Product analysis
Natural E-400 pairs natural vitamin E forms with selenium, which supports normal antioxidant and immune functions and may help when intake is low. The proportions of the vitamin E forms are not disclosed, making the mix harder to compare.
AI assessment of the formula, label and price. How scoring works
Nutrient Quality92
Natural vitamin E forms and selenium yeast are favorable choices for ingredient quality. The vitamin E mix remains less precise because the proportions of its forms are unknown.
Ingredient Transparency80
Ingredient amounts and forms are named, making much of the label clear. The proportions within the vitamin E mix are missing, so the exact balance cannot be checked.
Value For Money44
Value is strongest for the natural vitamin E forms. Selenium is relatively expensive for the amount supplied, making the combination less attractive if selenium is your main aim.
Customer Satisfaction78
Customer feedback is especially positive. A few hundred ratings give it a broader base of feedback, although they do not establish health benefits.
Product Focus69
Normal antioxidant and immune functions are the clearest roles, especially when selenium intake is low. Extra benefits for eye, heart or inflammation-related concerns remain uncertain when intake is adequate.
- Format
Softgel - Container
- 120 Softgel(s)
- Per serving
- $0.30
- Customer rating
- 4.9 · 238 ratings
Goals
Ingredients
| Ingredient | Amount per serving | Score |
|---|---|---|
Vitamin E (D-Alpha-Tocopherol) | 400 IU | |
Selenium (Selenium Yeast) | 100 mcg | |
natural Mixed Tocopherols (D-Beta Tocopherol, D-Delta-Tocopherol, D-Gamma-Tocopherol) | 48 mg |
How this ingredient is rated
Active Ingredient Quality & Bioavailability77
Natural (d-alpha) vs. Synthetic (dl-alpha)
Mixed Tocopherol Isomer Diversity
Tocotrienol Complex Inclusion
Dose, Safety & Label Transparency85
Therapeutic Dosage Range
Label Transparency and Isomer Specificity
Value100
Cost per Natural-Form Therapeutic Serving
How this ingredient is rated
Active Ingredient Quality & Bioavailability81
Selenium Chemical Form
Form Transparency & Isomer Specificity
Dose, Safety & Label Transparency88
Dosage Efficacy Sweet Spot
Safety Margin & UL Adherence
Value30
Price per 200 mcg Serving
Alternative products
Sources
Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.
- Effect of supplementation with high-selenium yeast on plasma lipids: a randomized trial.
- Association of selenium and cadmium with heart failure and mortality based on the National Health and Nutrition Examination Survey.
- Higher serum selenium concentration is associated with lower risk of all-cause and cardiovascular mortality among individuals with chronic kidney disease: A population-based cohort study of NHANES.
- Selenium status in the body and cardiovascular disease: a systematic review and meta-analysis.
- Associations of selenium status with all-cause and cause-specific mortality: a systematic review and meta-analysis of cohort studies.
- Supplementation with vitamin E alone is associated with reduced myocardial infarction: a meta-analysis.
- Vitamin E ameliorates blood cholesterol level and alters gut microbiota composition: A randomized controlled trial.
- Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial.
- Independent and combined associations of dietary antioxidant exposure with all-cause and cause-specific mortality in the general population.
- Tocotrienol rich fraction supplementation improved lipid profile and oxidative status in healthy older adults: A randomized controlled study.
- Dietary Antioxidants, Circulating Antioxidant Concentrations, Total Antioxidant Capacity, and Risk of All-Cause Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Observational Studies.
- The efficacy and safety of selenium supplementation versus placebo in the treatment of Graves' orbitopathy: A systematic review and meta-analysis of randomised controlled trials.
- Associations of plasma metal concentrations with the risks of all-cause and cardiovascular disease mortality in Chinese adults.
- Updates on clinical studies of selenium supplementation in radiotherapy.
- Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction: A vehicle-controlled, randomized clinical trial.
- Efficacy and safety of AZR-MD-001 selenium sulfide ophthalmic ointment in adults with meibomian gland dysfunction over six months of treatment: A Phase 2, vehicle-controlled, randomized extension trial.
- AZR-MD-001 0.5% selenium sulfide ophthalmic ointment for the treatment of contact lens discomfort: A vehicle-controlled, randomized, clinical trial.
- The effect of a biweekly novel selenium sulfide-containing topical treatment in symptomatic contact lens wearers: An exploratory study.
- Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration.
- Dietary n-3 Fatty Acid, α-Tocopherol, Zinc, vitamin D, vitamin C, and β-carotene are Associated with Age-Related Macular Degeneration in Japan.