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Milk Thistle 450 mg

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(572 ratings)
Milk Thistle 175 mg
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Score74
Useful milk thistle extract is mixed with a larger amount of whole-herb powder. Good convenience cannot fully offset unclear active silymarin potency.
How scoring works
Capsule
Quantity:60 Capsule(s) • (60 servings)
Goals:
Detoxification

Score 74

Useful milk thistle extract is mixed with a larger amount of whole-herb powder. Good convenience cannot fully offset unclear active silymarin potency.
How scoring works
$16.49($0.27 per serving)
Vitacost
$ 16.49
iHerb
$ 16.49
Amazon
$ 16.49
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Analysis

The serving combines 175 mg milk thistle extract identified as silymarin with 275 mg milk thistle powder. That gives a direct extract component plus a larger amount of less concentrated plant material.

The extract is the meaningful part, but no silymarin percentage or active yield is provided. Calling the product 450 mg can therefore overstate how much standardized material it delivers.

Sixty single-capsule servings make it convenient for routine use. It fits basic milk thistle support better than users seeking the most transparent high-potency extract.

Who is it for
  • Adults seeking a mixed extract-and-herb capsule
  • People who want one capsule per serving
  • Users prioritizing reasonable serving value
Best for
  • Routine milk thistle use
  • A blend of extract and whole herb
  • Simple daily dosing

Pros

  • 175 mg extract is disclosed
  • Silymarin is named
  • Whole-herb amount is separate
  • Sixty servings

Cons

  • Silymarin percentage is missing
  • Whole powder is less concentrated
  • Total front-label weight can obscure active potency
  • No absorption feature is listed

Warnings

  • Milk thistle may trigger a reaction in people sensitive to ragweed-family plants.
  • Digestive upset is possible in sensitive users.

Nutrient quality

71 High impact

The substantial extract-and-powder combination is well aligned with liver support. Unknown standardization prevents confirmation of the active dose.

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Ingredient transparency

78 High impact

Each active has a stated amount without a hidden blend. Standardization, full directions, and inactive ingredients are not provided.

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Customer satisfaction

64 Moderate impact

The aggregate satisfaction signal is favorable and has some support from the supplied volume. Specific experience details are absent, so complaint patterns and purpose fit cannot be confirmed.

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Value for money

83 Highest impact

A substantial serving and low daily cost make the product competitively positioned. Missing active-yield detail prevents full confidence in effective value.

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Goals

Detoxification
Detoxification
Impact
High effect
B+ Goal FitC Strength of SupportD CoverageA Formula Quality
Milk Thistle · 275 mg

Milk thistle provides focused liver-cell and antioxidant support through an extract plus whole-herb powder. The combined material is substantial, but the amount of active silymarin cannot be confirmed from the label details.

A single-pathway design keeps the formula simple and avoids unrelated ingredients. Missing extract standardization limits confidence that the labeled weight delivers a reliably effective active amount.

Study evidence
Milk Thistle Supportive 46 studies

Ingredients

IngredientAmount per serving
Milk Thistle extract (Silymarin)
 175 mg
Milk Thistle powder
275 mg
Adults 18–50 Dairy Free
Report overview
Milk Thistle (Silymarin) · 175 mg OverallScore24
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyB- Value

The formula combines an extract with seed powder, but it does not disclose a silymarin percentage or active amount. Its dry capsule format provides no stated absorption support. The low serving cost helps, although uncertain potency limits confidence in the value.

View ingredientView products
Loading alternative details
84 Performance

Milk Thistle

Kroeger Herb Products Co.
<p>A separate silymarin amount from milk thistle seed makes potency unusually easy to assess. The clearer active profile or delivery form makes potency easier to judge than in the original, though any broader companion-ingredient role may be lost.</p>
82 Performance

Super Milk Thistle

Nature's Way
<p>Well-disclosed silymarin and silybin amounts form a strong milk thistle core, with artichoke adding relevant bile support. The clearer active profile or delivery form makes potency easier to judge than in the original, though any broader companion-ingredient role may be lost.</p>
86 Performance

Milk Thistle Extract 175 mg

Lake Avenue Nutrition
<p>A meaningful total silymarin amount from milk thistle seed makes potency straightforward to assess. The clearer active profile or delivery form makes potency easier to judge than in the original, though any broader companion-ingredient role may be lost.</p>
87 Budget

Milk Thistle Extract 175 mg

Lake Avenue Nutrition
<p>A meaningful total silymarin amount from milk thistle seed makes potency straightforward to assess. It costs less per serving than the original, while differences in extract amount, delivery format, or companion herbs should guide the final choice.</p>
80 Budget

Silymarin Complex

California Gold Nutrition
<p>Milk thistle anchors a coherent liver-support combination with dandelion, artichoke, turmeric, ginger, and black pepper. It costs less per serving than the original, while differences in extract amount, delivery format, or companion herbs should guide the final choice.</p>
78 Budget

Milk Thistle 30:1 Extract

Jarrow Formulas
<p>A concentrated single-ingredient extract provides focused liver-support value at a very accessible serving cost. It costs less per serving than the original, while differences in extract amount, delivery format, or companion herbs should guide the final choice.</p>
85 Value

Milk Thistle

Paradise
<p>A substantial stated silymarin amount provides focused milk thistle potency in a simple formula. The balance of disclosed milk-thistle quality and serving economy offers a favorable value trade-off, with formula breadth and delivery form remaining practical differences.</p>
84 Value

Milk Thistle

Nature's Answer
<p>A meaningful stated silymarin amount is paired with a small whole-herb component in a focused formula. The balance of disclosed milk-thistle quality and serving economy offers a favorable value trade-off, with formula breadth and delivery form remaining practical differences.</p>
79 Value

Milk Thistle

Solgar
<p>A standardized extract paired with whole milk thistle powder gives the formula a sensible, focused structure. The balance of disclosed milk-thistle quality and serving economy offers a favorable value trade-off, with formula breadth and delivery form remaining practical differences.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  2. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  3. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  4. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle
  5. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle