Methylfolate 1333 mcg DFE (800 mcg (6S)-5-Methyltetrahydrofolate) Orange Flavor

Methylfolate 1333 mcg DFE (800 mcg (6S)-5-Methyltetrahydrofolate) Orange Flavor

Country Life4.9 (887 ratings)
Format:Tablet Quantity: 60 Tablet(s) · 60 servings
Goals
$17.39 $0.28 per serving

Product analysis

94 out of 100

Methylfolate 1333 mcg DFE (800 mcg (6S)-5-Methyltetrahydrofolate) Orange Flavor provides folate that supports normal blood formation when intake is low.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality100

The folate source is clearly identified as methylfolate glucosamine salt. The form alone does not establish better health outcomes.

Ingredient Transparency100

The folate amount and specific form are disclosed. That makes the serving straightforward to identify and compare.

Value For Money100

The methylfolate serving offers good value in the available cost comparison. The form does not establish an additional benefit simply because it is clearly identified.

Customer Satisfaction83

Customer feedback is very positive across several hundred ratings. The review base gives a useful picture of satisfaction.

Product Focus75

The clearest use is meeting folate needs for normal metabolism and blood formation. The high amount does not establish extra benefit when intake is adequate or an independent hair-growth effect.

Format
Tablet
Container
60 Tablet(s)
Per serving
$0.28
Customer rating
4.9 · 887 ratings
Report analysis

Goals

Everyday Health
Impact
Highest effect
A+ Ingredient FitC PathwaysB+ EvidenceA+ Formulation Logic
Folate · 1333 mcg
Study evidence
Folate Supportive 80 studies
Hair Health
Impact
High effect
A+ Ingredient FitF PathwaysC+ EvidenceA+ Formulation Logic
Study evidence
Folate Mixed 15 studies

Ingredients

IngredientAmount per servingScore
Folate ((6S)-5-Methyltetrahydrofolate-Glucosamine Salt)
1333 mcg 92
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Sugar Free Halal Vegetarian
Report overview
A+ Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyA+ Value
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsEveryday Health forFolate
  2. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsEveryday Health forFolate
  3. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsEveryday Health forFolate
  4. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewEveryday Health forFolate
  5. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledEveryday Health forFolate
  6. Hair Loss After Metabolic and Bariatric Surgery: a Systematic Review and Meta-analysis.
    Zhang W; Fan M; Wang C; Mahawar K; Parmar C; Chen W; Yang W; Global Bariatric Research Collaborative · Obesity surgery · 2021
    Meta-analysis2,538 participants18 studies pooledHair Health forFolate
  7. Quantitative Analysis of Selected Circulating Hematological Biomarkers, Essential Minerals, Vitamins, and Thyroid Hormones in Females Affected by Hair Loss.
    Al-Fawaeir S; Al-Odat I · Diseases (Basel, Switzerland) · 2025
    Case-control study200 participantsHair Health forFolate
  8. Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer.
    Saini A; Norman AR; Cunningham D; Chau I; Hill M; Tait D; Hickish T; Iveson T; Lofts F; Jodrell D; Ross PJ; Oates J · British journal of cancer · 2003
    Randomized trialHair Health forFolate
  9. Role of oxaliplatin combined with 5-fluorouracil and folinic acid in the first- and second-line treatment of advanced colorectal cancer.
    Jonker D; Rumble RB; Maroun J; Gastrointestinal Cancer Disease Site Groupof Cancer Care Ontario’s Program in Evidence-Based Care · Current oncology (Toronto, Ont.) · 2012
    Randomized trialHair Health forFolate
  10. Phase I-II study of vinorelbine in combination with 5-fluorouracil and folinic acid as first-line chemotherapy in metastatic breast cancer: a regimen with a low subjective toxic burden.
    Nolè F; de Braud F; Aapro M; Minchella I; De Pas TM; Zampino MG; Monti S; Andreoni G; Goldhirsch A · Annals of oncology : official journal of the European Society for Medical Oncology · 1997
    Randomized trialHair Health forFolate