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Milk Thistle

4.7
★ ★ ★ ★ ★
(1795 ratings)
Milk Thistle 1260 mg
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Score70
Organic seed sourcing is appealing, but unstandardized powder dominates and the active silymarin yield is unknown.
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Capsule
Quantity:90 Capsule(s) • (30 servings)
Goals:

Score 70

Organic seed sourcing is appealing, but unstandardized powder dominates and the active silymarin yield is unknown.
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Also available as

1 option
180 servings Milk Thistle 1260 mg • 180 Capsule(s) • 60 servings $47.96 ($0.79 per serving)
$29.56($0.98 per serving)
iHerb
$ 29.56
Vitacost
$ 29.56
Pure Formulas
$ 29.56
Amazon
$ 29.56
Vitacost
$ 29.56
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Analysis

Organic milk thistle seed and a separately listed seed extract keep the formula closely aligned with liver and antioxidant support. Identifying the seed source is more useful than a generic plant-only label.

Most of the serving comes from raw seed powder, while the 240 mg extract does not state a silymarin percentage. The large total botanical weight therefore should not be read as a confirmed high active dose.

Three capsules per serving and a comparatively costly daily serving reduce convenience and value. It suits shoppers who prefer organic whole-herb content more than those seeking concentrated, precisely standardized silymarin.

Who is it for
  • Adults who prefer organic botanicals
  • Users comfortable with multi-capsule servings
Best for
  • Whole-seed plus extract supplementation
  • Organic-focused purchasing

Pros

  • Organic milk thistle seed
  • Seed plant part is identified
  • Separate extract weight is disclosed

Cons

  • No silymarin percentage
  • Most weight comes from raw seed powder
  • Three-capsule serving

Warnings

  • Milk thistle can cause digestive upset in some users; stop or reduce use if symptoms persist.
  • People allergic to ragweed-family plants may also react to milk thistle.
  • Milk thistle may affect blood sugar, so people using glucose-lowering medicine should discuss it with their clinician.

Nutrient quality

77 High impact

Organic sourcing and use of the seed are quality strengths. A large whole-herb amount is paired with extract, but missing standardization leaves functional potency uncertain.

Ingredient transparency

78 High impact

The active ingredient has a stated amount without a hidden proprietary blend. Standardization or source details, daily-use directions, and non-active ingredients remain incomplete.

Customer satisfaction

70 High impact

The supplied average rating is very strong and is supported by substantial review count. No detailed feedback is available to assess repeated complaints or purpose-specific experiences.

Value for money

51 Moderate impact

Organic sourcing and substantial botanical weight provide some formula value. A high qualitative serving cost is difficult to justify without a verified active yield.

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Ingredients

IngredientAmount per serving
organic Milk Thistle
1260 mg
organic Milk Thistle seed powdered extract (Silymarin)
 240 mg
Gluten Free Adults 18–50 Dairy Free Organic
Report overview
Milk Thistle · 1260 mg OverallScore15
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

The seed source is clearly identified, which supports appropriate plant-part selection. Most of the formula is raw seed powder, while the extract lacks a stated silymarin percentage and has no absorption technology. The high serving cost is difficult to justify without a verified active dose.

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84 Performance

Milk Thistle

Nature's Answer
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the formula remains focused rather than broad.
85 Performance

Milk Thistle

Paradise
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the formula remains focused rather than broad.
79 Performance

Milk Thistle (Silymarin)

Mason Natural
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the formula remains focused rather than broad.
84 Budget

Milk Thistle

Kroeger Herb Products Co.
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. A lower serving cost improves routine value, although the formula remains focused rather than broad.
82 Budget

Super Milk Thistle

Nature's Way
Clearly disclosed silybin and silymarin give the milk-thistle component unusually strong active characterization. A lower serving cost improves routine value, although the added licorice may be unsuitable for some users.
87 Budget

Milk Thistle Extract 175 mg

Lake Avenue Nutrition
A clearly labeled total-silymarin extract provides focused and readily assessable milk-thistle activity. A lower serving cost improves routine value, although the formula remains focused rather than broad.
79 Value

Milk Thistle

Solgar
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
82 Value

Milk Thistle Phytosome 300 mg

Swanson
A named milk-thistle phytosome provides a better-characterized absorption strategy than a basic, unstandardized herb amount. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
80 Value

Milk Thistle

Kirkman
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury.
    Shahsavari K; Ardekani SS; Ardekani MRS; Esfahani MM; Kazemizadeh H; Jamialahmadi T; Iranshahi M; Khanavi M; Hasanpour M · BMC complementary medicine and therapies · 2025
    Meta-analysis3,545 participants55 studies pooledDetoxification forMilk Thistle
  2. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle
  3. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  4. A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury.
    Luangchosiri C; Thakkinstian A; Chitphuk S; Stitchantrakul W; Petraksa S; Sobhonslidsuk A · BMC complementary and alternative medicine · 2016
    Randomized trial55 participantsDetoxification forMilk Thistle
  5. Effect of 8 Weeks milk thistle powder (silymarin extract) supplementation on fatty liver disease in patients candidates for bariatric surgery.
    Mirhashemi SH; Hakakzadeh A; Yeganeh FE; Oshidari B; Rezaee SP · Metabolism open · 2022
    Observational studyDetoxification forMilk Thistle
  6. A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis.
    El-Kamary SS; Shardell MD; Abdel-Hamid M; Ismail S; El-Ateek M; Metwally M; Mikhail N; Hashem M; Mousa A; Aboul-Fotouh A; El-Kassas M; Esmat G; Strickland GT · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2009
    Randomized trial105 participantsDetoxification forMilk Thistle
  7. Evaluation of Hepatoprotective Effect of Silymarin Among Under Treatment Tuberculosis Patients: A Randomized Clinical Trial.
    Marjani M; Baghaei P; Kazempour Dizaji M; Gorji Bayani P; Fahimi F; Tabarsi P; Velayati AA · Iranian journal of pharmaceutical research : IJPR · 2016
    Randomized trial70 participantsDetoxification forMilk Thistle
  8. The hepatorenal protective effects of silymarin in cancer patients receiving chemotherapy: a randomized, placebo-controlled trial.
    Erfanian SS; Ansari H; Javanmard SH; Amini Z; Hajigholami A · BMC complementary medicine and therapies · 2024
    Randomized trial100 participantsDetoxification forMilk Thistle
  9. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  10. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle