucose-and-appetite strategy than a basic chromium formula. Still, support for weight loss is mixed, and the product lacks fiber, protein, or a well-established thermogenic.

Doses are transparent and several actives are present at material supplemental amounts, though their likely impact remains modest. Because chromium and gymnema may lower blood sugar, people using insulin or other glucose-lowering medicines should watch for low blood sugar with their prescriber.

Study evidence
Chromium No effect 24 studies

Ingredients

IngredientAmount per serving
Calcium (Calcium Hydroxycitrate)
75 mg
Chromium (ChromeMate)
500 mcg
Citrimax (Garcinia cambogia Fruit Extract)
500 mg
Rehmannia glutinosa
400 mg
L-Glutamine
250 mg
L-Alanine
250 mg
Gymnema sylvestre (Gymnemic Acids)
200 mg
Gluten Free Adults 18–50 No Allergies Vegetarian
Report overview
A+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyB Value

Chromium polynicotinate is a highly bioavailable organic form. The 500 mcg elemental chromium serving falls in the preferred potency range. The high-potency serving produces good cost efficiency per standard chromium amount.

Alanine · 250 mg OverallScore76
B+ Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD+ Value

The formula clearly identifies L-Alanine and supplies an above-median amount for the collection. The exact dose and two-tablet serving make daily use straightforward to assess. Cost efficiency is moderate because the higher serving cost offsets the stronger dose.

Glutamine · 250 mg OverallScore44
B- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

