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Detox Support

4.7
★ ★ ★ ★ ★
(3163 ratings)
Milk Thistle 350 mg
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Score56
A long-supply milk thistle-and-kutki formula offers reasonable value. Proprietary blends and absent silymarin potency remain significant limitations.
How scoring works
Capsule
Quantity:180 Capsule(s) • (90 servings)
Goals:
Detoxification

Score 56

A long-supply milk thistle-and-kutki formula offers reasonable value. Proprietary blends and absent silymarin potency remain significant limitations.
How scoring works

Also available as

1 option
60 servings Milk Thistle 350 mg • 60 Capsule(s) • 30 servings $9.53 ($0.31 per serving)
$22.59($0.25 per serving)
iHerb
$ 22.59
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Analysis

The two-capsule serving includes 350 mg milk thistle seed extract and 200 mg kutki root extract. Ninety servings make this the longer-supply version of the formula.

The 300 mg liver-support blend and 23 mg absorption blend do not identify their components. Silymarin yield is also absent, so the main extract cannot be compared by active potency.

Serving value is reasonable for users who have reviewed the complete label. Transparency remains too limited for people managing medications or overlapping botanical products.

Who is it for
  • Adults who can review every proprietary blend ingredient
  • People seeking a longer supply of milk thistle with kutki
  • Users comfortable taking two capsules
Best for
  • Longer-term botanical use
  • Milk thistle and kutki combination
  • Serving value after full label review

Pros

  • 350 mg milk thistle extract
  • 200 mg kutki is disclosed
  • Ninety servings
  • Two-capsule serving
  • Better value than the smaller package

Cons

  • Two proprietary blends
  • No silymarin percentage
  • Hidden ingredients limit interaction review
  • Absorption blend cannot be evaluated

Warnings

  • Kutki may be unsuitable with bile-duct obstruction or symptomatic gallstones.
  • Undisclosed blend ingredients prevent reliable screening for allergens and medication interactions.
  • Milk thistle may trigger reactions in people sensitive to ragweed-family plants.

Nutrient quality

53 Moderate impact

Milk thistle and kutki provide a coherent core for the intended use. Unstandardized extracts and opaque blends sharply limit confidence in dose quality.

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Ingredient transparency

41 Lower impact

Named active amounts and blend totals provide partial formula detail. Hidden components, vague naming, incomplete usage, and absent excipients undermine transparency.

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Customer satisfaction

69 High impact

The aggregate satisfaction signal is favorable and has some support from the supplied volume. Specific experience details are absent, so complaint patterns and purpose fit cannot be confirmed.

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Value for money

68 High impact

A long supply and accessible serving value improve competitiveness. Opaque blends and unverified active yields remain important quality limitations.

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Report analysis

Goals

Detoxification
Detoxification
Impact
Moderate effect
B- Goal FitD- Strength of SupportD+ CoverageD+ Formula Quality
Milk Thistle · 350 mg

Milk thistle and kutki provide a direct liver and bile-support focus, giving the formula meaningful detoxification alignment. Evidence is limited by missing silymarin standardization and proprietary blends that hide the identity or amount of additional actives.

The listed milk thistle and kutki amounts suggest some potential depth, but the actual active yield and value of the absorption blend remain uncertain. Kutki may promote bile flow and may be unsuitable for people with a blocked bile duct or symptomatic gallstones.

Study evidence
Milk Thistle Supportive 46 studies

Ingredients

IngredientAmount per serving
Milk Thistle Seed Extract (Silymarin)
 350 mg
Proprietary Liver Support Blend
300 mg
Kutki Root Extract
200 mg
Proprietary Absorption Blend
23 mg
Adults 18–50 Dairy Free
Report overview
Milk Thistle (Silymarin) · 350 mg OverallScore28
D- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyC Value

The seed extract is clearly identified, but the label does not state its silymarin standardization or active yield. An undisclosed absorption blend does not establish a proven delivery advantage. The low serving cost is appealing, though uncertain potency limits confidence in value.

View ingredientView products
Loading alternative details
84 Performance

Milk Thistle

Kroeger Herb Products Co.
<p>A separate silymarin amount from milk thistle seed makes potency unusually easy to assess. The clearer active profile or delivery form makes potency easier to judge than in the original, though any broader companion-ingredient role may be lost.</p>
82 Performance

Super Milk Thistle

Nature's Way
<p>Well-disclosed silymarin and silybin amounts form a strong milk thistle core, with artichoke adding relevant bile support. The clearer active profile or delivery form makes potency easier to judge than in the original, though any broader companion-ingredient role may be lost.</p>
86 Performance

Milk Thistle Extract 175 mg

Lake Avenue Nutrition
<p>A meaningful total silymarin amount from milk thistle seed makes potency straightforward to assess. The clearer active profile or delivery form makes potency easier to judge than in the original, though any broader companion-ingredient role may be lost.</p>
87 Budget

Milk Thistle Extract 175 mg

Lake Avenue Nutrition
<p>A meaningful total silymarin amount from milk thistle seed makes potency straightforward to assess. It costs less per serving than the original, while differences in extract amount, delivery format, or companion herbs should guide the final choice.</p>
80 Budget

Silymarin Complex

California Gold Nutrition
<p>Milk thistle anchors a coherent liver-support combination with dandelion, artichoke, turmeric, ginger, and black pepper. It costs less per serving than the original, while differences in extract amount, delivery format, or companion herbs should guide the final choice.</p>
78 Budget

Milk Thistle 30:1 Extract

Jarrow Formulas
<p>A concentrated single-ingredient extract provides focused liver-support value at a very accessible serving cost. It costs less per serving than the original, while differences in extract amount, delivery format, or companion herbs should guide the final choice.</p>
85 Value

Milk Thistle

Paradise
<p>A substantial stated silymarin amount provides focused milk thistle potency in a simple formula. The balance of disclosed milk-thistle quality and serving economy offers a favorable value trade-off, with formula breadth and delivery form remaining practical differences.</p>
84 Value

Milk Thistle

Nature's Answer
<p>A meaningful stated silymarin amount is paired with a small whole-herb component in a focused formula. The balance of disclosed milk-thistle quality and serving economy offers a favorable value trade-off, with formula breadth and delivery form remaining practical differences.</p>
79 Value

Milk Thistle

Solgar
<p>A standardized extract paired with whole milk thistle powder gives the formula a sensible, focused structure. The balance of disclosed milk-thistle quality and serving economy offers a favorable value trade-off, with formula breadth and delivery form remaining practical differences.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury.
    Shahsavari K; Ardekani SS; Ardekani MRS; Esfahani MM; Kazemizadeh H; Jamialahmadi T; Iranshahi M; Khanavi M; Hasanpour M · BMC complementary medicine and therapies · 2025
    Meta-analysis3,545 participants55 studies pooledDetoxification forMilk Thistle
  2. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle
  3. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  4. A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury.
    Luangchosiri C; Thakkinstian A; Chitphuk S; Stitchantrakul W; Petraksa S; Sobhonslidsuk A · BMC complementary and alternative medicine · 2016
    Randomized trial55 participantsDetoxification forMilk Thistle
  5. Effect of 8 Weeks milk thistle powder (silymarin extract) supplementation on fatty liver disease in patients candidates for bariatric surgery.
    Mirhashemi SH; Hakakzadeh A; Yeganeh FE; Oshidari B; Rezaee SP · Metabolism open · 2022
    Observational studyDetoxification forMilk Thistle
  6. A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis.
    El-Kamary SS; Shardell MD; Abdel-Hamid M; Ismail S; El-Ateek M; Metwally M; Mikhail N; Hashem M; Mousa A; Aboul-Fotouh A; El-Kassas M; Esmat G; Strickland GT · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2009
    Randomized trial105 participantsDetoxification forMilk Thistle
  7. Evaluation of Hepatoprotective Effect of Silymarin Among Under Treatment Tuberculosis Patients: A Randomized Clinical Trial.
    Marjani M; Baghaei P; Kazempour Dizaji M; Gorji Bayani P; Fahimi F; Tabarsi P; Velayati AA · Iranian journal of pharmaceutical research : IJPR · 2016
    Randomized trial70 participantsDetoxification forMilk Thistle
  8. The hepatorenal protective effects of silymarin in cancer patients receiving chemotherapy: a randomized, placebo-controlled trial.
    Erfanian SS; Ansari H; Javanmard SH; Amini Z; Hajigholami A · BMC complementary medicine and therapies · 2024
    Randomized trial100 participantsDetoxification forMilk Thistle
  9. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  10. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  11. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle