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Men's Bladder Control

Life Extension
4.0
★ ★ ★ ★ ★
(758 ratings)
Boron 10 mg
Lycopene 15 mg
Melatonin 2 mg
Product Image
Score80
Focused bladder and prostate support with strong ingredient disclosure. Added melatonin makes it bedtime-specific and less flexible for daytime users.
How scoring works
Quantity:30 Capsule(s) • (30 servings)
Goals:
General Health
Testosterone Support
Skin Health
Sleep Support

Score 80

Focused bladder and prostate support with strong ingredient disclosure. Added melatonin makes it bedtime-specific and less flexible for daytime users.
How scoring works
$20.00($0.66 per serving)
iHerb
$ 20.00
Walmart
$ 20.00
Vitacost
$ 20.03
Amazon
$ 20.00
Pure Formulas
$ 20.00
Report prices

Analysis

Beta-sitosterol and pygeum provide the main bladder and prostate rationale, while 15 mg lycopene and 10 mg chelated boron add useful supporting pathways. The active amounts and forms are clearly disclosed.

The 2 mg melatonin amount makes nighttime use logical and may help sleep timing. It also means the formula is not a neutral daytime bladder product, and the high boron amount may be more than someone seeking simple maintenance needs.

The product best fits adult men who want targeted bladder support and can take the capsule before bed. People who drive at night, work shifts, or already use melatonin may find the fixed combination inconvenient.

Who is it for
  • Adult men seeking bladder and prostate support
  • People who prefer bedtime dosing
  • Users wanting beta-sitosterol, pygeum, and lycopene together
Best for
  • Nighttime bladder-support routines
  • Prostate-focused supplementation
  • Users who also want melatonin

Pros

  • Meaningful beta-sitosterol and pygeum amounts
  • Premium lycopene and chelated boron forms
  • Clear active-dose disclosure

Cons

  • Melatonin limits daytime use
  • Boron dose is high for basic maintenance
  • Narrower than a general men’s-health formula

Warnings

  • Melatonin may cause next-day drowsiness and should not be taken before driving or safety-sensitive work
  • The 10 mg boron amount should be counted when using other boron products
  • Beta-sitosterol and pygeum may affect urinary symptoms that warrant medical evaluation rather than self-treatment

Nutrient quality

86 Highest impact

Branded lycopene, chelated boron, and targeted prostate ingredients support a purposeful formula. Substantial boron and the daytime drowsiness risk from melatonin require careful timing and suitability.

Ingredient transparency

86 Highest impact

Every listed active has a specific amount and no proprietary blend obscures the formula. Missing non-active ingredients, full timing directions, and some botanical standards leave disclosure incomplete.

Customer satisfaction

65 Moderate impact

The supplied average is mixed and supported by substantial response volume. No comment-level evidence is available to assess repeated complaints or alignment with the intended use.

Value for money

76 High impact

Several targeted actives and premium nutrient forms support reasonable serving value. Timing constraints and a mixed supplied average prevent a stronger competitive conclusion.

Report analysis

Goals

General Health
General Health
Impact
High effect
C Goal FitA- Strength of SupportB- CoverageB- Formula Quality
Boron · 10 mg

Chelated boron provides relevant support for mineral metabolism, while melatonin may help circadian timing in specific situations. Beta-sitosterol, pygeum, and lycopene make the formula primarily a targeted bladder and prostate product rather than broad daily wellness support.

Most forms and amounts are clearly disclosed, including a substantial boron serving and a physiological melatonin amount. The melatonin can cause drowsiness and reduced alertness if the capsule is taken during the day or before driving.

Study evidence
Boron Supportive 6 studies
Melatonin Supportive 69 studies
Testosterone Support
Testosterone Support
Impact
High effect
C+ Goal FitA Strength of SupportD+ CoverageF Formula Quality
Melatonin · 2 mgBoron · 10 mg

Boron at 10 mg may support free testosterone markers, while the remaining actives are mainly directed toward bladder, prostate, or sleep concerns. The boron amount is clearly disclosed and uses a chelated form.

Multiple ingredients create some indirect pathway coverage but do not form a focused testosterone formula. Beta-sitosterol and pygeum make the product better suited to its bladder purpose than to endocrine support.

Study evidence
Boron Disputed 3 studies
Melatonin No effect 6 studies
Skin Health
Skin Health
Impact
High effect
B- Goal FitA- Strength of SupportC- CoverageF Formula Quality
Lycopene · 15 mg

Lycopene provides the formula’s only strong skin-relevant contribution through antioxidant and internal photoprotection support. The premium tomato-derived source and substantial amount make that pathway meaningful.

Beta-sitosterol, pygeum, boron, and melatonin serve a bladder-focused purpose rather than skin structure or hydration. The 2 mg melatonin may cause daytime drowsiness or impair driving when the capsule is taken during waking hours.

Study evidence
Lycopene Supportive 20 studies
Sleep Support
Sleep Support
Impact
Moderate effect
C+ Goal FitB+ Strength of SupportD CoverageD- Formula Quality
Melatonin · 2 mg

The 2 mg melatonin amount can support sleep timing and may help users who take the bladder formula at night. Most other ingredients target urinary and prostate support rather than sleep.

The formula does not address relaxation or sleep maintenance as a primary design goal. Melatonin can cause drowsiness and impaired alertness if this bladder product is taken during the day.

Study evidence
Melatonin Supportive 181 studies

Ingredients

IngredientAmount per serving
Beta-Sitosterol
180 mg
Pygeum extract
100 mg
Lycopene (LycoBeads)
 15 mg
Boron (Albion Bororganic Glycine)
 10 mg
Melatonin
2 mg
Men 18–50
Report overview
Boron (Albion Bororganic Glycine) · 10 mg OverallScore83
A+ Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyC Value

Albion Bororganic Glycine supplies a premium chelated source with strong quality disclosure. The 10 mg amount is evidence-aligned but high for routine long-term use, so people seeking only basic maintenance may prefer a lower dose. Boron-specific value is fair within this broader bladder-support formula, which also includes melatonin.

View ingredientView products
Lycopene (LycoBeads) · 15 mg OverallScore68
C+ Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyC Value

LycoBeads supplies a premium 15 mg lycopene dose with clear source identity. Dry-capsule delivery lacks an oil carrier, and the label does not describe accompanying tomato phytonutrients. The 2 mg melatonin can cause drowsiness, so daytime use may impair alertness or driving.

View ingredientView products
Melatonin · 2 mg OverallScore58
F Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value

The 2 mg dose aligns with physiological use and is clearly supplied in one capsule. Standard immediate-release delivery may support sleep onset but does not target sleep maintenance. Because the formula is intended for bladder support, its melatonin can cause drowsiness and may impair alertness if taken during the day.

View ingredientView products
Loading alternative details
77 Performance

Ultra Prostate Formula

Life Extension
<p>Broader prostate-focused coverage makes this the strongest ingredient match in the eligible pool. Standardized saw palmetto, beta-sitosterol, pygeum, nettle, pumpkin oil, lycopene, and boron add multiple relevant pathways without relying on melatonin.</p>
76 Performance

ProstAid+

Advanced Nutrition by Zahler
<p>Branded lycopene, phytosterols, lignans, zinc, selenium, and active-form vitamin B6 provide a well-defined prostate and antioxidant blend. The lower boron amount and lack of melatonin reduce two practical concerns, although beta-sitosterol and pygeum are absent.</p>
70 Performance

Prostate Health

21st Century
<p>Plant sterols, pumpkin seed oil, saw palmetto, pygeum, lycopene, boron, zinc, and vitamin D create broader prostate-oriented coverage. Several key amounts are modest or undercharacterized, so it is broader rather than clearly more potent.</p>
70 Budget

Prostate Health

21st Century
<p>Lower serving cost and a mix of plant sterols, pumpkin seed oil, saw palmetto, pygeum, lycopene, and boron provide broader prostate-oriented coverage. Its lycopene, boron, and pygeum amounts are lighter, so the savings come with a potency trade-off.</p>
76 Budget

ProstAid+

Advanced Nutrition by Zahler
<p>The supplied candidate pool does not contain three lower-cost choices, and this option is not cheaper per serving. Branded lycopene, sterols, lignans, zinc, selenium, and a lower boron amount avoid the original's melatonin-related drowsiness concern, but ongoing value is weaker.</p>
77 Budget

Ultra Prostate Formula

Life Extension
<p>The supplied candidate pool does not contain three lower-cost choices, and this formula costs more per serving. Standardized saw palmetto, beta-sitosterol, pygeum, branded lycopene, and several complementary botanicals provide considerably broader prostate support for the added cost.</p>
70 Value

Prostate Health

21st Century
<p>Lower serving cost combines with a wide set of prostate-oriented ingredients, including plant sterols, pumpkin seed oil, saw palmetto, pygeum, lycopene, and boron. The lighter amounts limit depth, but the broader formula offers useful value for budget-focused use.</p>
77 Value

Ultra Prostate Formula

Life Extension
<p>Standardized saw palmetto plus beta-sitosterol, pygeum, nettle, pumpkin oil, lycopene, and boron justify much of the higher serving cost through substantially broader coverage. A small proprietary blend and incomplete active-marker details remain limitations.</p>
76 Value

ProstAid+

Advanced Nutrition by Zahler
<p>The eligible pool provides no third candidate with stronger cost efficiency, so this is a quality-led rather than budget-led choice. Branded lycopene, sterols, lignans, zinc, selenium, and active-form vitamin B6 offer good ingredient definition, but ongoing value trails the original.</p>
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Meta-analysis: melatonin for the treatment of primary sleep disorders.
    Ferracioli-Oda E; Qawasmi A; Bloch MH · PloS one · 2013
    Meta-analysis1,683 participants19 studies pooledSleep Support forMelatonin
  2. Exogenous melatonin as a treatment for secondary sleep disorders: A systematic review and meta-analysis.
    Li T; Jiang S; Han M; Yang Z; Lv J; Deng C; Reiter RJ; Yang Y · Frontiers in neuroendocrinology · 2019
    Meta-analysis205 participants7 studies pooledSleep Support forMelatonin
  3. Efficacy of melatonin with behavioural sleep-wake scheduling for delayed sleep-wake phase disorder: A double-blind, randomised clinical trial.
    Sletten TL; Magee M; Murray JM; Gordon CJ; Lovato N; Kennaway DJ; Gwini SM; Bartlett DJ; Lockley SW; Lack LC; Grunstein RR; Rajaratnam SMW; Delayed Sleep on Melatonin (DelSoM) Study Group · PLoS medicine · 2019
    Randomized trial116 participantsSleep Support forMelatonin
  4. Melatonin treatment for age-related insomnia.
    Zhdanova IV; Wurtman RJ; Regan MM; Taylor JA; Shi JP; Leclair OU · The Journal of clinical endocrinology and metabolism · 2001
    Randomized trial30 participantsSleep Support forMelatonin
  5. Efficacy on sleep parameters and tolerability of melatonin in individuals with sleep or mental disorders: A systematic review and meta-analysis.
    Salanitro M; Wrigley T; Ghabra H; de Haan E; Hill CM; Solmi M; Cortese S · Neuroscience and biobehavioral reviews · 2022
    Meta-analysis1,998 participants34 studies pooledSleep Support forMelatonin
  6. Effects of Melatonin Treatment on Perioperative Sleep Quality: A Systematic Review and Meta-Analysis with Trial Sequential Analysis of Randomized Controlled Trials.
    Gao Y; Chen X; Zhou Q; Song J; Zhang X; Sun Y; Yu M; Li Y · Nature and science of sleep · 2022
    Meta-analysis725 participants10 studies pooledSleep Support forMelatonin
  7. Effects of melatonin on postoperative sleep quality: a systematic review, meta-analysis, and trial sequential analysis.
    Tsukinaga A; Mihara T; Takeshima T; Tomita M; Goto T · Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Meta-analysis516 participants8 studies pooledSleep Support forMelatonin
  8. Unintended consequences: college students' melatonin usage, sleep disturbance, and depressive symptoms.
    Peltz JS; Rogge R · Sleep and biological rhythms · 2025
    Cohort study331 participantsSleep Support forMelatonin
  9. Effects of boron supplementation on the severity and duration of pain in primary dysmenorrhea.
    Nikkhah S; Dolatian M; Naghii MR; Zaeri F; Taheri SM · Complementary therapies in clinical practice · 2015
    Randomized trial113 participantsGeneral Health forBoron
  10. Efficacy and safety of tavaborole topical solution, 5%, a novel boron-based antifungal agent, for the treatment of toenail onychomycosis: Results from 2 randomized phase-III studies.
    Elewski BE; Aly R; Baldwin SL; González Soto RF; Rich P; Weisfeld M; Wiltz H; Zane LT; Pollak R · Journal of the American Academy of Dermatology · 2015
    Randomized trialGeneral Health forBoron
  11. The efficacy and safety of tavaborole, a novel, boron-based pharmaceutical agent: phase 2 studies conducted for the topical treatment of toenail onychomycosis.
    Toledo-Bahena ME; Bucko A; Ocampo-Candiani J; Herz-Ruelas ME; Jones TM; Jarratt MT; Pollak RA; Zane LT · Journal of drugs in dermatology : JDD · 2015
    Clinical trial336 participantsGeneral Health forBoron
  12. Boron neutron capture therapy (BNCT) for glioblastoma multiforme: a phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA).
    Henriksson R; Capala J; Michanek A; Lindahl SA; Salford LG; Franzén L; Blomquist E; Westlin JE; Bergenheim AT; Swedish Brain Tumour Study Group · Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2009
    Single-arm trial30 participantsGeneral Health forBoron
  13. Effects of Calcium Fructoborate on Levels of C-Reactive Protein, Total Cholesterol, Low-Density Lipoprotein, Triglycerides, IL-1β, IL-6, and MCP-1: a Double-blind, Placebo-controlled Clinical Study
    Otilia-Constantina Rogoveanu, George Dan Mogosanu, Cornelia Bejenaru, Ludovic Everard Bejenaru, Octavian Croitoru, Johny Neamtu, Zbigniew Pietrzkowski, Tania Reyes-Izquierdo, Andrei Bita, Iulia Daria Scorei, Romulus Ion Scorei · Biological Trace Element Research · 2015
    Randomized trial78 participantsGeneral Health forBoron
  14. Melatonin for preventing and treating jet lag.
    Herxheimer A; Petrie KJ · The Cochrane database of systematic reviews · 2001
    Systematic review10 studies pooledGeneral Health forMelatonin
  15. Pediatric Prolonged-Release Melatonin for Sleep in Children with Autism Spectrum Disorder: Impact on Child Behavior and Caregiver's Quality of Life.
    Schroder CM; Malow BA; Maras A; Melmed RD; Findling RL; Breddy J; Nir T; Shahmoon S; Zisapel N; Gringras P · Journal of autism and developmental disorders · 2019
    Randomized trial125 participantsGeneral Health forMelatonin
  16. Effect of melatonin supplementation on sleep quality: a systematic review and meta-analysis of randomized controlled trials.
    Fatemeh G; Sajjad M; Niloufar R; Neda S; Leila S; Khadijeh M · Journal of neurology · 2022
    Meta-analysis23 studies pooledGeneral Health forMelatonin
  17. Efficacy of melatonin for chronic insomnia: Systematic reviews and meta-analyses.
    Choi K; Lee YJ; Park S; Je NK; Suh HS · Sleep medicine reviews · 2022
    Meta-analysis24 studies pooledGeneral Health forMelatonin
  18. Effectiveness of melatonin for the treatment of nocturia: a randomized controlled trial.
    Leerasiri P; Pariyaeksut P; Hengrasmee P; Asumpinwong C · International urogynecology journal · 2023
    Randomized trial60 participantsGeneral Health forMelatonin
  19. Systemic and skin-targeting beneficial effects of lycopene-enriched ice cream: A pilot study.
    Chernyshova MP; Pristenskiy DV; Lozbiakova MV; Chalyk NE; Bandaletova TY; Petyaev IM · Journal of dairy science · 2019
    Randomized trialSkin Health forLycopene
  20. Topical lycopene emulgel significantly improves biophysical parameters of human skin.
    Sohail M; Muhammad Faran Ashraf Baig M; Akhtar N; Chen Y; Xie B; Li B · European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V · 2022
    Clinical trialSkin Health forLycopene
  21. Supplementation with tomato-based products increases lycopene, phytofluene, and phytoene levels in human serum and protects against UV-light-induced erythema.
    Aust O; Stahl W; Sies H; Tronnier H; Heinrich U · International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition · 2005
    Randomized trialSkin Health forLycopene
  22. Association of Vitamin A Intake With Cutaneous Squamous Cell Carcinoma Risk in the United States.
    Kim J; Park MK; Li WQ; Qureshi AA; Cho E · JAMA dermatology · 2024
    Cohort study123,570 participantsSkin Health forLycopene
  23. β-Carotene and other carotenoids in protection from sunlight.
    Stahl W; Sies H · The American journal of clinical nutrition · 2013
    Narrative reviewSkin Health forLycopene
  24. The Effectiveness of Melatonin for Sleep Disturbances in Parkinson' Disease: Systematic Review and Meta-Analysis.
    Yousef O; Abouelmagd ME; Khaddam H; Shbani A; Yousef R; Meshref M; Hanafi I · Journal of sleep research · 2026
    Meta-analysis409 participants8 studies pooledSleep Support forMelatonin
  25. Nightly treatment of primary insomnia with prolonged release melatonin for 6 months: a randomized placebo controlled trial on age and endogenous melatonin as predictors of efficacy and safety.
    Wade AG; Ford I; Crawford G; McConnachie A; Nir T; Laudon M; Zisapel N · BMC medicine · 2010
    Randomized trial791 participantsSleep Support forMelatonin
  26. Effects of exogenous melatonin on sleep: a meta-analysis.
    Brzezinski A; Vangel MG; Wurtman RJ; Norrie G; Zhdanova I; Ben-Shushan A; Ford I · Sleep medicine reviews · 2005
    Meta-analysis284 participants8 studies pooledSleep Support forMelatonin
  27. Biochemical and physiologic consequences of boron deprivation in humans.
    Nielsen FH · Environmental health perspectives · 1995
    Single-arm trial12 participantsTestosterone Support forBoron
  28. Plasma boron and the effects of boron supplementation in males.
    Green NR; Ferrando AA · Environmental health perspectives · 1995
    Randomized trial19 participantsTestosterone Support forBoron
  29. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
    Mohammad Reza Naghii, Mahmoud Mofid, Ali Reza Asgari, Mehdi Hedayati, Maryam-Saddat Daneshpour · Journal of Trace Elements in Medicine and Biology · 2011
    Non-randomized trial8 participantsTestosterone Support forBoron
  30. Melatonin potentiates testosterone-induced suppression of luteinizing hormone secretion in normal men.
    Anderson RA; Lincoln GA; Wu FC · Human reproduction (Oxford, England) · 1994
    Randomized trial12 participantsTestosterone Support forMelatonin
  31. Effect of melatonin supplementation on cardiometabolic risk factors, oxidative stress and hormonal profile in PCOS patients: a systematic review and meta-analysis of randomized clinical trials.
    Ziaei S; Hasani M; Malekahmadi M; Daneshzad E; Kadkhodazadeh K; Heshmati J · Journal of ovarian research · 2024
    Meta-analysis6 studies pooledTestosterone Support forMelatonin
  32. Effects of Melatonin Supplementation on Hormonal, Inflammatory, Genetic, and Oxidative Stress Parameters in Women With Polycystic Ovary Syndrome.
    Jamilian M; Foroozanfard F; Mirhosseini N; Kavossian E; Aghadavod E; Bahmani F; Ostadmohammadi V; Kia M; Eftekhar T; Ayati E; Mahdavinia M; Asemi Z · Frontiers in endocrinology · 2020
    Randomized trial56 participantsTestosterone Support forMelatonin
  33. A pharmacological dose of melatonin increases PRL levels in males without altering those of GH, LH, FSH, TSH, testosterone or cortisol.
    Waldhauser F; Lieberman HR; Lynch HJ; Waldhauser M; Herkner K; Frisch H; Vierhapper H; Waldhäusl W; Schemper M; Wurtman RJ · Neuroendocrinology · 1987
    Clinical trial24 participantsTestosterone Support forMelatonin
  34. Melatonin administered in the afternoon decreases next-day luteinizing hormone levels in men: lack of antagonism by flumazenil.
    Luboshitzky R; Shen-Orr Z; Shochat T; Herer P; Lavie P · Journal of molecular neuroscience : MN · 2000
    Randomized trial6 participantsTestosterone Support forMelatonin