Resveratrol

Description

Resveratrol is a naturally occurring stilbenoid, a type of polyphenol, predominantly found in the skins of red grapes, various berries, peanuts, and Japanese knotweed. It is part of a plant's defense system against stress and pathogens. Its presence in red wine has contributed to the concept of the 'French paradox', linking moderate red wine consumption to cardiovascular benefits. This powerful compound functions primarily as an antioxidant, helping to protect the body's cells from damage caused by oxidative stress and free radicals. Beyond its antioxidant capacity, resveratrol also exhibits anti-inflammatory effects and can modulate various cellular pathways, including those involved in metabolism and longevity. As a dietary supplement, resveratrol is commonly used to support overall cardiovascular health by promoting healthy blood flow and maintaining arterial integrity. It is also investigated for its potential role in neuroprotection and supporting healthy aging by influencing cellular repair and regeneration processes.

Sources
Red grapes (especially skins)Red winePeanutsBlueberriesCranberriesRaspberriesJapanese knotweed
Cheapest Resveratrol supplements
Discover the cheapest Resveratrol supplements offering powerful antioxidant support for heart health, anti-aging, cognitive function, and overall well-being.
best Resveratrol supplements
Explore top-rated Resveratrol supplements known for their powerful antioxidant properties, supporting anti-aging, heart and cognitive health, and overall well-being.
Value Resveratrol supplements
Compare top Resveratrol supplements to find the best value for your health goals, including heart health, anti-aging, and cognitive support.
Timing & Intake
AnytimeWith foodTake with A source of fat to enhance absorption, as it is fat-soluble.
Optimal Dosage
Minimum100 mg
Maximum500 mg
Safety & Toxicity
Goals
Cognitive Support
Cognitive Support
Impact
High effect
Typical dose:100–500 mg
Resveratrol's benefits for brain circulation and its antioxidant properties are well-supported. The current priority of 0 is an error. It should be ranked as a strong supportive supplement, similar in impact to Ginkgo.
View goal ->
Metabolism Boost
Metabolism Boost
Impact
High effect
Typical dose:100–500 mg
Resveratrol has been shown to increase the number and efficiency of mitochondria, the cellular powerhouses where fuel is burned. By activating the SIRT1 gene, it can improve glucose homeostasis and increase fatty acid oxidation, effectively making cellular energy production more robust and efficient.
View goal ->
Skin Health
Skin Health
Impact
High effect
Typical dose:100–500 mg
Resveratrol activates sirtuins, proteins associated with cellular longevity, and provides powerful antioxidant protection against free radical damage from sun exposure and pollution. This helps to preserve collagen and elastin, reducing signs of premature aging.
View goal ->
Anti-Aging
Anti-Aging
Impact
Moderate effect
Typical dose:150–1000 mg
Resveratrol mimics some of the effects of caloric restriction, a known longevity intervention. While human data is still evolving, it shows consistent benefits for endothelial function and metabolic health, making it a key supplement for vascular aging.
View goal ->
Vision Support
Vision Support
Impact
Moderate effect
Typical dose:100–500 mg
Resveratrol helps combat oxidative stress and inhibits inflammatory pathways implicated in age-related macular degeneration (AMD) and diabetic retinopathy. It supports mitochondrial function in the high-energy environment of the retina, potentially preserving photoreceptor health.
View goal ->
Interactions

Positive Interactions

Vitamin C
Enhances overall antioxidant protection through synergistic effects.
Vitamin E
Synergistically boosts antioxidant defense and cellular protection.
Selenium
Contributes to enhanced antioxidant capacity and cellular health.
Coenzyme Q-10
Supports mitochondrial function and amplifies antioxidant effects.
Astaxanthin
Combines with other potent antioxidants for enhanced cellular protection.
Lycopene
Provides synergistic antioxidant benefits, particularly for cardiovascular health.
Green Tea
Both are rich in polyphenols, offering synergistic antioxidant and anti-inflammatory support.
Turmeric
Combines anti-inflammatory and antioxidant properties for enhanced effects.
Curcumin
Enhances anti-inflammatory and antioxidant pathways when combined with resveratrol.
Flavonoid
Flavonoids can enhance the bioavailability and efficacy of resveratrol.
Omega-3
Synergistic anti-inflammatory and cardiovascular benefits when taken together.
EPA (Eicosapentaenoic Acid)
Works with resveratrol to support cardiovascular health and reduce inflammation.
DHA
Supports brain and cardiovascular health with enhanced anti-inflammatory effects.
Fish Oil
Provides synergistic benefits for heart health and inflammation reduction.
carotenoids
Enhances overall antioxidant protection.

Negative Interactions

Vitamin K
Resveratrol may possess mild anti-clotting effects, potentially interfering with Vitamin K's role in blood coagulation, especially at high doses.
Iron
As a polyphenol, resveratrol may inhibit the absorption of non-heme iron when consumed concurrently.
Product stats
Price per product
Average$34.23
Median$27.97
Price per serving
Average$0.90
Median$0.69
Price distribution
Price per serving distribution
Price per
Paired ingredients