St. John's Wort 300 mg

St. John's Wort 300 mg

California Gold Nutrition EuroHerbs4.6 (5,747 ratings)
Format:Capsule Quantity: 180 Capsule(s) · 180 servings
Goals
$14.00 $0.07 per serving
iHerbLowest$14.00Amazon$19.13

Product analysis

61 out of 100

St. John's Wort 300 mg is a mood supplement whose evidence depends on the particular extract used. It can weaken many medicines and interact with medicines that affect serotonin, making medication use a key suitability concern.

AI assessment of the formula, label and price. How scoring works

Nutrient Quality40

The hypericin detail helps identify the extract, but its ingredient quality remains uncertain. A clear absorption advantage cannot be confirmed.

Ingredient Transparency100

The serving amount is stated, making amount comparisons possible. Hypericin standardization provides another way to distinguish extracts.

Value For Money40

The value of the extract cannot be judged confidently. Clear amount and standardization details do not establish a price advantage.

Customer Satisfaction86

Customer ratings are generally positive. Feedback from 5,747 ratings gives a broad picture of satisfaction.

Product Focus55

The single-herb formula focuses on mood support, with evidence from specific extracts in people with diagnosed depression. A 300 mg serving alone does not match the 900 mg daily exposure behind those findings.

Format
Capsule
Container
180 Capsule(s)
Per serving
$0.07
Customer rating
4.6 · 5,747 ratings
Report analysis

Goals

Mood Support
Mood Support
Impact
High effect
B- Ingredient FitF PathwaysB+ EvidenceA+ Formulation Logic

St. John's wort extracts have evidence for improving symptoms in diagnosed mild-to-moderate depression, which does not establish routine mood benefit in healthy adults. This serving supplies 300 mg of standardized extract, below the 900 mg daily exposure used in the cited trials. Extract identity matters, and hypericin standardization alone does not make trial preparations interchangeable. St. John's wort can weaken many medicines and interact with serotonergic agents.

How this product is rated for Mood Support

Ingredient fit71

Relevant ingredients provide the mood connection, with the amount findings determining how much each contributes. Preparation and intake context still matter.
Goal fit
The relevant ingredients dominate the formula, although its links to other goals reduce its focus on mood.
Dose adequacy
The serving supplies only part of the amount used for the saved comparison.

Pathways11

The saved findings describe the functions represented by the relevant ingredients. Coverage of a mechanism alone does not establish a mood improvement.
Depth
The strongest saved contribution concerns monoamine signalling, with partial coverage from the relevant ingredients.
Breadth
No function reaches the saved breadth threshold at this amount.

Evidence84

The strongest ingredient evidence and the match to reviewed preparations determine this finding. Population and preparation limits remain relevant to expected mood effects.
Evidence strength
St. John's Wort provides the strongest saved evidence contribution; its population and outcome limitations still determine what benefit can be expected.
Studied preparation
The ingredients counted at sufficient amounts match the preparations accepted in the saved comparison.

Formulation logic100

The saved findings consider independent contributions, required partners and configured conflicts. Small or undisclosed amounts can limit individual contributions.
Partner coverage
The counted ingredients can contribute independently or have their required partner.
Conflicts
No configured ingredient conflict was identified in the supplied facts; this does not establish medication suitability.
Effective doses
All counted ingredients pass the saved minimum amount, which is a comparison threshold rather than proof of benefit.
Study evidence
Stress Relief
Stress Relief
Impact
Lower effect
A+ Ingredient FitF PathwaysD- EvidenceA+ Formulation Logic
Study evidence

Ingredients

IngredientAmount per servingScore
St. John's Wort Extract (Hypericin)
 300 mg 100
Gluten Free Adults 18–50 Dairy Free
Report overview
St. John's Wort (Hypericin) · 300 mg OverallScore100
A+ Composition And Label Disclosure
A serving lists 300 mg of St. John's wort extract. The evaluation records an ingredient-specific warning, but its wording is not available in the saved facts.
How this ingredient is rated

Composition and Label Disclosure

No separate source or delivery criteria were evaluated.

Composition and Label Disclosure100

An ingredient-specific warning is recorded; the saved facts do not provide its wording.
Explicit Label Detail
The evaluation records an ingredient-specific warning, but its wording is not available in the saved facts.

Commercial Price and Usability

No price criterion was evaluated.
View ingredientView products
88 Performance

Full Spectrum St. John's Wort Extract 600 mg

Planetary Herbals
A standardized, substantial Saint John’s wort blend offers focused mood support with stronger potency clarity than nonstandardized options; its extract quality and goal fit provide a clearer option when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
84 Performance

Feeling Positive St. John's Wort 300 mg

Sundown
Marker standardization supports consistent extract quality, though the daily amount is moderate; its extract quality and goal fit provide a clearer option when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
83 Performance

St. John's Wort Extract 300 mg

Lake Avenue Nutrition
A hypericin-standardized aerial-parts extract gives useful potency clarity and focused mood support, though one serving may provide only a partial daily dose; its extract quality and goal fit provide a clearer option when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
90 Budget

St. John's Wort Extract

Swanson Superior Herbs
Marker standardization supports consistent extract quality, though the daily amount is moderate; the lower serving cost improves economy when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
90 Budget

St. John's Wort 300 mg

NOW
Marker standardization supports consistent extract quality, though the daily amount is moderate; the lower serving cost improves economy when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
78 Budget

St. John's Wort 375 mg

Swanson Premium Brand
A focused herb amount offers basic value, but missing standardization limits consistency; the lower serving cost improves economy when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
87 Value

St. John's Wort Extract 300 mg

Lake Avenue Nutrition
A hypericin-standardized aerial-parts extract gives useful potency clarity and focused mood support, though one serving may provide only a partial daily dose; the quality-to-cost balance is favorable when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
86 Value

St. John's Wort 300 mg

Nature's Bounty
Marker standardization supports consistent extract quality, though the daily amount is moderate; the quality-to-cost balance is favorable when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
86 Value

Perika St. John's Wort

Nature's Way
The named extract supports consistent quality, though the daily amount is moderate; the quality-to-cost balance is favorable when the original already has a credible Saint John’s wort profile. Saint John’s wort can weaken oral contraceptives and anticoagulants and can interact seriously with serotonergic antidepressants, so medication use needs clinician or pharmacist review.
Report alternatives

Sources

Published studies used for the product analysis and the top-ranked studies for each ingredient and goal.

  1. St John's wort for major depression.
    Linde K; Berner MM; Kriston L · The Cochrane database of systematic reviews · 2009
    Systematic review5,489 participants29 studies pooledMood Support forSt. John's Wort
  2. Efficacy of St. John's wort extract WS 5570 in major depression: a double-blind, placebo-controlled trial.
    Lecrubier Y; Clerc G; Didi R; Kieser M · The American journal of psychiatry · 2002
    Randomized trial375 participantsMood Support forSt. John's Wort
  3. A systematic review and meta-analysis of Hypericum perforatum in depression: a comprehensive clinical review.
    Whiskey E; Werneke U; Taylor D · International clinical psychopharmacology · 2002
    Meta-analysis22 studies pooledMood Support forSt. John's Wort
  4. Efficacy and tolerability of hypericum extract WS 5572 versus placebo in mildly to moderately depressed patients. A randomized double-blind multicenter clinical trial.
    Kalb R; Trautmann-Sponsel RD; Kieser M · Pharmacopsychiatry · 2001
    Randomized trial72 participantsMood Support forSt. John's Wort
  5. Complementary therapies for clinical depression: an overview of systematic reviews.
    Haller H; Anheyer D; Cramer H; Dobos G · BMJ open · 2020
    Systematic review26 studies pooledMood Support forSt. John's Wort
  6. Comparison of St John's wort and imipramine for treating depression: randomised controlled trial.
    Woelk H · BMJ (Clinical research ed.) · 2000
    Randomized trial324 participantsStress Relief forSt. John's Wort
  7. Differential therapy of mild to moderate depressive episodes (ICD-10 F 32.0; F 32.1) with St. John's wort.
    Friede M; Henneicke von Zepelin HH; Freudenstein J · Pharmacopsychiatry · 2002
    Randomized trial240 participantsStress Relief forSt. John's Wort
  8. Kava and St. John's Wort: current evidence for use in mood and anxiety disorders.
    Sarris J; Kavanagh DJ · Journal of alternative and complementary medicine (New York, N.Y.) · 2009
    Systematic reviewStress Relief forSt. John's Wort
  9. Do early changes in the HAM-D-17 anxiety/somatization factor items affect the treatment outcome among depressed outpatients? Comparison of two controlled trials of St John's wort (Hypericum perforatum) versus a SSRI.
    Bitran S; Farabaugh AH; Ameral VE; LaRocca RA; Clain AJ; Fava M; Mischoulon D · International clinical psychopharmacology · 2012
    Other475 participantsStress Relief forSt. John's Wort
  10. Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review.
    Lakhan SE; Vieira KF · Nutrition journal · 2011
    Systematic review2,619 participants24 studies pooledStress Relief forSt. John's Wort