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Milk Thistle Seed Extract 350 mg

4.7
★ ★ ★ ★ ★
(1220 ratings)
Milk Thistle 350 mg
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Score70
A large milk thistle extract amount with a smaller whole-herb addition. Missing silymarin percentage and middling value hold it back.
How scoring works
Capsule
Quantity:60 VegCap(s) • (60 servings)
Goals:
Detoxification

Score 70

A large milk thistle extract amount with a smaller whole-herb addition. Missing silymarin percentage and middling value hold it back.
How scoring works
$30.67($0.51 per serving)
Vitacost
$ 35.09
iHerb
$ 35.09
Amazon
$ 30.67
Pure Formulas
$ 35.09
iHerb
$ 35.09
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Analysis

The capsule combines 350 mg milk thistle seed extract identified as silymarin with 110 mg whole milk thistle. The seed source and separate amounts improve clarity.

Active potency still cannot be confirmed because the silymarin percentage is absent. The added whole herb broadens total weight without matching the concentration of an extract.

Sixty one-capsule servings are convenient, but serving value is only moderate. It suits users who want a higher extract weight and do not require exact active yield.

Who is it for
  • Adults seeking a higher-weight milk thistle extract
  • People who value seed-source disclosure
  • Users comfortable with a mixed extract-and-herb capsule
Best for
  • Higher-weight milk thistle use
  • Single-capsule dosing
  • Extract plus whole-herb supplementation

Pros

  • 350 mg extract amount
  • Seed source is named
  • Silymarin is identified
  • Whole-herb amount is separate
  • Sixty servings

Cons

  • No silymarin percentage
  • Whole herb is less concentrated
  • No absorption support
  • Value trails simpler options

Warnings

  • Milk thistle may cause reactions in people sensitive to ragweed-family plants.
  • Digestive upset may occur in sensitive users.

Nutrient quality

72 High impact

The seed extract and whole herb create meaningful milk thistle depth. Missing standardization prevents confirmation of active potency and delivery quality.

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Ingredient transparency

80 High impact

Amounts and source details are mostly clear without a hidden blend. Standardization, intake directions, and excipient disclosure are incomplete.

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Customer satisfaction

68 High impact

The aggregate satisfaction signal is favorable and has some support from the supplied volume. Specific experience details are absent, so complaint patterns and purpose fit cannot be confirmed.

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Value for money

58 Moderate impact

Substantial milk thistle weight provides some formula value. Premium serving positioning is hard to justify without a verified active yield.

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Report analysis

Goals

Detoxification
Detoxification
Impact
Moderate effect
B+ Goal FitD- Strength of SupportD- CoverageB Formula Quality
Milk Thistle · 110 mg

Milk thistle has a direct liver-protective and antioxidant role that fits ongoing detoxification support. The seed source and extract weight are clear, but the label does not state a silymarin percentage or active amount.

Without standardization, the practical dose and expected potency cannot be confirmed, and the dry capsule has no absorption-enhancing system. The extra milk thistle powder broadens the plant weight but does not solve the missing active-compound disclosure.

Study evidence
Milk Thistle Supportive 46 studies

Ingredients

IngredientAmount per serving
Milk Thistle seed extract (Silymarin)
 350 mg
Milk Thistle
110 mg
Adults 18–50
Report overview
Milk Thistle (Silymarin) · 350 mg OverallScore18
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

The seed-derived extract is clearly sourced, but the label does not state a silymarin percentage or active amount. The dry capsule offers no specified absorption enhancement. A higher serving cost is hard to justify without verified standardization or effective potency.

View ingredientView products
Loading alternative details
84 Performance

Milk Thistle

Kroeger Herb Products Co.
<p>A separate silymarin amount from milk thistle seed makes potency unusually easy to assess. The clearer active profile or delivery form makes potency easier to judge than in the original, though any broader companion-ingredient role may be lost.</p>
82 Performance

Super Milk Thistle

Nature's Way
<p>Well-disclosed silymarin and silybin amounts form a strong milk thistle core, with artichoke adding relevant bile support. The clearer active profile or delivery form makes potency easier to judge than in the original, though any broader companion-ingredient role may be lost.</p>
86 Performance

Milk Thistle Extract 175 mg

Lake Avenue Nutrition
<p>A meaningful total silymarin amount from milk thistle seed makes potency straightforward to assess. The clearer active profile or delivery form makes potency easier to judge than in the original, though any broader companion-ingredient role may be lost.</p>
87 Budget

Milk Thistle Extract 175 mg

Lake Avenue Nutrition
<p>A meaningful total silymarin amount from milk thistle seed makes potency straightforward to assess. It costs less per serving than the original, while differences in extract amount, delivery format, or companion herbs should guide the final choice.</p>
80 Budget

Silymarin Complex

California Gold Nutrition
<p>Milk thistle anchors a coherent liver-support combination with dandelion, artichoke, turmeric, ginger, and black pepper. It costs less per serving than the original, while differences in extract amount, delivery format, or companion herbs should guide the final choice.</p>
78 Budget

Milk Thistle 30:1 Extract

Jarrow Formulas
<p>A concentrated single-ingredient extract provides focused liver-support value at a very accessible serving cost. It costs less per serving than the original, while differences in extract amount, delivery format, or companion herbs should guide the final choice.</p>
85 Value

Milk Thistle

Paradise
<p>A substantial stated silymarin amount provides focused milk thistle potency in a simple formula. The balance of disclosed milk-thistle quality and serving economy offers a favorable value trade-off, with formula breadth and delivery form remaining practical differences.</p>
84 Value

Milk Thistle

Nature's Answer
<p>A meaningful stated silymarin amount is paired with a small whole-herb component in a focused formula. The balance of disclosed milk-thistle quality and serving economy offers a favorable value trade-off, with formula breadth and delivery form remaining practical differences.</p>
79 Value

Milk Thistle

Solgar
<p>A standardized extract paired with whole milk thistle powder gives the formula a sensible, focused structure. The balance of disclosed milk-thistle quality and serving economy offers a favorable value trade-off, with formula breadth and delivery form remaining practical differences.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  2. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  3. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  4. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle
  5. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle