Testosterone Support title image

Testosterone Support

Fitness & Performance

Testosterone support focuses on normal hormonal wellbeing and the everyday functions associated with it, including physical vitality, muscle function, and male reproductive health. These areas are connected to nutrition, activity, and recovery, as well as individual circumstances. A useful approach starts with the outcome that matters to you and places it within that wider context. Nutritional support has several possible roles. Essential nutrients contribute to normal physiological processes, while targeted ingredients are used for particular aspects of vitality or recovery. The purpose of a formulation should be clear, especially when several ingredients act on related pathways or overlap with products already in your routine. Energy, training capacity, sleep, and general wellbeing can help give your priorities practical meaning. Where hormone measurements are relevant, they provide additional information within an appropriate assessment. Looking at the whole picture helps keep support focused on your needs and the functions you want to maintain.

Warnings

  • Assess hormone-related symptoms: Discuss persistent fatigue, reduced libido, or changes in physical function with a clinician. Appropriate assessment and testing help distinguish hormonal needs from other possible causes.
  • Coordinate hormone and fertility concerns: Seek advice if fertility or a hormone-sensitive condition is part of the concern. Testosterone-marketed products are not established fertility treatments, and hormone-related treatment decisions need appropriate clinical oversight.
  • Check medicine interactions: Ask a pharmacist or clinician to review your exact products alongside your medicines. The ingredient, amount, and treatment determine which combinations are suitable.
  • Avoid overlapping high doses: Count nutrients from multivitamins, individual supplements, and fortified products together. Keep the combined amounts within appropriate limits for your circumstances.
Ingredient overview

Goal guidance

Lifestyle changes

Balance resistance training and regular activity with enough sleep and recovery. Avoid repeatedly pushing through exhaustion, and keep changes in strength, energy, and wellbeing in context.

Diet changes

Eat enough for your activity and include varied protein foods, dietary fats, and micronutrient sources. Review nutritional gaps before adding a concentrated mineral or hormone-focused blend.

Who this is for

Adults interested in normal hormonal function, physical vitality, and nutritional support for an active, well-recovered routine.

Who should be careful

Seek individual advice for fertility concerns, hormone-sensitive conditions, or relevant medicines. Choose products with reliable quality controls, and coordinate hormone testing or treatment with a qualified clinician.

Expected timeline

Follow energy, training, sleep, and recovery together over time. Where hormone levels need assessment, use appropriate testing and a review plan instead of relying on a single sensation.

Common mistakes

Adding hormone-focused products while training heavily and sleeping poorly can miss the foundations. Check overlapping nutrients and give recovery a clear place in the plan.

Ingredients

Magnesium Minerals
Impact
Highest effect
Typical dose200–420 mg / day

While essential for hundreds of enzymatic reactions, magnesium's key role here is its ability to inhibit SHBG from binding to testosterone. This action increases the amount of 'free' testosterone circulating in the body, which is the form that is biologically active and can exert its effects on tissues.

Focuses on
Free testosterone bioactivityTotal testosterone levelsHormonal balance in agingExercise-induced supportMagnesium status
Most relevant for
Aging men or athletes looking to maintain optimal magnesium levels to support testosterone bioactivity.

Potential benefits

  • Hormonal Support for Athletes.Research in athletes suggests that four weeks of supplementation may increase both free and total testosterone levels, with more pronounced results observed during regular exercise.
  • Correlation in Aging Men.Unconfirmed. Observational studies in older men show that higher blood magnesium levels are strongly linked to higher total testosterone and anabolic hormone status.
  • Support for Bioavailable Testosterone.Unconfirmed. Magnesium may inhibit sex hormone-binding globulin (SHBG) from binding to testosterone, which is theorized to increase the amount of biologically active free testosterone.

Limitations

  • No Effect in PCOS.Clinical trials and meta-analyses in women with polycystic ovary syndrome have shown no significant impact on testosterone levels or other hormonal markers from magnesium supplementation.
  • Inconsistent Evidence.While some small studies show increases, consistent testosterone-boosting effects from supplementation have not been established across all healthy or clinical populations.
  • Observational Constraints.Evidence in older men is primarily correlational; these associations do not prove that magnesium supplementation will directly increase testosterone levels in individuals with normal status.

Study evidence

5 studies

Magnesium status has been linked with testosterone-related measures, but supplementation has not been shown to produce a consistent testosterone-boosting effect. The research addresses different populations and hormonal goals, limiting its relevance to general testosterone support.

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Vitamin D Vitamins
Impact
Highest effect
Typical dose1000–4000 IU / day

Vitamin D receptors are present in the testes, and as a secosteroid hormone, it plays a direct role in the synthesis of testosterone. Numerous studies have shown a significant positive association between blood Vitamin D levels and total testosterone, making the correction of any deficiency a foundational step.

Focuses on
Deficiency correctionBiological foundationBioavailable fractionHormone synthesis
Most relevant for
Men who are vitamin D deficient and seeking to address foundational factors for hormone health.

Potential benefits

  • Hormonal Synthesis Foundation.Unconfirmed. Vitamin D receptors are present in the testes, suggesting a biological role in the production process, although clinical trials have not consistently proven that supplementation raises testosterone levels.
  • Bioavailable Testosterone Support.Unconfirmed. Limited evidence suggests that maintaining vitamin D levels might help preserve the free or bioavailable portion of testosterone during periods of intensive physical training.
  • Deficiency-Related Correlation.Unconfirmed. Large observational studies link higher vitamin D status with better testosterone profiles, but this relationship is often not replicated in interventional studies.

Limitations

  • Inconsistent Boosting Effect.Systematic reviews and multiple randomized trials conclude that vitamin D supplementation does not significantly increase total testosterone in most men.
  • Population Constraints.In women with polycystic ovary syndrome, vitamin D often acts to reduce abnormally high androgens rather than supporting or increasing them.
  • Observational vs Causal Evidence.While blood levels are often correlated, high-quality trials frequently report no effect on hormone levels even after vitamin D status is successfully improved.
Things to consider

Extremely high blood levels of vitamin D, exceeding 102 nmol/L, have been paradoxically associated with a higher risk of low testosterone in some observational research.

Study evidence

56 studies

Vitamin D supplementation has not reliably increased testosterone in men, including in some studies of vitamin D deficiency. Although vitamin D and testosterone levels are sometimes linked, the available research does not establish vitamin D as a dependable testosterone booster.

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Zinc Minerals
Impact
Highest effect
Typical dose15–40 mg / day

Zinc is a critical cofactor for enzymes involved in testosterone production. It also plays a role in inhibiting aromatase, the enzyme that converts testosterone to estrogen. Deficiency, which can be common in athletes, is directly linked to hypogonadism and low testosterone.

Focuses on
Testosterone synthesisHormone balanceNutritional status restorationTesticular health
Most relevant for
Men with marginal zinc deficiency or those looking to support natural hormone production through essential mineral intake.

Potential benefits

  • Restores Levels in Deficiency.Correcting a zinc deficiency has been shown to significantly increase serum testosterone concentrations in men with low baseline levels.
  • Supports Testicular Health.Zinc is an essential trace element required for normal testicular function and the biological processes involved in male fertility.
  • Prevents Nutrient-Related Decline.Maintaining adequate zinc intake helps prevent the significant drop in testosterone levels associated with dietary zinc restriction.

Limitations

  • Baseline Status Dependent.The hormonal benefits of zinc are primarily observed in individuals who are already deficient; it may not raise testosterone in well-nourished men.
  • Uncertain Clinical Impact.Modest increases in blood testosterone levels from zinc may not translate into tangible benefits for muscle mass or physical performance.
  • Limited Evidence for Healthy Men.There is a lack of evidence establishing that supplemental zinc provides a dependable testosterone boost for men with already adequate zinc status.
Things to consider

The degree of response to zinc depends on your starting zinc and testosterone levels, the dosage used, and the duration of supplementation.

Study evidence

7 studies

Zinc deficiency can reduce testosterone, and restoring zinc status may improve levels in deficient men. The available research does not establish that extra zinc reliably raises testosterone in men who already have adequate zinc status, or that hormonal changes necessarily improve symptoms or performance.

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Ashwagandha Botanicals
Impact
High effect
Typical dose300–600 mg / day

Ashwagandha's primary mechanism is the significant reduction of cortisol levels. Chronically elevated cortisol can suppress the hypothalamic-pituitary-gonadal (HPG) axis, leading to lower testosterone. By mitigating this stress response, Ashwagandha creates a more favorable anabolic environment, with multiple clinical trials showing direct increases in testosterone levels.

