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Liver 21 Day Cleanse

Dr. Tobias
4.3
★ ★ ★ ★ ★
(5023 ratings)
Milk Thistle 150 mg
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Score81

A short-term 21-day liver cleanse formula featuring botanicals and digestive enzymes for metabolic support.

How scoring works
Quantity:63 Capsule(s) • (21 servings)
Goals:
Detoxification

Score 81

A short-term 21-day liver cleanse formula featuring botanicals and digestive enzymes for metabolic support.

How scoring works
$27.02($1.28 per serving)
iHerb
$ 27.02
Amazon
$ 47.99
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Analysis

This supplement features a blend of botanicals and enzymes to support the liver's natural detoxification pathways over three weeks. Dandelion and artichoke are included to help with waste removal, while enzymes like lipase assist with nutrient breakdown. The formula aims to provide a comprehensive temporary support system for the body's clearance organs.

While the combination is interesting, the milk thistle is not standardized to silymarin, which makes its exact potency harder to determine. It is best used as a temporary addition to a wellness routine rather than a permanent supplement. The 21-day format is convenient for those who prefer structured cleansing cycles.

Pros

  • Includes enzymes like lipase and protease
  • Contains artichoke and dandelion extracts
  • Convenient 21-day supply

Cons

  • Milk thistle is not standardized to silymarin
  • Relatively expensive for 3 weeks of use
  • Lower transparency on enzyme activity levels

Warnings

  • Consult a professional for repeated use
  • Monitor for enzyme-related digestive changes

Nutrient quality

81 Highest impact

The inclusion of Solarplast and enzymes offers a unique approach to liver and digestive support. However, the lack of standardization for the milk thistle and artichoke extracts is a significant drawback for assessing potency.

Ingredient transparency

86 Highest impact

Most active ingredients are quantified by weight, but the formula lacks details on silymarin or cynarin standardization. Enzyme activity units are also missing, which makes the efficacy of the digestive support harder to evaluate.

Customer satisfaction

86 Highest impact

The product has a large following but a lower average rating than simple milk thistle extracts. Reviews are mixed, with some users reporting positive cleanse results and others seeing little change.

Value for money

71 High impact

The cost per serving is significantly higher than daily liver support options due to its positioning as a short-term cleanse. While it contains diverse ingredients, the overall value is lower for those seeking long-term maintenance.

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Goals

Detoxification
Impact
High effect
B Goal FitD+ Strength of SupportB- CoverageA- Formula Quality

This short-term cleanse includes milk thistle and artichoke to support liver protection and metabolic clearance. Dandelion leaf extract further contributes to the body's natural drainage and waste removal processes.

While the formula targets multiple liver pathways, the lack of silymarin standardization reduces confidence in the clinical impact. Inclusion of digestive enzymes provides secondary support for overall metabolic health and nutrient uptake.

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Ingredients

IngredientAmount per serving
Solarplast (Chloroplast)
 300 mg
Artichoke leaf extract
225 mg
Dandelion Leaf Extract
150 mg
Milk Thistle Seed Extract
150 mg
Protease SP (Aspergillus oryzae, Bacillus subtilis)
 0 NP
Lipase (Candida rugosa)
 0 NP
Adults 18–50
Report overview
Milk Thistle · 150 mg OverallScore24
D- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value
Designed as a short-term cleanse, this product includes milk thistle and artichoke combined with digestive enzymes. However, the lack of silymarin standardization and a determined active dose makes its effectiveness for liver protection uncertain.
View ingredientView products
94 Value

Detox Support

Zoi Research
4.7
★★★★★
(3163 ratings)
Standardized silymarin with Kutki root and an absorption blend provides a more reliable impact on healthy hepatic function. This formula assists in maintaining metabolic clearance for a more competitive price.
Other sellers (0)
93 Value

Milk Thistle Phytosome 150 mg

Natural Factors HerbalFactors
4.7
★★★★★
(343 ratings)
Highly absorbable phytosome form of silymarin along with a blend of supportive botanicals ensures a more efficient cleanse. Dandelion and artichoke contribute to healthy bile flow and broader hepatic support.
Other sellers (3)
95 Value

Extra Strength Silymarin

NOW
4.8
★★★★★
(7353 ratings)
Potent 450 mg dose of silymarin flavonoids focuses on the most researched liver-supporting ingredient for the best price. This softgel format aids in the absorption of active fat-soluble botanical compounds.
Other sellers (6)
89 Performance

Super Thisilyn

Nature's Way
4.6
★★★★★
(610 ratings)
Sophisticated blend of NAC, alpha-lipoic acid, and standardized turmeric supports both Phase I and II detoxification. This formula provides a reliable 175 mg dose of silymarin aligned with liver protection goals.
Other sellers (4)
95 Performance

Super Milk Thistle

Nature's Way
4.7
★★★★★
(333 ratings)
Standardized silybin and caffeoylquinic acids ensure consistent and powerful support for hepatic pathways and biliary flow. Synergistic herb-extract combinations provide a professional grade approach to liver care.
Other sellers (4)
94 Performance

Advanced Milk Thistle

Life Extension
4.6
★★★★★
(8074 ratings)
Phytosome technology ensures primary active compounds like silybin are absorbed and utilized with high efficiency. Phospholipid complexes contribute to improved intestinal uptake compared to standard extracts.
Other sellers (5)
96 Budget

Silymarin Complex

California Gold Nutrition
4.8
★★★★★
(77883 ratings)
Includes standardized silymarin, dandelion, and artichoke at a significantly more accessible price per serving. These botanical extracts contribute to liver cell protection and natural detoxification processes.
Other sellers (0)
94 Budget

Liver Essentials

Swanson
4.8
★★★★★
(956 ratings)
Standardized silymarin and NAC provide better clinical support for detoxification pathways at a lower cost. Meaningful levels of supportive herbs assist in the natural removal of metabolic waste.
Other sellers (2)
89 Budget

Milk Thistle 250 mg

Natural Factors HerbalFactors
4.7
★★★★★
(2593 ratings)
Combines milk thistle with turmeric and dandelion root for effective biliary and metabolic support at a budget price. Concentrated silymarin helps maintain hepatocyte integrity during environmental stress.
Other sellers (2)
94 Value

Detox Support

Zoi Research
4.7
★★★★★
(3163 ratings)
Standardized silymarin with Kutki root and an absorption blend provides a more reliable impact on healthy hepatic function. This formula assists in maintaining metabolic clearance for a more competitive price.
Other sellers (0)
93 Value

Milk Thistle Phytosome 150 mg

Natural Factors HerbalFactors
4.7
★★★★★
(343 ratings)
Highly absorbable phytosome form of silymarin along with a blend of supportive botanicals ensures a more efficient cleanse. Dandelion and artichoke contribute to healthy bile flow and broader hepatic support.
Other sellers (3)
95 Value

Extra Strength Silymarin

NOW
4.8
★★★★★
(7353 ratings)
Potent 450 mg dose of silymarin flavonoids focuses on the most researched liver-supporting ingredient for the best price. This softgel format aids in the absorption of active fat-soluble botanical compounds.
Other sellers (6)
89 Performance

Super Thisilyn

Nature's Way
4.6
★★★★★
(610 ratings)
Sophisticated blend of NAC, alpha-lipoic acid, and standardized turmeric supports both Phase I and II detoxification. This formula provides a reliable 175 mg dose of silymarin aligned with liver protection goals.
Other sellers (4)
95 Performance

Super Milk Thistle

Nature's Way
4.7
★★★★★
(333 ratings)
Standardized silybin and caffeoylquinic acids ensure consistent and powerful support for hepatic pathways and biliary flow. Synergistic herb-extract combinations provide a professional grade approach to liver care.
Other sellers (4)
94 Performance

Advanced Milk Thistle

Life Extension
4.6
★★★★★
(8074 ratings)
Phytosome technology ensures primary active compounds like silybin are absorbed and utilized with high efficiency. Phospholipid complexes contribute to improved intestinal uptake compared to standard extracts.
Other sellers (5)
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