St. John's Wort Extract 300 mg

St. John's Wort Extract 300 mg

Lake Avenue Nutrition4.6 (4,423 ratings)
Format:Capsule Quantity: 90 Capsule(s) · 90 servings
Goals
$8.83 $0.09 per serving
iHerbLowest$8.83Amazon$10.15

Product analysis

63 out of 100

St. John's Wort Extract 300 mg offers mood-focused support, with benefits depending on the extract and individual circumstances. It can change the effects of many medicines, making medicine compatibility a key consideration.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality40

Hypericin is named as a component of the extract. That detail alone does not establish equivalence to a particular preparation with demonstrated mood effects.

Ingredient Transparency100

The amount and named component are disclosed. That makes the basic preparation easier to compare, without establishing equivalence to other extracts.

Value For Money40

Value cannot be judged reliably from the available price information. An incomplete cost comparison does not establish that the extract is expensive or economical.

Customer Satisfaction86

Customer ratings are generally favorable. A large review pool gives satisfaction more context without demonstrating mood benefits.

Product Focus67

Mood is the formula’s clear focus, but the evidence concerns particular extracts in selected people. The single serving is below the daily exposure described for those preparations and does not establish a full regimen.

Format
Capsule
Container
90 Capsule(s)
Per serving
$0.09
Customer rating
4.6 · 4,423 ratings
Report analysis

Goals

Mood Support
Mood Support
Impact
High effect
B- Ingredient FitF PathwaysB+ EvidenceA+ Formulation Logic

St. John’s wort has evidence for depressive symptoms in diagnosed mild-to-moderate depression using defined extracts. The 300 mg serving is below the 900 mg daily exposure described for reviewed preparations, and one serving does not establish a daily regimen. Those findings do not demonstrate routine benefit in healthy adults or interchangeability of extracts. St. John’s wort can also alter the effects of many medicines.

How this product is rated for Mood Support

Ingredient fit73

St. John's Wort provide the main mood-related connections. The recognized ingredients are concentrated in this area.
Goal fit
The recognized ingredients are focused on mood-related roles; the product’s links to other goals also affect that focus.
Dose adequacy
The saved amount findings reflect the recognized ingredients’ declared serving amounts; unresolved amounts limit the comparison.

Pathways11

The strongest represented area is Monoamine signalling. Other areas do not reach the coverage threshold.
Depth
Monoamine signalling is the strongest represented area in the saved findings; this does not independently establish a mood effect.
Breadth
No area reaches the saved coverage threshold.

Evidence84

St. John's Wort leads the evidence finding. Its specific population and preparation limits remain relevant, even where the ingredient amount and preparation are recognized.
Evidence strength
St. John's Wort leads the saved evidence finding; its population and preparation limits still govern the mood claims that can be made.
Studied preparation
The saved findings recognize the qualifying preparations, but that does not make every form interchangeable or establish routine mood benefit.

Formulation logic100

The recognized ingredients meet the supplied partner requirements, with no specified ingredient conflict matched. All recognized ingredients meet the amount threshold used in these findings.
Partner coverage
The recognized ingredients can contribute independently or have the partner required by the supplied findings; no extra combination benefit is established.
Conflicts
No specified ingredient conflict was matched in the supplied findings; this does not establish medication compatibility.
Effective doses
The recognized ingredients meet the saved amount threshold; this is not proof that each serving produces a mood benefit.
Study evidence

Ingredients

IngredientAmount per servingScore
St. John's Wort aerial part extract (Hypericin)
 300 mg 100
Gluten Free Adults 18–50 Dairy Free Women
Report overview
St. John's Wort (Hypericin) · 300 mg OverallScore100
A+ Composition And Label Disclosure
The evaluation records an ingredient-specific warning for St. John's wort, but its wording is unavailable. Each serving lists 300 mg of St. John's wort.
How this ingredient is rated

Composition and Label Disclosure

Each serving lists 300 mg of St. John's wort; no composition rule was evaluated.

Composition and Label Disclosure100

An ingredient-specific warning is recorded in the saved evaluation, though its details are not supplied.
Explicit Label Detail
The saved facts indicate a specific warning, but do not provide its wording.

Commercial Price and Usability

A whole-product serving costs about $0.10; no price rule was evaluated.
View ingredientView products
88 Performance

Full Spectrum St. John's Wort Extract 600 mg

Planetary Herbals
A standardized, substantial Saint John’s wort blend offers focused mood support with stronger potency clarity than nonstandardized options; its extract quality and goal fit provide a clearer option when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
84 Performance

Feeling Positive St. John's Wort 300 mg

Sundown
Marker standardization supports consistent extract quality, though the daily amount is moderate; its extract quality and goal fit provide a clearer option when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
83 Performance

St. John's Wort Extract 300 mg

Lake Avenue Nutrition
A hypericin-standardized aerial-parts extract gives useful potency clarity and focused mood support, though one serving may provide only a partial daily dose; its extract quality and goal fit provide a clearer option when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
90 Budget

St. John's Wort Extract

Swanson Superior Herbs
Marker standardization supports consistent extract quality, though the daily amount is moderate; the lower serving cost improves economy when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
90 Budget

St. John's Wort 300 mg

NOW
Marker standardization supports consistent extract quality, though the daily amount is moderate; the lower serving cost improves economy when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
89 Budget

St. John's Wort 300 mg

California Gold Nutrition EuroHerbs
A hypericin-standardized extract gives useful potency clarity and focused mood support, though one serving may provide only a partial daily dose; the lower serving cost improves economy when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
86 Value

St. John's Wort 300 mg

Nature's Bounty
Marker standardization supports consistent extract quality, though the daily amount is moderate; the quality-to-cost balance is favorable when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
86 Value

Perika St. John's Wort

Nature's Way
The named extract supports consistent quality, though the daily amount is moderate; the quality-to-cost balance is favorable when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
83 Value

St. John's Wort

Paradise
Marker standardization supports consistent extract quality, though the daily amount is moderate; the quality-to-cost balance is favorable when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. St John's wort for major depression.
    Linde K; Berner MM; Kriston L · The Cochrane database of systematic reviews · 2009
    Systematic review5,489 participants29 studies pooledMood Support forSt. John's Wort
  2. Efficacy of St. John's wort extract WS 5570 in major depression: a double-blind, placebo-controlled trial.
    Lecrubier Y; Clerc G; Didi R; Kieser M · The American journal of psychiatry · 2002
    Randomized trial375 participantsMood Support forSt. John's Wort
  3. A systematic review and meta-analysis of Hypericum perforatum in depression: a comprehensive clinical review.
    Whiskey E; Werneke U; Taylor D · International clinical psychopharmacology · 2002
    Meta-analysis22 studies pooledMood Support forSt. John's Wort
  4. Efficacy and tolerability of hypericum extract WS 5572 versus placebo in mildly to moderately depressed patients. A randomized double-blind multicenter clinical trial.
    Kalb R; Trautmann-Sponsel RD; Kieser M · Pharmacopsychiatry · 2001
    Randomized trial72 participantsMood Support forSt. John's Wort
  5. Complementary therapies for clinical depression: an overview of systematic reviews.
    Haller H; Anheyer D; Cramer H; Dobos G · BMJ open · 2020
    Systematic review26 studies pooledMood Support forSt. John's Wort