Lion's Mane 500 mg

Lion's Mane 500 mg

NOW4.7 (3,756 ratings)
Format:Capsule Quantity: 60 Capsule(s) · 30 servings
Goals

Product analysis

56 out of 100

Lion's Mane 500 mg offers a focused mushroom supplement with preliminary support for some aspects of thinking. Its preparation is not specified, so the results from particular researched preparations may not apply.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality20

The mushroom preparation is not disclosed. That makes it difficult to compare its quality with clearly described extracts or other mushroom preparations.

Ingredient Transparency63

The mushroom amount is disclosed. The preparation remains unspecified, limiting how closely it can be compared with alternatives.

Value For Money80

The labeled serving looks favorable for value. The unclear preparation still limits comparisons with other lion’s mane options.

Customer Satisfaction88

Buyer ratings are positive across a large number of reviews. That supports a positive picture of satisfaction, while reviews do not establish health benefits.

Product Focus58

The single mushroom ingredient keeps the formula focused on cognitive support. Evidence is preliminary and depends on the preparation, so broad memory benefits remain uncertain.

Format
Capsule
Container
60 Capsule(s)
Per serving
$0.40
Customer rating
4.7 · 3,756 ratings
Report analysis

Goals

Brain Health
Impact
High effect
A Ingredient FitD+ PathwaysB- EvidenceA+ Formulation Logic

Lion’s mane has preliminary human cognitive research with mixed task findings. A small young-adult pilot used a particular preparation, so this product’s mushroom amount does not establish equivalent exposure or effects. Fruiting-body, mycelium and extract materials cannot be assumed interchangeable, and the supplied findings do not establish human nerve growth or prevention of cognitive decline.

How this product is rated for Brain Health

Ingredient fit95

The relevant ingredients give the formula a direct brain-health focus, though its stated uses span other goals.
Goal fit
The relevant ingredients give the formula a direct brain-health focus, though its stated uses span other goals.
Dose adequacy
The declared amounts fully meet the supplied exposure comparison, without establishing universal benefit or a daily regimen.

Pathways51

The strongest represented mechanism is oxidative and inflammatory protection, with the relevant ingredient limitations still applying.
Depth
The strongest represented mechanism is oxidative and inflammatory protection, with the relevant ingredient limitations still applying.
Breadth
The contribution concentrates on one mechanism, limiting breadth across different aspects of brain function.

Evidence72

Hericium mushroom leads the evidence finding, within the supplied population and outcome limitations.
Evidence strength
Hericium mushroom leads the evidence finding, within the supplied population and outcome limitations.
Studied preparation
The relevant preparations are accepted in the supplied comparison; this does not remove limitations in the underlying cognitive findings.

Formulation logic100

The relevant ingredients work independently or have the required partner. No configured conflict is identified in the supplied ingredient findings.
Partner coverage
The relevant ingredients work independently or have the required partner.
Conflicts
No configured conflict is identified in the supplied ingredient findings.
Effective doses
The included ingredients meet the minimum amount comparison; that threshold does not establish a proven cognitive dose.
Study evidence
Cognitive Support
Impact
Highest effect
A Ingredient FitC- PathwaysB+ EvidenceA+ Formulation Logic
Hericium mushroom · 1000 mg

Hericium mushroom has preliminary relevance to selected cognitive tasks, but the small young-adult study used a specific mushroom complex. The declared 1000 mg serving receives full amount recognition in the saved findings, while generic mushroom material cannot be assumed equivalent to that preparation. Evidence does not establish broad memory improvement or brain regeneration.

How this product is rated for Cognitive Support

Ingredient fit95

Hericium mushroom supply the main recorded connections, subject to their specific evidence and amount limits.
Goal fit
The relevant ingredients are concentrated on this goal, though the product is also linked to other uses.
Dose adequacy
The included amounts fully meet the saved comparison, without establishing a proven benefit at those amounts.

Pathways59

The strongest recorded connection is synaptic structure and plasticity, with the ingredient-specific limits described above. The qualifying contribution is concentrated in one pathway, giving limited breadth across the listed mechanisms.
Depth
The strongest recorded connection is synaptic structure and plasticity, with the ingredient-specific limits described above.
Breadth
The qualifying contribution is concentrated in one pathway, giving limited breadth across the listed mechanisms.

Evidence85

Hericium leads the saved comparison, but its specific-complex pilot findings cannot establish generic mushroom equivalence. Preparation recognition does not remove those scientific limits.
Evidence strength
Hericium leads the saved comparison, but its specific-complex pilot findings cannot establish generic mushroom equivalence.
Studied preparation
The saved findings recognize the included preparations; this does not extend the populations or outcomes supported by their evidence.

Formulation logic100

No configured ingredient conflict was identified in the supplied findings. No missing partner is identified for the included contributors.
Partner coverage
The included contributors do not require a missing partner in the supplied findings; this does not establish added benefit from combining them.
Conflicts
No configured ingredient conflict was identified in the supplied findings.
Effective doses
The included contributors meet the saved minimum amount requirement, which is not a proven effective-dose threshold.
Study evidence
Productivity Boost
Impact
Lower effect
A Ingredient FitF PathwaysD- EvidenceA+ Formulation Logic
Study evidence
Mental Focus
Impact
Lower effect
A Ingredient FitF PathwaysF EvidenceA+ Formulation Logic
Study evidence

Ingredients

IngredientAmount per servingScore
Lions Mane Mushroom, Powder
1000 mg 36
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Organic Vegetarian
Report overview
F Composition And Label DisclosureD+ Composition And Label DisclosureB+ Commercial Price And Usability
A serving lists 1000 mg of hericium mushroom. The whole-product serving costs about $0.41.
How this ingredient is rated

Composition and Label Disclosure0

The preparation is unavailable in the saved details. Beta-glucan and polysaccharide details are unavailable in the saved information.
Marker and Preparation Disclosure
Beta-glucan and polysaccharide details are unavailable in the saved information.

Composition and Label Disclosure50

The saved amount is 1000 mg of hericium mushroom per serving.
Hericium Target Amount Disclosure
The hericium amount is recorded as 1000 mg per serving.

Commercial Price and Usability80

A whole-product serving costs about $0.41; this is the price for the entire serving.
Commercial Price per Labeled Serving
The whole-product serving costs about $0.41.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Acute Effects of Naturally Occurring Guayusa Tea and Nordic Lion's Mane Extracts on Cognitive Performance.
    La Monica MB; Raub B; Ziegenfuss EJ; Hartshorn S; Grdic J; Gustat A; Sandrock J; Ziegenfuss TN · Nutrients · 2023
    Randomized trialBrain Health Productivity Boost forHericium mushroom
  2. Improvement of cognitive functions by oral intake of Hericium erinaceus.
    Saitsu Y; Nishide A; Kikushima K; Shimizu K; Ohnuki K · Biomedical research (Tokyo, Japan) · 2020
    Randomized trialBrain Health Cognitive Support forHericium mushroom
  3. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial.
    Mori K; Inatomi S; Ouchi K; Azumi Y; Tuchida T · Phytotherapy research : PTR · 2009
    Randomized trial30 participantsBrain Health Cognitive Support forHericium mushroom
  4. A review of the effects of mushrooms on mood and neurocognitive health across the lifespan.
    Cha S; Bell L; Shukitt-Hale B; Williams CM · Neuroscience and biobehavioral reviews · 2024
    Systematic review34 studies pooledBrain Health forHericium mushroom
  5. Acute effects of a standardised extract of Hericium erinaceus (Lion's Mane mushroom) on cognition and mood in healthy younger adults: a double-blind randomised placebo-controlled study.
    Surendran G; Saye J; Binti Mohd Jalil S; Spreadborough J; Duong K; Shatwan IM; Lilley D; Heinrich M; Dodd GF; Surendran S · Frontiers in nutrition · 2025
    Randomized trial18 participantsBrain Health Mental Focus forHericium mushroom
  6. Prevention of Early Alzheimer's Disease by Erinacine A-Enriched Hericium erinaceus Mycelia Pilot Double-Blind Placebo-Controlled Study.
    Li IC; Chang HH; Lin CH; Chen WP; Lu TH; Lee LY; Chen YW; Chen YP; Chen CC; Lin DP · Frontiers in aging neuroscience · 2024
    Randomized trialCognitive Support forHericium mushroom
  7. Benefits, side effects, and uses of Hericium erinaceus as a supplement: a systematic review.
    Menon A; Jalal A; Arshad Z; Nawaz FA; Kashyap R · Frontiers in nutrition · 2025
    Systematic review26 studies pooledCognitive Support forHericium mushroom
  8. The Acute and Chronic Effects of Lion's Mane Mushroom Supplementation on Cognitive Function, Stress and Mood in Young Adults: A Double-Blind, Parallel Groups, Pilot Study.
    Docherty S; Doughty FL; Smith EF · Nutrients · 2023
    Randomized trial41 participantsCognitive Support forHericium mushroom
  9. Four Weeks of Hericium erinaceus Supplementation Does Not Impact Markers of Metabolic Flexibility or Cognition.
    Grozier CD; Alves VA; Killen LG; Simpson JD; O'Neal EK; Waldman HS · International journal of exercise science · 2025
    Non-randomized trial24 participantsProductivity Boost forHericium mushroom