Bromelain 500 mg

Bromelain 500 mg

California Gold Nutrition4.7 (6,377 ratings)
Format:Capsule Quantity: 90 Capsule(s) · 90 servings
Goals
$15.16 $0.16 per serving

Product analysis

61 out of 100

Bromelain 500 mg supplies an enzyme that helps digest dietary protein. Noticeable digestive relief and joint-comfort benefits remain uncertain.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality20

Bromelain preparation quality remains uncertain because its form is unspecified. The amount alone does not explain how it compares with other preparations.

Ingredient Transparency63

The bromelain amount is disclosed, making serving strength straightforward to compare. Its form is not identified, leaving the preparation less clear.

Value For Money100

The declared bromelain amount offers favorable value at the serving price, making the ingredient economical compared with costlier servings.

Customer Satisfaction89

Customer ratings are positive across a large number of reviews. The feedback supports general satisfaction without confirming effectiveness.

Product Focus60

The single enzyme has a clear role in breaking down dietary protein. Findings for noticeable digestive relief, joint symptoms and broader inflammation benefits remain limited and mixed.

Format
Capsule
Container
90 Capsule(s)
Per serving
$0.16
Customer rating
4.7 · 6,377 ratings
Report analysis

Goals

Gut Health
Impact
Moderate effect
A+ Ingredient FitC PathwaysC- EvidenceA+ Formulation Logic
Bromelain · 500 mg

Bromelain at 500 mg provides a protein-digesting enzyme, so its main relevance is helping break down dietary protein. Evidence for noticeable digestive symptom relief is limited and mixed.

How this product is rated for Gut Health

Ingredient fit96

The assessed ingredient is closely focused on the digestive contribution described here. The declared amount reaches the full amount used in the saved assessment.
Goal fit
The assessed ingredient is closely focused on the digestive contribution described here.
Dose adequacy
The declared amount reaches the full amount used in the saved assessment.

Pathways60

Protein digestion is the main area supported by the enzyme's activity. The saved findings show one main area of digestive support.
Depth
Protein digestion is the main area supported by the enzyme's activity.
Breadth
The saved findings show one main area of digestive support.

Evidence58

The supplied evidence is limited and mixed for digestive outcomes. The saved findings recognize the preparation, although this alone does not promise symptom relief.
Evidence strength
The supplied evidence is limited and mixed for digestive outcomes.
Studied preparation
The saved findings recognize the preparation, although this alone does not promise symptom relief.

Formulation logic100

The assessed ingredient reaches the minimum contribution threshold in the saved findings. No ingredient conflict was identified in the supplied assessment.
Partner coverage
The assessed ingredients do not require a missing partner for their assigned contribution.
Conflicts
No ingredient conflict was identified in the supplied assessment.
Effective doses
The assessed ingredient reaches the minimum contribution threshold in the saved findings.
Study evidence
Bromelain Supportive 2 studies
Inflammation
Impact
Moderate effect
A+ Ingredient FitF PathwaysC EvidenceA+ Formulation Logic

Bromelain at 500 mg is a pineapple enzyme with a possible role in inflammation-related enzyme activity and discomfort. The supplied findings are mixed and mainly concern joint symptoms or recovery after dental surgery, so broader benefits remain uncertain.

How this product is rated for Inflammation

Ingredient fit96

The relevant ingredients give a focused contribution to the goal. The assessed relevant amounts align closely with the supplied dose comparisons.
Goal fit
The relevant ingredients give a focused contribution to the goal.
Dose adequacy
The assessed relevant amounts align closely with the supplied dose comparisons.

Pathways18

COX and LOX enzyme inhibition is the main area of support, with limited coverage in the saved findings. The saved findings show limited reach across the different aspects of inflammation support.
Depth
COX and LOX enzyme inhibition is the main area of support, with limited coverage in the saved findings.
Breadth
The saved findings show limited reach across the different aspects of inflammation support.

Evidence62

Bromelain provides the strongest relevant human evidence at the assessed amount, although practical benefits depend on context. The qualifying ingredients match preparations represented in the supplied evidence.
Evidence strength
Bromelain provides the strongest relevant human evidence at the assessed amount, although practical benefits depend on context.
Studied preparation
The qualifying ingredients match preparations represented in the supplied evidence.

Formulation logic100

The assessed ingredients can contribute on their own or have their required partner present. No ingredient conflicts were identified in the saved assessment. All assessed ingredients met the saved minimum amount criterion.
Partner coverage
The assessed ingredients can contribute on their own or have their required partner present.
Conflicts
No ingredient conflicts were identified in the saved assessment.
Effective doses
All assessed ingredients met the saved minimum amount criterion.
Study evidence
Bromelain Supportive 12 studies
Joint Health
Impact
Moderate effect
B Ingredient FitF PathwaysC EvidenceA+ Formulation Logic

Bromelain is included for an inflammation-related joint role, but the supplied osteoarthritis trials were null or inconclusive. The placebo-controlled pilot found no clear symptom advantage, and an active-comparator trial could not establish a reliable difference. A predictable joint-comfort benefit remains uncertain.

How this product is rated for Joint Health

Ingredient fit79

Bromelain supplies the main connection in the saved findings, with the strength of its practical role limited by the supplied evidence.
Goal fit
Bromelain supplies the main connection in the saved findings, with the strength of its practical role limited by the supplied evidence.
Dose adequacy
Declared amounts provide partial support against the saved benchmarks; these comparisons are not measured probabilities of symptom relief.

Pathways12

The saved findings center on inflammation-related symptom support, rather than lubrication, oral collagen tolerance or structural repair. No assessed joint process reaches the saved threshold for substantial coverage.
Depth
The saved findings center on inflammation-related symptom support, rather than lubrication, oral collagen tolerance or structural repair.
Breadth
No assessed joint process reaches the saved threshold for substantial coverage.

Evidence62

Bromelain's supplied osteoarthritis trials were null or inconclusive, leaving symptom benefit uncertain.
Evidence strength
Bromelain's supplied osteoarthritis trials were null or inconclusive, leaving symptom benefit uncertain.
Studied preparation
The included preparations are accepted in the saved findings, without establishing identical clinical effects, absorption or regimen equivalence.

Formulation logic100

No required ingredient partner is missing, and no assessed ingredient conflict was found.
Partner coverage
Included ingredients have no required partner missing; this does not imply added benefit from combining them.
Conflicts
No assessed ingredient conflict was found in the supplied facts.
Effective doses
All included ingredients meet the saved minimum amount for inclusion, which is not a universal effective joint-symptom dose.
Study evidence

Ingredients

IngredientAmount per servingScore
Bromelain
500 mg 89
Gluten Free Adults 18–50
Report overview
Bromelain · 500 mg OverallScore89
A+ Composition And Label DisclosureB- Composition And Label DisclosureA+ Commercial Price And Usability
Each serving lists 500 mg of bromelain with declared activity of 3000 GDU per gram. The whole-product cost works out to about $0.17 per 500 mg of declared bromelain.
How this ingredient is rated

Composition and Label Disclosure100

Bromelain activity is declared at 3000 GDU per gram. Activity is a label measure and does not establish clinical effects.
Enzyme Activity Disclosure
The saved facts report enzyme activity of 3000 GDU per gram of bromelain.
Declared GDU per Gram
The declared concentration is 3000 GDU per gram; activity is a label measure, not proof of clinical effects.

Composition and Label Disclosure73

The declared amount is 500 mg of bromelain per serving. The saved facts do not establish the botanical source of the bromelain.
Declared Bromelain Mass
The declared amount is 500 mg of bromelain per serving.
Botanical Source Disclosure
The saved facts do not establish the botanical source of the bromelain.

Commercial Price and Usability100

The whole-product cost works out to about $0.17 per 500 mg of declared bromelain.
Cost per 500 mg Declared Bromelain
The whole-product cost works out to about $0.17 per 500 mg of declared bromelain.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The role of enzyme supplementation in digestive disorders.
    Roxas M · Alternative medicine review : a journal of clinical therapeutic · 2009
    Narrative reviewGut Health forBromelain
  2. Effects of bromelain supplementation on disease activity and quality of life in patients with ulcerative colitis: a randomized, triple-blind, placebo-controlled study.
    Delgarm P; Mokhtare M; Ebrahimi Daryani N; Abolghasemi J; Rahideh ST · Scientific reports · 2025
    Randomized trial70 participantsGut Health forBromelain
  3. Therapeutic efficacy of bromelain in impacted third molar surgery: a randomized controlled clinical study.
    Ordesi P; Pisoni L; Nannei P; Macchi M; Borloni R; Siervo S · Quintessence international (Berlin, Germany : 1985) · 2016
    Randomized trial80 participantsInflammation forBromelain
  4. Efficacy of proteolytic enzyme bromelain on health outcomes after third molar surgery. Systematic review and meta-analysis of randomized clinical trials.
    Mendes ML; do Nascimento-Júnior EM; Reinheimer DM; Martins-Filho PR · Medicina oral, patologia oral y cirugia bucal · 2019
    Meta-analysis6 studies pooledInflammation forBromelain
  5. Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - new evidence on the antiinflammatory mode of action of bromelain.
    Müller S; März R; Schmolz M; Drewelow B; Eschmann K; Meiser P · Phytotherapy research : PTR · 2013
    Randomized trial12 participantsInflammation forBromelain
  6. An Evaluation of the Effects of Pineapple-Extract and Bromelain-Based Treatment after Mandibular Third Molar Surgery: A Randomized Three-Arm Clinical Study.
    Colletti A; Procchio C; Pisano M; Martelli A; Pellizzato M; Cravotto G · Nutrients · 2024
    Randomized trial42 participantsInflammation forBromelain
  7. Therapeutic uses of pineapple-extracted bromelain in surgical care - A review.
    Muhammad ZA; Ahmad T · JPMA. The Journal of the Pakistan Medical Association · 2019
    Narrative reviewInflammation forBromelain
  8. Bromelain as a Treatment for Osteoarthritis: a Review of Clinical Studies.
    Brien S; Lewith G; Walker A; Hicks SM; Middleton D · Evidence-based complementary and alternative medicine : eCAM · 2024
    Narrative reviewJoint Health forBromelain
  9. Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis.
    Kasemsuk T; Saengpetch N; Sibmooh N; Unchern S · Clinical rheumatology · 2017
    Randomized trial40 participantsJoint Health forBromelain
  10. Oral enzyme combination therapy reduces systemic inflammation, urinary CTXII and pain in knee osteoarthritis: a proof-of-mechanism, randomised, crossover, double-blind, placebo-controlled trial.
    Henrotin Y; Pap T; Lieten S; Badot V; Dubuc JE; Urbin-Choffray D; von Eynatten M; Johansen OE; Rau S; Brabants K · RMD open · 2025
    Randomized trial45 participantsJoint Health forBromelain
  11. Efficacy, tolerability, and safety of an oral enzyme combination vs diclofenac in osteoarthritis of the knee: results of an individual patient-level pooled reanalysis of data from six randomized controlled trials
    Ueberall MA, Mueller-Schwefe GH, Wigand R, Essner U · Journal of Pain Research · 2016
    Meta-analysis697 participants6 studies pooledJoint Health forBromelain
  12. The safety and efficacy of an enzyme combination in managing knee osteoarthritis pain in adults: a randomized, double-blind, placebo-controlled trial
    Bolten WW, Glade MJ, Raum S, Ritz BW · Arthritis · 2015
    Randomized trial150 participantsJoint Health forBromelain