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Double Strength Silymarin

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4.8
★ ★ ★ ★ ★
(134052 ratings)
Milk Thistle 300 mg
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Score76
Useful botanical breadth and low ongoing cost are offset by missing standardization across all three extracts.
How scoring works
Quantity:200 Capsule(s) • (200 servings)
Goals:
Detoxification

Score 76

Useful botanical breadth and low ongoing cost are offset by missing standardization across all three extracts.
How scoring works

Also available as

2 options
100 servings Milk Thistle 300 mg • 100 Capsule(s) • 100 servings $17.20 ($0.17 per serving) 50 servings Milk Thistle 300 mg • 50 Capsule(s) • 50 servings $9.22 ($0.18 per serving)
$25.04($0.12 per serving)
Vitacost
$ 28.19
iHerb
$ 26.24
Daily Vita
$ 28.90
Amazon
$ 25.04
iHerb
$ 26.24
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Analysis

The milk thistle amount forms the core of the formula, while dandelion and artichoke broaden its botanical coverage. The combination is more purposeful than adding unrelated vitamins or filler ingredients.

No silymarin percentage or active markers for the supporting botanicals are disclosed. Their smaller weights may provide only modest depth, and the dry capsule offers no stated absorption feature.

A long supply and very low serving cost make the blend easy to use regularly. It fits value seekers who want botanical breadth more than precisely verified potency.

Who is it for
  • Adults seeking a broad liver-and-digestion blend
  • Budget-focused long-term users
  • People who prefer multi-herb capsules
Best for
  • Combining milk thistle, dandelion, and artichoke
  • Low-cost daily routines
  • General botanical liver support

Pros

  • Milk thistle is the lead ingredient
  • Complementary supporting botanicals
  • Very low serving cost

Cons

  • No extract standardization
  • Supporting doses are modest
  • No enhanced-absorption delivery

Warnings

  • Milk thistle may cause nausea, gas, or loose stools in sensitive users.
  • People allergic to ragweed, daisies, or related plants may also react to milk thistle.
  • Milk thistle may affect blood-sugar control; people using insulin or glucose-lowering medicine should check with their prescriber.

Nutrient quality

68 High impact

Three complementary botanicals provide coherent liver and bile-support coverage. Missing active standardization makes the apparent dose depth uncertain.

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Ingredient transparency

78 High impact

Individual amounts and the absence of a hidden blend support clear dose disclosure. Vague botanical forms plus missing usage and excipient details reduce specificity.

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Customer satisfaction

73 High impact

The average rating is exceptionally strong, and the feedback volume supports confidence in it. No specific experience details are supplied to assess recurring complaints or purpose fit.

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Value for money

85 Highest impact

Economical use and three relevant botanicals support strong practical value. Unstandardized extracts keep quality-adjusted value below the top tier.

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Report analysis

Goals

Detoxification
Detoxification
Impact
High effect
B Goal FitD+ Strength of SupportC- CoverageB+ Formula Quality
Milk Thistle · 300 mg

Milk thistle directly supports hepatocyte protection, while dandelion and artichoke add a plausible biliary and digestive component. None of the extracts includes active standardization, so their functional potency remains uncertain.

The formula offers complementary liver and bile-focused coverage with moderate depth. Its concise design is coherent, though the smaller supporting botanicals may contribute less than their presence suggests.

Study evidence
Milk Thistle Supportive 46 studies

Ingredients

IngredientAmount per serving
Milk Thistle extract
300 mg
Dandelion
100 mg
Artichoke
50 mg
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
Milk Thistle · 300 mg OverallScore23
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyC Value

The extract amount is substantial, but no silymarin percentage or active yield is provided. One dry capsule is convenient, yet the plant part and any absorption technology are not disclosed. The very low serving cost is favorable, though potency uncertainty remains.

View ingredientView products
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84 Performance

Milk Thistle

Kroeger Herb Products Co.
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the formula remains focused rather than broad.
82 Performance

Super Milk Thistle

Nature's Way
Clearly disclosed silybin and silymarin give the milk-thistle component unusually strong active characterization. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the added licorice may be unsuitable for some users.
84 Performance

Milk Thistle

Nature's Answer
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the formula remains focused rather than broad.
87 Budget

Milk Thistle Extract 175 mg

Lake Avenue Nutrition
A clearly labeled total-silymarin extract provides focused and readily assessable milk-thistle activity. A lower serving cost improves routine value, although the formula remains focused rather than broad.
77 Budget

Milk Thistle 30:1 Extract

Jarrow Formulas
A focused milk-thistle extract keeps the formula aligned with liver support, although the active silymarin yield is not stated. A lower serving cost improves routine value, although the active flavonolignan yield remains unclear.
80 Budget

Silymarin Complex

California Gold Nutrition
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. A lower serving cost improves routine value, although piperine can alter exposure to some medicines.
85 Value

Milk Thistle

Paradise
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
79 Value

Milk Thistle (Silymarin)

Mason Natural
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
79 Value

Milk Thistle

Solgar
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury.
    Shahsavari K; Ardekani SS; Ardekani MRS; Esfahani MM; Kazemizadeh H; Jamialahmadi T; Iranshahi M; Khanavi M; Hasanpour M · BMC complementary medicine and therapies · 2025
    Meta-analysis3,545 participants55 studies pooledDetoxification forMilk Thistle
  2. Evaluation of Hepatoprotective Effect of Silymarin Among Under Treatment Tuberculosis Patients: A Randomized Clinical Trial.
    Marjani M; Baghaei P; Kazempour Dizaji M; Gorji Bayani P; Fahimi F; Tabarsi P; Velayati AA · Iranian journal of pharmaceutical research : IJPR · 2016
    Randomized trial70 participantsDetoxification forMilk Thistle
  3. Effect of 8 Weeks milk thistle powder (silymarin extract) supplementation on fatty liver disease in patients candidates for bariatric surgery.
    Mirhashemi SH; Hakakzadeh A; Yeganeh FE; Oshidari B; Rezaee SP · Metabolism open · 2022
    Observational studyDetoxification forMilk Thistle
  4. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  5. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle
  6. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  7. The hepatorenal protective effects of silymarin in cancer patients receiving chemotherapy: a randomized, placebo-controlled trial.
    Erfanian SS; Ansari H; Javanmard SH; Amini Z; Hajigholami A · BMC complementary medicine and therapies · 2024
    Randomized trial100 participantsDetoxification forMilk Thistle
  8. A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury.
    Luangchosiri C; Thakkinstian A; Chitphuk S; Stitchantrakul W; Petraksa S; Sobhonslidsuk A · BMC complementary and alternative medicine · 2016
    Randomized trial55 participantsDetoxification forMilk Thistle
  9. A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis.
    El-Kamary SS; Shardell MD; Abdel-Hamid M; Ismail S; El-Ateek M; Metwally M; Mikhail N; Hashem M; Mousa A; Aboul-Fotouh A; El-Kassas M; Esmat G; Strickland GT · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2009
    Randomized trial105 participantsDetoxification forMilk Thistle
  10. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  11. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle