Systemic Enzyme Complex

Systemic Enzyme Complex

Pure Encapsulations4.6 (17 ratings)
Format:Capsule Quantity: 180 Capsule(s) · 60 servings
Goals
$81.00 $1.35 per serving
Pure Formulas$81.00

About this product

The formula combines pancreatin, several proteases, bromelain, papain, trypsin, chymotrypsin, rutin, and 250 mg of Boswellia extract. Multiple enzyme sources provide broad protein-digestion potential, while Boswellia gives the blend a separate botanical focus.

The ingredient breadth may support several related pathways, but a longer formula also makes dose quality and overlap more important. Suitability depends on wanting the complete combination rather than one collection ingredient alone.

Enzymes are listed by weight rather than activity units, and the Boswellia extract lacks boswellic-acid percentage, AKBA yield, and absorption support. The 60-serving capsule supply should therefore be judged by active-form clarity and suitability, not just the listed botanical weight.

Who is it for
  • Adults intentionally seeking a broad enzyme blend
  • People who prefer supplements in capsule form
  • Users who want several related ingredients in one serving
Best for
  • Multi-enzyme digestive support when taken with meals
  • Combining several related support pathways
  • A routine with 60 servings per container

Pros

  • Includes several complementary proteolytic enzymes
  • Papain and bromelain amounts are disclosed
  • Boswellia extract is measured rather than hidden in a blend

Cons

  • Enzyme activity units are not provided.
  • Boswellia active-marker percentages are absent.
  • The broad formula is expensive for dedicated Boswellia or papain use.
  • Animal-derived enzymes limit dietary suitability.

Warnings

  • Porcine pancreatin and trypsin plus bovine chymotrypsin make the formula unsuitable for people avoiding pig or cattle-derived ingredients.
  • Papain and bromelain warrant caution for people with papaya or pineapple sensitivity.
  • Proteolytic enzymes and Boswellia may add to bleeding tendency with anticoagulant or antiplatelet medicines.

Product analysis

68 out of 100
Systemic Enzyme Complex offers broad ingredient coverage with meaningful formulation trade-offs. Enzymes are listed by weight rather than activity units, and the Boswellia extract lacks boswellic-acid percentage, AKBA yield, and absorption support.

AI assessment of the formula, label and price. How scoring works

Nutrient quality74

Several proteolytic enzymes and a practical Boswellia amount provide coherent formula depth. Missing enzyme activity units and incomplete botanical standardization keep dose quality uncertain.

Ingredient transparency80

All active weights are disclosed without a hidden blend. Missing activity units, directions, and non-active ingredients prevent a complete label assessment.

Customer satisfaction61

The supplied average rating is strong and the rating volume is limited. No specific experience details were provided to judge repeated complaints or purpose alignment.

Value for money51

A broad and purposeful enzyme profile provides some justification for the cost. Premium pricing is hard to support when actual enzyme potency is not disclosed.

Format
Capsule
Container
180 Capsule(s)
Per serving
$1.35
Customer rating
4.6 · 17 ratings
Report analysis

Goals

Digestive Health
Digestive Health
Impact
Moderate effect
C+ Ingredient FitF PathwaysB EvidenceA+ Formulation Logic
Papain · 120 mgBromelain · 120 mgBoswellia · 250 mg
Study evidence
Boswellia Supportive 9 studies
Bromelain Supportive 2 studies
Papain Adverse 2 studies

Ingredients

IngredientAmount per servingScore
Pancreatin (Porcine)
 176 mg
Protease 6
120 mg
Serrazimes (Protease)
 17 mg
Bromelain (Pineapple)
 120 mg
Papain (Papaya)
 120 mg 84
Rutin
100 mg
Trypsin (Porcine)
 75 mg
Chymotrypsin (Bovine)
 3 mg
Indian Frankincense (Boswellia serrata) extract (Boswellic Acids)
 250 mg 100
Gluten Free Adults 18–50
Report overview
Papain (Papaya) · 120 mg OverallScore84
A+ Composition And Label DisclosureA+ Composition And Label DisclosureF Commercial Price And Usability
Systemic Enzyme Complex lists 120 mg of papain and an 800-unit activity declaration per labeled serving. Its specific form is not identified. The serving cost is high; the activity figure describes enzyme activity separately from ingredient mass.
How this ingredient is rated

Composition and Label Disclosure100

A numerical papain activity declaration is listed separately from ingredient mass.
Declared Papain Activity Units
The label declares 800 units of papain activity.

Composition and Label Disclosure100

The label gives a papain amount, though its specific source form is unknown.
Individual Preparation Amount Disclosure
It lists 120 mg of papain as the individual amount.

Commercial Price and Usability20

The whole-product cost per labeled serving is high.
Commercial Price per Labeled Serving
The cost for a labeled serving is high.
View ingredientView products
Boswellia (Boswellic Acids) · 250 mg OverallScore100
A+ Composition And Label DisclosureA+ Composition And Label Disclosure
Systemic Enzyme Complex lists 250 mg of Boswellia serrata gum resin extract and records 70% boswellic acids. The serving amount and associated marker percentage are both stated in the saved details. No Boswellia-specific price comparison is provided.
How this ingredient is rated

Composition and Label Disclosure100

The saved details identify gum resin extract and record a 70% boswellic-acid marker level.
Marker and Preparation Disclosure
The extract is listed with 70% boswellic acids.

Composition and Label Disclosure100

The serving amount is paired with an associated boswellic-acid percentage.
Boswellia Amount and Marker Disclosure
The saved details state 250 mg of extract with 70% boswellic acids.

Commercial Price and Usability

No Boswellia-specific price comparison is provided here.
View ingredientView products
Loading alternative details
84 Performance

Boswellia Extract 500 mg

California Gold Nutrition

Boswellia Extract 500 mg offers a stronger ingredient-led alternative to Systemic Enzyme Complex through 500 mg of Boswellia extract plus turmeric extract and powder. The well-aligned botanical combination improves anti-inflammatory support, but it does not replace the original papain and protease blend.

85 Performance

Digestive Enzymes

Swanson

Digestive Enzymes offers a stronger ingredient-led alternative to Systemic Enzyme Complex through pancreatin, ox bile, papain, cellulase, bromelain, and betaine hydrochloride. The broader digestive-enzyme coverage is useful, although activity units are not supplied and Boswellia is absent.

83 Performance

Boswellia AKBA

Pure Encapsulations

Boswellia AKBA offers a stronger ingredient-led alternative to Systemic Enzyme Complex through 100 mg of 5-LOXIN Boswellia extract. The named extract improves ingredient definition, though the product addresses Boswellia rather than the full original blend.

83 Budget

Chewable Original Papaya Enzyme

American Health

Chewable Original Papaya Enzyme lowers serving cost while providing 45 mg of papain with amylase and protease. The inexpensive chewable retains digestive-enzyme activity, but activity units are missing and Boswellia is omitted.

81 Budget

Boswellia Extract 600 mg

Herbal Secrets

Boswellia Extract 600 mg lowers serving cost while providing 600 mg of Boswellia gum-resin extract identified by boswellic acids. The focused formula is easy to assess, but it supplies Boswellia alone.

84 Budget

Papain Papaya Enzyme 100 mg

Swanson Premium Brand

Papain Papaya Enzyme 100 mg lowers serving cost while providing 100 mg of papain in a single-active formula. The label is simple and economical, though it does not reproduce the original broad enzyme blend or Boswellia.

81 Value

Boswellia Extract 500 mg

NOW

Boswellia Extract 500 mg balances formula quality and cost with 500 mg of Boswellia extract identified by boswellic and organic acids. The concise formula offers strong quality and value evidence, but it covers only one of the original collections.

83 Value

Chewable Papaya Enzyme with Chlorophyll

American Health

Chewable Papaya Enzyme with Chlorophyll balances formula quality and cost with papain with protease, amylase, papaya, and chlorophyll. The focused digestive profile has favorable value, but its enzyme amounts are modest and it omits Boswellia.

79 Value

Boswellia Serrata Extract 125 mg

Swanson Ultra

Boswellia Serrata Extract 125 mg balances formula quality and cost with 125 mg of 5-LOXIN Boswellia identified by AKBA. The standardized botanical gives strong ingredient clarity and value, while the enzyme side of the original is not covered.

Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The incidence and clinical implications of hypersensitivity to papain in an allergic population, confirmed by blinded oral challenge.
    Mansfield LE; Ting S; Haverly RW; Yoo TJ · Annals of allergy · 1985
    Clinical trial500 participantsDigestive Health forPapain
  2. Positive Effects of a Lecithin-Based Delivery Form of Boswellia serrata Extract in Acute Diarrhea of Adult Subjects.
    Giacosa A; Riva A; Petrangolini G; Allegrini P; Fazia T; Bernardinelli L; Peroni G; Rondanelli M · Nutrients · 2022
    Randomized trial49 participantsDigestive Health forBoswellia
  3. Antioxidant Supplements and Gastrointestinal Diseases: A Critical Appraisal.
    Khan I; Samson SE; Grover AK · Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2018
    Narrative reviewDigestive Health forBoswellia
  4. Supplementation with a lecithin-based delivery form of Boswellia serrata extract (Casperome®) controls symptoms of mild irritable bowel syndrome.
    Belcaro G; Gizzi G; Pellegrini L; Corsi M; Dugall M; Cacchio M; Feragalli B; Togni S; Riva A; Eggenhoffner R; Giacomelli L · European review for medical and pharmacological sciences · 2018
    Non-randomized trial71 participantsDigestive Health forBoswellia
  5. Interventions for treating collagenous colitis.
    Kafil TS; Nguyen TM; Patton PH; MacDonald JK; Chande N; McDonald JW · The Cochrane database of systematic reviews · 2018
    Systematic review31 participants1 studies pooledDigestive Health forBoswellia
  6. Interventions for treating collagenous colitis.
    Chande N; McDonald JW; MacDonald JK · The Cochrane database of systematic reviews · 2007
    Systematic review31 participants1 studies pooledDigestive Health forBoswellia
  7. The role of enzyme supplementation in digestive disorders.
    Roxas M · Alternative medicine review : a journal of clinical therapeutic · 2009
    Narrative reviewDigestive Health forBromelain
  8. Effects of bromelain supplementation on disease activity and quality of life in patients with ulcerative colitis: a randomized, triple-blind, placebo-controlled study.
    Delgarm P; Mokhtare M; Ebrahimi Daryani N; Abolghasemi J; Rahideh ST · Scientific reports · 2025
    Randomized trial70 participantsDigestive Health forBromelain
  9. Papaya preparation (Caricol®) in digestive disorders
    Muss C, Mosgoeller W, Endler T · Neuro Endocrinology Letters · 2013
    Randomized trial76 participantsDigestive Health forPapain