Optimized Resveratrol

Optimized Resveratrol

Life Extension4.7 (4,341 ratings)
Format:Capsule Quantity: 60 Capsule(s) · 60 servings
Goals
$26.25 $0.43 per serving

Product analysis

58 out of 100

Optimized Resveratrol combines resveratrol with other plant compounds, with limited and mixed evidence for circulation and cognitive support. An undisclosed botanical blend makes the full formula harder to assess.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality39

Several plant sources or forms are named, but their absorption quality cannot be compared confidently. An unidentified botanical blend also prevents a complete quality judgment.

Ingredient Transparency73

Amounts are disclosed for the listed ingredients, and most forms are named. The botanical blend does not identify its individual components, leaving the full makeup unclear.

Value For Money63

The serving is reasonably priced for its declared resveratrol content. Quercetin cannot be compared reliably for value, so the price case rests mainly on resveratrol.

Customer Satisfaction88

Customers give very positive ratings across a substantial review base. The ratings do not reveal which health effects, if any, customers experienced.

Product Focus40

Resveratrol anchors a formula aimed at several aging-related and circulation goals, but the human findings are limited and mixed. Unidentified blend contents further limit a complete assessment.

Format
Capsule
Container
60 Capsule(s)
Per serving
$0.43
Customer rating
4.7 · 4,341 ratings
Report analysis

Goals

Inflammation
Impact
Moderate effect
B- Ingredient FitF PathwaysC EvidenceA+ Formulation Logic
Study evidence
Cardiovascular Support
Impact
Moderate effect
B Ingredient FitF PathwaysD+ EvidenceA+ Formulation Logic
Study evidence
Longevity
Impact
Moderate effect
B Ingredient FitC PathwaysD+ EvidenceA+ Formulation Logic
Study evidence
Skin Health
Impact
High effect
B- Ingredient FitC- PathwaysB+ EvidenceA+ Formulation Logic
Resveratrol · 250 mg
Study evidence
Metabolism Support
Impact
High effect
B- Ingredient FitC- PathwaysB+ EvidenceA+ Formulation Logic
Resveratrol · 250 mg
Study evidence

Ingredients

IngredientAmount per servingScore
Trans-Resveratrol (Japanese Knotweed)
250 mg 86
Quercetin (Quercetin Dihydrate)
150 mg
Grape and Wild Blueberry blend
85 mg
Fisetin (Wax Tree extract)
10 mg
Gluten Free Adults 18–50
Report overview
B Composition And Label DisclosureA+ Composition And Label DisclosureB Commercial Price And Usability
The serving states 250 mg trans-resveratrol. The whole-product cost relative to that amount is moderate. The concentration and source are not specified.
How this ingredient is rated

Composition and Label Disclosure77

The trans form is named. The trans-resveratrol concentration is unknown.
Explicit Label Detail
The label identifies the trans form of resveratrol.
Trans-Resveratrol Concentration Disclosure
No trans-resveratrol concentration is available.

Composition and Label Disclosure100

The serving states 250 mg trans-resveratrol.
Resveratrol Amount Disclosure
The trans-resveratrol amount is 250 mg per serving.

Commercial Price and Usability75

The whole-product cost relative to the trans-resveratrol amount is moderate.
Cost per 250 mg Declared Trans-Resveratrol
The cost for the declared trans-resveratrol amount is moderate.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Consumption of a grape extract supplement containing resveratrol decreases oxidized LDL and ApoB in patients undergoing primary prevention of cardiovascular disease: a triple-blind, 6-month follow-up, placebo-controlled, randomized trial.
    Tomé-Carneiro J; Gonzálvez M; Larrosa M; García-Almagro FJ; Avilés-Plaza F; Parra S; Yáñez-Gascón MJ; Ruiz-Ros JA; García-Conesa MT; Tomás-Barberán FA; Espín JC · Molecular nutrition & food research · 2012
    Randomized trial75 participantsCardiovascular Support forResveratrol
  2. Resveratrol improves lipid profile and recovers heart function in postoperative CABG patients.
    Ahmadi P; Akbarzadeh S; Alizadeh M; Mohammadi N; Mahmoodi M; Amini A; Netticadan T; Rezaei M; Movahed A · Molecular and cellular biochemistry · 2025
    Randomized trial60 participantsCardiovascular Support forResveratrol
  3. Resveratrol Supplementation and its Potential Benefits in Obesity-related Non-communicable Diseases.
    Shen CY; Li CP; Yu JT; Ho YJ; Tsai RY · In vivo (Athens, Greece) · 2026
    Meta-analysis2,551 participants40 studies pooledCardiovascular Support forResveratrol
  4. Chronic resveratrol consumption improves brachial flow-mediated dilatation in healthy obese adults.
    Wong RH; Berry NM; Coates AM; Buckley JD; Bryan J; Kunz I; Howe PR · Journal of hypertension · 2014
    Randomized trial28 participantsCardiovascular Support forResveratrol
  5. Effect of resveratrol supplementation on lipid profile in subjects with dyslipidemia: A randomized double-blind, placebo-controlled trial.
    Simental-Mendía LE; Guerrero-Romero F · Nutrition (Burbank, Los Angeles County, Calif.) · 2020
    Randomized trial71 participantsCardiovascular Support forResveratrol
  6. Role of resveratrol supplementation in regulation of glucose hemostasis, inflammation and oxidative stress in patients with diabetes mellitus type 2: A randomized, placebo-controlled trial.
    Mahjabeen W; Khan DA; Mirza SA · Complementary therapies in medicine · 2022
    Randomized trial110 participantsInflammation forResveratrol
  7. Resveratrol decreases local inflammatory markers and systemic endotoxin in patients with aggressive periodontitis.
    Zhang Q; Xu S; Xu W; Zhou Y; Luan H; Wang D · Medicine · 2022
    Randomized trial160 participantsInflammation forResveratrol
  8. Effects of resveratrol supplementation on inflammatory markers, fatigue scale, fasting blood sugar and lipid profile in relapsing-remitting multiple sclerosis patients: a double-blind, randomized placebo-controlled trial.
    Keramatzadeh S; Hosseini SA; Majdinasab N; Cheraghian B; Zilaee M · Nutritional neuroscience · 2025
    Randomized trial55 participantsInflammation forResveratrol
  9. One-year consumption of a grape nutraceutical containing resveratrol improves the inflammatory and fibrinolytic status of patients in primary prevention of cardiovascular disease.
    Tomé-Carneiro J; Gonzálvez M; Larrosa M; Yáñez-Gascón MJ; García-Almagro FJ; Ruiz-Ros JA; García-Conesa MT; Tomás-Barberán FA; Espín JC · The American journal of cardiology · 2012
    Randomized trial75 participantsInflammation forResveratrol
  10. Effects of resveratrol supplementation on risk factors of non-communicable diseases: A meta-analysis of randomized controlled trials.
    Guo XF; Li JM; Tang J; Li D · Critical reviews in food science and nutrition · 2019
    Meta-analysis1,069 participants29 studies pooledInflammation forResveratrol
  11. Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults.
    Witte AV; Kerti L; Margulies DS; Flöel A · The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014
    Randomized trial46 participantsLongevity forResveratrol
  12. Effects of resveratrol on memory performance, hippocampus connectivity and microstructure in older adults - A randomized controlled trial.
    Huhn S; Beyer F; Zhang R; Lampe L; Grothe J; Kratzsch J; Willenberg A; Breitfeld J; Kovacs P; Stumvoll M; Trampel R; Bazin PL; Villringer A; Witte AV · NeuroImage · 2019
    Randomized trial60 participantsLongevity forResveratrol
  13. Resveratrol levels and all-cause mortality in older community-dwelling adults.
    Semba RD; Ferrucci L; Bartali B; Urpí-Sarda M; Zamora-Ros R; Sun K; Cherubini A; Bandinelli S; Andres-Lacueva C · JAMA internal medicine · 2014
    Cohort study783 participantsLongevity forResveratrol
  14. Impact of Resveratrol Supplementation on Human Sirtuin 1: A Grading of Recommendations Assessment, Development and Evaluation-Assessed Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.
    Mansouri F; Feliziani G; Bordoni L; Gabbianelli R · Journal of the Academy of Nutrition and Dietetics · 2025
    Meta-analysis11 studies pooledLongevity forResveratrol
  15. Trans-resveratrol reduces visible signs of skin ageing in healthy adult females over 40: an 8-week randomized placebo-controlled trial.
    Rao A; Briskey D; Roche G; Tremblay A; Da Silva Pinto M; Tompkins TA · Frontiers in aging · 2026
    Randomized trial134 participantsLongevity Skin Health forResveratrol
  16. Effects of resveratrol on glucose control and insulin sensitivity in subjects with type 2 diabetes: systematic review and meta-analysis.
    Zhu X; Wu C; Qiu S; Yuan X; Li L · Nutrition & metabolism · 2022
    Meta-analysis283 participants9 studies pooledMetabolism Support forResveratrol
  17. Effects of resveratrol supplementation on multiple health outcomes: an umbrella review of systematic reviews and meta-analyses of randomized controlled trials.
    Sun JN; Yang R; Fang L; Li YJ; Xing WY; Sun ML; Wu L; Wu QJ; Gong TT · Nutrition journal · 2026
    Meta-analysis45 studies pooledMetabolism Support forResveratrol
  18. Resveratrol improves insulin resistance, glucose and lipid metabolism in patients with non-alcoholic fatty liver disease: a randomized controlled trial.
    Chen S; Zhao X; Ran L; Wan J; Wang X; Qin Y; Shu F; Gao Y; Yuan L; Zhang Q; Mi M · Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 2015
    Randomized trial60 participantsMetabolism Support forResveratrol
  19. Supplementation with resveratrol modified gut microbiota improving insulin sensitivity and lipid metabolism in subjects with obesity and insulin resistance.
    Guevara-Cruz M; Sánchez-Tapia M; Velazquez-Villegas LA; Torre-Villalvazo I; Guizar-Heredia R; Godínez-Salas E; López-Barradas A; Granados O; Torres-Villalobos G; Torres N; Tovar AR · European journal of nutrition · 2026
    Randomized trial32 participantsMetabolism Support forResveratrol
  20. Efficacy of Resveratrol Supplementation on Glucose and Lipid Metabolism: A Meta-Analysis and Systematic Review.
    Zhou Q; Wang Y; Han X; Fu S; Zhu C; Chen Q · Frontiers in physiology · 2022
    Meta-analysis1,171 participants25 studies pooledMetabolism Support forResveratrol