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Milk Thistle 250 mg

4.9
★ ★ ★ ★ ★
(62 ratings)
Milk Thistle 250 mg
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Score74
Focused and reasonably priced, but ambiguous silymarin labeling prevents a confident potency assessment.
How scoring works
Capsule
Quantity:60 Capsule(s) • (60 servings)
Goals:
Detoxification

Score 74

Focused and reasonably priced, but ambiguous silymarin labeling prevents a confident potency assessment.
How scoring works
$17.32($0.28 per serving)
iHerb
$ 28.86
Vitacost
$ 28.86
iHerb
$ 17.32
Pure Formulas
$ 28.86
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Analysis

Milk thistle gives the product a clear liver-support purpose, and no unrelated botanicals dilute that focus. The total ingredient weight is easy to see.

Silymarin appears as the form, yet the label does not clarify whether the amount represents active silymarin or a broader extract. No standardization percentage, plant part, or absorption feature is supplied.

The moderate serving cost is reasonable only if the extract is adequately concentrated. Shoppers who want measurable potency should favor a label that states the active-marker yield.

Who is it for
  • Adults wanting a simple milk thistle capsule
  • People avoiding proprietary blends
  • Shoppers comfortable with moderate label uncertainty
Best for
  • Basic liver antioxidant support
  • Minimalist supplement routines
  • Single-herb use

Pros

  • Focused ingredient list
  • Meaningful total amount
  • No hidden blend

Cons

  • Active silymarin amount is unclear
  • Plant part is not listed
  • No enhanced-absorption format

Warnings

  • Milk thistle may cause nausea, gas, or loose stools in sensitive users.
  • People allergic to ragweed, daisies, or related plants may also react to milk thistle.
  • Milk thistle may affect blood-sugar control; people using insulin or glucose-lowering medicine should check with their prescriber.

Nutrient quality

74 High impact

The focused formula fits liver support without obvious padding or excess. Unknown active yield and basic delivery limit confidence in dose quality.

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Ingredient transparency

75 High impact

The single active amount is stated and no hidden blend complicates the label. Usage, excipient, plant-source, and standardization details remain incomplete.

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Customer satisfaction

64 Moderate impact

The average rating is exceptionally strong, and the feedback volume supports confidence in it. No specific experience details are supplied to assess recurring complaints or purpose fit.

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Value for money

80 Highest impact

Reasonable serving cost and a filler-free design support acceptable value. Unverified potency keeps it from matching more transparent alternatives.

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Goals

Detoxification
Detoxification
Impact
High effect
A- Goal FitC- Strength of SupportD- CoverageA+ Formula Quality
Milk Thistle · 250 mg

Milk thistle gives the formula a direct and credible liver-support focus. Its listed silymarin form is relevant to antioxidant protection during normal metabolic processing.

The label does not reveal an extract standardization percentage, plant part, or calculable active silymarin amount. A higher total extract amount is promising, but those omissions make true potency uncertain.

Study evidence
Milk Thistle Supportive 46 studies

Ingredients

IngredientAmount per serving
Milk Thistle (Silymarin)
 250 mg
Gluten Free Adults 18–50 Dairy Free
Report overview
Milk Thistle (Silymarin) · 250 mg OverallScore20
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyC Value

The low serving cost is appealing, and silymarin is identified on the ingredient entry. The label does not clearly state an extract standardization, plant part, or calculable active silymarin amount. Its basic dry capsule also offers no stated absorption support.

View ingredientView products
Loading alternative details
84 Performance

Milk Thistle

Nature's Answer
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the formula remains focused rather than broad.
85 Performance

Milk Thistle

Paradise
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the formula remains focused rather than broad.
79 Performance

Milk Thistle (Silymarin)

Mason Natural
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the formula remains focused rather than broad.
84 Budget

Milk Thistle

Kroeger Herb Products Co.
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. A lower serving cost improves routine value, although the formula remains focused rather than broad.
82 Budget

Super Milk Thistle

Nature's Way
Clearly disclosed silybin and silymarin give the milk-thistle component unusually strong active characterization. A lower serving cost improves routine value, although the added licorice may be unsuitable for some users.
87 Budget

Milk Thistle Extract 175 mg

Lake Avenue Nutrition
A clearly labeled total-silymarin extract provides focused and readily assessable milk-thistle activity. A lower serving cost improves routine value, although the formula remains focused rather than broad.
79 Value

Milk Thistle

Solgar
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
82 Value

Milk Thistle Phytosome 300 mg

Swanson
A named milk-thistle phytosome provides a better-characterized absorption strategy than a basic, unstandardized herb amount. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
80 Value

Milk Thistle

Kirkman
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury.
    Shahsavari K; Ardekani SS; Ardekani MRS; Esfahani MM; Kazemizadeh H; Jamialahmadi T; Iranshahi M; Khanavi M; Hasanpour M · BMC complementary medicine and therapies · 2025
    Meta-analysis3,545 participants55 studies pooledDetoxification forMilk Thistle
  2. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle
  3. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  4. A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury.
    Luangchosiri C; Thakkinstian A; Chitphuk S; Stitchantrakul W; Petraksa S; Sobhonslidsuk A · BMC complementary and alternative medicine · 2016
    Randomized trial55 participantsDetoxification forMilk Thistle
  5. Effect of 8 Weeks milk thistle powder (silymarin extract) supplementation on fatty liver disease in patients candidates for bariatric surgery.
    Mirhashemi SH; Hakakzadeh A; Yeganeh FE; Oshidari B; Rezaee SP · Metabolism open · 2022
    Observational studyDetoxification forMilk Thistle
  6. A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis.
    El-Kamary SS; Shardell MD; Abdel-Hamid M; Ismail S; El-Ateek M; Metwally M; Mikhail N; Hashem M; Mousa A; Aboul-Fotouh A; El-Kassas M; Esmat G; Strickland GT · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2009
    Randomized trial105 participantsDetoxification forMilk Thistle
  7. Evaluation of Hepatoprotective Effect of Silymarin Among Under Treatment Tuberculosis Patients: A Randomized Clinical Trial.
    Marjani M; Baghaei P; Kazempour Dizaji M; Gorji Bayani P; Fahimi F; Tabarsi P; Velayati AA · Iranian journal of pharmaceutical research : IJPR · 2016
    Randomized trial70 participantsDetoxification forMilk Thistle
  8. The hepatorenal protective effects of silymarin in cancer patients receiving chemotherapy: a randomized, placebo-controlled trial.
    Erfanian SS; Ansari H; Javanmard SH; Amini Z; Hajigholami A · BMC complementary medicine and therapies · 2024
    Randomized trial100 participantsDetoxification forMilk Thistle
  9. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  10. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  11. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle