Specially-Coated Bromelain 500 mg

Specially-Coated Bromelain 500 mg

Life Extension4.6 (2,627 ratings)
Format:Tablet Quantity: 60 Tablet(s) · 60 servings
Goals
$15.75 $0.26 per serving
iHerbLowest$15.75Vitacost$15.75Pure Formulas$15.75Amazon$15.75

Product analysis

68 out of 100

Specially-Coated Bromelain 500 mg supplies a favorably priced protein-digesting enzyme. Practical benefits for everyday digestive symptoms or joint comfort remain uncertain.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality40

The pineapple source is identified, but a firm comparison of the enzyme preparation's quality is unavailable. The coating alone does not establish an added practical advantage.

Ingredient Transparency100

Amounts and forms are clearly identified. That makes the serving and ingredient choices easier to compare.

Value For Money72

The bromelain content is favorably priced in its comparison. A missing calcium comparison leaves the value of the full combination less certain.

Customer Satisfaction84

Customer ratings are favorable, with a substantial review pool. Reviews describe satisfaction without establishing effectiveness or safety.

Product Focus60

Bromelain has a clear role in breaking down proteins. Evidence for consistent digestive relief, joint comfort and routine inflammation-related benefits is limited or inconclusive.

Format
Tablet
Container
60 Tablet(s)
Per serving
$0.26
Customer rating
4.6 · 2,627 ratings
Report analysis

Goals

Inflammation
Inflammation
Impact
Moderate effect
B+ Ingredient FitF PathwaysC EvidenceA+ Formulation Logic
Study evidence
Bromelain Supportive 12 studies
Gut Health
Gut Health
Impact
Moderate effect
B+ Ingredient FitC PathwaysC- EvidenceA+ Formulation Logic
Bromelain · 500 mg
Study evidence
Bromelain Supportive 2 studies
Joint Health
Joint Health
Impact
Moderate effect
C+ Ingredient FitF PathwaysC EvidenceA+ Formulation Logic
Study evidence

Ingredients

IngredientAmount per servingScore
Calcium (Calcium Carbonate)
 75 mg
Bromelain (Pineapple)
 500 mg 96
Adults 18–50
Report overview
Bromelain (Pineapple) · 500 mg OverallScore96
A+ Composition And Label DisclosureA+ Composition And Label DisclosureB+ Commercial Price And Usability
The serving provides 500 mg of bromelain, with a moderate estimated whole-product cost per 500 mg. The stated activity is 2400 GDU per gram. The bromelain comes from pineapple stem.
How this ingredient is rated

Composition and Label Disclosure100

The stated activity is 2400 GDU per gram.
Enzyme Activity Disclosure
The stated activity is 2400 GDU per gram.
Declared GDU per Gram
The stated activity is 2400 GDU per gram.

Composition and Label Disclosure100

The serving lists 500 mg of bromelain. The bromelain comes from pineapple stem.
Declared Bromelain Mass
The declared serving contains 500 mg of bromelain.
Botanical Source Disclosure
The bromelain comes from pineapple stem.

Commercial Price and Usability80

The estimated whole-product cost per 500 mg of declared bromelain is moderate.
Cost per 500 mg Declared Bromelain
The estimated whole-product cost per 500 mg of declared bromelain is moderate.
View ingredientView products
86 Performance

Bromelain 2400 GDU/g - 500 mg

NOW
Ingredient quality is stronger because the formula provides 500 mg of pineapple bromelain with 2400 GDU/g activity. The focused formula is easy to compare, although it provides no complementary enzymes or botanicals.
83 Performance

High Potency Bromelain 3000 GDU 500 mg

Doctor's Best
Ingredient quality is stronger because the formula provides 500 mg of bromelain with higher activity stated in the product name. The supplied ingredient record does not repeat the activity units, and the single-ingredient design adds no complementary enzymes.
82 Performance

Bromelain 2400 GDU/g 500 mg

Protocol For Life Balance
Ingredient quality is stronger because the formula provides 500 mg of pineapple bromelain with 2400 GDU/g activity. The focused formula is easy to compare, although it provides no complementary enzymes or botanicals.
81 Budget

Bromelain 500 mg

AN Amazing Nutrition Amazing Formulas
The lower-cost serving provides 500 mg of pineapple bromelain in a focused formula. Activity units are not disclosed, so the low cost comes with less potency information.
77 Budget

Bromelain 500 mg

Herbal Secrets
The lower-cost serving provides 500 mg of pineapple bromelain in a very simple formula. Activity units are not disclosed, so its potency evidence is limited.
79 Budget

Bromelain 500 mg

Source Naturals
The lower-cost serving provides 500 mg of bromelain with a small amount of calcium. The bromelain source and activity units are not disclosed.
81 Value

Bromelain 500 mg

The Vitamin Shoppe
The value balance improves because the lower-cost serving provides 500 mg of pineapple bromelain in a focused formula. Activity units are not disclosed, so enzyme strength cannot be compared precisely.
82 Value

Bromelain 500 mg

Natural Factors
The value balance improves because the lower-cost serving provides 500 mg of pineapple-extract bromelain in a simple formula. Activity units are not disclosed, which makes enzyme potency harder to compare.
79 Value

Bromelain 500 mg

Nutricost
The value balance improves because the lower-cost serving provides 500 mg of pineapple bromelain without unrelated active ingredients. Activity units are not disclosed, which limits confidence in potency.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The role of enzyme supplementation in digestive disorders.
    Roxas M · Alternative medicine review : a journal of clinical therapeutic · 2009
    Narrative reviewGut Health forBromelain
  2. Effects of bromelain supplementation on disease activity and quality of life in patients with ulcerative colitis: a randomized, triple-blind, placebo-controlled study.
    Delgarm P; Mokhtare M; Ebrahimi Daryani N; Abolghasemi J; Rahideh ST · Scientific reports · 2025
    Randomized trial70 participantsGut Health forBromelain
  3. Therapeutic efficacy of bromelain in impacted third molar surgery: a randomized controlled clinical study.
    Ordesi P; Pisoni L; Nannei P; Macchi M; Borloni R; Siervo S · Quintessence international (Berlin, Germany : 1985) · 2016
    Randomized trial80 participantsInflammation forBromelain
  4. Efficacy of proteolytic enzyme bromelain on health outcomes after third molar surgery. Systematic review and meta-analysis of randomized clinical trials.
    Mendes ML; do Nascimento-Júnior EM; Reinheimer DM; Martins-Filho PR · Medicina oral, patologia oral y cirugia bucal · 2019
    Meta-analysis6 studies pooledInflammation forBromelain
  5. Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - new evidence on the antiinflammatory mode of action of bromelain.
    Müller S; März R; Schmolz M; Drewelow B; Eschmann K; Meiser P · Phytotherapy research : PTR · 2013
    Randomized trial12 participantsInflammation forBromelain
  6. An Evaluation of the Effects of Pineapple-Extract and Bromelain-Based Treatment after Mandibular Third Molar Surgery: A Randomized Three-Arm Clinical Study.
    Colletti A; Procchio C; Pisano M; Martelli A; Pellizzato M; Cravotto G · Nutrients · 2024
    Randomized trial42 participantsInflammation forBromelain
  7. Therapeutic uses of pineapple-extracted bromelain in surgical care - A review.
    Muhammad ZA; Ahmad T · JPMA. The Journal of the Pakistan Medical Association · 2019
    Narrative reviewInflammation forBromelain
  8. Bromelain as a Treatment for Osteoarthritis: a Review of Clinical Studies.
    Brien S; Lewith G; Walker A; Hicks SM; Middleton D · Evidence-based complementary and alternative medicine : eCAM · 2024
    Narrative reviewJoint Health forBromelain
  9. Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis.
    Kasemsuk T; Saengpetch N; Sibmooh N; Unchern S · Clinical rheumatology · 2017
    Randomized trial40 participantsJoint Health forBromelain
  10. Oral enzyme combination therapy reduces systemic inflammation, urinary CTXII and pain in knee osteoarthritis: a proof-of-mechanism, randomised, crossover, double-blind, placebo-controlled trial.
    Henrotin Y; Pap T; Lieten S; Badot V; Dubuc JE; Urbin-Choffray D; von Eynatten M; Johansen OE; Rau S; Brabants K · RMD open · 2025
    Randomized trial45 participantsJoint Health forBromelain
  11. Efficacy, tolerability, and safety of an oral enzyme combination vs diclofenac in osteoarthritis of the knee: results of an individual patient-level pooled reanalysis of data from six randomized controlled trials
    Ueberall MA, Mueller-Schwefe GH, Wigand R, Essner U · Journal of Pain Research · 2016
    Meta-analysis697 participants6 studies pooledJoint Health forBromelain
  12. The safety and efficacy of an enzyme combination in managing knee osteoarthritis pain in adults: a randomized, double-blind, placebo-controlled trial
    Bolten WW, Glade MJ, Raum S, Ritz BW · Arthritis · 2015
    Randomized trial150 participantsJoint Health forBromelain