Alpha-GPC 300 mg

Alpha-GPC 300 mg

Swanson4.6 (703 ratings)
Format:Capsule Quantity: 60 Capsule(s) · 60 servings
Goals
$31.39 $0.52 per serving
iHerbLowest$31.39iHerb$31.39Amazon$119.28

Product analysis

52 out of 100

Alpha-GPC 300 mg may support selected attention tasks, but the findings are preliminary and tied to particular preparations.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality20

The Alpha-GPC preparation is not specified, leaving its form quality unclear. The declared amount cannot by itself establish equivalence with a particular active preparation.

Ingredient Transparency63

The Alpha-GPC amount is disclosed. Missing preparation details make comparison with specific active materials less precise.

Value For Money70

Alpha-GPC offers moderate value for the declared amount. The unspecified preparation makes comparisons with identified active materials less certain.

Customer Satisfaction77

Customer feedback is positive. The smaller review base gives a less established picture of satisfaction.

Product Focus51

One active ingredient keeps the formula simple. Evidence for attention and related tasks comes from a small acute exercise setting, leaving wider everyday cognitive benefits uncertain.

Format
Capsule
Container
60 Capsule(s)
Per serving
$0.52
Customer rating
4.6 · 703 ratings
Report analysis

Goals

Productivity Boost
Productivity Boost
Impact
Lower effect
A Ingredient FitF PathwaysF EvidenceA+ Formulation Logic
Alpha-GPC · 300 mg
Study evidence
Alpha-GPC Supportive 2 studies
Brain Health
Brain Health
Impact
Moderate effect
B- Ingredient FitF PathwaysF EvidenceA+ Formulation Logic
Alpha-GPC · 300 mg

Alpha-GPC supplies choline related to acetylcholine signalling, which is involved in attention and memory. The 300 mg serving provides a partial amount relative to the supplied comparison, with limited preparation-specific attention evidence.

How this product is rated for Brain Health

Ingredient fit74

The relevant ingredients fit the goal, with the declared amounts and broader formula focus shaping their contribution.
Goal fit
The relevant ingredients give the formula a clear connection to brain health.
Dose adequacy
The assessed amounts provide partial support within the supplied comparison range.

Pathways10

The main assessed contribution is concentrated in acetylcholine signalling.
Depth
The strongest saved finding concerns acetylcholine signalling, with partial coverage.
Breadth
The saved findings remain narrow and do not show strong coverage across several brain-health processes.

Evidence35

Alpha-GPC has limited evidence for specific attention tasks. The assessed preparation is not identified as the specific material used in the supporting trials.
Evidence strength
Alpha-GPC has limited evidence for specific attention tasks.
Studied preparation
The assessed preparation is not identified as the specific material used in the supporting trials.

Formulation logic100

The assessed ingredients need no additional partner, and no configured conflicts were found.
Partner coverage
The assessed ingredients can contribute without an additional required partner.
Conflicts
No configured ingredient conflict was identified in the supplied assessment.
Effective doses
The ingredients included in this saved finding meet its amount threshold.
Study evidence
Alpha-GPC Supportive 12 studies
Mental Focus
Mental Focus
Impact
Lower effect
A Ingredient FitF PathwaysF EvidenceA+ Formulation Logic
Alpha-GPC · 300 mg
Study evidence
Alpha-GPC Supportive 1 study
Cognitive Support
Cognitive Support
Impact
Moderate effect
A Ingredient FitF PathwaysF EvidenceA+ Formulation Logic
Alpha-GPC · 300 mg

Alpha-GPC connects with acetylcholine signalling and preliminary findings on selected attention and executive tasks. The 300 mg serving is near the lower active amount tested, but an unqualified material declaration cannot be assumed to match that active preparation. Evidence is limited to a small acute exercise-related setting.

How this product is rated for Cognitive Support

Ingredient fit91

1 relevant ingredient contribute to the goal, with no other assessed active ingredients reducing the focus. The assessed amounts are close to the full comparison amounts used in the saved findings.
Goal fit
1 relevant ingredient contribute to the goal, with no other assessed active ingredients reducing the focus.
Dose adequacy
The assessed amounts are close to the full comparison amounts used in the saved findings.

