SAMe 200 mg

SAMe 200 mg

Natural Factors4.6 (651 ratings)
Format:Tablet Quantity: 60 Tablet(s) · 60 servings
Goals
$34.97 $0.58 per serving

Product analysis

49 out of 100

SAMe 200 mg offers a compound involved in normal metabolism, with limited value for the serving cost.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality20

The SAMe form is not specified, limiting a confident quality comparison. The available information does not establish poor ingredient quality.

Ingredient Transparency63

The amount is disclosed, helping you compare servings. The form is omitted, so the preparation remains unclear.

Value For Money40

SAMe offers limited value for the amount supplied. The cost comparison does not establish a practical benefit from the serving.

Customer Satisfaction77

Customer feedback is positive across several hundred ratings. No specific customer experiences are described.

Product Focus72

The formula stays focused on SAMe and its role in normal metabolism. That role does not establish routine toxin clearance or a general detox benefit.

Format
Tablet
Container
60 Tablet(s)
Per serving
$0.58
Customer rating
4.6 · 651 ratings
Report analysis

Goals

Liver & Detox
Impact
High effect
B+ Ingredient FitF PathwaysA- EvidenceA+ Formulation Logic
SAMe · 200 mg
Study evidence
SAMe Supportive 30 studies

Ingredients

IngredientAmount per servingScore
SAMe
200 mg 74
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
SAMe · 200 mg OverallScore74
B Active Ingredient Quality & BioavailabilityA- Dose, Safety & Label TransparencyD- Value
200 mg of SAMe per serving comes at a limited cost for the amount. The source includes S-Adenosyl-L-Methionine Tosylate Disulfate, but its proportion is unclear. Moisture protection from blister packaging is unclear. The active amount is disclosed.
How this ingredient is rated

Active Ingredient Quality & Bioavailability77

The SAMe source includes S-Adenosyl-L-Methionine Tosylate Disulfate; its share is not stated. Blister packaging is not documented, leaving moisture protection unclear.
Stabilized Salt Form
The SAMe source includes S-Adenosyl-L-Methionine Tosylate Disulfate; its share is not stated.
Packaging Integrity
Blister packaging is not documented, leaving moisture protection unclear.

Dose, Safety & Label Transparency88

The serving lists 200 mg of SAMe. The active SAMe amount is stated separately from its salt.
Active Dosage Strength
The serving lists 200 mg of SAMe.
Net SAMe Yield Transparency
The active SAMe amount is stated separately from its salt.

Value40

The cost for the listed SAMe amount is limited by uncertainty about protective release. Enteric coating or delayed release is not documented.
Price Per 400mg Active Dose
The cost for the listed SAMe amount is limited by uncertainty about protective release. Enteric coating or delayed release is not documented.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Early treatment efficacy of S-adenosylmethionine in patients with intrahepatic cholestasis: A systematic review.
    Noureddin M; Sander-Struckmeier S; Mato JM · World journal of hepatology · 2020
    Systematic review9 studies pooledLiver & Detox forSAMe
  2. Ursodeoxycholic acid and S-adenosylmethionine in the treatment of intrahepatic cholestasis of pregnancy: a multi-centered randomized controlled trial.
    Zhang L; Liu XH; Qi HB; Li Z; Fu XD; Chen L; Shao Y · European review for medical and pharmacological sciences · 2016
    Randomized trial120 participantsLiver & Detox forSAMe
  3. S-adenosyl-L-methionine for the treatment of chronic liver disease: a systematic review and meta-analysis.
    Guo T; Chang L; Xiao Y; Liu Q · PloS one · 2015
    Meta-analysis705 participants11 studies pooledLiver & Detox forSAMe
  4. Protective effect of S-adenosylmethionine on hepatic ischemia-reperfusion injury during hepatectomy in HCC patients with chronic HBV infection.
    Liu GY; Wang W; Jia WD; Xu GL; Ma JL; Ge YS; Yu JH; Sun QK; Meng FL · World journal of surgical oncology · 2014
    Non-randomized trial81 participantsLiver & Detox forSAMe
  5. S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial.
    Mato JM; Cámara J; Fernández de Paz J; Caballería L; Coll S; Caballero A; García-Buey L; Beltrán J; Benita V; Caballería J; Solà R; Moreno-Otero R; Barrao F; Martín-Duce A; Correa JA; Parés A; Barrao E; García-Magaz I; Puerta JL; Moreno J; Boissard G; Ortiz P; Rodés J · Journal of hepatology · 1999
    Randomized trial123 participantsLiver & Detox forSAMe