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Advanced Milk Thistle

4.7
★ ★ ★ ★ ★
(5894 ratings)
Milk Thistle 760 mg
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Score64
Phytosome delivery is a real strength, but poor dose transparency and a less economical package reduce the appeal.
How scoring works
Softgel
Quantity:60 Softgel(s) • (30 servings)
Goals:
Detoxification

Score 64

Phytosome delivery is a real strength, but poor dose transparency and a less economical package reduce the appeal.
How scoring works
$19.50($0.65 per serving)
Vitacost
$ 21.00
iHerb
$ 21.00
Amazon
$ 19.50
Vitacost
$ 21.00
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Analysis

Siliphos phytosome gives the formula a credible approach to improving delivery of milk thistle compounds. A phospholipid softgel is more purposeful than a standard dry capsule.

The proprietary milk thistle blend does not show component doses, while the phytosome entry omits silymarin standardization. As a result, the label cannot support a precise potency comparison.

The shorter supply and higher serving cost make the transparency gap more consequential. It fits someone specifically seeking this delivery system rather than the strongest value.

Who is it for
  • Adults who specifically want Siliphos
  • Softgel users
  • People willing to pay for phospholipid delivery
Best for
  • Absorption-focused supplementation
  • Shorter trial use
  • Single-botanical routines

Pros

  • Named phytosome complex
  • Softgel carrier
  • Focused formula

Cons

  • Unknown active silymarin dose
  • Proprietary blend is opaque
  • Less favorable serving value

Warnings

  • Milk thistle may cause nausea, gas, or loose stools in sensitive users.
  • People allergic to ragweed, daisies, or related plants may also react to milk thistle.
  • Milk thistle may affect blood-sugar control; people using insulin or glucose-lowering medicine should check with their prescriber.

Nutrient quality

76 High impact

Phytosome and phospholipid delivery provide a meaningful absorption advantage. Unknown active yield and overlapping complexes weaken dose quality and efficiency.

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Ingredient transparency

47 Lower impact

Named delivery systems and total amounts provide some useful label detail. The proprietary blend, unknown active yield, and missing usage details leave major gaps.

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Customer satisfaction

73 High impact

The average rating is positive, and the available feedback volume provides useful confidence. No specific experience details are supplied to assess recurring complaints or purpose fit.

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Value for money

65 High impact

Advanced delivery technology provides meaningful formula value. High serving cost, redundancy, and hidden potency weaken competitiveness.

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Report analysis

Goals

Detoxification
Impact
High effect
B+ Goal FitC- Strength of SupportC- CoverageA- Formula Quality
Milk Thistle · 160 mg

Milk thistle phytosome provides well-aligned liver antioxidant support with enhanced absorption. The label does not disclose silymarin standardization, so the actual active amount remains unknown.

The softgel and phospholipid system improve delivery compared with a plain extract. Two overlapping milk thistle complexes add some redundancy without resolving the missing active yield.

Study evidence
Milk Thistle Supportive 46 studies

Ingredients

IngredientAmount per serving
Milk Thistle Phospholipid Proprietary Blend
760 mg
Siliphos Phytosome Milk Thistle extract
160 mg
Gluten Free Adults 18–50
Report overview
Milk Thistle · 760 mg OverallScore43
C- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyA+ Value

Siliphos phytosome and a phospholipid softgel provide strong absorption support. The proprietary blend and missing silymarin yield prevent confirmation of the active dose or source plant part. Its serving cost remains within the premium allowance for phytosome technology.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  2. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  3. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  4. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle
  5. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle