Milk Thistle 500 mg Extended Release
Natures Plus Herbal Actives
Milk Thistle 500 mg Extended Release
4.6
★ ★ ★ ★ ★
(236 ratings)
Milk Thistle 500 mg
Score 80.0
An extremely potent, extended-release Milk Thistle with 1000mg Silymarin, offering maximum liver support but at a very high price.
Quantity: 30 Tablet(s)Servings size: 1 Tablet(s) (30 servings)
Selected goals:
Other goals:
Detoxification
Skin Health
leaderboard Score 80.0
An extremely potent, extended-release Milk Thistle with 1000mg Silymarin, offering maximum liver support but at a very high price.
insights Analysis
This Natures Plus Herbal Actives product delivers an impressive 1000mg of standardized Silymarin per serving, making it one of the most potent options available. The extended-release formulation suggests a sustained delivery of the active compounds, which can be beneficial for continuous liver support throughout the day. However, its most significant drawback is the very high price per serving of $0.99, which makes it considerably more expensive than most alternatives. This product is likely best suited for individuals requiring a very high dose, possibly under professional guidance, rather than for general, cost-conscious supplementation.
- Provides an exceptionally high 1000mg of standardized Silymarin, suitable for intensive liver support.
- Extended-release formulation ensures sustained delivery of active compounds, potentially increasing overall efficacy.
- Ideal for individuals with specific needs requiring high doses of Milk Thistle.
- Very high price per serving ($0.99), making it one of the most expensive options and not economical for general use.
- May be an excessively high dose for many general users, leading to unnecessary cost.
- Due to its very high potency, it's advisable to consult a healthcare professional before taking, especially if you have existing health conditions or are on medication.
$29.71($0.99 per serving)
 iHerb | $ 29.71 | |
 Vitacost | $ 29.71 | |
 Amazon | $ 33.40 |
bolt Effectiveness for goals
Milk Thistle, primarily through its active compound silymarin, is widely studied for its potential to support liver health. Research suggests it may offer antioxidant and anti-inflammatory benefits to liver cells. However, more comprehensive studies are ongoing to fully understand its extent of effectiveness.
Historically, Milk Thistle has been used in relation to alcoholic liver disease, and some studies suggest it may help shield liver cells from alcohol-related harm. While it shows potential, it is not considered a cure or a replacement for conventional medical treatment and abstinence. Its role is primarily supportive.
Milk Thistle is often associated with supporting the liver's natural detoxification processes due to its antioxidant properties. It may help protect liver cells from damage by harmful substances. However, the human body has its own efficient detoxification systems, and the term 'detoxification' can be broadly interpreted.
The general scientific consensus is that Milk Thistle shows promise as a supportive supplement for liver health, backed by traditional use and some research. While it's not a proven cure for severe liver diseases, it's considered a potentially beneficial agent for liver protection. More large-scale, high-quality human trials are needed to fully confirm its efficacy for various conditions.
Some preliminary studies indicate Milk Thistle may offer benefits for individuals with NAFLD, potentially by reducing inflammation and oxidative stress in the liver. Despite promising early findings, the current scientific evidence is not strong enough to recommend it as a primary treatment. Consultation with a healthcare professional is advised.
schedule Dosage, timing & forms
Typical daily dosages of Milk Thistle extract often range from 200 mg to 400 mg, standardized to 70-80% silymarin. Some research has explored higher doses for specific contexts. For general use, dosages usually fall within the 200-400 mg range, often divided into multiple smaller doses throughout the day.
Milk Thistle is generally recommended to be taken with food. This can help improve the absorption of its active compounds, particularly silymarin. Taking it with food may also help reduce the likelihood of minor digestive upset.
Many formulations of Milk Thistle recommend taking it two to three times per day. Dividing the daily dose helps maintain consistent levels of its active compounds in the body. Always refer to the specific product label for detailed instructions.
Milk Thistle is commonly available as capsules, tablets, and liquid extracts. It can also be found in tea bags or powder form. Capsules and tablets are the most prevalent, often standardized for their silymarin content.
Standardization means the extract is processed to contain a specific, guaranteed percentage of the active compound, silymarin. This process helps ensure consistency in potency between different batches and brands of the supplement. A common standardization level is 70-80% silymarin.
health_and_safety Safety & interactions
Yes, milk thistle can interact with certain prescription medications, particularly those metabolized by the cytochrome P450 enzyme system in the liver. This could potentially alter how the body processes drugs, affecting their effectiveness or increasing side effects. It is important to consult a healthcare professional before combining milk thistle with any medications.
Milk thistle is generally well-tolerated, but some individuals may experience mild gastrointestinal upset, such as nausea, diarrhea, or indigestion. Allergic reactions are also possible, especially in individuals sensitive to plants in the Asteraceae family. If severe or persistent side effects occur, discontinue use and consult a healthcare provider.
Some research suggests that milk thistle might have mild antiplatelet effects, which theoretically could increase the risk of bleeding when taken with anticoagulant or antiplatelet medications. However, the evidence for this interaction is limited and conflicting. Individuals on blood thinners should discuss milk thistle use with their healthcare provider.
Milk thistle may have a mild blood sugar-lowering effect, particularly in individuals with type 2 diabetes. Those managing diabetes or taking medications to control blood sugar should monitor their glucose levels closely if using milk thistle. Discussing this with a healthcare provider is advised to prevent potential hypoglycemia.
Due to insufficient scientific data on its safety during pregnancy and breastfeeding, milk thistle is generally not recommended for these populations. There is limited information regarding its potential effects on the fetus or infant. It is always best to consult a healthcare provider before using any supplements during these periods.
Ingredients
| Ingredient | Amount per serving |
|---|---|
Milk Thistle | 500 mg |
Categories
Milk Thistle 85.0
This product is a top-tier option in the Milk Thistle category in terms of sheer potency, offering a very high standardized Silymarin dose. Its extended-release feature also sets it apart, making it highly effective for specialized needs despite the high cost.
Goals
Detoxification 90.0
The 1000mg of standardized Silymarin, combined with extended release, provides powerful and sustained support for liver detoxification, making it highly effective for cleansing and protecting liver cells. This high dose is beneficial for demanding detoxification needs.
Skin Health 80.0
Through its maximal liver support and detoxification capabilities, this product offers significant indirect benefits to skin health, potentially leading to noticeable improvements in clarity and overall appearance by reducing systemic toxic burden.
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This alternative provides 350mg of standardized Silymarin at an exceptionally low price per serving ($0.07), offering excellent value and clear potency, which drastically outperforms the original's very high cost-effectiveness for liver support.
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Advanced Milk Thistle
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