Focuses on
Serum testosterone levelsCortisol managementMale sexual well-beingMuscle strength supportStress adaptation
Most relevant for
Healthy men looking to optimize hormonal health and physical resilience, especially when managing stress-induced fatigue.

Potential benefits

  • Enhanced Testosterone Levels.Meta-analyses of multiple trials indicate that ashwagandha root extracts can lead to a significant increase in serum testosterone levels in men.
  • Reduced Stress Impact.By lowering cortisol levels, ashwagandha may help prevent the stress-induced suppression of the hypothalamic-pituitary-gonadal axis.
  • Physical Performance Gains.Research shows that the hormonal support provided by ashwagandha can translate to improved muscle strength, especially in physically active men.

Limitations

  • Limited Efficacy in Women.Multiple studies focused on perimenopausal or healthy women found no significant change in testosterone levels following supplementation.
  • Variability in Effect Size.Some randomized controlled trials observed that while testosterone increased, the change was not always significantly greater than the placebo group.
  • Clinical Significance Uncertainty.While serum levels may rise, it is unclear if these increases lead to meaningful clinical improvements for men with medical hormone deficiencies.

Study evidence

17 studies

Ashwagandha can modestly increase testosterone in men, although results vary across extracts and populations. Evidence in women does not show the same effect, and higher hormone measurements do not establish that it treats testosterone deficiency or consistently improves related symptoms.

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Boron Minerals
Impact
High effect
Typical dose3–10 mg / day

The evidence for Boron's ability to significantly decrease Sex Hormone-Binding Globulin (SHBG) and thereby increase free testosterone is quite robust, especially in the short term. This places its efficacy above other situational botanicals.

Focuses on
Free testosterone levelsSHBG modulationHormonal repletionEstradiol balance
Most relevant for
Individuals looking to optimize free testosterone levels or those correcting a low dietary intake of boron.

Potential benefits

  • Free Testosterone Modulation.Unconfirmed. Boron may increase free testosterone by lowering sex hormone-binding globulin (SHBG), but this benefit is unproven as a controlled trial in bodybuilders showed no effect.
  • Nutritional Repletion.Supplements can help restore testosterone levels in individuals who are correcting a specific dietary boron deficiency.
  • Hormonal Environment Support.Unconfirmed. Preliminary data suggest boron may reduce estradiol levels, though this effect on the androgen-estrogen ratio is unproven due to a lack of large-scale trials.

Limitations

  • Inconsistent Clinical Results.A 7-week randomized controlled trial in male bodybuilders found no significant increase in testosterone, muscle mass, or strength.
  • Small Study Populations.Most supportive evidence for hormonal changes comes from very small study groups, which may not represent the general population.
  • Short-Term Data.Findings regarding increased free testosterone are primarily based on short-term or acute studies, leaving long-term efficacy unclear.

Study evidence

3 studies

Boron has inconsistent evidence for increasing testosterone. Hormonal changes in uncontrolled research and during recovery from a low-boron diet contrast with a placebo-controlled study showing no testosterone benefit, so the available evidence does not establish reliable testosterone support in adequately nourished men.

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Creatine Other Nutrients
Impact
High effect
Typical dose3–5 g / day

Creatine's ability to increase DHT, a powerful testosterone metabolite, is well-documented. This hormonal shift, combined with its primary effect of improving strength and work capacity, creates a highly anabolic environment.

Focuses on
Hormonal ResponseAthletic TrainingAnabolic Environment
Most relevant for
Athletes and resistance trainers interested in how performance supplements might interact with training-related hormones.

Potential benefits

  • Support for Training-Induced Hormones.Unconfirmed. Some research in high-intensity athletes suggests creatine may help maintain a favorable testosterone-to-cortisol ratio during heavy training, though results are inconsistent across different sports.
  • Resting Testosterone Support.Unconfirmed. Small trials in strength athletes have observed increases in resting testosterone levels, but these effects are often not replicated in larger, controlled studies.

Limitations

  • Inconsistent Evidence.Systematic reviews and several randomized trials find no significant increase in total or free testosterone levels in healthy, resistance-trained men.
  • Limited Clinical Applicability.Current data does not support using creatine to treat clinically low testosterone or other medical hormonal deficiencies.
  • Variable DHT Response.Evidence regarding changes to dihydrotestosterone (DHT) is mixed, with recent long-term studies showing no significant hormonal or hair-related changes.
Things to consider

Users should not expect significant hormonal changes, as large-scale reviews find it ineffective for raising total testosterone in most populations.

Study evidence

5 studies

Creatine is not a reliable testosterone booster based on the available research. Although some athletic studies report increases, other controlled trials find no hormonal advantage, and benefits from combinations with other supplements cannot be attributed to creatine alone.

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Studies

Explore published research for this goal.

Sources

Up to five highest-ranked published examples per ingredient. Study counts and charts include all published studies for the connection.

  1. Magnesium and anabolic hormones in older men.
    Maggio M; Ceda GP; Lauretani F; Cattabiani C; Avantaggiato E; Morganti S; Ablondi F; Bandinelli S; Dominguez LJ; Barbagallo M; Paolisso G; Semba RD; Ferrucci L · International journal of andrology · 2012
    Cohort study399 participantsMagnesium
  2. Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging.
    Rotter I; Kosik-Bogacka DI; Dołęgowska B; Safranow K; Kuczyńska M; Laszczyńska M · Environmental geochemistry and health · 2017
    Cross-sectional study313 participantsMagnesium
  3. Effect of magnesium supplementation in improving hyperandrogenism, hirsutism, and sleep quality in women with polycystic ovary syndrome: A randomized, placebo-controlled clinical trial.
    Gholizadeh-Moghaddam M; Ghasemi-Tehrani H; Askari G; Jaripur M; Clark CCT; Rouhani MH · Health science reports · 2024
    Randomized trial64 participantsMagnesium
  4. The effects of trace element supplementation on glycolipid metabolism in PCOS: a systematic review and meta-analysis.
    Yang L; Gao Y; Zhao W; Qi Y; Duo X; Wang H · Frontiers in nutrition · 2025
    Meta-analysis1,600 participants25 studies pooledMagnesium
  5. Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion.
    Cinar V; Polat Y; Baltaci AK; Mogulkoc R · Biological trace element research · 2011
    Non-randomized trial20 participantsMagnesium
  6. Effect of Two Different Doses of Vitamin D Supplementation on Metabolic Profiles of Insulin-Resistant Patients with Polycystic Ovary Syndrome.
    Jamilian M; Foroozanfard F; Rahmani E; Talebi M; Bahmani F; Asemi Z · Nutrients · 2018
    Randomized trial90 participantsVitamin D
  7. Androgens and hirsutism score of overweight women with polycystic ovary syndrome improved after vitamin D treatment: A randomized placebo controlled clinical trial.
    Al-Bayyari N; Al-Domi H; Zayed F; Hailat R; Eaton A · Clinical nutrition (Edinburgh, Scotland) · 2021
    Randomized trial60 participantsVitamin D
  8. Association between plasma 25-OH vitamin D and testosterone levels in men.
    Nimptsch K; Platz EA; Willett WC; Giovannucci E · Clinical endocrinology · 2012
    Case-control study1,362 participantsVitamin D
  9. Causal Link Between Vitamin D and Total Testosterone in Men: A Mendelian Randomization Analysis.
    Chen C; Zhai H; Cheng J; Weng P; Chen Y; Li Q; Wang C; Xia F; Wang N; Lu Y · The Journal of clinical endocrinology and metabolism · 2020
    Other4,254 participantsVitamin D
  10. Associations of vitamin D status and vitamin D-related polymorphisms with sex hormones in older men.
    Rafiq R; van Schoor NM; Sohl E; Zillikens MC; Oosterwerff MM; Schaap L; Lips P; de Jongh RT · The Journal of steroid biochemistry and molecular biology · 2017
    Cohort study643 participantsVitamin D
  11. Environmental exposure to metals and male reproductive hormones: circulating testosterone is inversely associated with blood molybdenum.
    Meeker JD; Rossano MG; Protas B; Padmanahban V; Diamond MP; Puscheck E; Daly D; Paneth N; Wirth JJ · Fertility and sterility · 2010
    Cross-sectional study219 participantsZinc
  12. Nonpharmacological Interventions for the Management of Testosterone and Sperm Parameters: A Scoping Review.
    Santos HO; Cadegiani FA; Forbes SC · Clinical therapeutics · 2022
    Scoping reviewZinc
  13. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.
    Fallah A; Mohammad-Hasani A; Colagar AH · Journal of reproduction & infertility · 2020
    Narrative reviewZinc
  14. Clinical, endocrinological and biochemical effects of zinc deficiency.
    Prasad AS · Clinics in endocrinology and metabolism · 1986
    Narrative reviewZinc
  15. Clinical, endocrinologic, and biochemical effects of zinc deficiency.
    Prasad AS · Special topics in endocrinology and metabolism · 1986
    Narrative reviewZinc
  16. Effects of Withania somnifera (L.) Dunal (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis.
    Zhu X; Zeng Q; Lei Y; Xu D · Frontiers in pharmacology · 2026
    Meta-analysis1,249 participants20 studies pooledAshwagandha
  17. Effect of standardized root extract of ashwagandha (Withania somnifera) on well-being and sexual performance in adult males: A randomized controlled trial.
    Chauhan S; Srivastava MK; Pathak AK · Health science reports · 2024
    Randomized trial50 participantsAshwagandha
  18. Examining the Effects of Herbs on Testosterone Concentrations in Men: A Systematic Review.
    Smith SJ; Lopresti AL; Teo SYM; Fairchild TJ · Advances in nutrition (Bethesda, Md.) · 2021
    Systematic review32 studies pooledAshwagandhaFenugreek
  19. Do "testosterone boosters" really increase serum total testosterone? A systematic review.
    Morgado A; Tsampoukas G; Sokolakis I; Schoentgen N; Urkmez A; Sarikaya S · International journal of impotence research · 2024
    Systematic review3 studies pooledAshwagandhaCreatine
  20. Safety and Tolerability of Withania somnifera Root Extract in Healthy Male Participants: A Pilot Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
    Vaidya N; Agarwal R; Kshirsagar P; Ganu G; Nagore D; Mehta A; Vora A; Nair S · Food science & nutrition · 2025
    Randomized trial40 participantsAshwagandha
  21. Biochemical and physiologic consequences of boron deprivation in humans.
    Nielsen FH · Environmental health perspectives · 1995
    Single-arm trial12 participantsBoron
  22. Plasma boron and the effects of boron supplementation in males.
    Green NR; Ferrando AA · Environmental health perspectives · 1995
    Randomized trial19 participantsBoron
  23. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
    Mohammad Reza Naghii, Mahmoud Mofid, Ali Reza Asgari, Mehdi Hedayati, Maryam-Saddat Daneshpour · Journal of Trace Elements in Medicine and Biology · 2011
    Non-randomized trial8 participantsBoron
  24. Effect of creatine and beta-alanine supplementation on performance and endocrine responses in strength/power athletes.
    Hoffman J; Ratamess N; Kang J; Mangine G; Faigenbaum A; Stout J · International journal of sport nutrition and exercise metabolism · 2006
    Randomized trial33 participantsCreatine
  25. Long-Term Effect of Combination of Creatine Monohydrate Plus β-Hydroxy β-Methylbutyrate (HMB) on Exercise-Induced Muscle Damage and Anabolic/Catabolic Hormones in Elite Male Endurance Athletes.
    Fernández-Landa J; Fernández-Lázaro D; Calleja-González J; Caballero-García A; Córdova A; León-Guereño P; Mielgo-Ayuso J · Biomolecules · 2021
    Randomized trial28 participantsCreatine
  26. Does creatine cause hair loss? A 12-week randomized controlled trial.
    Lak M; Forbes SC; Ashtary-Larky D; Dadkhahfar S; Robati RM; Nezakati F; Khajevandi M; Naseri S; Gerafiani A; Haghighat N; Antonio J; Tinsley GM · Journal of the International Society of Sports Nutrition · 2025
    Randomized trial38 participantsCreatine
  27. Short-term creatine supplementation does not alter the hormonal response to resistance training.
    Eijnde BO; Hespel P · Medicine and science in sports and exercise · 2001
    Randomized trial11 participantsCreatine
  28. Dietary supplementation with docosahexaenoic acid rich fish oil increases circulating levels of testosterone in overweight and obese men.
    Abbott K; Burrows TL; Acharya S; Thota RN; Garg ML · Prostaglandins, leukotrienes, and essential fatty acids · 2021
    Randomized trial61 participantsFish Oil
  29. Fish oil produces an atherogenic lipid profile in hypertensive men.
    Hughes GS; Ringer TV; Watts KC; DeLoof MJ; Francom SF; Spillers CR · Atherosclerosis · 1991
    Randomized trial26 participantsFish Oil
  30. Associations of Fish Oil Supplement Use With Testicular Function in Young Men.
    Jensen TK; Priskorn L; Holmboe SA; Nassan FL; Andersson AM; Dalgård C; Petersen JH; Chavarro JE; Jørgensen N · JAMA network open · 2020
    Cross-sectional study1,679 participantsFish Oil
  31. Melatonin potentiates testosterone-induced suppression of luteinizing hormone secretion in normal men.
    Anderson RA; Lincoln GA; Wu FC · Human reproduction (Oxford, England) · 1994
    Randomized trial12 participantsMelatonin
  32. Effect of melatonin supplementation on cardiometabolic risk factors, oxidative stress and hormonal profile in PCOS patients: a systematic review and meta-analysis of randomized clinical trials.
    Ziaei S; Hasani M; Malekahmadi M; Daneshzad E; Kadkhodazadeh K; Heshmati J · Journal of ovarian research · 2024
    Meta-analysis6 studies pooledMelatonin
  33. Effects of Melatonin Supplementation on Hormonal, Inflammatory, Genetic, and Oxidative Stress Parameters in Women With Polycystic Ovary Syndrome.
    Jamilian M; Foroozanfard F; Mirhosseini N; Kavossian E; Aghadavod E; Bahmani F; Ostadmohammadi V; Kia M; Eftekhar T; Ayati E; Mahdavinia M; Asemi Z · Frontiers in endocrinology · 2020
    Randomized trial56 participantsMelatonin
  34. A pharmacological dose of melatonin increases PRL levels in males without altering those of GH, LH, FSH, TSH, testosterone or cortisol.
    Waldhauser F; Lieberman HR; Lynch HJ; Waldhauser M; Herkner K; Frisch H; Vierhapper H; Waldhäusl W; Schemper M; Wurtman RJ · Neuroendocrinology · 1987
    Clinical trial24 participantsMelatonin
  35. Melatonin administered in the afternoon decreases next-day luteinizing hormone levels in men: lack of antagonism by flumazenil.
    Luboshitzky R; Shen-Orr Z; Shochat T; Herer P; Lavie P · Journal of molecular neuroscience : MN · 2000
    Randomized trial6 participantsMelatonin
  36. Efficacy of selenium and/or N-acetyl-cysteine for improving semen parameters in infertile men: a double-blind, placebo controlled, randomized study.
    Safarinejad MR; Safarinejad S · The Journal of urology · 2009
    Randomized trial468 participantsSelenium
  37. The association between metal exposure and semen quality in Chinese males: The mediating effect of androgens.
    Liu P; Yuan G; Zhou Q; Liu Y; He X; Zhang H; Guo Y; Wen Y; Huang S; Ke Y; Chen J · Environmental pollution (Barking, Essex : 1987) · 2020
    Cross-sectional study1,136 participantsSelenium
  38. In utero and peripubertal metals exposure in relation to reproductive hormones and sexual maturation and progression among girls in Mexico City.
    Ashrap P; Sánchez BN; Téllez-Rojo MM; Basu N; Tamayo-Ortiz M; Peterson KE; Meeker JD; Watkins DJ · Environmental research · 2019
    Observational study132 participantsSelenium
  39. Relationship between serum levels of testosterone, zinc and selenium in infertile males attending fertility clinic in Nnewi, south east Nigeria.
    Oluboyo AO; Adijeh RU; Onyenekwe CC; Oluboyo BO; Mbaeri TC; Odiegwu CN; Chukwuma GO; Onwuasoanya UF · African journal of medicine and medical sciences · 2013
    Observational studySelenium
  40. EVALUATION OF MALE SEX HORMONES AND TRACE ELEMENTS IN MALE TYPE 2 DIABETIC PATIENTS ATTENDING NNAMDI AZIKIWE UNIVERSITY TEACHING HOSPITAL DIABETIC CLINICS.
    Ubajaka CF; Meludu SC; Dioka CE; Onah CE; Osuji CU; Modebe IA; Ifeadike GC; Okwara JE; Amah UK; Nnebue CC · Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria · 2015
    Cross-sectional studySelenium
  41. Efficacy of Tribulus Terrestris for the treatment of premenopausal women with hypoactive sexual desire disorder: a randomized double-blinded, placebo-controlled trial.
    Vale FBC; Zanolla Dias de Souza K; Rezende CR; Geber S · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 2018
    Randomized trial40 participantsTribulus
  42. The Effects of 6 Weeks of Tribulus terrestris L. Supplementation on Body Composition, Hormonal Response, Perceived Exertion, and CrossFit® Performance: A Randomized, Single-Blind, Placebo-Controlled Study.
    Fernández-Lázaro D; Mielgo-Ayuso J; Del Valle Soto M; Adams DP; González-Bernal JJ; Seco-Calvo J · Nutrients · 2021
    Randomized trial30 participantsTribulus
  43. Tribulus terrestris versus placebo in the treatment of erectile dysfunction and lower urinary tract symptoms in patients with late-onset hypogonadism: A placebo-controlled study.
    GamalEl Din SF; Abdel Salam MA; Mohamed MS; Ahmed AR; Motawaa AT; Saadeldin OA; Elnabarway RR · Urologia · 2019
    Randomized trial70 participantsTribulus
  44. Efficacy of Tribulus terrestris for the treatment of hypoactive sexual desire disorder in postmenopausal women: a randomized, double-blinded, placebo-controlled trial.
    de Souza KZ; Vale FB; Geber S · Menopause (New York, N.Y.) · 2018
    Randomized trial45 participantsTribulus
  45. Effect of oral administration of Tribulus terrestris extract on semen quality and body fat index of infertile men.
    Salgado RM; Marques-Silva MH; Gonçalves E; Mathias AC; Aguiar JG; Wolff P · Andrologia · 2018
    Single-arm trial65 participantsTribulus
  46. Effect of vitamin E on function of pituitary-gonadal axis in male rats and human subjects.
    Umeda F; Kato K; Muta K; Ibayashi H · Endocrinologia japonica · 1983
    Clinical trialVitamin E
  47. Can Nutrition Intake Counteract Harmful Impact of Endocrine Disruptors on Male Sex Hormones? Insights from NHANES 2013-2016.
    Nian M; Xiang J; Xu P; Tan L; Chen Z; Fang M · Bulletin of environmental contamination and toxicology · 2025
    Cross-sectional study1,455 participantsVitamin E
  48. Effect of vitamin E supplementation on cardiometabolic risk factors, inflammatory and oxidative markers and hormonal functions in PCOS (polycystic ovary syndrome): a systematic review and meta-analysis.
    Tefagh G; Payab M; Qorbani M; Sharifi F; Sharifi Y; Ebrahimnegad Shirvani MS; Pourghazi F; Atlasi R; Shadman Z; Rezaei N; Mohammadi-Vajari E; Larijani B; Ebrahimpur M · Scientific reports · 2022
    Meta-analysis12 studies pooledVitamin E
  49. Testofen, a specialised Trigonella foenum-graecum seed extract reduces age-related symptoms of androgen decrease, increases testosterone levels and improves sexual function in healthy aging males in a double-blind randomised clinical study.
    Rao A; Steels E; Inder WJ; Abraham S; Vitetta L · The aging male : the official journal of the International Society for the Study of the Aging Male · 2017
    Randomized trial120 participantsFenugreek
  50. Effect of a plant extract of fenugreek (Trigonella foenum-graecum) on testosterone in blood plasma and saliva in a double blind randomized controlled intervention study.
    Lee-Ødegård S; Gundersen TE; Drevon CA · PloS one · 2024
    Randomized trial95 participantsFenugreek
  51. Efficacy of a novel extract of fenugreek seeds in alleviating vasomotor symptoms and depression in perimenopausal women: A randomized, double-blinded, placebo-controlled study.
    Khanna A; John F; Das S; Thomas J; Rao J; Maliakel B; Im K · Journal of food biochemistry · 2021
    Randomized trial48 participantsFenugreek
  52. Beneficial effects of fenugreek glycoside supplementation in male subjects during resistance training: A randomized controlled pilot study.
    Wankhede S; Mohan V; Thakurdesai P · Journal of sport and health science · 2024
    Randomized trial60 participantsFenugreek