Niacinamide 500 mg

Niacinamide 500 mg

21st Century4.6 (8,799 ratings)
Format:Tablet Quantity: 110 Tablet(s) · 110 servings
Goals
$5.49 $0.04 per serving
iHerbLowest$5.49iHerb$5.49Pure Formulas$6.45

Product analysis

61 out of 100

Niacinamide 500 mg supplies a nutrient needed for normal skin function, with the clearest benefit when intake is low. The high amount does not establish added cosmetic benefit when nutritional needs are already met.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality24

The niacin form is not clearly disclosed, while calcium carbonate is identified. The available information does not allow a firm comparison of their quality or absorption.

Ingredient Transparency81

The amounts of both ingredients are disclosed, so the serving is straightforward to compare. Calcium is identified as carbonate, but the niacin form remains unclear.

Value For Money88

The serving offers favorable value for its niacin content. Calcium adds uncertainty because there is not enough information to judge its value separately.

Customer Satisfaction87

Customer feedback is positive across a large number of ratings. That broad response is reassuring about satisfaction, but it does not establish skin or heart benefits.

Product Focus46

The formula has a clear nutritional role for skin when niacin intake is low. Its relevance to cardiovascular support is much less convincing because niacinamide does not share the evidence described for nicotinic acid.

Format
Tablet
Container
110 Tablet(s)
Per serving
$0.04
Customer rating
4.6 · 8,799 ratings
Report analysis

Goals

Skin Health
Skin Health
Impact
Moderate effect
B+ Ingredient FitF PathwaysC EvidenceA+ Formulation Logic

Niacin at 500 mg per serving supplies a nutrient needed for normal skin function. Correcting inadequate intake can matter for skin, but high amounts do not imply added cosmetic benefit in adequately nourished adults.

How this product is rated for Skin Health

Ingredient fit82

The relevant ingredients contribute through skin-related nutritional or structural roles, with the saved amount assessment varying by ingredient.
Goal fit
Skin-related ingredients sit alongside ingredients serving other functions, making the focus less direct.
Dose adequacy
The assessed amounts reach the saved comparison levels, without implying that more provides greater skin benefits.

Pathways0

The saved assessment assigns no contribution to its specified skin pathways.
Depth
None of the specified skin pathways receives a contribution in the saved finding.
Breadth
No skin area reaches the saved threshold for substantial coverage.

Evidence61

The strongest saved finding concerns vitamin b3 (niacin); practical skin benefits remain dependent on the preparation and nutritional need.
Evidence strength
Vitamin B3 (Niacin) supplies the strongest saved finding at an assessed amount; this is not a prediction of individual skin improvement.
Studied preparation
The assessed ingredients meet the saved preparation comparison.

Formulation logic100

The assessed ingredients have no missing required partner or matched conflict.
Partner coverage
No required supporting ingredient is missing for the assessed contribution.
Conflicts
No listed conflict was matched in the supplied assessment.
Effective doses
All assessed ingredients clear the saved minimum amount threshold.
Study evidence
Niacin Supportive 61 studies
Cardiovascular Support
Cardiovascular Support
Impact
Situational effect
D- Ingredient FitF PathwaysF EvidenceB Formulation Logic
Niacin · 500 mg

Niacinamide 500 mg is declared on the label, but it is not the nicotinic acid preparation linked to triglyceride-marker evidence; the supplied references give it no cardiovascular marker contribution. Calcium is also an unrelated active. As a result, no pathway or studied-dose support is established for this product. This does not show niacinamide is ineffective for every purpose.

How this product is rated for Cardiovascular Support

Ingredient fit42

The label gives a niacinamide amount, but this preparation is not credited for the cardiovascular markers described here.
Goal fit
Niacinamide is not linked to the relevant marker evidence, and calcium is off-goal.
Dose adequacy
The listed niacinamide amount cannot be used as a nicotinic acid dose.

Pathways0

No cardiovascular pathway is supported by this preparation in the supplied facts.
Depth
No pathway has relevant coverage from niacinamide here.
Breadth
None of the target pathways has credited coverage.

Evidence0

The supplied lipid-marker evidence concerns nicotinic acid, not niacinamide.
Evidence strength
No ingredient reaches a dose with evidence for these cardiovascular markers.
Studied preparation
No credited ingredient is present in a studied cardiovascular preparation.

Formulation logic75

No conflict or partner gap was identified, but the listed niacinamide gets no marker credit.
Partner coverage
No credited ingredient is shown to be missing a required partner.
Conflicts
No applicable conflict was identified in the saved facts.
Effective doses
The listed amount is for niacinamide, not the preparation used in the marker comparison.
Study evidence
Niacin Supportive 136 studies

Ingredients

IngredientAmount per servingScore
Niacinamide
500 mg 91
Calcium (Calcium Carbonate)
 160 mg
Gluten Free Adults 18–50
Report overview
Niacin · 500 mg OverallScore91
A- Active Ingredient Quality & BioavailabilityA Dose, Safety & Label TransparencyA+ Value
The serving provides 500 mg of niacin as Niacinamide at a low cost per serving. The form is named, though the amount alone does not establish an outcome.
How this ingredient is rated

Active Ingredient Quality & Bioavailability86

Niacinamide is the named niacin source.
Niacin Form & Goal Alignment
Niacinamide is the stated niacin form.
Precursor Source Quality
Niacinamide is the named source of niacin.

Dose, Safety & Label Transparency92

The niacin source is named and the serving amount is stated.
Clarity of Chemical Form
The niacin form is specified as Niacinamide.
Form-Specific Dosage Efficacy
The serving provides 500 mg of niacin.
Flush Risk & Safety Labeling
A flush warning is recorded in the available information.

Value100

The cost per serving is low.
Price Per Effective Serving
The cost per serving is low.
View ingredientView products
81 Performance

Niacinamide 500 mg

Nature's Way

A focused niacinamide capsule provides transparent non-flushing vitamin B3 with useful skin-oriented coverage. Compared with the original, it keeps a non-flushing vitamin B3 emphasis while improving dose clarity or everyday practicality; however, the amount is high for routine nutrition and does not substitute for nicotinic acid in lipid-focused use.

80 Performance

Niacinamide

Thorne

Clearly identified niacinamide provides a simple non-flushing option with strong skin-purpose alignment. Compared with the original, it keeps a non-flushing vitamin B3 emphasis while improving dose clarity or everyday practicality; however, the amount is well above basic nutritional needs and is not a direct cardiovascular niacin substitute.

82 Performance

Niacinamide 500 mg

Solaray

Clearly named niacinamide offers a non-flushing form suited more to skin and NAD metabolism than lipid management. Compared with the original, it keeps a non-flushing vitamin B3 emphasis while improving dose clarity or everyday practicality; however, the amount exceeds basic nutritional needs and long-term unsupervised use is less suitable.

86 Budget

Niacinamide B-3 100 mg

Source Naturals

A clearly identified moderate niacinamide tablet offers simple non-flushing vitamin B3 support with excellent serving economics. It is among the lowest-cost supplied choices, although it does not undercut the already inexpensive original, but it does not provide nicotinic acid’s lipid-focused effects and complete excipient details are missing.

80 Budget

Niacinamide 500 mg

Best Naturals

Clearly identified niacinamide provides a non-flushing option with useful skin and NAD-metabolism alignment. It is among the lowest-cost supplied choices, although it does not undercut the already inexpensive original, but the amount is well above basic nutritional needs and is not equivalent to nicotinic acid for lipid-focused use.

82 Budget

Niacinamide 500 mg

NOW

A simple niacinamide capsule provides clearly named non-flushing vitamin B3 with strong skin-goal alignment. It is among the lowest-cost supplied choices, although it does not undercut the already inexpensive original, but the amount remains high for routine nutrition and does not offer nicotinic acid’s lipid-related effects.

85 Value

Niacin 100 mg

Source Naturals

A moderate niacinamide tablet provides clearly identified vitamin B3 without typical nicotinic-acid flushing. Its quality-adjusted serving economics and clearer active design support practical value compared with the original, although the form is intended for nutritional or skin support rather than lipid-focused effects.

82 Value

No Flush Niacin (Inositol Hexanicotinate) 800 mg

Life Extension

Clearly named inositol hexanicotinate provides substantial flush-free niacin exposure with economical serving value. Its quality-adjusted serving economics and clearer active design support practical value compared with the original, although its cardiovascular effects may be less direct and reliable than those of nicotinic acid.

81 Value

B-Complex with Folic Acid plus Vitamin C

Nature's Bounty

A broad B-complex with vitamin C provides practical daily B-vitamin coverage at very low serving cost. Its quality-adjusted serving economics and clearer active design support practical value compared with the original, although several forms are conventional, thiamine entries are duplicated, and it is not a dedicated niacin or performance formula.

Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The current state of niacin in cardiovascular disease prevention: a systematic review and meta-regression.
    Lavigne PM; Karas RH · Journal of the American College of Cardiology · 2013
    Meta-analysis9,959 participants11 studies pooledCardiovascular Support forNiacin
  2. Effects of niacin on apo A1 and B levels: a systematic review and meta-analysis of randomised controlled trials.
    Saboori S; Yousefi Rad E; Tammam J; Thondre PS; Coe S · The British journal of nutrition · 2024
    Meta-analysis12 studies pooledCardiovascular Support forNiacin
  3. Effect of lipid-lowering therapies on lipoprotein(a) levels: a comprehensive meta-analysis of randomized controlled trials.
    Xie S; Galimberti F; Olmastroni E; Carugo S; Catapano AL; Casula M; META-LIPID Group · Atherosclerosis · 2025
    Meta-analysis145,314 participants147 studies pooledCardiovascular Support forNiacin
  4. Extended-release niacin vs gemfibrozil for the treatment of low levels of high-density lipoprotein cholesterol. Niaspan-Gemfibrozil Study Group.
    Guyton JR; Blazing MA; Hagar J; Kashyap ML; Knopp RH; McKenney JM; Nash DT; Nash SD · Archives of internal medicine · 2000
    Randomized trial173 participantsCardiovascular Support forNiacin
  5. Equivalent efficacy of a time-release form of niacin (Niaspan) given once-a-night versus plain niacin in the management of hyperlipidemia.
    Knopp RH; Alagona P; Davidson M; Goldberg AC; Kafonek SD; Kashyap M; Sprecher D; Superko HR; Jenkins S; Marcovina S · Metabolism: clinical and experimental · 1998
    Randomized trial223 participantsCardiovascular Support forNiacin
  6. The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer.
    Hakozaki T; Minwalla L; Zhuang J; Chhoa M; Matsubara A; Miyamoto K; Greatens A; Hillebrand GG; Bissett DL; Boissy RE · The British journal of dermatology · 2002
    Randomized trial138 participantsSkin Health forNiacin
  7. Niacinamide: A B vitamin that improves aging facial skin appearance.
    Bissett DL; Oblong JE; Berge CA · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2005
    Randomized trial50 participantsSkin Health forNiacin
  8. The clinical anti-aging effects of topical kinetin and niacinamide in Asians: a randomized, double-blind, placebo-controlled, split-face comparative trial.
    Chiu PC; Chan CC; Lin HM; Chiu HC · Journal of cosmetic dermatology · 2008
    Randomized trial52 participantsSkin Health forNiacin
  9. A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention.
    Chen AC; Martin AJ; Choy B; Fernández-Peñas P; Dalziell RA; McKenzie CA; Scolyer RA; Dhillon HM; Vardy JL; Kricker A; St George G; Chinniah N; Halliday GM; Damian DL · The New England journal of medicine · 2015
    Randomized trial386 participantsSkin Health forNiacin
  10. Nicotinamide for Skin Cancer Chemoprevention.
    Breglio KF; Knox KM; Hwang J; Weiss R; Maas K; Zhang S; Yao L; Madden C; Xu Y; Hartman RI; Wheless L · JAMA dermatology · 2025
    Cohort study33,822 participantsSkin Health forNiacin