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Milk Thistle

4.7
★ ★ ★ ★ ★
(2752 ratings)
Milk Thistle 175 mg
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Score73
A long-supply milk thistle capsule with a useful extract amount. Blessed thistle and missing silymarin standardization keep it from standing out.
How scoring works
Capsule
Quantity:120 Capsule(s) • (120 servings)
Goals:
Detoxification

Score 73

A long-supply milk thistle capsule with a useful extract amount. Blessed thistle and missing silymarin standardization keep it from standing out.
How scoring works
$35.44($0.29 per serving)
iHerb
$ 36.49
Vitacost
$ 36.49
Amazon
$ 35.44
Vitacost
$ 36.49
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Analysis

Milk thistle seed extract is listed at 175 mg and identified as silymarin. The bottle provides a long supply at one capsule per serving.

Blessed thistle adds 120 mg but has a less direct role in the intended use. The silymarin percentage is absent, so active potency cannot be verified from the extract weight.

One hundred twenty servings suit users who want a consistent routine. A simpler standardized silymarin capsule may offer clearer value.

Who is it for
  • Adults wanting many milk thistle servings
  • People comfortable with blessed thistle
  • Users who prefer one capsule per day
Best for
  • Long-term serving convenience
  • Basic milk thistle use
  • Two-botanical supplementation

Pros

  • 175 mg milk thistle extract
  • Seed source is identified
  • Silymarin is named
  • One hundred twenty servings

Cons

  • Silymarin percentage is missing
  • Blessed thistle has limited added value
  • No absorption support
  • Less focused than single-active products

Warnings

  • Both botanicals may trigger reactions in people sensitive to ragweed-family plants.
  • Discontinue use if persistent digestive discomfort occurs.

Nutrient quality

66 High impact

The relevant seed extract provides a plausible core for liver support. Unknown silymarin potency and a weaker secondary herb limit quality.

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Ingredient transparency

80 High impact

All listed actives have amounts and no hidden blend is present. Standardization, usage instructions, and excipient disclosure remain incomplete.

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Customer satisfaction

69 High impact

The aggregate satisfaction signal is favorable and has some support from the supplied volume. Specific experience details are absent, so complaint patterns and purpose fit cannot be confirmed.

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Value for money

77 High impact

A long supply and accessible serving value support routine use. Missing active-yield detail and a weaker add-on constrain the quality case.

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Report analysis

Goals

Detoxification
Impact
High effect
B+ Goal FitC Strength of SupportD+ CoverageB+ Formula Quality
Milk Thistle · 175 mg

Silymarin-containing milk thistle provides the main liver-protection and antioxidant function. Blessed thistle broadens the digestive theme but contributes less direct evidence for metabolic clearance.

The formula is compact and avoids unrelated actives, yet the silymarin percentage is missing. Active potency therefore remains uncertain even though the milk thistle extract amount appears plausible.

Study evidence
Milk Thistle Supportive 46 studies

Ingredients

IngredientAmount per serving
Milk Thistle seed extract (Silymarin)
175 mg
Blessed Thistle
120 mg
Gluten Free Adults 18–50 Vegan Dairy Free Sugar Free Vegetarian
Report overview
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyB- Value

The seed-derived extract provides a clearly identified source, but no silymarin percentage or active amount is given. Its standard capsule format offers no stated absorption support. The serving cost is low, although the unknown effective dose limits confidence.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury.
    Shahsavari K; Ardekani SS; Ardekani MRS; Esfahani MM; Kazemizadeh H; Jamialahmadi T; Iranshahi M; Khanavi M; Hasanpour M · BMC complementary medicine and therapies · 2025
    Meta-analysis3,545 participants55 studies pooledDetoxification forMilk Thistle
  2. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle
  3. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  4. A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury.
    Luangchosiri C; Thakkinstian A; Chitphuk S; Stitchantrakul W; Petraksa S; Sobhonslidsuk A · BMC complementary and alternative medicine · 2016
    Randomized trial55 participantsDetoxification forMilk Thistle
  5. Effect of 8 Weeks milk thistle powder (silymarin extract) supplementation on fatty liver disease in patients candidates for bariatric surgery.
    Mirhashemi SH; Hakakzadeh A; Yeganeh FE; Oshidari B; Rezaee SP · Metabolism open · 2022
    Observational studyDetoxification forMilk Thistle
  6. A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis.
    El-Kamary SS; Shardell MD; Abdel-Hamid M; Ismail S; El-Ateek M; Metwally M; Mikhail N; Hashem M; Mousa A; Aboul-Fotouh A; El-Kassas M; Esmat G; Strickland GT · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2009
    Randomized trial105 participantsDetoxification forMilk Thistle
  7. Evaluation of Hepatoprotective Effect of Silymarin Among Under Treatment Tuberculosis Patients: A Randomized Clinical Trial.
    Marjani M; Baghaei P; Kazempour Dizaji M; Gorji Bayani P; Fahimi F; Tabarsi P; Velayati AA · Iranian journal of pharmaceutical research : IJPR · 2016
    Randomized trial70 participantsDetoxification forMilk Thistle
  8. The hepatorenal protective effects of silymarin in cancer patients receiving chemotherapy: a randomized, placebo-controlled trial.
    Erfanian SS; Ansari H; Javanmard SH; Amini Z; Hajigholami A · BMC complementary medicine and therapies · 2024
    Randomized trial100 participantsDetoxification forMilk Thistle
  9. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  10. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  11. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle