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Milk Thistle Extract 300 mg

4.8
★ ★ ★ ★ ★
(315 ratings)
Milk Thistle 300 mg
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Score73
A coherent three-herb blend broadens digestive support, but undisclosed silymarin potency and light supporting doses limit certainty.
How scoring works
Capsule
Quantity:90 Capsule(s) • (90 servings)
Goals:
Detoxification

Score 73

A coherent three-herb blend broadens digestive support, but undisclosed silymarin potency and light supporting doses limit certainty.
How scoring works
$24.80($0.27 per serving)
Vitacost
$ 32.00
iHerb
$ 32.00
Pure Formulas
$ 32.00
Amazon
$ 24.80
iHerb
$ 32.00
Vitacost
$ 32.00
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Analysis

Milk thistle provides the main antioxidant and liver-cell support, while dandelion and artichoke add a related digestive and bile-flow angle. The three-botanical design is coherent rather than crowded.

Each botanical weight is disclosed, including 300 mg of milk thistle extract. The silymarin percentage is not shown, however, and the smaller dandelion and artichoke amounts may offer only modest secondary support.

The formula fits adults who want more pathway breadth than a single milk-thistle capsule. People with gallstones or bile-duct concerns need more caution because dandelion and artichoke may stimulate bile flow.

Who is it for
  • Adults seeking liver and digestive support
  • People wanting a multi-herb capsule
Best for
  • Broader botanical pathway coverage
  • Milk thistle with dandelion and artichoke

Pros

  • All botanical weights are listed
  • Coherent liver-support blend
  • Meaningful milk thistle extract amount

Cons

  • No silymarin percentage
  • Supporting herbs are lightly dosed
  • No stated absorption technology

Warnings

  • Dandelion and artichoke may stimulate bile flow; seek advice before use with gallstones or bile-duct obstruction.
  • Milk thistle, dandelion, and artichoke can trigger reactions in people sensitive to ragweed-family plants.
  • Dandelion may increase urination and can be a poor fit with prescription diuretics.

Nutrient quality

77 High impact

Silymarin flavonoids are named, while dandelion and artichoke fit the broader liver-digestive purpose. Missing standardization and modest supporting-herb doses limit dependable potency.

Ingredient transparency

77 High impact

Each botanical has a stated amount and no blend hides its dose. Milk-thistle standardization, daily-use directions, and non-active ingredients are missing.

Customer satisfaction

67 High impact

The supplied average rating is very strong and is supported by limited review count. No detailed feedback is available to assess repeated complaints or purpose-specific experiences.

Value for money

70 High impact

A coherent three-botanical formula and practical serving provide fair value. Missing silymarin potency and modest supporting herbs limit formula depth.

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Goals

Detoxification
Impact
Moderate effect
B- Goal FitF Strength of SupportD+ CoverageB Formula Quality
Milk Thistle · 300 mg

Milk thistle provides the main liver-protective role, while dandelion and artichoke add biliary and digestive support. The combination is relevant to natural clearance but does not supply glutathione precursors or mineral cofactors.

All botanical weights are visible, yet the silymarin percentage and active amount are missing. A basic dry capsule and lightly dosed supporting herbs limit dependable pathway depth.

Study evidence
Milk Thistle Supportive 46 studies

Ingredients

IngredientAmount per serving
Milk Thistle extract (Silymarin Flavonoids)
300 mg
Dandelion
100 mg
Artichoke
50 mg
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

The extract names silymarin flavonoids but does not disclose their percentage or the source plant part. A plain capsule has no identified absorption technology. Its low cost cannot be tied to a verified effective dose.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury.
    Shahsavari K; Ardekani SS; Ardekani MRS; Esfahani MM; Kazemizadeh H; Jamialahmadi T; Iranshahi M; Khanavi M; Hasanpour M · BMC complementary medicine and therapies · 2025
    Meta-analysis3,545 participants55 studies pooledDetoxification forMilk Thistle
  2. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle
  3. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  4. A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury.
    Luangchosiri C; Thakkinstian A; Chitphuk S; Stitchantrakul W; Petraksa S; Sobhonslidsuk A · BMC complementary and alternative medicine · 2016
    Randomized trial55 participantsDetoxification forMilk Thistle
  5. Effect of 8 Weeks milk thistle powder (silymarin extract) supplementation on fatty liver disease in patients candidates for bariatric surgery.
    Mirhashemi SH; Hakakzadeh A; Yeganeh FE; Oshidari B; Rezaee SP · Metabolism open · 2022
    Observational studyDetoxification forMilk Thistle
  6. A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis.
    El-Kamary SS; Shardell MD; Abdel-Hamid M; Ismail S; El-Ateek M; Metwally M; Mikhail N; Hashem M; Mousa A; Aboul-Fotouh A; El-Kassas M; Esmat G; Strickland GT · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2009
    Randomized trial105 participantsDetoxification forMilk Thistle
  7. Evaluation of Hepatoprotective Effect of Silymarin Among Under Treatment Tuberculosis Patients: A Randomized Clinical Trial.
    Marjani M; Baghaei P; Kazempour Dizaji M; Gorji Bayani P; Fahimi F; Tabarsi P; Velayati AA · Iranian journal of pharmaceutical research : IJPR · 2016
    Randomized trial70 participantsDetoxification forMilk Thistle
  8. The hepatorenal protective effects of silymarin in cancer patients receiving chemotherapy: a randomized, placebo-controlled trial.
    Erfanian SS; Ansari H; Javanmard SH; Amini Z; Hajigholami A · BMC complementary medicine and therapies · 2024
    Randomized trial100 participantsDetoxification forMilk Thistle
  9. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  10. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  11. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle