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L-Glutathione Reduced 500 mg

Healthy Origins
4.3
★ ★ ★ ★ ★
(398 ratings)
Glutathione 500 mg
Product Image
Score84
500 mg of setria anchors a solid single-ingredient option with solid value. Its main trade-off is the high dose, which may be either convenient or restrictive depending on the intended routine.
How scoring works
Quantity:60 Veggie Cap(s) • (60 servings)
Goals:
Anti-Inflammatory Support

Score 84

500 mg of setria anchors a solid single-ingredient option with solid value. Its main trade-off is the high dose, which may be either convenient or restrictive depending on the intended routine.
How scoring works
$24.99($0.41 per serving)
iHerb
$ 24.99
Pure Formulas
$ 24.99
Walmart
$ 27.08
Vitacost
$ 24.99
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Analysis

The 500 mg serving provides setria as the main active in veggie cap(s). The amount gives the product a high-dose profile without adding unrelated actives.

The amount is stated, but the supplied information leaves some formulation detail unspecified. Value is reasonable, though alternatives may offer a better balance of form and quantity, and the focused formula makes comparison with similar products easier.

The strongest practical fit is anti-inflammatory support, with related assessments also supporting glutathione-focused use. The main decision is whether 500 mg and the veggie cap(s) format match the user's preferred routine and budget.

Who is it for
  • Adults seeking a high-dose Glutathione supplement
  • People who prefer veggie cap(s) for setria
  • Users focused on anti-inflammatory support
Best for
  • Anti-Inflammatory Support support

Pros

  • Clearly stated 500 mg amount
  • Focused setria formula
  • Serving amount is easy to identify
  • Simple format makes alternatives easy to compare

Cons

  • 500 mg offers little flexibility for lower-dose use
  • Veggie cap(s) may not suit every user's format preference
  • Single-active formula provides no complementary nutrients

Nutrient quality

92 Highest impact

A substantial branded reduced-glutathione amount provides strong dose quality. Plain capsule delivery remains the main limitation.

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Ingredient transparency

82 Highest impact

Active amounts are clearly disclosed without a hidden blend. Complete directions and inactive ingredients remain absent.

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Customer satisfaction

66 High impact

Customer sentiment is favorable. A substantial rating base makes the average dependable, while no narrative feedback was supplied.

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Value for money

92 Highest impact

Serving economics are reasonable. Formula quality supports excellent practical value.

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Goals

Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
High effect
B- Goal FitA- Strength of SupportC CoverageA Formula Quality
Glutathione · 500 mg

Reduced glutathione supplies direct antioxidant support that may help limit oxidative stress associated with inflammatory signaling. The 500 mg Setria amount is clearly disclosed and reaches a meaningful oral dose.

A branded purity standard improves confidence, but a standard capsule lacks liposomal or other enhanced delivery. The focused formula provides strong antioxidant depth while leaving direct enzyme and immune-signaling pathways largely uncovered.

Study evidence
Glutathione Disputed 2 studies

Ingredients

IngredientAmount per serving
Setria (L-Glutathione, Reduced)
 500 mg
Gluten Free Adults 18–50 Vegan Dairy Free Vegetarian
Report overview
Glutathione (L-Glutathione, Reduced) · 500 mg OverallScore80
C- Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA- Value

Setria supplies 500 mg of reduced glutathione with clear branded-source quality. The dose reaches the preferred range for a standard oral form, although the capsule lacks enhanced delivery. A one-capsule serving and below-median cost create strong practical value.

View ingredientView products
Loading alternative details
83 Performance

Glutathione Reduced 500 mg

Jarrow Formulas
<p>Its label clearly provides 500 mg of Glutathione, making it a more clearly defined glutathione option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
75 Performance

Glutathione 200 mg

Vital Nutrients
<p>Its label clearly provides 400 mg of reduced Glutathione as Setria Glutathione, making it a more clearly defined glutathione option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
65 Performance

Brocco-Glutathione

Nature's Answer
<p>Its label clearly provides 1000 mg of Setria Glutathione, making it a more clearly defined glutathione option. Compared with the original, its ingredient and goal alignment is stronger, although the input does not provide independent testing or absorption evidence.</p>
82 Budget

L-Glutathione 100 mg

Swanson
<p>Its label clearly provides 100 mg of Setria Glutathione as L-Glutathione, preserving relevant glutathione coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
77 Budget

Supplemelts Sublingual L-Glutathione Natural Orange Flavor 50 mg

Swanson Ultra
<p>Its label clearly provides 50 mg of Setria Glutathione as L-Glutathione, preserving relevant glutathione coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
82 Budget

Glutathione 250 mg

NOW
<p>Its label clearly provides 250 mg of Glutathione, preserving relevant glutathione coverage. Compared with the original, it lowers the serving cost, although the input does not provide independent testing or absorption evidence.</p>
83 Value

High Potency L-Glutathione 200 mg

Swanson Ultra
<p>Its label clearly provides 200 mg of Setria Glutathione as L-Glutathione, keeping the formula relevant to glutathione. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
82 Value

Reduced L-Glutathione 250 mg

Solgar
<p>Its label clearly provides 250 mg of L-Glutathione, keeping the formula relevant to glutathione. Compared with the original, the somewhat higher serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
85 Value

Glutathione 500 mg

NOW
<p>Its label clearly provides 500 mg of Glutathione, Reduced, keeping the formula relevant to glutathione. Compared with the original, the lower serving cost and ingredient detail create a useful quality-to-cost balance, although the input does not provide independent testing or absorption evidence.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Serum type III procollagen, procollagen V, tumour necrosis factor-a, interleukin-6 in liver cirrhosis after antiviral treatment.
    Li W; Liu X; Bi F · Journal of medical biochemistry · 2025
    Randomized trial92 participantsAnti-Inflammatory Support forGlutathione
  2. Evaluation of the antioxidant and anti-inflammatory effect of sublingual glutathione on COPD patients.
    Farag A; Abass W; Qassem H · Journal of medicine and life · 2024
    Cohort study50 participantsAnti-Inflammatory Support forGlutathione