Brain Health

Mental & Cognitive Health

Promoting cognitive function, memory, and overall brain health; increasingly prioritized, especially in older adults.

Best effective

Acetyl L-Carnitine
Other
Studies suggest that Acetyl-L-Carnitine may have neuroprotective effects and could improve cognitive performance, particularly in older adults or those with cognitive decline. It may also support memory and learning processes.
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Alpha-GPC
Other
Alpha-GPC supplementation supports the production of acetylcholine, a neurotransmitter involved in memory, learning, and focus. Studies indicate potential benefits in cognitive performance and neurological health.
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Bacopa
Botanical
Studies and user experiences suggest Bacopa may improve memory, learning, and overall cognitive function, especially after consistent use. Bacopa contains compounds that may protect brain cells and promote neurotransmitter activity.
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Choline
Vitamin
Choline's role in producing acetylcholine directly impacts cognitive functions, and supplementation can improve these functions, particularly in cases of deficiency.
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Hericium mushroom
Botanical
Studies indicate Hericium mushrooms may enhance cognitive abilities and memory by promoting nerve growth factor (NGF). This is based on the observation that Hericium mushrooms have compounds that stimulate NGF production, a vital process for neuron health and survival.
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Huperzine
Other
Huperzine A's mechanism of action directly impacts acetylcholine levels, a key neurotransmitter for cognitive processes. Studies show improvements in memory and cognitive performance with Huperzine A supplementation, particularly in individuals with cognitive decline. It acts as a neuroprotectant by shielding nerve cells from glutamate-induced excitotoxicity.
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Vinpocetine
Other
Studies suggest Vinpocetine may improve cerebral blood flow and enhance cognitive functions such as memory and focus. It is believed to act as a vasodilator, promoting better oxygen and nutrient delivery to the brain.
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Very effective

Acetyl-L-Carnitine
Other
Studies suggest ALCAR can enhance mitochondrial function in the brain, providing more energy to neurons. It also contributes to the synthesis of acetylcholine, a neurotransmitter crucial for learning and memory. Some research indicates benefits in age-related cognitive decline.
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Deanol
Other
Deanol is believed to increase the levels of acetylcholine in the brain by converting to choline. Acetylcholine is a key neurotransmitter that plays a significant role in memory, learning, and concentration. Supplementation with Deanol has been associated with improvements in focus and mental acuity in some individuals. However, more research is needed to confirm these effects.
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EPA (Eicosapentaenoic Acid)
Fatty Acid
EPA contributes to the structural integrity of brain cells. Research indicates it can positively influence cognitive processes, particularly memory and focus. Furthermore, it may play a role in regulating neurotransmitters, thus affecting mood stability.
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Fish Oil
Fatty Acid
DHA is a major structural fat in the brain and is vital for brain development and function throughout life. Supplementation can support memory, learning, and overall cognitive performance, particularly in aging individuals.
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Folate
Vitamin
Folate has been linked to supporting brain health and cognitive function, playing a role in neurotransmitter synthesis and protecting against cognitive impairment. Especially important during pregnancy and early life, but it can be beneficial for adults as well.
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Ginkgo
Botanical
Studies have shown that Ginkgo Biloba can improve blood flow to the brain, which can enhance cognitive function, memory, and mental clarity. The effect is particularly noted in individuals experiencing age-related cognitive decline.
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Glutamic Acid
Amino Acid
Glutamic acid plays a crucial role in neural signaling, learning, and memory processes within the brain. It is the primary excitatory neurotransmitter, facilitating communication between neurons. Supplementation could support cognitive function, but it's essential to recognize that excess glutamic acid can have neurotoxic effects. Therefore, careful dosage and monitoring are necessary.
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Iodine
Mineral
Iodine plays a critical role in the synthesis of thyroid hormones, which are crucial for normal brain development and cognitive function throughout life. Adequate iodine intake is especially important during pregnancy and infancy, as deficiencies can lead to impaired cognitive development. Consistent iodine intake can support brain health and cognitive performance.
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Lithium
Mineral
Research suggests that lithium can promote the growth of new neurons in the brain and protect against neurodegeneration. It has been shown to have a positive effect on cognitive decline and may offer benefits for individuals with brain conditions. However, more research is needed.
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Omega-3
Fatty Acid
DHA is crucial for brain development and function, impacting memory, learning, and overall cognitive performance.
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Rosemary
Botanical
Studies indicate that rosemary can improve memory recall and cognitive performance. Compounds in rosemary have been shown to protect against neurodegeneration and support healthy brain function by increasing blood flow.
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Thiamin
Vitamin
Thiamin deficiency can lead to neurological issues such as confusion, irritability, and impaired memory. Maintaining sufficient thiamin levels supports the structural and functional integrity of the nervous system. Studies indicate that supplementing thiamin can help improve cognitive performance in those with deficiencies.
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Tyrosine
Amino Acid
Studies suggest tyrosine can improve cognitive performance, especially during stressful situations by aiding the production of neurotransmitters necessary for mental clarity and focus.
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Vitamin B12
Vitamin
B12 is important for the myelin sheath which protects nerve cells. A deficiency can lead to cognitive decline, memory issues, and neurological problems. Studies show that adequate B12 levels can support overall cognitive function, especially in older adults or those with deficiency.
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Vitamin B6
Vitamin
B6 participates in the formation of several neurotransmitters which play important roles in mood and cognition. It has been associated with improved mental health and cognitive ability in some studies.
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Decently effective

Glycine
Amino Acid
Glycine is involved in the production of neurotransmitters, and studies suggest that it can improve some aspects of cognitive function, particularly memory and focus.
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Phenylalanine
Amino Acid
Phenylalanine's role in neurotransmitter synthesis suggests its potential in supporting various cognitive functions. However, its efficacy might be more noticeable when deficiencies are present, and should be combined with a healthy diet.
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Taurine
Amino Acid
Taurine can act as an antioxidant and anti-inflammatory agent in the brain, potentially reducing damage from oxidative stress and inflammation. It also has a role in neurotransmitter function, which can contribute to cognitive health and focus.
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Theanine
Amino Acid
Studies have explored L-theanine's ability to improve certain aspects of cognitive function, including attention and memory, along with its potential antioxidant and neuroprotective effects.
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Partially effective

Apigenin
Other
Studies suggest that apigenin can cross the blood-brain barrier and exert antioxidant and anti-inflammatory effects. These actions may contribute to improved cognitive function and protection against neurodegenerative diseases.
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Boron
Mineral
Some studies show improved cognitive function with boron supplementation, indicating its potential for enhancing brain health.
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Carnosine
Other
Carnosine's antioxidant and anti-glycation effects may contribute to its neuroprotective properties, potentially benefiting cognitive function.
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Creatine
Other
Creatine is involved in providing energy to the brain. It can improve cognitive functions by increasing creatine levels in the brain. Some studies have found that creatine supplementation can improve memory and intelligence.
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Green Tea
Botanical
Green tea's L-theanine and caffeine work synergistically to enhance focus and alertness. Studies have also linked regular green tea consumption with a lower risk of cognitive decline.
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Luteolin
Other
Research suggests that luteolin can cross the blood-brain barrier and exert antioxidant and anti-inflammatory effects, which may help protect neurons from damage. It could potentially improve memory and learning in some contexts.
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