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Milk Thistle

4.7
★ ★ ★ ★ ★
(513 ratings)
Milk Thistle 750 mg
Product Image
Score66
A large, clean extract serving is appealing, but no verified silymarin yield supports the potency claim implied by its weight.
How scoring works
Capsule
Quantity:60 Capsule(s) • (60 servings)
Goals:
Detoxification

Score 66

A large, clean extract serving is appealing, but no verified silymarin yield supports the potency claim implied by its weight.
How scoring works
$25.00($0.41 per serving)
iHerb
$ 26.25
Vitacost
$ 28.59
Pure Formulas
$ 26.25
Amazon
$ 25.00
Vitacost
$ 28.59
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Analysis

A substantial extract amount gives the formula a clear liver-support purpose. Keeping the capsule to one botanical avoids filler actives and overlapping ingredients.

The label does not identify silymarin concentration, plant part, or an absorption-enhancing delivery system. A large extract weight can still contain an uncertain amount of the relevant active compounds.

The product fits someone who values a focused formula and is comfortable with incomplete potency data. Buyers comparing active dose or value precisely have stronger options.

Who is it for
  • Adults seeking a large total extract amount
  • People who prefer single-herb capsules
  • Users less concerned with active-marker disclosure
Best for
  • Focused liver antioxidant support
  • Minimal ingredient routines
  • Avoiding multi-herb formulas

Pros

  • Large extract weight
  • Single active ingredient
  • No proprietary blend

Cons

  • Silymarin yield is not stated
  • Plant part is unknown
  • Value is weak for the available detail

Warnings

  • Milk thistle may cause nausea, gas, or loose stools in sensitive users.
  • People allergic to ragweed, daisies, or related plants may also react to milk thistle.
  • Milk thistle may affect blood-sugar control; people using insulin or glucose-lowering medicine should check with their prescriber.

Nutrient quality

66 High impact

The single-herb design is focused and avoids low-value extras. Unspecified form and active yield make the large dose difficult to evaluate.

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Ingredient transparency

72 High impact

The total extract amount is stated and no hidden blend is present. Vague naming and missing usage, excipient, and standardization details weaken clarity.

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Customer satisfaction

69 High impact

The average rating is positive, and the available feedback volume provides useful confidence. No specific experience details are supplied to assess recurring complaints or purpose fit.

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Value for money

55 Moderate impact

A focused, filler-free design preserves some formula value. Above-average cost and unverified potency make it less competitive.

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Report analysis

Goals

Detoxification
Detoxification
Impact
Moderate effect
B Goal FitF Strength of SupportD CoverageA+ Formula Quality
Milk Thistle · 750 mg

Milk thistle is directly relevant to liver-cell protection, but the label gives only the total extract weight. Missing silymarin standardization prevents confirmation of an effective active dose.

The dry capsule offers no disclosed absorption support or plant-part information. The focused single-herb design avoids padding, yet its quality uncertainty is substantial.

Study evidence
Milk Thistle Supportive 46 studies

Ingredients

IngredientAmount per serving
Milk Thistle extract
750 mg
Gluten Free Adults 18–50
Report overview
Milk Thistle · 750 mg OverallScore12
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

The formula lists a large extract weight but does not disclose silymarin standardization or plant part. The active dose cannot be calculated, and the dry capsule provides no absorption technology. Its serving cost is above the collection median without enough quality detail to justify it.

View ingredientView products
Loading alternative details
84 Performance

Milk Thistle

Nature's Answer
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the formula remains focused rather than broad.
85 Performance

Milk Thistle

Paradise
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the formula remains focused rather than broad.
79 Performance

Milk Thistle (Silymarin)

Mason Natural
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the formula remains focused rather than broad.
84 Budget

Milk Thistle

Kroeger Herb Products Co.
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. A lower serving cost improves routine value, although the formula remains focused rather than broad.
82 Budget

Super Milk Thistle

Nature's Way
Clearly disclosed silybin and silymarin give the milk-thistle component unusually strong active characterization. A lower serving cost improves routine value, although the added licorice may be unsuitable for some users.
87 Budget

Milk Thistle Extract 175 mg

Lake Avenue Nutrition
A clearly labeled total-silymarin extract provides focused and readily assessable milk-thistle activity. A lower serving cost improves routine value, although the formula remains focused rather than broad.
79 Value

Milk Thistle

Solgar
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
82 Value

Milk Thistle Phytosome 300 mg

Swanson
A named milk-thistle phytosome provides a better-characterized absorption strategy than a basic, unstandardized herb amount. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
80 Value

Milk Thistle

Kirkman
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury.
    Shahsavari K; Ardekani SS; Ardekani MRS; Esfahani MM; Kazemizadeh H; Jamialahmadi T; Iranshahi M; Khanavi M; Hasanpour M · BMC complementary medicine and therapies · 2025
    Meta-analysis3,545 participants55 studies pooledDetoxification forMilk Thistle
  2. Evaluation of Hepatoprotective Effect of Silymarin Among Under Treatment Tuberculosis Patients: A Randomized Clinical Trial.
    Marjani M; Baghaei P; Kazempour Dizaji M; Gorji Bayani P; Fahimi F; Tabarsi P; Velayati AA · Iranian journal of pharmaceutical research : IJPR · 2016
    Randomized trial70 participantsDetoxification forMilk Thistle
  3. Effect of 8 Weeks milk thistle powder (silymarin extract) supplementation on fatty liver disease in patients candidates for bariatric surgery.
    Mirhashemi SH; Hakakzadeh A; Yeganeh FE; Oshidari B; Rezaee SP · Metabolism open · 2022
    Observational studyDetoxification forMilk Thistle
  4. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  5. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle
  6. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  7. The hepatorenal protective effects of silymarin in cancer patients receiving chemotherapy: a randomized, placebo-controlled trial.
    Erfanian SS; Ansari H; Javanmard SH; Amini Z; Hajigholami A · BMC complementary medicine and therapies · 2024
    Randomized trial100 participantsDetoxification forMilk Thistle
  8. A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury.
    Luangchosiri C; Thakkinstian A; Chitphuk S; Stitchantrakul W; Petraksa S; Sobhonslidsuk A · BMC complementary and alternative medicine · 2016
    Randomized trial55 participantsDetoxification forMilk Thistle
  9. A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis.
    El-Kamary SS; Shardell MD; Abdel-Hamid M; Ismail S; El-Ateek M; Metwally M; Mikhail N; Hashem M; Mousa A; Aboul-Fotouh A; El-Kassas M; Esmat G; Strickland GT · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2009
    Randomized trial105 participantsDetoxification forMilk Thistle
  10. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  11. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle