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Papaya Supreme

Swanson Premium Brand
4.6
★ ★ ★ ★ ★
(231 ratings)
Papain 100 mg
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Score83
A two-tablet serving built around 100 mg of papaya-derived papain, with a focused single-active formula. Useful breadth is offset because proteolytic activity units are not supplied.
How scoring works
Quantity:300 Tablet(s) • (150 servings)
Goals:
Digestive Health

Score 83

A two-tablet serving built around 100 mg of papaya-derived papain, with a focused single-active formula. Useful breadth is offset because proteolytic activity units are not supplied.
How scoring works
$26.33($0.17 per serving)
Amazon
$ 26.33
iHerb
$ 0.00
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Analysis

The two-tablet serving supplies 100 mg of papaya-derived papain as its papain component. It also includes a focused single-active formula.

The narrow formula makes it easy to identify the intended protein-digestion support and avoids active-ingredient padding. Milligram weight alone does not show how much proteolytic work the enzyme can perform.

The key limitation is that proteolytic activity units are not supplied. The product is most suitable for adults who want a simple, higher-weight papain product, with expectations kept to routine meal support rather than a precisely verified potency.

Who is it for
  • adults who want a simple, higher-weight papain product
  • people seeking digestive support with a clearly listed papain amount
Best for
  • meal-time digestive enzyme support
  • focused protein digestion

Pros

  • Clearly lists 100 mg of papaya-derived papain
  • Single-active formula is easy to evaluate
  • Two-tablet serving offers convenient use

Cons

  • Proteolytic activity units are not supplied
  • Enzyme weight does not establish digestive activity
  • Label gives limited evidence for batch-to-batch potency

Warnings

  • Papain may trigger reactions in people with papaya or latex allergy.

Nutrient quality

88 Highest impact

Papaya is named as the source, but purification and activity units are missing. The high papain amount provides substantial focused digestive support, and the single enzyme has a clear protein-digestion purpose.

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Ingredient transparency

81 Highest impact

Every listed active has a specific amount and no proprietary blend obscures key enzyme doses. Complete intake directions and inactive ingredients are not supplied, leaving part of the label unverified.

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Customer satisfaction

67 High impact

The supplied aggregate satisfaction level is strong. The moderate feedback volume offers a useful but not definitive aggregate.

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Value for money

95 Highest impact

The substantial disclosed amount strongly supports the modest cost. The serving offers strong value, and the product compares favorably among simple high-dose papain options.

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Goals

Digestive Health
Digestive Health
Impact
High effect
B- Goal FitB- Strength of SupportD- CoverageA+ Formula Quality
Papain · 100 mg

Papain offers direct support for protein breakdown and may help with meal-related digestive comfort. The 100 mg amount is disclosed, but enzyme activity units are not provided.

The simple formula is coherent and easy to understand. Its benefit is narrow because it does not address regularity, the microbiome, or gut-barrier support.

Study evidence
Papain Adverse 2 studies

Ingredients

IngredientAmount per serving
Papain (Papaya)
 100 mg
Adults 18–50
Report overview
Papain (Papaya) · 100 mg OverallScore78
D+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyB+ Value

The individually listed papain amount reaches the higher-dose range. Biological activity units and purified Carica papaya extract details are missing, so true enzymatic potency remains uncertain. Serving cost is favorable for the disclosed amount.

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84 Performance

Papain Papaya Enzyme 100 mg

Swanson Premium Brand
<p>A focused single-ingredient formula supplies a substantial papain amount. Compared with Papaya Supreme, the higher papain amount and simple ingredient list provides a stronger ingredient-based fit for digestive enzyme support, although the papain source and activity units are not disclosed.</p>
83 Performance

Natural Tropical Papaya

Country Life
<p>Papaya-sourced papain and papaya are balanced with clearly sourced fungal protease and alpha-amylase. Compared with Papaya Supreme, the balanced enzyme amounts and clear biological sources provides a stronger ingredient-based fit for digestive enzyme support, although activity units are absent.</p>
73 Performance

Chewable Nutri-Zyme Natural Peppermint

Natures Plus
<p>Papaya-sourced papain and pineapple-derived bromelain are paired with amylase and lipase at meaningful disclosed weights. Compared with Papaya Supreme, the substantial papain and bromelain amounts plus broader enzyme coverage provides a stronger ingredient-based fit for digestive enzyme support, although activity units are missing and papain or bromelain may not suit everyone.</p>
75 Budget

Chewable Papaya Enzymes

NOW
<p>Papain, papaya fruit powder, pineapple-derived bromelain, protease, amylase, lipase, and cellulase provide broad plant-enzyme coverage. Its lower cost per serving than Papaya Supreme makes it a more economical choice, although activity units and the papain source are not disclosed.</p>
83 Budget

Chewable Original Papaya Enzyme

American Health
<p>A practical papain amount is paired with amylase and protease in a simple chewable. Its lower cost per serving than Papaya Supreme makes it a more economical choice, although enzyme activity units are missing.</p>
74 Budget

Digestive Enzymes

Mason Natural
<p>Pancreatin, diastase, papain, pepsin, betaine hydrochloride, lipase, and bromelain provide broad digestive coverage. Its lower cost per serving than Papaya Supreme makes it a more economical choice, although activity units are missing and the acidophilus amount is not meaningful as disclosed.</p>
83 Value

Chewable Papaya Enzyme with Chlorophyll

American Health
<p>Papaya-sourced papain is paired with clearly sourced fungal protease and alpha-amylase. Compared with Papaya Supreme, its lower serving cost and the clearly identified enzyme sources support a more favorable quality-to-cost balance, although the chlorophyll adds little and activity units are missing.</p>
84 Value

Digestive Enzymes

Swanson
<p>Pancreatin, ox bile, barley-malt diastase, papain, cellulase, bromelain, and betaine hydrochloride cover several stages of digestion. Compared with Papaya Supreme, its lower serving cost and the broad enzyme and bile profile support a more favorable quality-to-cost balance, although activity units are incomplete and animal-derived ingredients narrow suitability.</p>
76 Value

Full Spectrum Optimum Enzymes

Bluebonnet
<p>Papain, bromelain, amylase, protease, glucoamylase, lipase, and cellulase cover several food components. Compared with Papaya Supreme, its ingredient advantages and the broad plant-enzyme combination support a more favorable quality-to-cost balance, although the papain amount is modest and activity units are absent.</p>
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Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The incidence and clinical implications of hypersensitivity to papain in an allergic population, confirmed by blinded oral challenge.
    Mansfield LE; Ting S; Haverly RW; Yoo TJ · Annals of allergy · 1985
    Clinical trial500 participantsDigestive Health forPapain
  2. Papaya preparation (Caricol®) in digestive disorders
    Muss C, Mosgoeller W, Endler T · Neuro Endocrinology Letters · 2013
    Randomized trial76 participantsDigestive Health forPapain