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Glucosamine 500 mg Chondroitin 400 mg

21st Century
4.7
★ ★ ★ ★ ★
(286 ratings)
Sodium 125 mg
Potassium 205 mg
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Score64
A clearly dosed glucosamine and chondroitin tablet offers solid joint-focused value. Its 205 mg potassium amount is secondary and does not make it a heart-health product.
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Quantity:180 Tablet(s) • (60 servings)
Goals:

Score 64

A clearly dosed glucosamine and chondroitin tablet offers solid joint-focused value. Its 205 mg potassium amount is secondary and does not make it a heart-health product.
How scoring works
$35.99($0.59 per serving)
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Analysis

The serving combines 1,500 mg of glucosamine sulfate with 1,200 mg of chondroitin sulfate. Those transparent amounts give it a coherent joint-support role and are the main reason to consider the product.

Potassium is listed at 205 mg and sodium at 125 mg. The potassium contribution may help general intake, but it is partly offset by sodium and does not cover other important cardiovascular pathways.

Tablets may appeal to buyers who prefer fewer units than a multi-capsule serving, though size and swallowability are not supplied. Anticoagulant users should take the chondroitin interaction seriously, and people who must limit potassium need to count the listed amount.

Who is it for
  • Adults seeking joint-focused supplementation
  • People who prefer tablets
Best for
  • Glucosamine and chondroitin intake
  • A plainly dosed joint formula

Pros

  • Meaningful glucosamine sulfate amount
  • Meaningful chondroitin sulfate amount
  • Clearly lists potassium and sodium

Cons

  • Poor match for targeted heart support
  • Mineral contribution is modest
  • No broader joint-support cofactors are listed

Warnings

  • Chondroitin may increase bleeding risk with warfarin or other anticoagulants.
  • People with impaired kidney function or potassium-retaining medicines should account for the 205 mg potassium serving.

Nutrient quality

54 Moderate impact

The sodium source is not identified, so its form quality cannot be assessed confidently. The 125 mg sodium amount is too low for substantial sweat replacement.

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Ingredient transparency

74 High impact

Active amounts are listed clearly. No proprietary blend hides a key dose, but other ingredients and full directions are missing.

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Customer satisfaction

60 Moderate impact

The supplied average rating is generally strong and the rating volume provides an aggregate signal. No comment-level evidence is provided to assess recurring complaints or confirm how experience matches the intended purpose.

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Value for money

63 Moderate impact

The broader formula may offer utility, though sodium-specific value is only moderate. The main non-electrolyte actives are purposeful rather than obvious padding.

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Ingredients

IngredientAmount per serving
Calories
10 Calorie(s)
Total Carbohydrates
2 Gram(s)
Sodium
125 mg
Potassium
205 mg
Glucosamine Sulfate (Glucosamine Sulfate 2KCl)
1500 mg
Chondroitin Sulfate
1200 mg
Gluten Free Adults 18–50
Report overview
Sodium · 125 mg OverallScore65
D Active Ingredient Quality & BioavailabilityC+ Dose, Safety & Label TransparencyA+ Value

The label gives a sodium amount without naming its source, limiting purity assessment. 125 mg is below the target range for intense sweat replacement; supporting electrolytes are present, but their forms do not establish high bioavailability; no trace-mineral complex or buffering compound is disclosed. The disclosed carbohydrate or sugar load is low, and no artificial color is listed; the low serving cost provides strong value.

Potassium · 205 mg OverallScore57
D+ Active Ingredient Quality & BioavailabilityC Dose, Safety & Label TransparencyC Value

The potassium contribution is moderate and likely comes from potassium chloride used in the glucosamine complex. Elemental intake is reasonably inferable, though the label does not show both compound weight and potassium yield. Low serving cost makes the contribution useful, but the formula is built mainly for joint support.

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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Oral potassium supplementation for management of essential hypertension: A meta-analysis of randomized controlled trials.
    Poorolajal J; Zeraati F; Soltanian AR; Sheikh V; Hooshmand E; Maleki A · PloS one · 2017
    Meta-analysis1,213 participants23 studies pooledHeart Health forPotassium
  2. Effect of Potassium Supplementation on Endothelial Function: A Systematic Review and Meta-Analysis of Intervention Studies.
    D'Elia L; Cappuccio FP; Masulli M; La Fata E; Rendina D; Galletti F · Nutrients · 2023
    Meta-analysis332 participants5 studies pooledHeart Health forPotassium
  3. Potassium intake, stroke, and cardiovascular disease a meta-analysis of prospective studies.
    D'Elia L; Barba G; Cappuccio FP; Strazzullo P · Journal of the American College of Cardiology · 2011
    Meta-analysis247,510 participants11 studies pooledHeart Health forPotassium
  4. Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length.
    Behers BJ; Behers BM; Stephenson-Moe CA; Vargas IA; Meng Z; Thompson AJ; Melchor J; Wojtas CN; Rosario MA; Baker JF; Deevers AC; Mouratidis RW; Sweeney MJ · Nutrients · 2024
    Meta-analysisHeart Health forPotassium
  5. Potassium intake and risk of stroke in women with hypertension and nonhypertension in the Women's Health Initiative.
    Seth A; Mossavar-Rahmani Y; Kamensky V; Silver B; Lakshminarayan K; Prentice R; Van Horn L; Wassertheil-Smoller S · Stroke · 2015
    Cohort study90,137 participantsHeart Health forPotassium
  6. Effect of high potassium diet on endothelial function.
    Blanch N; Clifton PM; Petersen KS; Willoughby SR; Keogh JB · Nutrition, metabolism, and cardiovascular diseases : NMCD · 2015
    Randomized trial35 participantsHeart Health forPotassium
  7. Associations between sodium, potassium, and blood pressure: results from the Hispanic Community Health Study/Study of Latinos, a prospective cohort study.
    Swift SL; Sotres-Alvarez D; Raij L; Wassertheil-Smoller S; Schneiderman N; Llabre M; Zeki Al Hazzouri A; Rundek T; Van Horn L; Daviglus M; Castaneda S; Youngblood M; Mossavar-Rahmani Y; Elfassy T · The American journal of clinical nutrition · 2024
    Cohort study11,429 participantsHeart Health forPotassium
  8. Serum potassium levels provide prognostic information in symptomatic heart failure beyond traditional clinical variables.
    Toledo CC; Vellosa Schwartzmann P; Miguel Silva L; da Silva Ferreira G; Bianchini Cardoso F; Citelli Ribeiro V; Paim LR; Antunes-Correa LM; Carvalho Sposito A; Matos Souza JR; Modolo R; Nadruz W; Fernandes de Carvalho LS; Coelho-Filho OR · ESC heart failure · 2021
    Cohort study178 participantsHeart Health forPotassium
  9. Long-Term Potassium Monitoring and Dynamics in Heart Failure and Risk of Mortality.
    Núñez J; Bayés-Genís A; Zannad F; Rossignol P; Núñez E; Bodí V; Miñana G; Santas E; Chorro FJ; Mollar A; Carratalá A; Navarro J; Górriz JL; Lupón J; Husser O; Metra M; Sanchis J · Circulation · 2019
    Cohort study2,164 participantsHeart Health forPotassium
  10. Finerenone, Serum Potassium, and Clinical Outcomes in Heart Failure With Mildly Reduced or Preserved Ejection Fraction.
    Vardeny O; Vaduganathan M; Claggett BL; Desai AS; Jhund PS; Lam CSP; Senni M; Shah SJ; Voors AA; Zannad F; Pitt B; Matsumoto S; Merkely B; Zieroth S; Yilmaz MB; Lay-Flurrie J; Viswanathan P; Horvat-Broecker A; Scalise A; McMurray JJV; Solomon SD · JAMA cardiology · 2025
    Randomized trial6,001 participantsHeart Health forPotassium