No Flush Niacin 500 mg

No Flush Niacin 500 mg

Natural Factors4.7 (970 ratings)
Format:Capsule Quantity: 90 Capsule(s) · 90 servings
Goals
$16.07 $0.17 per serving

Product analysis

85 out of 100

No Flush Niacin 500 mg is an inexpensive option for supplying niacin when intake is low. The named no-flush form should not be assumed to provide the cardiovascular effects associated with other niacin preparations.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality93

Inositol hexaniacinate clearly identifies the niacin preparation. Reliable form-quality information is unavailable for its separately listed inositol contribution.

Ingredient Transparency100

The amounts and forms of both listed actives are disclosed. That makes the preparation easier to distinguish from other types of niacin.

Value For Money100

The full serving offers favorable value for its named niacin preparation. That price advantage does not establish extra skin or cardiovascular benefit.

Customer Satisfaction81

Customer feedback is strongly positive. Several hundred ratings provide a useful base of customer feedback.

Product Focus31

The clearest role is nutritional support for normal skin maintenance when intake is low. The no-flush form cannot be treated as equivalent to other niacin preparations for cardiovascular purposes.

Format
Capsule
Container
90 Capsule(s)
Per serving
$0.17
Customer rating
4.7 · 970 ratings
Report analysis

Goals

Cardiovascular Support
Impact
Limited evidence
F Ingredient FitF PathwaysF EvidenceF Formulation Logic
Niacin · 500 mg

No Flush Niacin declares 500 mg of inositol hexaniacinate per serving, but that form is not counted for this cardiovascular goal in the saved profile. As a result, no ingredient reaches an effective counted amount and the product has no pathway coverage here. That does not establish that the product is clinically ineffective.

How this product is rated for Cardiovascular Support

Ingredient fit28

The product centers on niacin, but its inositol-hexaniacinate preparation has no counted cardiovascular role in the supplied profile.
Goal fit
Niacin relates to lipid metabolism, but this preparation receives no cardiovascular contribution here.
Dose adequacy
The 500 mg amount is clear, but this form does not qualify for a counted dose.

Pathways0

No selected lipid or vascular pathway receives a counted contribution from this preparation.
Depth
No pathway has counted coverage.
Breadth
None of the target pathways reaches the coverage threshold.

Evidence0

No ingredient reaches an effective counted amount to connect the product to the supplied evidence.
Evidence strength
No ingredient reaches an effective amount for this goal.
Studied preparation
No qualifying preparation appears at an effective counted amount.

Formulation logic35

There is no eligible ingredient to establish partner or effective-dose support, and no conflict is matched.
Partner coverage
No credited ingredient works alone or with a qualifying partner in this profile.
Conflicts
No matching conflict is recorded.
Effective doses
No credited ingredient reaches the effective-dose threshold.
Study evidence
Niacin Supportive 136 studies
Skin Health
Impact
Moderate effect
B+ Ingredient FitF PathwaysC EvidenceA+ Formulation Logic

Niacin contributes to normal skin maintenance when intake is inadequate. The 500 mg declaration has full dose support in the saved assessment, while the no-flush description does not establish added skin benefit or equivalence to the preparations used for other niacin-related outcomes.

How this product is rated for Skin Health

Ingredient fit82

The relevant ingredients provide a moderately focused skin contribution. The counted amounts have full dose support in the saved assessment, without implying added benefit at higher amounts.
Goal fit
The relevant ingredients provide a moderately focused skin contribution.
Dose adequacy
The counted amounts have full dose support in the saved assessment, without implying added benefit at higher amounts.

Pathways0

The findings reflect nutritional support without direct coverage of the assessed cosmetic mechanisms.
Depth
The findings reflect nutritional support without direct coverage of the assessed cosmetic mechanisms.
Breadth
No assessed skin aspect reaches the saved threshold for substantial coverage.

Evidence61

Vitamin B3 (Niacin) provides the strongest evidence contribution in the saved findings, with the preparation and nutritional context affecting applicability. The counted ingredients match preparations represented in the supplied evidence.
Evidence strength
Vitamin B3 (Niacin) provides the strongest evidence contribution in the saved findings, with the preparation and nutritional context affecting applicability.
Studied preparation
The counted ingredients match preparations represented in the supplied evidence.

Formulation logic100

No required partner is missing and no assessed conflict was identified. All counted ingredients pass the saved minimum amount check, although their support differs.
Partner coverage
No required supporting partner is missing for the counted ingredients.
Conflicts
No assessed ingredient conflict was identified in the supplied findings.
Effective doses
All counted ingredients pass the saved minimum amount check, although their support differs.
Study evidence
Niacin Supportive 61 studies

Ingredients

IngredientAmount per servingScore
Niacin (Inositol Hexaniacinate)
500 mg 73
Inositol (Inositol Hexaniacinate)
120 mg
Gluten Free Adults 18–50 Dairy Free Sugar Free
Report overview
C- Active Ingredient Quality & BioavailabilityB Dose, Safety & Label TransparencyA+ Value
A serving supplies 500 mg of niacin. The cost per serving is low. The form is Inositol Hexanicotinate. The amount and form are available for comparison.
How this ingredient is rated

Active Ingredient Quality & Bioavailability57

The form is Inositol Hexanicotinate.
Niacin Form & Goal Alignment
The form is Inositol Hexanicotinate.
Precursor Source Quality
The listed niacin form is Inositol Hexanicotinate.

Dose, Safety & Label Transparency75

A serving supplies 500 mg of niacin. The label says no flush.
Clarity of Chemical Form
The form is Inositol Hexanicotinate.
Form-Specific Dosage Efficacy
A serving supplies 500 mg of niacin.
Flush Risk & Safety Labeling
The label says no flush.

Value100

The cost per serving is low.
Price Per Effective Serving
The cost per serving is low.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The current state of niacin in cardiovascular disease prevention: a systematic review and meta-regression.
    Lavigne PM; Karas RH · Journal of the American College of Cardiology · 2013
    Meta-analysis9,959 participants11 studies pooledCardiovascular Support forNiacin
  2. Effects of niacin on apo A1 and B levels: a systematic review and meta-analysis of randomised controlled trials.
    Saboori S; Yousefi Rad E; Tammam J; Thondre PS; Coe S · The British journal of nutrition · 2024
    Meta-analysis12 studies pooledCardiovascular Support forNiacin
  3. Effect of lipid-lowering therapies on lipoprotein(a) levels: a comprehensive meta-analysis of randomized controlled trials.
    Xie S; Galimberti F; Olmastroni E; Carugo S; Catapano AL; Casula M; META-LIPID Group · Atherosclerosis · 2025
    Meta-analysis145,314 participants147 studies pooledCardiovascular Support forNiacin
  4. Extended-release niacin vs gemfibrozil for the treatment of low levels of high-density lipoprotein cholesterol. Niaspan-Gemfibrozil Study Group.
    Guyton JR; Blazing MA; Hagar J; Kashyap ML; Knopp RH; McKenney JM; Nash DT; Nash SD · Archives of internal medicine · 2000
    Randomized trial173 participantsCardiovascular Support forNiacin
  5. Equivalent efficacy of a time-release form of niacin (Niaspan) given once-a-night versus plain niacin in the management of hyperlipidemia.
    Knopp RH; Alagona P; Davidson M; Goldberg AC; Kafonek SD; Kashyap M; Sprecher D; Superko HR; Jenkins S; Marcovina S · Metabolism: clinical and experimental · 1998
    Randomized trial223 participantsCardiovascular Support forNiacin
  6. The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer.
    Hakozaki T; Minwalla L; Zhuang J; Chhoa M; Matsubara A; Miyamoto K; Greatens A; Hillebrand GG; Bissett DL; Boissy RE · The British journal of dermatology · 2002
    Randomized trial138 participantsSkin Health forNiacin
  7. Niacinamide: A B vitamin that improves aging facial skin appearance.
    Bissett DL; Oblong JE; Berge CA · Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2005
    Randomized trial50 participantsSkin Health forNiacin
  8. The clinical anti-aging effects of topical kinetin and niacinamide in Asians: a randomized, double-blind, placebo-controlled, split-face comparative trial.
    Chiu PC; Chan CC; Lin HM; Chiu HC · Journal of cosmetic dermatology · 2008
    Randomized trial52 participantsSkin Health forNiacin
  9. A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention.
    Chen AC; Martin AJ; Choy B; Fernández-Peñas P; Dalziell RA; McKenzie CA; Scolyer RA; Dhillon HM; Vardy JL; Kricker A; St George G; Chinniah N; Halliday GM; Damian DL · The New England journal of medicine · 2015
    Randomized trial386 participantsSkin Health forNiacin
  10. Nicotinamide for Skin Cancer Chemoprevention.
    Breglio KF; Knox KM; Hwang J; Weiss R; Maas K; Zhang S; Yao L; Madden C; Xu Y; Hartman RI; Wheless L · JAMA dermatology · 2025
    Cohort study33,822 participantsSkin Health forNiacin