$27.00 $0.45 per serving
Product analysis
Active B12 with L-5-MTHF combines nutrients that can help with tiredness and concentration when low intake is the cause. Extra energy or productivity is not established once nutritional needs are met.
AI assessment of the formula, label and price. How scoring works
Nutrient Quality40
The named folate and B12 forms are clearly identified, but their quality cannot be judged confidently. The names alone do not establish better absorption or stronger benefits.
Ingredient Transparency80
The nutrient amounts and forms are disclosed, making the formula straightforward to compare. The split between the B12 forms is missing.
Value For Money40
Value for money cannot be determined confidently. The available comparisons do not establish whether the folate and B12 justify the serving cost.
Customer Satisfaction89
Customer feedback is very favorable across thousands of ratings. The broad review base supports the satisfaction pattern without proving an energy benefit.
Product Focus75
The two-nutrient formula stays focused on related nutritional needs. Its clearest role is correcting low intake that affects blood formation, tiredness or concentration.
- Format
Lozenge - Container
- 60 Liquid(s)
- Per serving
- $0.45
- Customer rating
- 4.8 · 3,664 ratings
Goals
Impact
Highest effect
Folate · 1360 mcg DFEVitamin B12 · 1000 mcg
Impact
High effect
Ingredients
| Ingredient | Amount per serving | Score |
|---|---|---|
Folate (Quatrefolic (6S)-5-Methyltetrahydrofolate, Glucosamine Salt) | 1360 mcg DFE | |
Vitamin B12 (Adenosylcobalamin, Mecobalactive) | 1000 mcg |
Vitamin B12 (Adenosylcobalamin, Mecobalactive) · 1000 mcg OverallScore51
A serving provides 1000 mcg of B12 at a moderate cost for that amount, based on the full serving price. Adenosylcobalamin is named, but another source and the proportions are unknown. The full serving price can overstate the cost attributable to B12.
How this ingredient is rated
Active Ingredient Quality & Bioavailability20
Adenosylcobalamin is named, but another B12 source and the proportions are unknown.
Bioactive B12 Form Selection
Adenosylcobalamin is named, but another B12 source and the proportions are unknown.
Dose, Safety & Label Transparency85
The serving lists 1000 mcg of B12. Adenosylcobalamin is named, but another source and the proportions are unknown.
Therapeutic Dosage Level
Each serving provides 1000 mcg of B12.
Label and Form Transparency
The total and adenosylcobalamin are listed, but another source and individual amounts are unknown.
Value45
The cost is moderate for the amount of B12, based on the full serving price; that can overstate the cost attributable to B12.
Price per 1,000 mcg B12
The cost is moderate for the amount of B12, based on the full serving price; that can overstate the cost attributable to B12.
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Sources
Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
- The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
- Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
- The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
- Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
- Oral Vitamin B12 versus Placebo for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Gynecological Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial.
- Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial.
- A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.
- Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
- The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.
- Hair Loss After Metabolic and Bariatric Surgery: a Systematic Review and Meta-analysis.
- Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.
- Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer.
- Role of oxaliplatin combined with 5-fluorouracil and folinic acid in the first- and second-line treatment of advanced colorectal cancer.
- Phase I-II study of vinorelbine in combination with 5-fluorouracil and folinic acid as first-line chemotherapy in metastatic breast cancer: a regimen with a low subjective toxic burden.
- Factors Associated with Premature Hair Graying in a Young Indian Population.
- Risk Factors for Pediatric Alopecia Areata: Clinical and Biochemical Findings from a Case - Control Study.
- Hair Loss After Laparoscopic Sleeve Gastrectomy.
- Demographic Characteristics and Association of Serum Vitamin B12, Ferritin and Thyroid Function with Premature Canities in Indian Patients from an Urban Skin Clinic of North India: A Retrospective Analysis of 71 Cases.