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Standardized Milk Thistle 240 mg

4.7
★ ★ ★ ★ ★
(1933 ratings)
Milk Thistle 240 mg
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Score57
Long-term cost is appealing, but missing potency data and a concealed blend keep the formula from being a dependable choice.
How scoring works
Capsule
Quantity:250 Capsule(s) • (125 servings)
Goals:
Detoxification

Score 57

Long-term cost is appealing, but missing potency data and a concealed blend keep the formula from being a dependable choice.
How scoring works
$20.74($0.16 per serving)
iHerb
$ 20.74
Amazon
$ 48.28
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Analysis

Milk thistle is well aligned with normal liver antioxidant support, and silymarin is identified as the extract form. The stated weight alone does not show whether the active-marker amount is meaningful.

Half of the listed active material is an XTRA Premium Blend with no ingredient breakdown. Hidden components make the formula difficult to evaluate for usefulness, overlap, or tolerability.

A high capsule count and low serving cost improve convenience for regular users. Better value on paper cannot compensate fully for an extract that lacks a measurable active yield.

Who is it for
  • Frequent milk thistle users seeking a large supply
  • Budget-focused adults
  • People who accept limited label detail
Best for
  • Long-duration supplementation
  • Basic liver-support routines
  • Reducing reorder frequency

Pros

  • Large supply
  • Low serving cost
  • Silymarin form is named

Cons

  • No active-marker percentage
  • Proprietary blend is fully undisclosed
  • No stated absorption feature

Warnings

  • Milk thistle may cause nausea, gas, or loose stools in sensitive users.
  • People allergic to ragweed, daisies, or related plants may also react to milk thistle.
  • Milk thistle may affect blood-sugar control; people using insulin or glucose-lowering medicine should check with their prescriber.

Nutrient quality

56 Moderate impact

Silymarin is relevant, but missing standardization limits confidence in its form quality. Uncertain active yield and a large unnamed blend weaken dose quality and formula focus.

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Ingredient transparency

41 Lower impact

The milk thistle and total blend amounts are stated, but the blend conceals its individual actives. Missing intake directions and inactive-ingredient details further limit label clarity.

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Customer satisfaction

71 High impact

The average rating is positive, and the available feedback volume provides useful confidence. No specific experience details are supplied to assess recurring complaints or purpose fit.

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Value for money

68 High impact

Economical long-term use supports good practical value. The opaque blend and unknown silymarin yield keep the value from being fully convincing.

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Report analysis

Goals

Detoxification
Impact
Moderate effect
B+ Goal FitC- Strength of SupportD CoverageC Formula Quality
Milk Thistle · 240 mg

A stated silymarin extract directly supports liver-cell protection and antioxidant defenses. Human evidence for milk thistle is relevant, though results depend on a sufficiently characterized silymarin dose.

The label gives a milk thistle amount but does not state the active silymarin yield or plant part. An equally sized proprietary blend hides its ingredients, reducing confidence in dose quality, pathway coverage, and efficiency.

Study evidence
Milk Thistle Supportive 46 studies

Ingredients

IngredientAmount per serving
Milk Thistle extract (Silymarin)
240 mg
XTRA Premium Blend
240 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free Women
Report overview
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyA+ Value

The dry format provides no stated absorption advantage. The source plant part and active-marker yield remain unclear. The serving cost is well justified by the stated format or positioning.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury.
    Shahsavari K; Ardekani SS; Ardekani MRS; Esfahani MM; Kazemizadeh H; Jamialahmadi T; Iranshahi M; Khanavi M; Hasanpour M · BMC complementary medicine and therapies · 2025
    Meta-analysis3,545 participants55 studies pooledDetoxification forMilk Thistle
  2. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle
  3. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  4. A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury.
    Luangchosiri C; Thakkinstian A; Chitphuk S; Stitchantrakul W; Petraksa S; Sobhonslidsuk A · BMC complementary and alternative medicine · 2016
    Randomized trial55 participantsDetoxification forMilk Thistle
  5. Effect of 8 Weeks milk thistle powder (silymarin extract) supplementation on fatty liver disease in patients candidates for bariatric surgery.
    Mirhashemi SH; Hakakzadeh A; Yeganeh FE; Oshidari B; Rezaee SP · Metabolism open · 2022
    Observational studyDetoxification forMilk Thistle
  6. A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis.
    El-Kamary SS; Shardell MD; Abdel-Hamid M; Ismail S; El-Ateek M; Metwally M; Mikhail N; Hashem M; Mousa A; Aboul-Fotouh A; El-Kassas M; Esmat G; Strickland GT · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2009
    Randomized trial105 participantsDetoxification forMilk Thistle
  7. Evaluation of Hepatoprotective Effect of Silymarin Among Under Treatment Tuberculosis Patients: A Randomized Clinical Trial.
    Marjani M; Baghaei P; Kazempour Dizaji M; Gorji Bayani P; Fahimi F; Tabarsi P; Velayati AA · Iranian journal of pharmaceutical research : IJPR · 2016
    Randomized trial70 participantsDetoxification forMilk Thistle
  8. The hepatorenal protective effects of silymarin in cancer patients receiving chemotherapy: a randomized, placebo-controlled trial.
    Erfanian SS; Ansari H; Javanmard SH; Amini Z; Hajigholami A · BMC complementary medicine and therapies · 2024
    Randomized trial100 participantsDetoxification forMilk Thistle
  9. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  10. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  11. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle