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Conjugated Linoleic Acid

notesDescription

Conjugated Linoleic Acid (CLA) is a naturally occurring trans fatty acid, primarily found in the meat and dairy products of ruminant animals. It is a derivative of linoleic acid, an omega-6 fatty acid, but with a unique structure involving conjugated double bonds. This structural difference is believed to contribute to its distinct biological activities compared to other fatty acids. CLA gained significant attention for its potential health benefits, particularly in the areas of body composition and metabolic health. Research has explored its role in reducing body fat, increasing lean muscle mass, and modulating lipid metabolism. It is also studied for its anti-inflammatory and antioxidant properties, suggesting broader health implications beyond weight management. Available as a dietary supplement, CLA typically consists of a mixture of different CLA isomers, with cis-9, trans-11 (c9,t11) and trans-10, cis-12 (t10,c12) being the most common and biologically active. The specific effects of CLA can vary depending on the isomer composition and the dosage used in studies.

ecoSources
BeefLambDairy products (milk, cheese, yogurt)Eggs (to a lesser extent, depending on animal feed)
Cheapest Conjugated Linoleic Acid Supplements
Discover the most affordable Conjugated Linoleic Acid supplements to support your weight loss, metabolism boost, and immunity goals.
Best Conjugated Linoleic Acid supplements
Discover the best Conjugated Linoleic Acid fatty acid supplements for Weight Loss, Metabolism Boost, and Immunity.
Value Conjugated Linoleic Acid Supplements
Compare top-rated Conjugated Linoleic Acid (CLA) supplements to find the best value for your weight loss, metabolism boost, and immunity goals.
check_circleOptimal Dosage
Minimum1000 mg
Maximum3000 mg
report_problemSafety & Toxicity
track_changesGoals
Immunity
health_and_safetyImmunity
Impact
Limited evidence
Typical dose:3.2–6.4 grams
While some research suggests CLA can influence inflammatory markers in specific contexts, it lacks robust clinical evidence for general immune support or acute infection response. Its effects are not consistently demonstrated and are considered speculative for this purpose.
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Metabolism Boost
local_fire_departmentMetabolism Boost
Impact
Limited evidence
Typical dose:3.2–6.4 grams
Human clinical trials on CLA have produced mixed results, with any observed effects on fat mass or metabolic rate being very modest and not reliably reproducible. Its classification should reflect the low probability of a meaningful outcome for the average user.
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Weight Loss
trending_downWeight Loss
Impact
Limited evidence
Typical dose:3.2–6.4 grams
While animal studies show promise, human trials on CLA have produced mixed and often clinically insignificant results for fat loss. Any potential effects on inhibiting fat storage or increasing fat burning are typically very small and not reliably observed across the population.
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sync_altInteractions

add_circle_outlinePositive Interactions

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Omega-3
May synergistically support anti-inflammatory responses and overall metabolic health, as both are beneficial fatty acids.
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Omega-6
As a derivative of linoleic acid, CLA's metabolism is intrinsically linked with other omega-6 fatty acids, potentially contributing to a balanced fatty acid profile.
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L-Carnitine
May enhance fat metabolism and energy production, potentially complementing CLA's role in body composition by facilitating fatty acid transport.
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Chromium
May support healthy glucose and lipid metabolism, potentially complementing CLA's effects on body composition and mitigating potential impacts on insulin sensitivity.

remove_circle_outlineNegative Interactions

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Iron
Some animal studies suggest CLA might influence iron status; monitoring may be advised, especially with high doses.
inventory_2Recommended products
85 Best CLA 1250

CLA 1250

MRM
4.4
★★★★★
(620 ratings)
Conjugated Linoleic Acid: 1250 mg
A high-dose CLA supplement sourced from safflower oil, offering excellent value with a very competitive price per serving.
Buy for $16.49(from Pure Formulas)
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80 Best CLA

CLA

Natural Factors
4.7
★★★★★
(329 ratings)
Conjugated Linoleic Acid: 2000 mg
The largest and most cost-effective option for Natural Factors' high-dose 1620mg Tonalin CLA, with strong ingredient transparency.
Buy for $39.17(from iHerb)
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88 Best Tonalin CLA

Tonalin CLA

Natrol
4.3
★★★★★
(1776 ratings)
Conjugated Linoleic Acid: 1200 mg
A Tonalin CLA supplement delivering 1200mg per serving, offering great value and supported by extensive customer satisfaction.
Buy for $20.06(from iHerb)
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90 Best Tonalin 1300 mg CLA

Tonalin 1300 mg CLA

Solgar
4.6
★★★★★
(1859 ratings)
Conjugated Linoleic Acid: 1300 mg
A high-quality Solgar supplement offering 1014mg of actual Tonalin CLA, with excellent transparency, good value, and extensive positive customer feedback.
Buy for $18.69(from Vitacost)
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85 Best Tonalin CLA 1200 mg

Tonalin CLA 1200 mg

Natrol
4.3
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(1776 ratings)
Conjugated Linoleic Acid: 1200 mg
A Natrol Tonalin CLA supplement providing 936mg of actual CLA, offering good transparency and a competitive price, with strong customer satisfaction.
Buy for $14.99(from iHerb)
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65 Budget Garcinia Cambogia with Apple Cider Vinegar

Garcinia Cambogia with Apple Cider Vinegar

Angry Supplements
4.1
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Conjugated Linoleic Acid: 200 mg
This tablet offers a multi-ingredient blend with Garcinia Cambogia, Apple Cider Vinegar, and Chromium, designed for general metabolic and weight management support.
Buy for $14.99(from Walmart)
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62 Budget Garcinia Cambogia with Melatonin

Garcinia Cambogia with Melatonin

Angry Supplements
2.8
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Conjugated Linoleic Acid: 50 mg
This product combines multiple ingredients for broad support across sleep, mood, and weight management, but the individual dosages for many of these compounds are quite low.
Buy for $14.99(from Walmart)
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60 Best CLA

CLA

Designs for Health
4.8
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Conjugated Linoleic Acid: 1000 mg
A CLA supplement featuring branded Clarinolâ„¢ at 1000mg per serving, but with a high price point and very little customer feedback.
Buy for $45.49(from Pure Formulas)
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88 Budget 7-KETO LeanGels 100 mg

7-KETO LeanGels 100 mg

NOW
4.5
★★★★★
(952 ratings)
Conjugated Linoleic Acid: 400 mg
This NOW 7-KETO LeanGels product in a 120-count size delivers a blend of metabolism-aiding ingredients like 7-KETO and CLA, alongside Green Tea, Acetyl-L-Carnitine, and Rhodiola that may support energy and cognitive function, all at an excellent per-serving price.
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75 Best CLA

CLA

Natural Factors
4.7
★★★★★
(658 ratings)
Conjugated Linoleic Acid: 2000 mg
A high-dose CLA supplement providing 1620mg of Tonalin CLA, offering excellent ingredient transparency but at a higher price per serving.
Buy for $16.77(from iHerb)
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78 Best CLA

CLA

Natural Factors
4.7
★★★★★
(329 ratings)
Conjugated Linoleic Acid: 2000 mg
A high-dose Tonalin CLA supplement (1620mg actual CLA) from Natural Factors, providing improved value over smaller sizes.
Buy for $21.09(from Vitacost)
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55 Best CLA 1000 mg

CLA 1000 mg

Pure Encapsulations
4.5
★★★★★
(11 ratings)
Conjugated Linoleic Acid: 1000 mg
A Tonalin CLA supplement at 1000mg with added Vitamin E, notable for its very high price and minimal customer reviews.
Buy for $132(from Pure Formulas)
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83 Value CLA95

CLA95

ALLMAX
4.5
★★★★★
(545 ratings)
Conjugated Linoleic Acid: 1000 mg
An ALLMAX CLA supplement providing 950mg of actual CLA with excellent transparency and a very competitive price per serving.
Buy for $24.99(from Vitacost)
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80 Budget LEANMODE

LEANMODE

Evlution Nutrition
4.3
★★★★★
(21528 ratings)
Conjugated Linoleic Acid: 500 mg
This product combines several popular ingredients like green tea, green coffee, and acetyl-L-carnitine into a single supplement, aiming to support metabolism, energy, and overall body composition goals. It provides a broad-spectrum approach for those seeking integrated metabolic assistance.
Buy for $19.7(from iHerb)
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65 Best CLA Lean

CLA Lean

Irwin Naturals
4.3
★★★★★
(203 ratings)
Conjugated Linoleic Acid: 1700 mg
A high-dose CLA (1700mg) supplement featuring a blend of beneficial oils and BioPerine, but at a very high price point per serving.
Buy for $20.99(from Pure Formulas)
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92 Value CLA 1000 mg

CLA 1000 mg

California Gold Nutrition
4.6
★★★★★
(2929 ratings)
Conjugated Linoleic Acid: 1000 mg
A highly-rated CLA supplement providing 1000mg from safflower oil, offering exceptional value and customer satisfaction at a very low price.
Buy for $18.87(from iHerb)
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analyticsProduct stats
sellPrice per product
Average$24.78
Median$20.06
restaurantPrice per serving
Average$0.49
Median$0.45
sciencePrice per 1000 mg
Average$0.65
Median$0.33
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bar_chartPrice per serving distribution
bar_chartPrice per 1000 mg
Reference amount: 1000 mg
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