Prostate Defense 320 mg Saw Palmetto

Prostate Defense 320 mg Saw Palmetto

Applied Nutrition4.5 (203 ratings)
Format:Softgel Quantity: 50 Liquid(s) · 25 servings
Goals
$14.99 $0.59 per serving

Product analysis

39 out of 100

Prostate Defense 320 mg Saw Palmetto combines botanicals and nutrients with conditional support for hair and normal immune functions. Several undisclosed herb amounts and preparations make the complete mixture harder to judge.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality20

Most botanical and oil preparations are not specified. The mixture’s less clearly identified portion adds uncertainty about ingredient quality.

Ingredient Transparency27

Several ingredient amounts and preparation details are omitted. Missing botanical composition details also make comparisons with similar formulas difficult.

Value For Money36

The serving is relatively costly for its lycopene contribution. Uncertain value from the other assessed ingredients limits a firm judgment about the combined purchase.

Customer Satisfaction69

Customer ratings are generally favorable. The relatively modest review pool gives a narrower picture than a large body of feedback.

Product Focus67

The clearest support concerns zinc-related nutritional gaps, with more limited hair-related support from saw palmetto. The mixed formula does not establish the same benefit across all of its ingredients.

Format
Softgel
Container
50 Liquid(s)
Per serving
$0.59
Customer rating
4.5 · 203 ratings
Report analysis

Goals

Hair Health
Impact
High effect
C- Ingredient FitC- PathwaysA EvidenceA+ Formulation Logic
Zinc · 10 mg
Study evidence
Selenium Disputed 7 studies
Zinc Supportive 22 studies
Skin Health
Impact
High effect
C- Ingredient FitC PathwaysA- EvidenceA+ Formulation Logic
Zinc · 10 mgSelenium · 200 mcgLycopene · 10 mg
Study evidence
Lycopene Supportive 20 studies
Selenium Supportive 22 studies
Zinc Supportive 66 studies
Immunity
Impact
High effect
D Ingredient FitD+ PathwaysA+ EvidenceA+ Formulation Logic
Zinc · 10 mgSelenium · 200 mcg
Study evidence
Selenium Mixed 37 studies
Zinc Supportive 73 studies

Ingredients

IngredientAmount per servingScore
Zinc (Zinc Citrate)
10 mg
Selenium (Selenium Amino Acid Chelate)
200 mcg 67
Fish Oil
320 mg 6
Saw Palmetto extract (Fatty Acids)
320 mg 80
Pygeum extract (Sitosterols)
100 mg
Beta Sitosterol
60 mg
Pumpkin seed Oil
50 mg
Lycopene
10 mg 77
Urinary Tract Complex
50 mg
Juniper berry powder
0 NP
Uva-Ursi powder
0 NP
Buchu powder
0 NP
Cranberry (Vaccinium macrocarpon) juice powder
0 NP
Adults 18–50
Report overview
A+ Composition And Label DisclosureC Composition And Label Disclosure
A serving provides 320 mg of saw palmetto fruit extract; a value comparison for saw palmetto is unavailable. The preparation lists 85% fatty acids.
How this ingredient is rated

Composition and Label Disclosure100

The preparation lists 85% fatty acids.
Marker and Preparation Disclosure
The preparation lists 85% fatty acids.

Composition and Label Disclosure60

The serving lists 320 mg of saw palmetto fruit extract. The preparation lists 85% fatty acids.
Amount and Label Disclosure
The serving lists 320 mg of saw palmetto fruit extract. The preparation lists 85% fatty acids.

Commercial Price and Usability

A value comparison for saw palmetto is unavailable.
Lycopene · 10 mg OverallScore77
A+ Composition And Label DisclosureF Commercial Price And Usability
The serving provides 10 mg of lycopene, with a high whole-product cost for the amount supplied. The lycopene source is unknown.
How this ingredient is rated

Composition and Label Disclosure

The lycopene source is unknown, so its form cannot be compared.

Composition and Label Disclosure100

The label states 10 mg of active lycopene per serving.
Declared Active Lycopene Amount
The stated serving contains 10 mg of active lycopene.

Commercial Price and Usability30

The whole-product cost for an equivalent amount of lycopene is high.
Whole-Product Cost per 10 mg Declared Active Lycopene
The whole-product cost per equivalent amount of lycopene is high.
D+ Active Ingredient Quality & BioavailabilityA+ Dose, Safety & Label TransparencyF Value
Each serving provides 200 mcg of selenium, at a fairly high cost relative to the amount. The amount is clearly stated. The label names a selenium amino acid complex, but does not specify the compound.
How this ingredient is rated

Active Ingredient Quality & Bioavailability53

The label names a selenium amino acid complex, but does not specify the compound. Its exact compound is not specified.
Selenium Chemical Form
The label names a selenium amino acid complex, but does not specify the compound.
Form Transparency & Isomer Specificity
The specific compound in the amino acid form is not named.

Dose, Safety & Label Transparency100

200 mcg is an amount used in research on antioxidant and thyroid support. It is below the stated adult upper intake limit.
Dosage Efficacy Sweet Spot
200 mcg is an amount used in research on antioxidant and thyroid support.
Safety Margin & UL Adherence
200 mcg is below the stated adult upper intake limit, leaving room for selenium from food.

Value30

The cost is fairly high relative to the selenium amount.
Price per 200 mcg Serving
The cost is fairly high relative to the selenium amount.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The Safety and Efficacy of a Proprietary Bioactive Fatty Acids Extract From Saw Palmetto (Serenoa repens) for Promoting Hair Growth and Reducing Hair Loss in Adults With Self-Perceived Thinning Hair: 90-Day Results.
    Ablon G · Journal of cosmetic dermatology · 2025
    Randomized trial60 participantsHair Health forSaw Palmetto
  2. Effects of dietary supplements on androgenetic alopecia: a systematic review and network meta-analysis.
    Zhou L; Zhu W; Chen Y · Frontiers in nutrition · 2026
    Meta-analysis1,658 participants19 studies pooledHair Health forSaw Palmetto
  3. The Safety and Efficacy of a Novel Saw Palmetto (Serenoa repens) Extract for Promoting Hair Growth in Adults With Self-Perceived Thinning Hair: 180-Day Results.
    Ablon G · Journal of cosmetic dermatology · 2026
    Randomized trial60 participantsHair Health forSaw Palmetto
  4. Beyond Minoxidil: Off-Label Therapies for Male Androgenetic Alopecia-A Systematic Review with Network Meta-Analyses.
    Gupta AK; Compton SAH; Liddy A; Talukder M; Wang T; Bamimore MA · Medicina (Kaunas, Lithuania) · 2026
    Meta-analysis50 participants23 studies pooledHair Health forSaw Palmetto
  5. Comparitive effectiveness of finasteride vs Serenoa repens in male androgenetic alopecia: a two-year study.
    Rossi A; Mari E; Scarno M; Garelli V; Maxia C; Scali E; Iorio A; Carlesimo M · International journal of immunopathology and pharmacology · 2013
    Non-randomized trial100 participantsHair Health forSaw Palmetto
  6. Beyond Efficacy: 0.6% Selenium Disulfide Shampoo Matches 2% Ketoconazole for Seborrheic Dermatitis with Superior Cosmesis.
    Farris PK; Barbosa V; Houshman EB; Kovylkina N · Journal of drugs in dermatology : JDD · 2026
    Randomized trial87 participantsHair Health forSelenium
  7. Selenium Disulfide-based shampoo applied for 4 weeks significantly improves dandruff and seborrheic dermatitis.
    Turcu G; Artenie C; Nowicka D; Arenbergerová M; Lazaridou E; Khobzei K; Ataseven A; Part M; Leclerc-Mercier S · European journal of dermatology : EJD · 2023
    Observational study1,407 participantsHair Health forSelenium
  8. A Comparative Randomized Clinical Study Assessing the Efficacy of a 1% Selenium Disulfide-Based Shampoo versus 2% Ketoconazole Shampoo in Subjects with Moderate to Severe Scalp Seborrheic Dermatitis.
    Barbosa V; Melo DF; Vañó-Galván S; Lutchmanen-Kolanthan V; Sant'Anna B; Leclerc-Mercier S; Reygagne P · Skin appendage disorders · 2025
    Randomized trial64 participantsHair Health forSelenium
  9. Changes of serum trace elements level in patients with alopecia areata: A meta-analysis.
    Jin W; Zheng H; Shan B; Wu Y · The Journal of dermatology · 2018
    Meta-analysis764 participantsHair Health forSelenium
  10. Scientific opinion on the tolerable upper intake level for selenium.
    EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA); Turck D; Bohn T; Castenmiller J; de Henauw S; Hirsch-Ernst KI; Knutsen HK; Maciuk A; Mangelsdorf I; McArdle HJ; Peláez C; Pentieva K; Siani A; Thies F; Tsabouri S; Vinceti M; Aggett P; Crous Bou M; Cubadda F; Ciccolallo L; de Sesmaisons Lecarré A; Fabiani L; Titz A; Naska A · EFSA journal. European Food Safety Authority · 2023
    Systematic reviewHair Health forSelenium
  11. The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial.
    Berger RS; Fu JL; Smiles KA; Turner CB; Schnell BM; Werchowski KM; Lammers KM · The British journal of dermatology · 2003
    Randomized trial200 participantsHair Health forZinc
  12. Incubatory environment of the scalp impacts pre-emergent hair to affect post-emergent hair cuticle integrity.
    Schwartz JR; Henry JP; Kerr KM; Flagler MJ; Page SH; Redman-Furey N · Journal of cosmetic dermatology · 2018
    Randomized trialHair Health forZinc
  13. A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos.
    Draelos ZD; Kenneally DC; Hodges LT; Billhimer W; Copas M; Margraf C · The journal of investigative dermatology. Symposium proceedings · 2006
    Randomized trial40 participantsHair Health forZinc
  14. BMI and levels of zinc, copper in hair, serum and urine of Turkish male patients with androgenetic alopecia.
    Ozturk P; Kurutas E; Ataseven A; Dokur N; Gumusalan Y; Gorur A; Tamer L; Inaloz S · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2015
    Case-control study216 participantsHair Health forZinc
  15. Analysis of serum zinc and copper concentrations in hair loss.
    Kil MS; Kim CW; Kim SS · Annals of dermatology · 2013
    Case-control study342 participantsHair Health forZinc
  16. Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial.
    Goldson AJ; Fairweather-Tait SJ; Armah CN; Bao Y; Broadley MR; Dainty JR; Furniss C; Hart DJ; Teucher B; Hurst R · PloS one · 2011
    Randomized trial119 participantsImmunity forSelenium
  17. Effect of selenium on immune response against hepatitis B vaccine with accelerated method in insulin-dependent diabetes mellitus patients.
    Janbakhsh A; Mansouri F; Vaziri S; Sayad B; Afsharian M; Rahimi M; Shahebrahimi K; Salari F · Caspian journal of internal medicine · 2013
    Randomized trial62 participantsImmunity forSelenium
  18. Chemoprevention trial of human hepatitis with selenium supplementation in China.
    Yu SY; Li WG; Zhu YJ; Yu WP; Hou C · Biological trace element research · 1990
    Non-randomized trial20,847 participantsImmunity forSelenium
  19. Selenium nanoparticles as adjunctive therapy in sepsis: A pilot randomized clinical trial.
    Gu WJ; Huang W; Zhao FZ; Yuan XK; Jin K; Chen JL; Zhang CY; Huang Y; He L; Zhuang H; Yin HY; Chen T · Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2026
    Randomized trial70 participantsImmunity forSelenium
  20. Selenium supplementation in patients with autoimmune thyroiditis decreases thyroid peroxidase antibodies concentrations.
    Gärtner R; Gasnier BC; Dietrich JW; Krebs B; Angstwurm MW · The Journal of clinical endocrinology and metabolism · 2002
    Randomized trial70 participantsImmunity forSelenium