The formula clearly discloses L-glutamine, but the amount is very low for glutamine-specific use. Its botanical and mineral ingredients serve a different primary purpose. A substantial glutamine intake would require an impractical tablet count and deliver poor glutamine value.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Improved meta-analytic methods show no effect of chromium supplements on fasting glucose.
    Bailey CH · Biological trace element research · 2014
    Meta-analysis809 participants16 studies pooledMetabolism Boost forChromium
  2. A pilot study of chromium picolinate for weight loss.
    Yazaki Y; Faridi Z; Ma Y; Ali A; Northrup V; Njike VY; Liberti L; Katz DL · Journal of alternative and complementary medicine (New York, N.Y.) · 2010
    Randomized trial80 participantsWeight Loss forChromium
  3. Chromium supplementation in non-obese non-diabetic subjects is associated with a decline in insulin sensitivity.
    Masharani U; Gjerde C; McCoy S; Maddux BA; Hessler D; Goldfine ID; Youngren JF · BMC endocrine disorders · 2013
    Randomized trial31 participantsMetabolism Boost forChromium
  4. Chromium picolinate balances the metabolic and clinical markers in nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled trial.
    Kooshki F; Moradi F; Karimi A; Niazkar HR; Khoshbaten M; Maleki V; Pourghassem Gargari B · European journal of gastroenterology & hepatology · 2021
    Randomized trial46 participantsWeight Loss forChromium
  5. The Effects of Supplementation with Chromium on Insulin Resistance Indices in Women with Polycystic Ovarian Syndrome: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
    Heshmati J; Omani-Samani R; Vesali S; Maroufizadeh S; Rezaeinejad M; Razavi M; Sepidarkish M · Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2018
    Meta-analysis268 participants5 studies pooledMetabolism Boost forChromium
  6. Association Between Essential and Non-essential Metals, Body Composition, and Metabolic Syndrome in Adults.
    Ngu YJ; Skalny AV; Tinkov AA; Tsai CS; Chang CC; Chuang YK; Nikolenko VN; Zotkin DA; Chiu CF; Chang JS · Biological trace element research · 2022
    Cross-sectional study150 participantsWeight Loss forChromium
  7. Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes.
    Anderson RA; Cheng N; Bryden NA; Polansky MM; Cheng N; Chi J; Feng J · Diabetes · 1997
    Randomized trial180 participantsMetabolism Boost forChromium
  8. The Influences of Chromium Supplementation on Metabolic Status in Patients with Type 2 Diabetes Mellitus and Coronary Heart Disease.
    Farrokhian A; Mahmoodian M; Bahmani F; Amirani E; Shafabakhsh R; Asemi Z · Biological trace element research · 2021
    Randomized trial64 participantsWeight Loss forChromium
  9. Chromium effects on glucose tolerance and insulin sensitivity in persons at risk for diabetes mellitus.
    Ali A; Ma Y; Reynolds J; Wise JP; Inzucchi SE; Katz DL · Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2011
    Randomized trial59 participantsMetabolism Boost forChromium
  10. Chromium picolinate supplementation in women: effects on body weight, composition, and iron status.
    Lukaski HC; Siders WA; Penland JG · Nutrition (Burbank, Los Angeles County, Calif.) · 2007
    Randomized trial83 participantsWeight Loss forChromium
  11. Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes.
    Martin J; Wang ZQ; Zhang XH; Wachtel D; Volaufova J; Matthews DE; Cefalu WT · Diabetes care · 2006
    Randomized trial37 participantsMetabolism Boost Weight Loss forChromium
  12. Comparison of nutritional supplements in improving glycolipid metabolism and endocrine function in polycystic ovary syndrome: a systematic review and network meta-analysis.
    Hu X; Wang W; Su X; Peng H; Tan Z; Li Y; Huang Y · PeerJ · 2023
    Meta-analysis2,362 participants41 studies pooledMetabolism Boost forChromium
  13. Chromium picolinate reduces insulin resistance in polycystic ovary syndrome: Randomized controlled trial.
    Ashoush S; Abou-Gamrah A; Bayoumy H; Othman N · The journal of obstetrics and gynaecology research · 2017
    Randomized trial100 participantsWeight Loss forChromium
  14. [Chromium supplementation in patients with type 2 diabetes and high risk of type 2 diabetes: a meta-analysis of randomized controlled trials].
    San Mauro-Martin I; Ruiz-León AM; Camina-Martín MA; Garicano-Vilar E; Collado-Yurrita L; Mateo-Silleras Bd; Redondo Del Río Mde P · Nutricion hospitalaria · 2017
    Meta-analysis13 studies pooledMetabolism Boost forChromium
  15. Chromium picolinate does not improve key features of metabolic syndrome in obese nondiabetic adults.
    Iqbal N; Cardillo S; Volger S; Bloedon LT; Anderson RA; Boston R; Szapary PO · Metabolic syndrome and related disorders · 2009
    Randomized trial63 participantsMetabolism Boost Weight Loss forChromium
  16. Systematic review and meta-analysis of the efficacy and safety of chromium supplementation in diabetes.
    Suksomboon N; Poolsup N; Yuwanakorn A · Journal of clinical pharmacy and therapeutics · 2015
    Meta-analysis25 studies pooledMetabolism Boost forChromium
  17. Effect of chromium supplementation on the glucose homeostasis and anthropometry of type 2 diabetic patients: Double blind, randomized clinical trial: Chromium, glucose homeostasis and anthropometry.
    Guimarães MM; Carvalho AC; Silva MS · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2017
    Randomized trial56 participantsWeight Loss forChromium
  18. Chromium treatment has no effect in patients with poorly controlled, insulin-treated type 2 diabetes in an obese Western population: a randomized, double-blind, placebo-controlled trial.
    Kleefstra N; Houweling ST; Jansman FG; Groenier KH; Gans RO; Meyboom-de Jong B; Bakker SJ; Bilo HJ · Diabetes care · 2006
    Randomized trial46 participantsWeight Loss forChromium
  19. Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Jamilian M; Asemi Z · Annals of nutrition & metabolism · 2016
    Randomized trial64 participantsMetabolism Boost forChromium
  20. A Comprehensive insight into the effect of chromium supplementation on oxidative stress indices in diabetes mellitus: A systematic review.
    Kooshki F; Tutunchi H; Vajdi M; Karimi A; Niazkar HR; Shoorei H; Pourghassem Gargari B · Clinical and experimental pharmacology & physiology · 2024
    Systematic review33 studies pooledMetabolism Boost forChromium
  21. Chromium supplementation and polycystic ovary syndrome: A systematic review and meta-analysis.
    Fazelian S; Rouhani MH; Bank SS; Amani R · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2018
    Meta-analysis351 participants7 studies pooledWeight Loss forChromium