SAMe 200 mg

SAMe 200 mg

Protocol For Life Balance4.8 (115 ratings)
Format:Capsule Quantity: 60 Capsule(s) · 60 servings
Goals
$40.00 $0.66 per serving

Product analysis

62 out of 100

SAMe 200 mg supplies a compound used in normal metabolism, but a routine detox benefit remains uncertain.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality40

The SAMe form is clearly named. A distinct quality or absorption advantage remains uncertain.

Ingredient Transparency100

The amount and form are both stated. That makes the supplement straightforward to identify and compare.

Value For Money40

The SAMe content offers limited value for the cost. Its unclear routine benefit makes that cost relevant when comparing options.

Customer Satisfaction74

Customer feedback is very positive, though based on a relatively modest number of ratings. That provides some context on satisfaction without establishing a liver or detox benefit.

Product Focus72

A single ingredient keeps the supplement narrowly focused. Its role in normal metabolism does not establish faster routine toxin clearance.

Format
Capsule
Container
60 Capsule(s)
Per serving
$0.66
Customer rating
4.8 · 115 ratings
Report analysis

Goals

Liver & Detox
Impact
High effect
B+ Ingredient FitF PathwaysA- EvidenceA+ Formulation Logic
SAMe · 200 mg
Study evidence
SAMe Supportive 30 studies

Ingredients

IngredientAmount per servingScore
SAMe (S-Adenosyl-L-Methionine Disulfate Tosylate)
200 mg 63
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
B Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyD- Value
The serving provides 200 mg of SAMe at a somewhat high cost per 400 mg. Blister packaging is not documented. The active yield is not clearly separated from the salt weight.
How this ingredient is rated

Active Ingredient Quality & Bioavailability77

A stabilized SAMe salt is indicated, but its specific form is unclear. Protective blister packaging is not documented, so moisture protection is unclear.
Stabilized Salt Form
A stabilized SAMe salt is indicated, but its specific form is unclear.
Packaging Integrity
Protective blister packaging is not documented, so moisture protection is unclear.

Dose, Safety & Label Transparency60

A serving lists 200 mg of SAMe. The amount is not clearly distinguished as active SAMe versus salt weight.
Active Dosage Strength
A serving lists 200 mg of SAMe.
Net SAMe Yield Transparency
The amount is not clearly distinguished as active SAMe versus salt weight.

Value40

The cost per 400 mg of SAMe is somewhat high. Enteric coating or delayed release is not documented, leaving protection from stomach acid uncertain.
Price Per 400mg Active Dose
The cost per 400 mg of SAMe is somewhat high. Enteric coating or delayed release is not documented, leaving protection from stomach acid uncertain.
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Early treatment efficacy of S-adenosylmethionine in patients with intrahepatic cholestasis: A systematic review.
    Noureddin M; Sander-Struckmeier S; Mato JM · World journal of hepatology · 2020
    Systematic review9 studies pooledLiver & Detox forSAMe
  2. Ursodeoxycholic acid and S-adenosylmethionine in the treatment of intrahepatic cholestasis of pregnancy: a multi-centered randomized controlled trial.
    Zhang L; Liu XH; Qi HB; Li Z; Fu XD; Chen L; Shao Y · European review for medical and pharmacological sciences · 2016
    Randomized trial120 participantsLiver & Detox forSAMe
  3. S-adenosyl-L-methionine for the treatment of chronic liver disease: a systematic review and meta-analysis.
    Guo T; Chang L; Xiao Y; Liu Q · PloS one · 2015
    Meta-analysis705 participants11 studies pooledLiver & Detox forSAMe
  4. Protective effect of S-adenosylmethionine on hepatic ischemia-reperfusion injury during hepatectomy in HCC patients with chronic HBV infection.
    Liu GY; Wang W; Jia WD; Xu GL; Ma JL; Ge YS; Yu JH; Sun QK; Meng FL · World journal of surgical oncology · 2014
    Non-randomized trial81 participantsLiver & Detox forSAMe
  5. S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial.
    Mato JM; Cámara J; Fernández de Paz J; Caballería L; Coll S; Caballero A; García-Buey L; Beltrán J; Benita V; Caballería J; Solà R; Moreno-Otero R; Barrao F; Martín-Duce A; Correa JA; Parés A; Barrao E; García-Magaz I; Puerta JL; Moreno J; Boissard G; Ortiz P; Rodés J · Journal of hepatology · 1999
    Randomized trial123 participantsLiver & Detox forSAMe