Folic Acid B6 & B12

Folic Acid B6 & B12

Mason Natural4.8 (2,835 ratings)
Format:Tablet Quantity: 90 Tablet(s) · 90 servings
Goals
$5.78 $0.06 per serving

Product analysis

62 out of 100

Folic Acid B6 & B12 offers a focused B-vitamin combination with favorable value for its B6 content, while its practical heart-related benefit remains uncertain.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality50

The vitamin B6 form is clearly identified. Folate is unspecified, while the quality of the named B12 and calcium preparations remains uncertain.

Ingredient Transparency91

Ingredient quantities and most forms are listed. The folate form remains unspecified, and source quantities do not by themselves settle the amount delivered per serving.

Value For Money55

The vitamin B6 contribution compares favorably on cost. Value for folate, B12 and calcium cannot be judged as confidently.

Customer Satisfaction89

Customer feedback is very favorable across a substantial review pool. Those opinions describe satisfaction rather than demonstrating heart-related benefits.

Product Focus30

The short ingredient list has a clear B-vitamin theme. Uncertain amounts per serving prevent a confident conclusion about its heart-related contribution.

Format
Tablet
Container
90 Tablet(s)
Per serving
$0.06
Customer rating
4.8 · 2,835 ratings
Report analysis

Goals

Impact
Situational effect
D+ Ingredient FitF PathwaysF EvidenceB Formulation Logic
Folate · 667 mcg DFEVitamin B12 · 100 mcg
Study evidence
Folate Supportive 80 studies

Ingredients

IngredientAmount per servingScore
Vitamin B6 (Pyridoxine Hydrochloride)
50 mg 75
Folate
667 mcg DFE
Vitamin B12 (Cyanocobalamin)
100 mcg 21
Calcium (Calcium Phosphate)
44 mg
Gluten Free Adults 18–50
Report overview
A+ Ingredient Form & Label QualityF Dose, Safety & Label TransparencyA+ Value
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyF Value
A serving provides 100 mcg of B12 as cyanocobalamin. The whole-product price works out to about $0.64 per 1,000 mcg of B12.
How this ingredient is rated

Active Ingredient Quality & Bioavailability10

The B12 is cyanocobalamin, which the evaluation distinguishes from bioactive forms.
Bioactive B12 Form Selection
The listed B12 form is cyanocobalamin.

Dose, Safety & Label Transparency37

The label identifies the form and lists 100 mcg of B12 per serving.
Therapeutic Dosage Level
A serving contains 100 mcg of vitamin B12.
Label and Form Transparency
The label identifies cyanocobalamin and specifies the B12 amount per serving.

Value10

The whole-product price works out to about $0.64 per 1,000 mcg of B12.
Price per 1,000 mcg B12
The whole-product price works out to about $0.64 per 1,000 mcg of B12.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Intakes of Folate, Vitamin B6, and Vitamin B12 in Relation to All-Cause and Cause-Specific Mortality: A National Population-Based Cohort.
    Bo Y; Xu H; Zhang H; Zhang J; Wan Z; Zhao X; Yu Z · Nutrients · 2022
    Cohort study55,569 participantsEveryday Health forFolate
  2. The responsiveness of plasma homocysteine to small increases in dietary folic acid: a primary care study.
    Schorah CJ; Devitt H; Lucock M; Dowell AC · European journal of clinical nutrition · 1998
    Randomized trial119 participantsEveryday Health forFolate
  3. Associations of Serum Folate and Homocysteine Concentrations with All-Cause, Cardiovascular Disease, and Cancer Mortality in Men and Women in Korea: the Cardiovascular Disease Association Study.
    Song S; Song BM; Park HY · The Journal of nutrition · 2023
    Cohort study21,260 participantsEveryday Health forFolate
  4. The concept of folic acid supplementation and its role in prevention of neural tube defect among pregnant women: PRISMA.
    Seyoum Tola F · Medicine · 2024
    Systematic reviewEveryday Health forFolate
  5. Systematic review of adverse health outcomes associated with high serum or red blood cell folate concentrations.
    Colapinto CK; O'Connor DL; Sampson M; Williams B; Tremblay MS · Journal of public health (Oxford, England) · 2017
    Systematic review71,847 participants46 studies pooledEveryday Health forFolate
  6. Oral Vitamin B12 versus Placebo for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Gynecological Cancer Patients: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Insin P; Chaiwongsa T; Prueksaritanond N · Asian Pacific journal of cancer prevention : APJCP · 2026
    Randomized trial40 participantsEveryday Health forVitamin B12
  7. Vitamin B12 Supplementation in Diabetic Neuropathy: A 1-Year, Randomized, Double-Blind, Placebo-Controlled Trial.
    Didangelos T; Karlafti E; Kotzakioulafi E; Margariti E; Giannoulaki P; Batanis G; Tesfaye S; Kantartzis K · Nutrients · 2021
    Randomized trial90 participantsEveryday Health forVitamin B12
  8. A single-center randomized controlled trial of local methylcobalamin injection for subacute herpetic neuralgia.
    Xu G; Lv ZW; Feng Y; Tang WZ; Xu GX · Pain medicine (Malden, Mass.) · 2014
    Randomized trial98 participantsEveryday Health forVitamin B12
  9. Local Injection of Methylcobalamin Combined with Lidocaine for Acute Herpetic Neuralgia.
    Xǔ G; Xu S; Tang WZ; Xú G; Cheng C; Xu J · Pain medicine (Malden, Mass.) · 2017
    Randomized trial204 participantsEveryday Health forVitamin B12
  10. The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis.
    Nozari E; Ghavamzadeh S; Razazian N · Clinical nutrition research · 2022
    Clinical trial50 participantsEveryday Health forVitamin B12