PalmettoGuard

PalmettoGuard

Life Extension4.4 (1,566 ratings)
Format:Softgel Quantity: 30 Softgel(s) · 30 servings
Goals

Product analysis

63 out of 100

PalmettoGuard combines saw palmetto and beta-sitosterol with a clearly identified boron source. The saw-palmetto preparation is unspecified, limiting comparison with more clearly characterized options.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality85

Bororganic glycine is a favorable identified boron form. Saw palmetto and rosemary preparations are unspecified, limiting a close comparison of the full mix.

Ingredient Transparency64

Most ingredient amounts are stated, but the cholesterol amount is missing. Several preparation details are also unspecified, leaving a less complete picture of the ingredients.

Value For Money32

The boron contribution is relatively costly. Value for saw palmetto, rosemary and the other contributions cannot be established reliably.

Customer Satisfaction77

Customer ratings are positive across a substantial number of entries. The larger pool gives a broader view of satisfaction without establishing lasting hormone effects.

Product Focus45

Boron provides a narrow link to mineral metabolism, with uncertain routine health and testosterone benefits. The wider formula includes ingredients whose specific contributions cannot be assessed confidently here.

Format
Softgel
Container
30 Softgel(s)
Per serving
$0.40
Customer rating
4.4 · 1,566 ratings
Report analysis

Goals

Hair Health
Impact
Situational effect
F Ingredient FitF PathwaysF EvidenceB Formulation Logic
Study evidence
Everyday Health
Impact
Moderate effect
D+ Ingredient FitF PathwaysB+ EvidenceA+ Formulation Logic
Boron · 3 mg

Boron at 3 mg is associated with mineral and bone metabolism in the saved findings. It is not established as an essential human nutrient, and small studies in specific settings do not demonstrate a routine broad health benefit.

How this product is rated for Everyday Health

Ingredient fit51

The assessed contribution sits within a broader formula with other actives that add no independent contribution in these findings. The assessed amount provides partial coverage of the saved dose comparison.
Goal fit
The assessed contribution sits within a broader formula with other actives that add no independent contribution in these findings.
Dose adequacy
The assessed amount provides partial coverage of the saved dose comparison.

Pathways19

The strongest saved contribution concerns bone and mineral metabolism, with limited coverage. No assessed health process reaches the saved coverage threshold.
Depth
The strongest saved contribution concerns bone and mineral metabolism, with limited coverage.
Breadth
No assessed health process reaches the saved coverage threshold.

Evidence82

Boron provides the strongest saved evidence contribution at the assessed amount; its scope and limitations still apply. The ingredients meeting the saved amount threshold have preparations accepted by the saved evidence assessment.
Evidence strength
Boron provides the strongest saved evidence contribution at the assessed amount; its scope and limitations still apply.
Studied preparation
The ingredients meeting the saved amount threshold have preparations accepted by the saved evidence assessment.

Formulation logic100

The assessed ingredients can contribute independently or have their required companion present. No ingredient conflict was identified by the saved checks. All ingredients included in the saved dose check reach its minimum threshold.
Partner coverage
The assessed ingredients can contribute independently or have their required companion present.
Conflicts
No ingredient conflict was identified by the saved checks.
Effective doses
All ingredients included in the saved dose check reach its minimum threshold.
Study evidence
Boron Supportive 6 studies
Impact
Moderate effect
D+ Ingredient FitF PathwaysC EvidenceA+ Formulation Logic
Boron · 3 mg

Boron has an uncertain effect on testosterone. Reports of hormone changes don't show that it reliably produces a lasting increase, and its presence here doesn't tell you whether you'll benefit. The declared amount cannot by itself resolve that uncertainty.

How this product is rated for Testosterone Support

Ingredient fit51

A lasting testosterone increase from boron remains uncertain.
Goal fit
Boron provides the main connection with testosterone, alongside ingredients with other roles.
Dose adequacy
Boron 3 mg per serving. These amounts do not predict a testosterone increase.

Pathways15

The ingredients have a possible connection with free testosterone, but this doesn't show that taking them reliably raises it.
Depth
The ingredients have a possible connection with free testosterone, but this doesn't show that taking them reliably raises it.
Breadth
No broad hormone pathway effect is identified from these ingredients and amounts.

Evidence63

A lasting testosterone increase from boron remains uncertain.
Evidence strength
A lasting testosterone increase from boron remains uncertain.
Studied preparation
The relevant ingredient preparations match the available context, but that match alone doesn't predict a testosterone benefit.

Formulation logic100

No specific ingredient conflict or missing required partner is identified.
Partner coverage
No required ingredient partner is missing; combining the ingredients doesn't imply an extra testosterone benefit.
Conflicts
No specific ingredient conflict is identified.
Effective doses
Boron supplies 3 mg per serving, without a reliable lasting testosterone benefit.
Study evidence
Boron Disputed 3 studies

Ingredients

IngredientAmount per servingScore
Calories
5 Calorie(s)
Total Fat
0.5 Gram(s)
Cholesterol
0 mg
Saw Palmetto CO2 extract
320 mg 25
Beta-Sitosterol (Pine)
90 mg
Boron (Albion Bororganic Glycine)
3 mg 86
Rosemary extract
400 mcg
Men 18–50
Report overview
A+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value
A serving supplies 3 mg boron as bororganic glycine. The whole-product serving costs about $0.40.
How this ingredient is rated

Active Ingredient Quality & Bioavailability100

Boron is supplied as bororganic glycine, a form rated favorably in the evaluation.
Boron Form & Bioavailability
Bororganic Glycine is rated favorably in the form evaluation.
Trademarked & High-Purity Sources
The evaluation records a recognized branded boron source.

Dose, Safety & Label Transparency100

The serving states 3 mg elemental boron and names its source form.
Elemental Dose Transparency
The saved label facts give 3 mg elemental boron per serving and identify the source form.
Dosage Efficacy & Safety Margin
A serving provides 3 mg boron, an amount the evaluation rates favorably.

Value30

The scaled whole-product cost is about $0.40 per 3 mg boron.
Price per 3mg Elemental Boron
The whole-product cost scales to about $0.40 per 3 mg boron; it includes all ingredients in the product.
F Composition And Label DisclosureF Composition And Label Disclosure
Each serving lists 320 mg of saw palmetto extract. The saved facts do not specify its fatty-acid percentage, limiting comparisons of composition.
How this ingredient is rated

Composition and Label Disclosure30

The preparation is identified as saw palmetto extract, but no fatty-acid percentage is recorded.
Marker and Preparation Disclosure
The preparation is identified as saw palmetto extract, but no fatty-acid percentage is recorded.

Composition and Label Disclosure20

The serving lists 320 mg of saw palmetto extract; no fatty-acid percentage is recorded.
Amount and Label Disclosure
The serving amount is recorded as 320 mg, while the fatty-acid percentage is unavailable.

Commercial Price and Usability

No commercial price comparison was evaluated.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Effects of boron supplementation on the severity and duration of pain in primary dysmenorrhea.
    Nikkhah S; Dolatian M; Naghii MR; Zaeri F; Taheri SM · Complementary therapies in clinical practice · 2015
    Randomized trial113 participantsEveryday Health forBoron
  2. Efficacy and safety of tavaborole topical solution, 5%, a novel boron-based antifungal agent, for the treatment of toenail onychomycosis: Results from 2 randomized phase-III studies.
    Elewski BE; Aly R; Baldwin SL; González Soto RF; Rich P; Weisfeld M; Wiltz H; Zane LT; Pollak R · Journal of the American Academy of Dermatology · 2015
    Randomized trialEveryday Health forBoron
  3. The efficacy and safety of tavaborole, a novel, boron-based pharmaceutical agent: phase 2 studies conducted for the topical treatment of toenail onychomycosis.
    Toledo-Bahena ME; Bucko A; Ocampo-Candiani J; Herz-Ruelas ME; Jones TM; Jarratt MT; Pollak RA; Zane LT · Journal of drugs in dermatology : JDD · 2015
    Clinical trial336 participantsEveryday Health forBoron
  4. Boron neutron capture therapy (BNCT) for glioblastoma multiforme: a phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA).
    Henriksson R; Capala J; Michanek A; Lindahl SA; Salford LG; Franzén L; Blomquist E; Westlin JE; Bergenheim AT; Swedish Brain Tumour Study Group · Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2009
    Single-arm trial30 participantsEveryday Health forBoron
  5. Effects of Calcium Fructoborate on Levels of C-Reactive Protein, Total Cholesterol, Low-Density Lipoprotein, Triglycerides, IL-1β, IL-6, and MCP-1: a Double-blind, Placebo-controlled Clinical Study
    Otilia-Constantina Rogoveanu, George Dan Mogosanu, Cornelia Bejenaru, Ludovic Everard Bejenaru, Octavian Croitoru, Johny Neamtu, Zbigniew Pietrzkowski, Tania Reyes-Izquierdo, Andrei Bita, Iulia Daria Scorei, Romulus Ion Scorei · Biological Trace Element Research · 2015
    Randomized trial78 participantsEveryday Health forBoron
  6. The Safety and Efficacy of a Proprietary Bioactive Fatty Acids Extract From Saw Palmetto (Serenoa repens) for Promoting Hair Growth and Reducing Hair Loss in Adults With Self-Perceived Thinning Hair: 90-Day Results.
    Ablon G · Journal of cosmetic dermatology · 2025
    Randomized trial60 participantsHair Health forSaw Palmetto
  7. Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
    Zhou L; Zhu W; Chen Y · Frontiers in nutrition · 2026
    Meta-analysis1,658 participants19 studies pooledHair Health forSaw Palmetto
  8. The Safety and Efficacy of a Novel Saw Palmetto (Serenoa repens) Extract for Promoting Hair Growth in Adults With Self-Perceived Thinning Hair: 180-Day Results.
    Ablon G · Journal of cosmetic dermatology · 2026
    Randomized trial60 participantsHair Health forSaw Palmetto
  9. Beyond Minoxidil: Off-Label Therapies for Male Androgenetic Alopecia-A Systematic Review with Network Meta-Analyses.
    Gupta AK; Compton SAH; Liddy A; Talukder M; Wang T; Bamimore MA · Medicina (Kaunas, Lithuania) · 2026
    Meta-analysis50 participants23 studies pooledHair Health forSaw Palmetto
  10. Comparitive effectiveness of finasteride vs Serenoa repens in male androgenetic alopecia: a two-year study.
    Rossi A; Mari E; Scarno M; Garelli V; Maxia C; Scali E; Iorio A; Carlesimo M · International journal of immunopathology and pharmacology · 2013
    Non-randomized trial100 participantsHair Health forSaw Palmetto
  11. Biochemical and physiologic consequences of boron deprivation in humans.
    Nielsen FH · Environmental health perspectives · 1995
    Single-arm trial12 participantsTestosterone Support forBoron
  12. Plasma boron and the effects of boron supplementation in males.
    Green NR; Ferrando AA · Environmental health perspectives · 1995
    Randomized trial19 participantsTestosterone Support forBoron
  13. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
    Mohammad Reza Naghii, Mahmoud Mofid, Ali Reza Asgari, Mehdi Hedayati, Maryam-Saddat Daneshpour · Journal of Trace Elements in Medicine and Biology · 2011
    Non-randomized trial8 participantsTestosterone Support forBoron