Niacin 500 mg

Niacin 500 mg

NOW4.6 (6,961 ratings)
Format:Tablet Quantity: 250 Tablet(s) · 250 servings
Goals
$15.10 $0.06 per serving

Product analysis

51 out of 100

Niacin 500 mg has a possible connection to blood-fat changes, but its exact niacin form is unclear. That matters because different niacin forms do not share the same effects.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality0

The broad vitamin B3 description does not establish the exact niacin form. That limits confidence in applying benefits associated with a specific preparation.

Ingredient Transparency100

The serving amount is clear and a vitamin B3 form description is provided. The description is still too broad to distinguish between different niacin preparations.

Value For Money40

Value is limited by uncertainty about the exact niacin preparation. A serving-cost comparison alone cannot show that it provides the effects expected from a particular form.

Customer Satisfaction87

Customer ratings are favorable across a large review pool. They do not establish effects on blood fats or cardiovascular outcomes.

Product Focus68

The formula focuses on niacin, with a possible connection to blood-fat measurements. Changes in those measurements do not establish fewer cardiovascular events, and the unclear form limits expectations.

Format
Tablet
Container
250 Tablet(s)
Per serving
$0.06
Customer rating
4.6 · 6,961 ratings
Report analysis

Goals

Heart Health
Impact
Moderate effect
A+ Ingredient FitF PathwaysC EvidenceA+ Formulation Logic
Study evidence
Niacin Supportive 105 studies
Cardiovascular Support
Impact
High effect
A+ Ingredient FitD+ PathwaysB- EvidenceA+ Formulation Logic
Niacin · 500 mg
Study evidence
Niacin Supportive 136 studies

Ingredients

IngredientAmount per servingScore
Niacin (Vitamin B3)
500 mg 37
Gluten Free Adults 18–50 Vegan Kosher Dairy Free Vegetarian
Report overview
F Active Ingredient Quality & BioavailabilityF Dose, Safety & Label TransparencyD- Value
A serving provides 500 mg of niacin, and the cost per serving is low, though its form is unknown. The niacin form is unknown. The unknown form makes its effects and flushing potential harder to judge.
How this ingredient is rated

Active Ingredient Quality & Bioavailability36

The niacin form is unknown, so its fit for a particular goal is unclear.
Niacin Form & Goal Alignment
The form is unknown, so its fit for a specific goal is unclear.
Precursor Source Quality
The source is unknown, so its precursor form cannot be established.

Dose, Safety & Label Transparency37

The serving contains 500 mg of niacin. Its chemical form is unspecified.
Clarity of Chemical Form
The chemical form of niacin is not specified.
Form-Specific Dosage Efficacy
The serving provides 500 mg of niacin, but the unknown form limits a form-specific comparison.
Flush Risk & Safety Labeling
A flushing warning is present, but the niacin form is unknown.

Value40

The cost per serving is low, though its form is unknown.
Price Per Effective Serving
The cost per serving is low, though its form is unknown.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. The current state of niacin in cardiovascular disease prevention: a systematic review and meta-regression.
    Lavigne PM; Karas RH · Journal of the American College of Cardiology · 2013
    Meta-analysis9,959 participants11 studies pooledCardiovascular Support forNiacin
  2. Effects of niacin on apo A1 and B levels: a systematic review and meta-analysis of randomised controlled trials.
    Saboori S; Yousefi Rad E; Tammam J; Thondre PS; Coe S · The British journal of nutrition · 2024
    Meta-analysis12 studies pooledCardiovascular Support forNiacin
  3. Effect of lipid-lowering therapies on lipoprotein(a) levels: a comprehensive meta-analysis of randomized controlled trials.
    Xie S; Galimberti F; Olmastroni E; Carugo S; Catapano AL; Casula M; META-LIPID Group · Atherosclerosis · 2025
    Meta-analysis145,314 participants147 studies pooledCardiovascular Support forNiacin
  4. Extended-release niacin vs gemfibrozil for the treatment of low levels of high-density lipoprotein cholesterol. Niaspan-Gemfibrozil Study Group.
    Guyton JR; Blazing MA; Hagar J; Kashyap ML; Knopp RH; McKenney JM; Nash DT; Nash SD · Archives of internal medicine · 2000
    Randomized trial173 participantsCardiovascular Support forNiacin
  5. Equivalent efficacy of a time-release form of niacin (Niaspan) given once-a-night versus plain niacin in the management of hyperlipidemia.
    Knopp RH; Alagona P; Davidson M; Goldberg AC; Kafonek SD; Kashyap M; Sprecher D; Superko HR; Jenkins S; Marcovina S · Metabolism: clinical and experimental · 1998
    Randomized trial223 participantsCardiovascular Support forNiacin
  6. Differential effect of two nicotinic acid preparations on low-density lipoprotein subclass distribution in patients classified as low-density lipoprotein pattern A, B, or I.
    Superko HR; McGovern ME; Raul E; Garrett B · The American journal of cardiology · 2004
    Randomized trial180 participantsHeart Health forNiacin
  7. The ARBITER 6-HALTS Trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6-HDL and LDL Treatment Strategies in Atherosclerosis): final results and the impact of medication adherence, dose, and treatment duration.
    Villines TC; Stanek EJ; Devine PJ; Turco M; Miller M; Weissman NJ; Griffen L; Taylor AJ · Journal of the American College of Cardiology · 2010
    Randomized trial315 participantsHeart Health forNiacin
  8. The effects of extended-release niacin on carotid intimal media thickness, endothelial function and inflammatory markers in patients with the metabolic syndrome.
    Thoenes M; Oguchi A; Nagamia S; Vaccari CS; Hammoud R; Umpierrez GE; Khan BV · International journal of clinical practice · 2008
    Randomized trial50 participantsHeart Health forNiacin
  9. Effect of niacin therapy on cardiovascular outcomes in patients with coronary artery disease.
    Duggal JK; Singh M; Attri N; Singh PP; Ahmed N; Pahwa S; Molnar J; Singh S; Khosla S; Arora R · Journal of cardiovascular pharmacology and therapeutics · 2010
    Meta-analysis5,137 participants7 studies pooledHeart Health forNiacin
  10. Effect of niacin on endothelial function: a systematic review and meta-analysis of randomized controlled trials.
    Sahebkar A · Vascular medicine (London, England) · 2014
    Meta-analysis441 participants7 studies pooledHeart Health forNiacin