Pathways17

The clearest connection is acetylcholine signalling, with a limited contribution in the saved findings.
Depth
The clearest connection is acetylcholine signalling, with a limited contribution in the saved findings.
Breadth
Support remains too limited to show meaningful breadth across the assessed cognitive pathways.

Evidence28

Alpha-GPC provides the strongest evidence contribution at an assessed amount, with benefits limited to the populations and outcomes described in the supplied evidence. Alpha-GPC is not matched to the preparations used in the relevant trials, which limits how directly those findings apply.
Evidence strength
Alpha-GPC provides the strongest evidence contribution at an assessed amount, with benefits limited to the populations and outcomes described in the supplied evidence.
Studied preparation
Alpha-GPC is not matched to the preparations used in the relevant trials, which limits how directly those findings apply.

Formulation logic100

No conflict was identified in the supplied checks. 1 of 1 relevant ingredients meet the saved minimum amount criterion.
Partner coverage
The relevant ingredients can contribute alone or have the partners required by the saved findings.
Conflicts
No conflict was identified in the supplied checks.
Effective doses
1 of 1 relevant ingredients meet the saved minimum amount criterion.
Study evidence
Alpha-GPC Supportive 15 studies
Longevity
Longevity
Impact
Lower effect
B- Ingredient FitF PathwaysF EvidenceA+ Formulation Logic
Alpha-GPC · 300 mg
Study evidence
Alpha-GPC Not classified

No linked studies yet.

Ingredients

IngredientAmount per servingScore
Alpha Glycerylphosphorylcholine
300 mg 62
Adults 18–50
Report overview
Alpha-GPC · 300 mg OverallScore62
D- Active Ingredient Quality & BioavailabilityB+ Dose, Safety & Label TransparencyB- Value
Each serving provides 300 mg of Alpha-GPC. Based on the whole-product price, 300 mg of Alpha-GPC works out to about $0.52, a moderate price in this comparison.
How this ingredient is rated

Active Ingredient Quality & Bioavailability40

The saved facts identify Alpha-GPC without a branded or botanical source.
Patented/Branded Form and Source
Alpha-GPC is named, but the saved facts do not identify a branded or botanical source.

Dose, Safety & Label Transparency80

A serving provides 300 mg of active Alpha-GPC.
Active Alpha-GPC Dosage
A serving provides 300 mg of active Alpha-GPC.
Label Transparency & Yield Disclosure
The active Alpha-GPC amount is given as 300 mg per serving; no separate active-yield statement appears in the saved facts.

Value70

Based on the whole-product price, 300 mg of Alpha-GPC works out to about $0.52, a moderate price in this comparison.
Price per 300mg Active Alpha-GPC
Based on the whole-product price, 300 mg of Alpha-GPC works out to about $0.52, a moderate price in this comparison.
View ingredientView products
72 Performance

Genius Consciousness Watermelon

The Genius Brand

Alpha-GPC, acetyl-L-carnitine, phosphatidylserine, tyrosine, and lion's mane create broad cognitive coverage, giving it broader cognitive support than the original. Caffeine and methyliberine raise stimulant concerns, and the huperzine active yield is unclear.

73 Performance

Vital Brain Powder

Vital Nutrients

Alpha-GPC, phosphatidylserine, and acetyl-L-carnitine provide a concise cognitive blend in meaningful listed amounts, giving it broader cognitive support than the original. The serving cost is high, so the ingredient depth comes with poor value.

76 Performance

Natural Brain Enhancers

Doctor's Best

Branded Alpha-GPC and phosphatidylserine provide complementary choline and cell-membrane support, giving it broader cognitive support than the original. The active Alpha-GPC yield is not stated, and several calcium entries make the label harder to interpret.

78 Budget

Alpha GPC 300 mg

Jarrow Formulas

A clearly listed Alpha-GPC amount provides focused choline support without unrelated additions at a lower serving cost than the original. Generic sourcing, unconfirmed active yield, and no stated moisture protection limit certainty about ingredient quality.

72 Budget

Seventh Gear Your Mom's Lemonade

Axe & Sledge Supplements

No provided candidate in this slot costs less per serving than the original. Beta-alanine, betaine, creatine, caffeine, and two choline forms provide broad pre-workout coverage at a low serving cost, making it one of the closest available options. The added workout ingredients and caffeine make it less focused and may not suit stimulant-sensitive users.

77 Budget

Cognitex Basics

Life Extension

No provided candidate in this slot costs less per serving than the original. Alpha-GPC, phosphatidylserine, and blueberry combine choline, membrane, and antioxidant support in a softgel, making it one of the closest available options. The active Alpha-GPC yield is not stated, and the likely choline amount is modest.

75 Value

Alpha GPC 300 mg

NOW

A large listed Alpha-GPC material amount provides concentrated, single-ingredient choline support, delivering more useful cognitive or performance coverage for the serving cost than the original. The active yield and moisture protection are not stated, so the practical choline amount remains uncertain.

66 Value

Bucked Up Pre-Workout 'Merica Rocket Pop

DAS Labs

Citrulline malate and caffeine provide a practical performance base with beta-alanine and Alpha-GPC, delivering more useful cognitive or performance coverage for the serving cost than the original. The added workout ingredients and caffeine make it less focused and may not suit stimulant-sensitive users.

71 Value

High-Performance Pre-Workout Black Cherry

Pre JYM

Citrulline, creatine, amino acids, tyrosine, caffeine, and taurine provide broad, fully disclosed workout support, delivering more useful cognitive or performance coverage for the serving cost than the original. The added workout ingredients and caffeine make it less focused and may not suit stimulant-sensitive users.

Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. Activity of Choline Alphoscerate on Adult-Onset Cognitive Dysfunctions: A Systematic Review and Meta-Analysis.
    Sagaro GG; Traini E; Amenta F · Journal of Alzheimer's disease : JAD · 2023
    Meta-analysis8 studies pooledBrain Health Cognitive Support forAlpha-GPC
  2. Comparative study of choline alfoscerate as a combination therapy with donepezil: A mixed double-blind randomized controlled and open-label observation trial.
    Lee W; Kim M · Medicine · 2024
    Randomized trial119 participantsBrain Health Cognitive Support forAlpha-GPC
  3. Effects of choline alfoscerate on cognitive function and quality of life in type 2 diabetes: A double-blind, randomized, placebo-controlled trial.
    Sohn M; Park YH; Lim S · Diabetes, obesity & metabolism · 2025
    Randomized trial36 participantsBrain Health Cognitive Support forAlpha-GPC
  4. Acute Alpha-Glycerylphosphorylcholine Supplementation Enhances Cognitive Performance in Healthy Men.
    Kerksick CM · Nutrients · 2024
    Randomized trial20 participantsBrain Health Mental Focus Productivity Boost forAlpha-GPC
  5. Cognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial.
    De Jesus Moreno Moreno M · Clinical therapeutics · 2003
    Randomized trial261 participantsBrain Health forAlpha-GPC
  6. [Gliatilin in the Treatment of Cognitive Impairments Not Reaching the Level of Dementia: Meta-Analysis and Systematic Review].
    Voznyuk IA; Nepomnyashchiy IS; Kutkova AK; Tokareva DV; Prokhorova MV; Ovdiienko OA; Shusharina NN · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2025
    Meta-analysis10 studies pooledCognitive Support forAlpha-GPC
  7. Vertical Association Between Dietary Total Choline and L-alpha-glycerylphosphorylcholine and the Cognitive Function in Chinese Adults Aged over 55, Result from China Health and Nutrition Survey 1997-2018.
    Guan F; Jia X; Huang F; Zhang J; Wei Y; Li L; Bai J; Wang H · Nutrients · 2024
    Cohort study7,659 participantsCognitive Support forAlpha-GPC
  8. Treatment of dementia with neurotransmission modulation.
    Doggrell SA; Evans S · Expert opinion on investigational drugs · 2004
    Narrative reviewProductivity Boost forAlpha-GPC