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Premium Milk Thistle 160 mg

Natural Factors
4.7
★ ★ ★ ★ ★
(1455 ratings)
Milk Thistle 160 mg
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Score81
Phytosome delivery is the main advantage, while the undisclosed silybin yield limits exact potency comparison.
How scoring works
Quantity:60 Capsule(s) • (60 servings)
Goals:
Detoxification

Score 81

Phytosome delivery is the main advantage, while the undisclosed silybin yield limits exact potency comparison.
How scoring works
$18.17($0.30 per serving)
Amazon
$ 18.17
Vitacost
$ 18.17
iHerb
$ 18.17
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Analysis

Siliphos binds silybin to phosphatidylcholine, a delivery approach intended to improve absorption over ordinary dry extract. The 160 mg complex is clearly stated and the formula avoids an unnecessary botanical blend.

The label does not separate the amount of silybin from the total complex weight. Forty milligrams of calcium from dicalcium phosphate adds little to the main purpose.

People who value absorption-oriented milk thistle delivery are the clearest fit. Users who compare products by exact active-marker dose may want fuller silybin disclosure.

Who is it for
  • Adults seeking absorption-oriented milk thistle
  • People who prefer a focused phytosome formula
  • Users who tolerate phosphatidylcholine complexes
Best for
  • Silybin phytosome supplementation
  • Focused liver-support use
  • Enhanced-delivery milk thistle intake

Pros

  • Uses a silybin-phosphatidylcholine complex
  • Focused formula with few actives
  • Clearly states total complex weight

Cons

  • Actual silybin yield is not disclosed
  • Calcium addition is nutritionally small
  • Cannot compare marker dose precisely

Warnings

  • Milk thistle may cause digestive upset or allergy in people sensitive to ragweed-family plants.
  • Phosphatidylcholine-containing products may cause stomach discomfort in sensitive users.
  • The 40 mg calcium amount can contribute to timing concerns with levothyroxine or certain antibiotics, although it is modest.

Nutrient quality

90 Highest impact

The silybin-phosphatidylcholine phytosome is an absorption-enhanced and well-regarded milk thistle form. The complex weight is disclosed, but the actual silybin yield is not stated.

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Ingredient transparency

76 High impact

Active ingredients generally have stated amounts and no proprietary blend hides a dose. Serving counts are available, while full directions and the other-ingredients list are missing.

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Customer satisfaction

68 High impact

The supplied aggregate rating is strong and the rating volume provides some confidence in that metric. No comment-level evidence is available to assess recurring complaints or confirm how experience matches the intended purpose.

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Value for money

89 Highest impact

Premium delivery technology and reasonable serving value support the asking position. The formula compares well when absorption quality matters more than a plainly stated active yield.

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Goals

Detoxification
Detoxification
Impact
High effect
A- Goal FitD+ Strength of SupportD+ CoverageA+ Formula Quality
Milk Thistle · 160 mg

A silybin-phosphatidylcholine phytosome provides a targeted, absorption-enhanced milk thistle approach to liver support. The delivery technology is a meaningful advantage over a basic dry extract.

The label gives only the complex weight and not its actual silybin or silymarin yield, so dose adequacy remains uncertain. The formula is focused but does not cover glutathione production, methylation, or biliary support.

Study evidence
Milk Thistle Supportive 46 studies

Ingredients

IngredientAmount per serving
Calcium (Dicalcium Phosphate)
 40 mg
Siliphos Milk Thistle Phytosome (Silybin-Phosphatidylcholine complex)
 160 mg
Gluten Free Adults 18–50 Vegan Dairy Free Sugar Free Vegetarian
Report overview
Milk Thistle (Silybin-Phosphatidylcholine complex) · 160 mg OverallScore46
C Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyA+ Value

The Siliphos silybin-phosphatidylcholine complex offers premium absorption technology. The label does not disclose the actual silymarin yield, so active-dose adequacy cannot be confirmed. A low serving cost makes the premium delivery unusually good value.

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84 Performance

Milk Thistle

Kroeger Herb Products Co.
<p>A separate silymarin amount from milk thistle seed makes potency unusually easy to assess. The clearer active profile or delivery form makes potency easier to judge than in the original, though any broader companion-ingredient role may be lost.</p>
82 Performance

Super Milk Thistle

Nature's Way
<p>Well-disclosed silymarin and silybin amounts form a strong milk thistle core, with artichoke adding relevant bile support. The clearer active profile or delivery form makes potency easier to judge than in the original, though any broader companion-ingredient role may be lost.</p>
86 Performance

Milk Thistle Extract 175 mg

Lake Avenue Nutrition
<p>A meaningful total silymarin amount from milk thistle seed makes potency straightforward to assess. The clearer active profile or delivery form makes potency easier to judge than in the original, though any broader companion-ingredient role may be lost.</p>
87 Budget

Milk Thistle Extract 175 mg

Lake Avenue Nutrition
<p>A meaningful total silymarin amount from milk thistle seed makes potency straightforward to assess. It costs less per serving than the original, while differences in extract amount, delivery format, or companion herbs should guide the final choice.</p>
80 Budget

Silymarin Complex

California Gold Nutrition
<p>Milk thistle anchors a coherent liver-support combination with dandelion, artichoke, turmeric, ginger, and black pepper. It costs less per serving than the original, while differences in extract amount, delivery format, or companion herbs should guide the final choice.</p>
78 Budget

Milk Thistle 30:1 Extract

Jarrow Formulas
<p>A concentrated single-ingredient extract provides focused liver-support value at a very accessible serving cost. It costs less per serving than the original, while differences in extract amount, delivery format, or companion herbs should guide the final choice.</p>
85 Value

Milk Thistle

Paradise
<p>A substantial stated silymarin amount provides focused milk thistle potency in a simple formula. The balance of disclosed milk-thistle quality and serving economy offers a favorable value trade-off, with formula breadth and delivery form remaining practical differences.</p>
84 Value

Milk Thistle

Nature's Answer
<p>A meaningful stated silymarin amount is paired with a small whole-herb component in a focused formula. The balance of disclosed milk-thistle quality and serving economy offers a favorable value trade-off, with formula breadth and delivery form remaining practical differences.</p>
79 Value

Milk Thistle

Solgar
<p>A standardized extract paired with whole milk thistle powder gives the formula a sensible, focused structure. The balance of disclosed milk-thistle quality and serving economy offers a favorable value trade-off, with formula breadth and delivery form remaining practical differences.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  2. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  3. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  4. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle
  5. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle