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Saw Palmetto

notesDescription

Saw Palmetto is a small palm tree native to the southeastern United States, with its therapeutic properties primarily found in its dark berries. The extract from these berries is rich in fatty acids, phytosterols, and flavonoids, which are believed to be responsible for its health benefits. It is commonly used as a natural supplement for various health concerns. The primary mechanism of action for Saw Palmetto is thought to involve the inhibition of 5-alpha-reductase, an enzyme responsible for converting testosterone into dihydrotestosterone (DHT). DHT is a potent androgen that plays a crucial role in prostate growth and hair loss. By inhibiting this enzyme, Saw Palmetto may help reduce the size of the prostate and alleviate associated urinary symptoms. Beyond its hormonal effects, Saw Palmetto also exhibits anti-inflammatory properties, which can be beneficial in reducing inflammation associated with prostate conditions. It may also contribute to improved urinary flow and overall urinary tract comfort. While most research focuses on men's health, its anti-inflammatory and hormonal balancing effects may have broader applications.

ecoSources
Berries of the Saw Palmetto palm tree (Serenoa repens)
Cheapest Saw Palmetto Supplements
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scheduleTiming & Intake
scheduleAnytimerestaurantWith food
infoTaking Saw Palmetto with food can help minimize potential mild stomach upset.
check_circleOptimal Dosage
Minimum160 mg
Maximum320 mg
report_problemSafety & Toxicity
track_changesGoals
Hair Health
content_cutHair Health
Impact
Situational effect
Typical dose:160–320 mg
Saw Palmetto is thought to inhibit the enzyme 5-alpha-reductase, which converts testosterone to dihydrotestosterone (DHT). DHT is the primary hormone responsible for shrinking hair follicles and causing male and female pattern baldness. This makes it an excellent choice for this specific type of hair loss.
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sync_altInteractions

add_circle_outlinePositive Interactions

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Stinging Nettle
Often combined with Saw Palmetto in supplements for benign prostatic hyperplasia (BPH) as they are believed to work synergistically to support prostate health.
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Zinc
An essential mineral for prostate health; its supplementation can complement Saw Palmetto's actions in supporting overall prostate function.
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Selenium
An antioxidant known to play a role in prostate health, potentially offering broader cellular protection when combined with Saw Palmetto.
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Lycopene
A powerful antioxidant particularly beneficial for prostate health, which can synergistically support the prostate alongside Saw Palmetto's hormonal and anti-inflammatory effects.
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Turmeric
Its active compound Curcumin (41497) has strong anti-inflammatory properties, which can complement Saw Palmetto by helping to reduce prostate inflammation.

remove_circle_outlineNegative Interactions

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Omega-3
Saw Palmetto may possess mild antiplatelet effects, which could theoretically add to the mild blood-thinning properties of Omega-3 fatty acids, potentially increasing the risk of bleeding or bruising.
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Fish Oil
Saw Palmetto may possess mild antiplatelet effects, which could theoretically add to the mild blood-thinning properties of Fish Oil, potentially increasing the risk of bleeding or bruising.
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EPA (Eicosapentaenoic Acid)
Saw Palmetto may possess mild antiplatelet effects, which could theoretically add to the mild blood-thinning properties of EPA, potentially increasing the risk of bleeding or bruising.
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DHA
Saw Palmetto may possess mild antiplatelet effects, which could theoretically add to the mild blood-thinning properties of DHA, potentially increasing the risk of bleeding or bruising.
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82 Best Prostate Wellness

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Bio Nutrition
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Saw Palmetto: 500 mg
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60 Value Saw Palmetto for Him 450 mg

Saw Palmetto for Him 450 mg

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90 Best SP Ultimate

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Saw Palmetto: 640 mg
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82 Budget Saw Palmetto 160 mg

Saw Palmetto 160 mg

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Saw Palmetto: 160 mg
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72 Value Saw Palmetto 450 mg

Saw Palmetto 450 mg

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Saw Palmetto: 450 mg
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Source Naturals
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Saw Palmetto: 712 mg
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80 Best Saw Palmetto

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Saw Palmetto: 598 mg
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70 Value Saw Palmetto 450 mg

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Nature's Bounty
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Saw Palmetto: 450 mg
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68 Value Saw Palmetto Berries 585 mg

Saw Palmetto Berries 585 mg

Nature's Way
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Saw Palmetto: 585 mg
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65 Value Saw Palmetto Berries 585 mg

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Saw Palmetto: 585 mg
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Buy for $10.89(from iHerb)
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85 Best Saw Palmetto Pygeum Nettle Root

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68 Value Saw Palmetto 540 mg

Saw Palmetto 540 mg

Swanson
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Saw Palmetto: 540 mg
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77 Budget Saw Palmetto Extract 160 mg

Saw Palmetto Extract 160 mg

NOW
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Saw Palmetto: 160 mg
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86 Best Men's Life Force Multiple

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Saw Palmetto: 640 mg
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68 Value Saw Palmetto 580 mg

Saw Palmetto 580 mg

Solaray
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Saw Palmetto: 580 mg
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69 Value Saw Palmetto 580 mg

Saw Palmetto 580 mg

Solaray
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Saw Palmetto: 580 mg
An extremely economical Solaray product providing 580 mg of whole Saw Palmetto in VegCaps, recognized for its large quantity and high customer satisfaction.
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70 Value Saw Palmetto 450 mg

Saw Palmetto 450 mg

21st Century
4.6
★★★★★
(5727 ratings)
Saw Palmetto: 450 mg
A budget-friendly capsule offering 450mg of saw palmetto powder and 15mg of well-absorbed zinc picolinate for foundational support.
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analyticsProduct stats
sellPrice per product
Average$34.18
Median$25.00
restaurantPrice per serving
Average$0.75
Median$0.66
sciencePrice per 100 mg
Average$0.27
Median$0.21
bar_chartPrice distribution
bar_chartPrice per serving distribution
bar_chartPrice per 100 mg
Reference amount: 100 mg
categoryForms
bar_chartPaired ingredients
water_dropIngredient forms
category Fatty Acids (29) 80
Saw Palmetto berries are rich in various fatty acids, which are considered the main biologically active constituents. These include saturated fatty acids like lauric acid and myristic acid, and unsaturated fatty acids such as oleic acid and palmitic acid. These compounds are believed to be crucial for Saw Palmetto's mechanism of action, primarily by inhibiting the enzyme 5-alpha-reductase.
thumb_upPros
  • Directly involved in the primary mechanism of action (5-alpha-reductase inhibition)
  • Often standardized in high-quality Saw Palmetto extracts
  • Well-researched for their role in Saw Palmetto's effects
thumb_downCons
  • Typically consumed as part of a complex extract rather than isolated
  • Efficacy depends on the specific profile and concentration of different fatty acids
sellPer product
Avg$33.49
Med$25.00
restaurantPer serving
Avg$0.77
Med$0.70
science Per 100 mg
Avg$0.27
Med$0.22
Price distribution
category total Fatty Acids (5) 85
Many Saw Palmetto extracts are standardized to contain a high percentage of 'Total Fatty Acids', typically 85-95%. This standardization ensures a concentrated source of the active compounds believed to inhibit 5-alpha-reductase. These fatty acids are crucial for Saw Palmetto's ability to interfere with the conversion of testosterone to DHT, a primary mechanism for its potential benefits in hair health.
thumb_upPros
  • Common and reliable standardization for potent Saw Palmetto extracts
  • Directly linked to the main mechanism of action (5-alpha-reductase inhibition)
  • Ensures a high concentration of the key active compounds
thumb_downCons
  • The specific profile of fatty acids can vary between extracts, affecting nuanced efficacy
  • May not fully account for the synergistic effects of other minor compounds like sterols
sellPer product
Avg$36.08
Med$26.33
restaurantPer serving
Avg$0.92
Med$0.87
science Per 100 mg
Avg$0.27
Med$0.24
Price distribution
category Total Fatty Acids (5) 85
Many Saw Palmetto extracts are standardized to contain a high percentage of 'Total Fatty Acids', typically 85-95%. This standardization ensures a concentrated source of the active compounds believed to inhibit 5-alpha-reductase. These fatty acids are crucial for Saw Palmetto's ability to interfere with the conversion of testosterone to DHT, a primary mechanism for its potential benefits in hair health.
thumb_upPros
  • Common and reliable standardization for potent Saw Palmetto extracts
  • Directly linked to the main mechanism of action (5-alpha-reductase inhibition)
  • Ensures a high concentration of the key active compounds
thumb_downCons
  • The specific profile of fatty acids can vary between extracts, affecting nuanced efficacy
  • May not fully account for the synergistic effects of other minor compounds like sterols
sellPer product
Avg$36.08
Med$26.33
restaurantPer serving
Avg$0.92
Med$0.87
science Per 100 mg
Avg$0.27
Med$0.24
Price distribution
category Active Sterols (3) 80
The term 'Active Sterols' emphasizes the functional components among the plant sterols found in Saw Palmetto. These sterols, with beta-sitosterol being the most prominent, are directly involved in the mechanism of action that benefits hair health: inhibiting the enzyme 5-alpha-reductase. By reducing the conversion of testosterone to DHT, these active sterols help to mitigate hair loss associated with androgenetic alopecia.
thumb_upPros
  • Focuses on the most functionally significant sterol components
  • Implies a higher quality extract that emphasizes known active ingredients
  • Directly targets the mechanism of DHT reduction
thumb_downCons
  • Can sometimes be a marketing term if not accompanied by specific standardization percentages
  • May not capture the full synergistic effect of all fatty acids present in the berry oil
sellPer product
Avg$32.64
Med$33.56
restaurantPer serving
Avg$0.66
Med$0.70
science Per 100 mg
Avg$0.11
Med$0.11
Price distribution
category Beta-Sitosterol (2) 85
Beta-Sitosterol is one of the most studied phytosterols in Saw Palmetto, known for its ability to help inhibit the enzyme 5-alpha-reductase. This enzyme is responsible for converting testosterone into dihydrotestosterone (DHT), a hormone strongly linked to androgenetic alopecia (pattern baldness) and prostate enlargement. While not the sole active compound, beta-sitosterol plays a key role in the plant's overall therapeutic effects.
thumb_upPros
  • Specific compound with established anti-androgenic activity
  • Contributes to 5-alpha-reductase inhibition
  • Can be standardized in extracts for consistent potency
thumb_downCons
  • May not capture the full synergistic effects of all Saw Palmetto compounds if used in isolation
  • Often more expensive to isolate and standardize compared to total extracts
sellPer product
Avg$22.02
Med$22.02
restaurantPer serving
Avg$0.26
Med$0.26
science Per 100 mg
Avg$0.06
Med$0.06
Price distribution
category fatty acids and sterols (2) 80
Saw Palmetto berries are rich in various fatty acids, which are considered the main biologically active constituents. These include saturated fatty acids like lauric acid and myristic acid, and unsaturated fatty acids such as oleic acid and palmitic acid. These compounds are believed to be crucial for Saw Palmetto's mechanism of action, primarily by inhibiting the enzyme 5-alpha-reductase.
thumb_upPros
  • Directly involved in the primary mechanism of action (5-alpha-reductase inhibition)
  • Often standardized in high-quality Saw Palmetto extracts
  • Well-researched for their role in Saw Palmetto's effects
thumb_downCons
  • Typically consumed as part of a complex extract rather than isolated
  • Efficacy depends on the specific profile and concentration of different fatty acids
sellPer product
Avg$62.28
Med$62.28
restaurantPer serving
Avg$1.03
Med$1.03
science Per 100 mg
Avg$0.32
Med$0.32
Price distribution
category free Fatty Acids (2) 80
Free fatty acids are those not bound to other molecules (like glycerol) and are thus in a more direct form for biological activity. In Saw Palmetto, these free fatty acids are believed to be the specific components that directly interact with and inhibit the 5-alpha-reductase enzyme. This inhibition reduces the conversion of testosterone to DHT, which is crucial for addressing hair loss related to androgenetic alopecia.
thumb_upPros
  • Represents the directly bioavailable and active form of fatty acids
  • More readily available for interaction with target enzymes
thumb_downCons
  • Difficult to precisely isolate or standardize specifically for 'free fatty acids' in commercial extracts, which often specify 'Total Fatty Acids'
  • Stability might be a concern compared to esterified forms in some contexts
sellPer product
Avg$40.68
Med$40.68
restaurantPer serving
Avg$1.35
Med$1.35
science Per 100 mg
Avg$0.58
Med$0.58
Price distribution
category Sterols (2) 70
Sterols, also known as phytosterols, are a class of plant-derived compounds present in Saw Palmetto. These include beta-sitosterol, campesterol, and stigmasterol, among others. They are recognized for their role in contributing to the extract's medicinal properties, especially in inhibiting the enzyme 5-alpha-reductase, which is involved in the conversion of testosterone to DHT. This action is relevant for addressing hair loss caused by excess DHT.
thumb_upPros
  • Essential active components of Saw Palmetto
  • Contribute to the plant's efficacy against DHT-related issues
thumb_downCons
  • A general term; specific impact depends on the concentration and type of sterols present
  • Less precise for standardization compared to 'Total Sterols' or 'Beta-Sitosterol'
sellPer product
Avg$19.50
Med$19.50
restaurantPer serving
Avg$0.81
Med$0.81
science Per 100 mg
Avg$0.29
Med$0.29
Price distribution
category Total Sterols (2) 75
Total sterols refer to the sum of various plant sterols naturally occurring in Saw Palmetto berries. These sterols, particularly beta-sitosterol, campesterol, and stigmasterol, are considered important active components alongside fatty acids. They work synergistically to exert effects such as inhibiting 5-alpha-reductase, which is critical for managing conditions like androgenetic alopecia by reducing DHT production.
thumb_upPros
  • Represents a significant active fraction of the Saw Palmetto plant
  • Includes multiple compounds that contribute to the desired effects
  • Often part of standardization for comprehensive extracts
thumb_downCons
  • Less specific than standardizing for individual active sterols like beta-sitosterol
  • The overall effectiveness can depend on the specific profile of sterols included
sellPer product
Avg$22.02
Med$22.02
restaurantPer serving
Avg$0.26
Med$0.26
science Per 100 mg
Avg$0.06
Med$0.06
Price distribution

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