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Glutathione 500 mg

NOW
4.6
★ ★ ★ ★ ★
(57235 ratings)
Glutathione 500 mg
Milk Thistle 100 mg
Product Image
Score85
A strong reduced-glutathione capsule with milk thistle and good value, limited by ordinary delivery and a minor label ambiguity.
How scoring works
Quantity:120 Capsule(s) • (120 servings)
Goals:
Anti-Inflammatory Support

Score 85

A strong reduced-glutathione capsule with milk thistle and good value, limited by ordinary delivery and a minor label ambiguity.
How scoring works

Also available as

2 options
60 servings Milk Thistle 100 mg, Glutathione 500 mg • 60 Capsule(s) • 60 servings $23.21 ($0.38 per serving) 30 servings Milk Thistle 100 mg, Glutathione 500 mg • 30 Capsule(s) • 30 servings $13.90 ($0.46 per serving)
$37.30($0.31 per serving)
iHerb
$ 47.76
Daily Vita
$ 45.10
Vitacost
$ 47.76
Amazon
$ 37.30
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Analysis

Each capsule provides 500 mg reduced glutathione, 100 mg milk thistle extract, and 50 mg alpha-lipoic acid. The combination offers clear antioxidant and liver-support roles without a proprietary blend.

Milk thistle appears in paired fruit and seed lines at the same amount, which likely describes one extract but creates minor label ambiguity. Glutathione uses conventional capsule delivery rather than a liposomal or otherwise enhanced format.

The large supply provides good routine value for users who want oral glutathione. The formula supports antioxidant nutrition rather than directly treating inflammation.

Who is it for
  • Adults seeking reduced glutathione
  • People wanting glutathione with milk thistle
Best for
  • Long-term antioxidant routines
  • Liver-focused nutrient support

Pros

  • Provides 500 mg reduced glutathione
  • Includes milk thistle and alpha-lipoic acid
  • Large supply supports good value

Cons

  • No enhanced glutathione delivery
  • Milk thistle lines are ambiguous
  • Alpha-lipoic acid amount is modest

Warnings

  • Alpha-lipoic acid may add to glucose-lowering effects of insulin and diabetes medicines.

Nutrient quality

92 Highest impact

Reduced glutathione is clearly specified, while milk thistle lacks active standardization and delivery is conventional. Glutathione is meaningfully dosed, with milk thistle and alpha-lipoic acid serving as modest supports.

Ingredient transparency

82 Highest impact

All active ingredients have clear individual amounts. Excipients and daily directions are absent from the supplied data, which leaves some label details uncertain.

Customer satisfaction

70 High impact

The aggregate satisfaction average is favorable, though no detailed feedback is supplied. The very large volume makes the aggregate satisfaction signal stable.

Value for money

96 Highest impact

A strong core dose and appropriate supporting ingredients justify the formula well. The serving offers excellent cost efficiency for reduced glutathione.

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Goals

Anti-Inflammatory Support
Anti-Inflammatory Support
Impact
Highest effect
B Goal FitA- Strength of SupportB CoverageA- Formula Quality
Glutathione · 500 mg

Reduced glutathione at a substantial disclosed dose gives the formula a strong antioxidant foundation for managing oxidative stress linked with inflammatory signaling. Milk thistle and alpha-lipoic acid add complementary antioxidant and glutathione-recycling support.

The standard capsule lacks specialized delivery technology, so absorption is less certain than with enhanced glutathione forms. Alpha-lipoic acid may add to the effects of insulin or other glucose-lowering medicines, which can increase the risk of low blood sugar.

Study evidence
Glutathione Disputed 2 studies

Ingredients

IngredientAmount per serving
Glutathione, Reduced
500 mg
Milk Thistle Fruit, Seed Extract (Silybum marianum Fruit Extract, Silybum marianum Seed Extract)
 100 mg
Alpha-Lipoic Acid
50 mg
Adults 18–50 Vegan Kosher Dairy Free Halal Vegetarian
Report overview
Glutathione · 500 mg OverallScore75
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyA+ Value

The clearly identified reduced form provides a high 500 mg dose, but a plain capsule offers only standard absorption. The one-capsule serving is transparent and delivers exceptional cost efficiency for the amount. Alpha-lipoic acid may add to glucose-lowering effects, so people using insulin or other diabetes medicines should monitor for low blood sugar.

View ingredientView products
Milk Thistle (Silybum marianum Fruit Extract, Silybum marianum Seed Extract) · 100 mg OverallScore28
D- Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyC Value

A 100 mg fruit and seed extract is disclosed, but no silymarin standardization or active yield is given. The dry capsule lacks absorption-enhancing technology. The serving cost is below the collection norm, though potency is unclear.

View ingredientView products
Loading alternative details
80 Performance

Glutathione 500 mg

NOW
<p>Compared with the original, it retains Milk Thistle, and Glutathione and remains aligned with anti-inflammatory support. A substantial glutathione amount with milk thistle and alpha-lipoic acid creates a focused antioxidant formula at favorable value. The glutathione state and milk-thistle standardization are not specified, so absorption and supporting potency remain uncertain.</p>
84 Performance

L-Glutathione Reduced 500 mg

Healthy Origins
<p>Compared with the original, it retains Glutathione and remains aligned with anti-inflammatory support. A substantial branded reduced-glutathione amount provides strong dose and source quality. Comparatively mixed customer sentiment contrasts with economical servings and excellent formula value.</p>
83 Performance

Glutathione Reduced 500 mg

Jarrow Formulas
<p>Compared with the original, it retains Glutathione and remains aligned with anti-inflammatory support. A substantial reduced-glutathione amount provides strong antioxidant depth. Extensive customer evidence is mixed, while favorable serving economics support good value.</p>
82 Budget

Glutathione 250 mg

NOW
<p>It lowers recurring cost while retaining Glutathione from the original's ingredient focus. A meaningful glutathione amount provides focused antioxidant support at favorable serving value. Extensive customer evidence supports good practical value despite that limitation.</p>
77 Budget

Milk Thistle 30:1 Extract

Jarrow Formulas
<p>It lowers recurring cost while retaining Milk Thistle from the original's ingredient focus. A concentrated milk thistle extract uses relevant seed and fruit sourcing and offers especially accessible serving value. The focused design is appealing, though repeated label entries and incomplete active-flavonoid detail keep potency somewhat uncertain.</p>
84 Budget

Milk Thistle

Kroeger Herb Products Co.
<p>It lowers recurring cost while retaining Milk Thistle from the original's ingredient focus. A separate silymarin amount from milk thistle seed makes potency unusually easy to assess. Favorable serving value and a sizeable aggregate customer base strengthen the case.</p>
78 Value

Glutathione 500 mg

NOW
<p>It retains Milk Thistle, and Glutathione, but the supplied cost data does not establish a cheaper serving than the original. A substantial glutathione amount with milk thistle and alpha-lipoic acid creates a focused antioxidant formula. The glutathione state and milk-thistle standardization are not specified, and this package offers only moderate value compared with larger versions.</p>
85 Value

Milk Thistle

Paradise
<p>It combines a lower recurring cost with Milk Thistle, supporting a practical value case against the original. A substantial stated silymarin amount provides focused milk thistle potency in a simple formula. Strong aggregate customer metrics and favorable serving value make it competitive among conventional options.</p>
82 Value

L-Glutathione 100 mg

Swanson
<p>It combines a lower recurring cost with Glutathione, supporting a practical value case against the original. Branded Setria glutathione supports ingredient confidence at a modest amount. Extensive customer evidence and exceptionally economical servings support good value.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Serum type III procollagen, procollagen V, tumour necrosis factor-a, interleukin-6 in liver cirrhosis after antiviral treatment.
    Li W; Liu X; Bi F · Journal of medical biochemistry · 2025
    Randomized trial92 participantsAnti-Inflammatory Support forGlutathione
  2. Evaluation of the antioxidant and anti-inflammatory effect of sublingual glutathione on COPD patients.
    Farag A; Abass W; Qassem H · Journal of medicine and life · 2024
    Cohort study50 participantsAnti-Inflammatory Support forGlutathione