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Detox Daily Liver Support

4.8
★ ★ ★ ★ ★
(8243 ratings)
Milk Thistle 350 mg
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Score51
A focused botanical idea is undermined by two undisclosed blends. Missing silymarin potency and hidden absorption ingredients make the formula hard to assess.
How scoring works
Capsule
Quantity:120 Capsule(s) • (60 servings)
Goals:
Detoxification

Score 51

A focused botanical idea is undermined by two undisclosed blends. Missing silymarin potency and hidden absorption ingredients make the formula hard to assess.
How scoring works
$26.97($0.44 per serving)
Vitacost
$ 28.93
iHerb
$ 30.45
Amazon
$ 26.97
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Analysis

The visible actives include 350 mg milk thistle seed extract and 200 mg picrorhiza extract. Those ingredients provide a more focused base than a generic mixture of unrelated herbs.

A 300 mg proprietary compound and 23 mg absorption blend do not disclose their constituents or individual amounts. Milk thistle also lacks a stated silymarin percentage, so even the main active remains only partly characterized.

Two capsules provide sixty servings, but opacity is the main purchasing drawback. A formula with fully disclosed supporting ingredients would be easier to use safely.

Who is it for
  • Adults who can verify all proprietary blend ingredients on the label
  • People specifically seeking milk thistle with picrorhiza
  • Users prepared to review interactions carefully
Best for
  • Milk thistle and picrorhiza combination
  • Short-term use after full label review
  • Users comfortable with proprietary blends

Pros

  • Milk thistle extract amount is disclosed
  • Picrorhiza amount is listed
  • Sixty servings
  • Two-capsule serving

Cons

  • Two proprietary blends
  • No silymarin standardization
  • Hidden ingredients block interaction review
  • Weak transparency
  • Potency is difficult to compare

Warnings

  • Picrorhiza may be unsuitable for people with bile-duct obstruction or symptomatic gallstones.
  • Undisclosed blend ingredients prevent a reliable check for allergens and medication interactions.
  • Milk thistle may cause reactions in people sensitive to ragweed-family plants.

Nutrient quality

51 Moderate impact

The named botanicals give the formula a relevant liver-support foundation. Unstandardized extracts and two opaque blends undermine dose quality and coherence.

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Ingredient transparency

42 Lower impact

Named botanicals and blend totals provide partial label detail. Hidden components, vague names, incomplete directions, and absent excipients severely limit transparency.

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Customer satisfaction

71 High impact

The aggregate satisfaction signal is favorable and has some support from the supplied volume. Specific experience details are absent, so complaint patterns and purpose fit cannot be confirmed.

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Value for money

43 Lower impact

Relevant named botanicals provide a basic value foundation. Opaque blends and uncertain potency make effective serving value difficult to justify.

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Report analysis

Goals

Detoxification
Detoxification
Impact
Moderate effect
B Goal FitF Strength of SupportC- CoverageD+ Formula Quality
Milk Thistle · 350 mg

Milk thistle and picrorhiza give the formula a direct liver-support focus. The milk thistle extract weight is clear, but no silymarin percentage or active amount is provided.

A 300 mg proprietary hepatoprotective blend and a second proprietary accelerator blend conceal important ingredient identities and doses. Missing standardization and dry-capsule delivery make the apparent breadth difficult to translate into dependable potency.

Study evidence
Milk Thistle Supportive 46 studies

Ingredients

IngredientAmount per serving
Milk Thistle Seed Extract
350 mg
Picrorhiza kurroa extract
200 mg
Proprietary Hepatoprotective Compound
300 mg
Futurebiotics BioAccelerators
23 mg
Adults 18–50 Women Vegetarian
Report overview
Milk Thistle · 350 mg OverallScore17
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

Seed-derived milk thistle extract provides a relevant plant source with its amount clearly disclosed. The missing silymarin standardization prevents confirmation of active potency, while the dry capsule lacks a defined absorption-enhancing system. Its cost sits above the collection median without evidence of standardized or premium milk thistle quality.

View ingredientView products
Loading alternative details
84 Performance

Milk Thistle

Kroeger Herb Products Co.
<p>A separate silymarin amount from milk thistle seed makes potency unusually easy to assess. The clearer active profile or delivery form makes potency easier to judge than in the original, though any broader companion-ingredient role may be lost.</p>
82 Performance

Super Milk Thistle

Nature's Way
<p>Well-disclosed silymarin and silybin amounts form a strong milk thistle core, with artichoke adding relevant bile support. The clearer active profile or delivery form makes potency easier to judge than in the original, though any broader companion-ingredient role may be lost.</p>
86 Performance

Milk Thistle Extract 175 mg

Lake Avenue Nutrition
<p>A meaningful total silymarin amount from milk thistle seed makes potency straightforward to assess. The clearer active profile or delivery form makes potency easier to judge than in the original, though any broader companion-ingredient role may be lost.</p>
87 Budget

Milk Thistle Extract 175 mg

Lake Avenue Nutrition
<p>A meaningful total silymarin amount from milk thistle seed makes potency straightforward to assess. It costs less per serving than the original, while differences in extract amount, delivery format, or companion herbs should guide the final choice.</p>
80 Budget

Silymarin Complex

California Gold Nutrition
<p>Milk thistle anchors a coherent liver-support combination with dandelion, artichoke, turmeric, ginger, and black pepper. It costs less per serving than the original, while differences in extract amount, delivery format, or companion herbs should guide the final choice.</p>
78 Budget

Milk Thistle 30:1 Extract

Jarrow Formulas
<p>A concentrated single-ingredient extract provides focused liver-support value at a very accessible serving cost. It costs less per serving than the original, while differences in extract amount, delivery format, or companion herbs should guide the final choice.</p>
85 Value

Milk Thistle

Paradise
<p>A substantial stated silymarin amount provides focused milk thistle potency in a simple formula. The balance of disclosed milk-thistle quality and serving economy offers a favorable value trade-off, with formula breadth and delivery form remaining practical differences.</p>
84 Value

Milk Thistle

Nature's Answer
<p>A meaningful stated silymarin amount is paired with a small whole-herb component in a focused formula. The balance of disclosed milk-thistle quality and serving economy offers a favorable value trade-off, with formula breadth and delivery form remaining practical differences.</p>
79 Value

Milk Thistle

Solgar
<p>A standardized extract paired with whole milk thistle powder gives the formula a sensible, focused structure. The balance of disclosed milk-thistle quality and serving economy offers a favorable value trade-off, with formula breadth and delivery form remaining practical differences.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury.
    Shahsavari K; Ardekani SS; Ardekani MRS; Esfahani MM; Kazemizadeh H; Jamialahmadi T; Iranshahi M; Khanavi M; Hasanpour M · BMC complementary medicine and therapies · 2025
    Meta-analysis3,545 participants55 studies pooledDetoxification forMilk Thistle
  2. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle
  3. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  4. A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury.
    Luangchosiri C; Thakkinstian A; Chitphuk S; Stitchantrakul W; Petraksa S; Sobhonslidsuk A · BMC complementary and alternative medicine · 2016
    Randomized trial55 participantsDetoxification forMilk Thistle
  5. Effect of 8 Weeks milk thistle powder (silymarin extract) supplementation on fatty liver disease in patients candidates for bariatric surgery.
    Mirhashemi SH; Hakakzadeh A; Yeganeh FE; Oshidari B; Rezaee SP · Metabolism open · 2022
    Observational studyDetoxification forMilk Thistle
  6. A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis.
    El-Kamary SS; Shardell MD; Abdel-Hamid M; Ismail S; El-Ateek M; Metwally M; Mikhail N; Hashem M; Mousa A; Aboul-Fotouh A; El-Kassas M; Esmat G; Strickland GT · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2009
    Randomized trial105 participantsDetoxification forMilk Thistle
  7. Evaluation of Hepatoprotective Effect of Silymarin Among Under Treatment Tuberculosis Patients: A Randomized Clinical Trial.
    Marjani M; Baghaei P; Kazempour Dizaji M; Gorji Bayani P; Fahimi F; Tabarsi P; Velayati AA · Iranian journal of pharmaceutical research : IJPR · 2016
    Randomized trial70 participantsDetoxification forMilk Thistle
  8. The hepatorenal protective effects of silymarin in cancer patients receiving chemotherapy: a randomized, placebo-controlled trial.
    Erfanian SS; Ansari H; Javanmard SH; Amini Z; Hajigholami A · BMC complementary medicine and therapies · 2024
    Randomized trial100 participantsDetoxification forMilk Thistle
  9. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  10. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  11. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle