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Milk Thistle Seed

4.7
★ ★ ★ ★ ★
(3767 ratings)
Milk Thistle 600 mg
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Score72
Concentrated liquid seed extract is relevant and focused, but missing active yield and short supply reduce value.
How scoring works
Capsule
Quantity:60 Liquid(s) • (20 servings)
Goals:
Detoxification

Score 72

Concentrated liquid seed extract is relevant and focused, but missing active yield and short supply reduce value.
How scoring works

Also available as

1 option
120 servings Milk Thistle 600 mg • 120 Liquid(s) • 40 servings $51.29 ($1.28 per serving)
$30.59($1.52 per serving)
iHerb
$ 30.59
Amazon
$ 30.59
Walmart
$ 30.59
Vitacost
$ 30.59
iHerb
$ 30.59
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Analysis

A 600 mg liquid milk thistle seed extract is directly relevant to antioxidant and liver-cell support. The focused ingredient list avoids the uncertainty of a multi-herb blend.

Seed sourcing and extract weight are disclosed, but no silymarin percentage or active amount is provided. Liquid delivery may aid solubility, though it cannot confirm how much active compound reaches the serving.

Only a short supply is provided, making sustained use comparatively costly. It suits people who value concentrated liquid delivery more than those optimizing value or verified potency.

Who is it for
  • Adults preferring liquid-filled capsules
  • Users wanting a focused seed extract
Best for
  • Concentrated liquid delivery
  • Simple milk-thistle supplementation

Pros

  • Milk thistle seed is identified
  • Concentrated liquid extract
  • Focused formula

Cons

  • No silymarin percentage
  • Short supply
  • High routine-use cost

Warnings

  • Milk thistle can cause digestive upset in some users; stop or reduce use if symptoms persist.
  • People allergic to ragweed-family plants may also react to milk thistle.
  • Milk thistle may affect blood sugar, so people using glucose-lowering medicine should discuss it with their clinician.

Nutrient quality

84 Highest impact

The preferred seed source and liquid delivery provide useful quality signals. The extract amount is substantial, but missing active-marker standardization leaves potency uncertain.

Ingredient transparency

78 High impact

The active ingredient has a stated amount without a hidden proprietary blend. Standardization or source details, daily-use directions, and non-active ingredients remain incomplete.

Customer satisfaction

71 High impact

The supplied average rating is very strong and is supported by large review count. No detailed feedback is available to assess repeated complaints or purpose-specific experiences.

Value for money

51 Moderate impact

Seed sourcing and liquid delivery support formula quality. The very high qualitative serving cost is difficult to justify without a verified active yield.

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Goals

Detoxification
Detoxification
Impact
High effect
A- Goal FitC+ Strength of SupportD- CoverageA Formula Quality
Milk Thistle · 600 mg

Milk thistle directly supports liver-cell protection and antioxidant defenses. The 600 mg liquid seed extract amount is relevant, but identifies the seed and liquid format but gives no active silymarin yield.

The focused formula provides depth in one liver-support pathway rather than broad metabolic clearance. Active silymarin yield and absorption quality remain the main uncertainties.

Study evidence
Milk Thistle Supportive 46 studies

Ingredients

IngredientAmount per serving
Calories
10 Calorie(s)
Total Carbohydrates
2 Gram(s)
Milk Thistle (Silybum marianum) seed extract
600 mg
Gluten Free Adults 18–50 Vegan Women Vegetarian
Report overview
Milk Thistle · 600 mg OverallScore24
C Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value

Liquid delivery may support better solubility than ordinary dry powder. Seed or fruit sourcing is appropriate, although the active-marker yield remains unclear. The very high serving cost lacks enough potency or delivery evidence to justify it.

View ingredientView products
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84 Performance

Milk Thistle

Nature's Answer
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the formula remains focused rather than broad.
85 Performance

Milk Thistle

Paradise
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the formula remains focused rather than broad.
79 Performance

Milk Thistle (Silymarin)

Mason Natural
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Its stronger combination of formulation quality and detoxification alignment makes it a more compelling focused option, although the formula remains focused rather than broad.
84 Budget

Milk Thistle

Kroeger Herb Products Co.
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. A lower serving cost improves routine value, although the formula remains focused rather than broad.
82 Budget

Super Milk Thistle

Nature's Way
Clearly disclosed silybin and silymarin give the milk-thistle component unusually strong active characterization. A lower serving cost improves routine value, although the added licorice may be unsuitable for some users.
87 Budget

Milk Thistle Extract 175 mg

Lake Avenue Nutrition
A clearly labeled total-silymarin extract provides focused and readily assessable milk-thistle activity. A lower serving cost improves routine value, although the formula remains focused rather than broad.
79 Value

Milk Thistle

Solgar
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
82 Value

Milk Thistle Phytosome 300 mg

Swanson
A named milk-thistle phytosome provides a better-characterized absorption strategy than a basic, unstandardized herb amount. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
80 Value

Milk Thistle

Kirkman
A silymarin-labeled milk-thistle extract provides more assessable active disclosure than a plain plant-mass claim. Favorable serving economics and a well-defined milk-thistle core create a useful quality-to-cost balance, although the formula remains focused rather than broad.
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury.
    Shahsavari K; Ardekani SS; Ardekani MRS; Esfahani MM; Kazemizadeh H; Jamialahmadi T; Iranshahi M; Khanavi M; Hasanpour M · BMC complementary medicine and therapies · 2025
    Meta-analysis3,545 participants55 studies pooledDetoxification forMilk Thistle
  2. Evaluation of Hepatoprotective Effect of Silymarin Among Under Treatment Tuberculosis Patients: A Randomized Clinical Trial.
    Marjani M; Baghaei P; Kazempour Dizaji M; Gorji Bayani P; Fahimi F; Tabarsi P; Velayati AA · Iranian journal of pharmaceutical research : IJPR · 2016
    Randomized trial70 participantsDetoxification forMilk Thistle
  3. Effect of 8 Weeks milk thistle powder (silymarin extract) supplementation on fatty liver disease in patients candidates for bariatric surgery.
    Mirhashemi SH; Hakakzadeh A; Yeganeh FE; Oshidari B; Rezaee SP · Metabolism open · 2022
    Observational studyDetoxification forMilk Thistle
  4. The effect of silymarin on liver enzymes in patients taking isotretinoin: A randomized clinical trial.
    Mirnezami M; Jafarimanesh H; Rezagholizamenjany M; Alimoradian A; Ranjbaran M · Dermatologic therapy · 2021
    Randomized trial74 participantsDetoxification forMilk Thistle
  5. Impact of Silymarin Supplements on Liver Enzyme Levels: A Systematic Review.
    Calderon Martinez E; Herrera D; Mogan S; Hameed Z; Jangda AA; Khan TJ; Mroke P; Sajid S; Shah YR; Baig I · Cureus · 2023
    Systematic review3,846 participants29 studies pooledDetoxification forMilk Thistle
  6. A randomized double-blind, placebo-controlled study of therapeutic effects of silymarin in β-thalassemia major patients receiving desferrioxamine.
    Moayedi B; Gharagozloo M; Esmaeil N; Maracy MR; Hoorfar H; Jalaeikar M · European journal of haematology · 2013
    Randomized trial97 participantsDetoxification forMilk Thistle
  7. The hepatorenal protective effects of silymarin in cancer patients receiving chemotherapy: a randomized, placebo-controlled trial.
    Erfanian SS; Ansari H; Javanmard SH; Amini Z; Hajigholami A · BMC complementary medicine and therapies · 2024
    Randomized trial100 participantsDetoxification forMilk Thistle
  8. A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury.
    Luangchosiri C; Thakkinstian A; Chitphuk S; Stitchantrakul W; Petraksa S; Sobhonslidsuk A · BMC complementary and alternative medicine · 2016
    Randomized trial55 participantsDetoxification forMilk Thistle
  9. A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis.
    El-Kamary SS; Shardell MD; Abdel-Hamid M; Ismail S; El-Ateek M; Metwally M; Mikhail N; Hashem M; Mousa A; Aboul-Fotouh A; El-Kassas M; Esmat G; Strickland GT · Phytomedicine : international journal of phytotherapy and phytopharmacology · 2009
    Randomized trial105 participantsDetoxification forMilk Thistle
  10. Effect of aerobic training with silymarin consumption on glycemic indices and liver enzymes in men with type 2 diabetes.
    Ghalandari K; Shabani M; Khajehlandi A; Mohammadi A · Archives of physiology and biochemistry · 2023
    Randomized trial60 participantsDetoxification forMilk Thistle
  11. Impact of silymarin-supplemented cookies on liver enzyme and inflammatory markers in non-alcoholic fatty liver disease patients.
    Jaffar HM; Bader Ul Ain H; Tufail T; Hanif A; Malik T · Food science & nutrition · 2024
    Clinical trial64 participantsDetoxification forMilk Thistle