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Milk Thistle & Cranberry

4.7
★ ★ ★ ★ ★
(769 ratings)
Milk Thistle 150 mg
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Score65
A clear two-herb label combines liver and urinary support, but cranberry-heavy dosing weakens its milk thistle focus.
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Capsule
Quantity:60 Capsule(s) • (30 servings)
Goals:

Score 65

A clear two-herb label combines liver and urinary support, but cranberry-heavy dosing weakens its milk thistle focus.
How scoring works
$9.86($0.32 per serving)
iHerb
$ 9.86
Pure Formulas
$ 10.79
Amazon
$ 12.49
Vitacost
$ 10.49
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Analysis

The milk thistle extract provides a direct liver antioxidant component, while cranberry adds a separate urinary-tract focus. The two ingredients are clearly listed without a proprietary blend.

Cranberry accounts for most of the active weight, so the formula is not optimized around milk thistle. The label names silymarin but does not provide its concentration or actual active yield.

The combination may suit someone who independently wants both botanicals and prefers one capsule product. A dedicated standardized milk thistle extract is a better fit for focused liver support.

Who is it for
  • Adults who want both cranberry and milk thistle
  • People seeking a simple two-botanical blend
  • Users with mixed liver and urinary-support priorities
Best for
  • Combining two separate botanical routines
  • General antioxidant support
  • People who value a concise ingredient list

Pros

  • Exact botanical weights are shown
  • No proprietary blend
  • Cranberry adds a distinct use case

Cons

  • Cranberry dominates the formula
  • Milk thistle potency is unverified
  • The two ingredients have limited shared purpose

Warnings

  • Cranberry may increase bleeding risk with warfarin; users of vitamin K antagonists should ask their prescriber before use.
  • Milk thistle may cause nausea, gas, or loose stools in sensitive users.
  • People allergic to ragweed, daisies, or related plants may react to milk thistle.

Nutrient quality

55 Moderate impact

The modest milk thistle extract provides relevant but uncertain active support. A much larger cranberry dose acts as low-value padding for the intended use.

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Ingredient transparency

79 High impact

Individual botanical amounts and the absence of a blend make the formula easy to follow. Milk thistle standardization, usage, and excipient details remain missing.

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Customer satisfaction

70 High impact

The average rating is positive, and the available feedback volume provides useful confidence. No specific experience details are supplied to assess recurring complaints or purpose fit.

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Value for money

51 Moderate impact

Low serving cost provides some practical affordability. A dominant, less relevant cranberry dose makes effective liver-support value weak.

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Ingredients

IngredientAmount per serving
Cranberry Whole Fruit Extract
500 mg
Milk Thistle extract (Silymarin)
150 mg
Gluten Free Adults 18–50
Report overview
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyD- Value

The milk thistle extract names silymarin but does not disclose its concentration or active yield. Its dry capsules provide no special absorption support, and the milk thistle plant part is unclear. The low serving cost is attractive, but confirmed potency is missing.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury.
    Shahsavari K; Ardekani SS; Ardekani MRS; Esfahani MM; Kazemizadeh H; Jamialahmadi T; Iranshahi M; Khanavi M; Hasanpour M · BMC complementary medicine and therapies · 2025
    Meta-analysis3,545 participants55 studies pooledDetoxification forMilk Thistle
  2. Evaluation of Hepatoprotective Effect of Silymarin Among Under Treatment Tuberculosis Patients: A Randomized Clinical Trial.
    Marjani M; Baghaei P; Kazempour Dizaji M; Gorji Bayani P; Fahimi F; Tabarsi P; Velayati AA · Iranian journal of pharmaceutical research : IJPR · 2016
    Randomized trial70 participantsDetoxification forMilk Thistle
  3. Effect of 8 Weeks milk thistle powder (silymarin extract) supplementation on fatty liver disease in patients candidates for bariatric surgery.
    Mirhashemi SH; Hakakzadeh A; Yeganeh FE; Oshidari B; Rezaee SP · Metabolism open · 2022
    Observational studyDetoxification forMilk Thistle
  4. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  5. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle
  6. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  7. The hepatorenal protective effects of silymarin in cancer patients receiving chemotherapy: a randomized, placebo-controlled trial.
    Erfanian SS; Ansari H; Javanmard SH; Amini Z; Hajigholami A · BMC complementary medicine and therapies · 2024
    Randomized trial100 participantsDetoxification forMilk Thistle
  8. A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury.
    Luangchosiri C; Thakkinstian A; Chitphuk S; Stitchantrakul W; Petraksa S; Sobhonslidsuk A · BMC complementary and alternative medicine · 2016
    Randomized trial55 participantsDetoxification forMilk Thistle
  9. A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis.
    El-Kamary SS; Shardell MD; Abdel-Hamid M; Ismail S; El-Ateek M; Metwally M; Mikhail N; Hashem M; Mousa A; Aboul-Fotouh A; El-Kassas M; Esmat G; Strickland GT · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2009
    Randomized trial105 participantsDetoxification forMilk Thistle
  10. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle